{"title":"Strengthening TikTok Content Analysis in Academia Using Follower Count and Engagement.","authors":"Serena Ramjee, Zeeshaan-Ul Hasan","doi":"10.2196/54439","DOIUrl":"10.2196/54439","url":null,"abstract":"","PeriodicalId":73553,"journal":{"name":"JMIR dermatology","volume":"7 ","pages":"e54439"},"PeriodicalIF":0.0,"publicationDate":"2024-01-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10865194/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139577212","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Blair W Harris, Luke Maxfield, Abigail Hunter, Mandy Alhajj, Byung Ban, Kayd J Pulsipher
{"title":"Worldwide Distribution and Extracutaneous Manifestations of Henoch-Schönlein Purpura in Adults: Narrative Review.","authors":"Blair W Harris, Luke Maxfield, Abigail Hunter, Mandy Alhajj, Byung Ban, Kayd J Pulsipher","doi":"10.2196/49746","DOIUrl":"10.2196/49746","url":null,"abstract":"<p><strong>Background: </strong>Henoch-Schönlein purpura (HSP), a leukocytoclastic small vessel vasculitis, exhibits both cutaneous and systemic manifestations. While predominantly observed in childhood, it may manifest in adults with more pronounced systemic involvement. Furthermore, HSP is a global phenomenon showcasing epidemiological and systemic variances.</p><p><strong>Objective: </strong>This study aims to scrutinize extracutaneous manifestations in adults with HSP, discerning distinctions according to geographical regions on a worldwide scale.</p><p><strong>Methods: </strong>A comprehensive search encompassing PubMed, Embase, Cochrane Library, and Web of Science was executed, covering papers published from January 1, 1970, to December 1, 2019. Keywords used included \"Henoch-Schönlein purpura,\" \"henoch schonlein purpura+adult,\" \"IgA vasculitis+adult,\" \"HSP+adult,\" and \"IgAV.\" A total of 995 publications were identified, from which 42 studies encompassing 4064 patients were selected, with a predominant focus on cases reported in Asia, Europe, and the Americas.</p><p><strong>Results: </strong>Among adults afflicted with HSP, European patients exhibited a higher propensity for male predominance (P<.001), gastrointestinal involvement (P<.001), and musculoskeletal complications (P<.001). Conversely, patients from the Americas were least likely to experience genitourinary involvement (P<.001).</p><p><strong>Conclusions: </strong>HSP demonstrates a variance in distribution and extracutaneous manifestations within distinct geographical boundaries. In the adult population, European patients exhibited a higher prevalence of male gender and gastrointestinal and musculoskeletal involvement. Asian patients were more predisposed to genitourinary involvement when compared to their American counterparts. The establishment of prospective studies using standardized reporting measures is imperative to validate the relationships unveiled in this investigation.</p>","PeriodicalId":73553,"journal":{"name":"JMIR dermatology","volume":"7 ","pages":"e49746"},"PeriodicalIF":0.0,"publicationDate":"2024-01-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10853858/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139565436","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"An Unusual Case of Anderson-Fabry Disease: Case Report.","authors":"Alpana Mohta, Achala Mohta, Pramila Kumari","doi":"10.2196/49573","DOIUrl":"10.2196/49573","url":null,"abstract":"<p><p>Angiokeratoma is a group of capillary malformations characterized by the formation of variably sized dark red hyperkeratotic papules. Initially, it was believed that angiokeratoma corporis diffusum was a telltale sign of Anderson-Fabry disease; however, current consensus states that it is also seen in various other lysosomal enzymatic deficiencies. In this report, we present the case of a 12-year-old boy who developed angiokeratoma corporis diffusum with sensorineural deafness, acroparesthesias, and renal involvement.</p>","PeriodicalId":73553,"journal":{"name":"JMIR dermatology","volume":"7 ","pages":"e49573"},"PeriodicalIF":0.0,"publicationDate":"2024-01-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10828944/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139473157","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Emily Eachus, Kayla Schwartz, Taha Rasul, Daniel Bergholz, Jonette Keri, Armen Henderson
{"title":"REDCap as a Platform for Cutaneous Disease Management in Street Medicine: Descriptive Study.","authors":"Emily Eachus, Kayla Schwartz, Taha Rasul, Daniel Bergholz, Jonette Keri, Armen Henderson","doi":"10.2196/48940","DOIUrl":"10.2196/48940","url":null,"abstract":"","PeriodicalId":73553,"journal":{"name":"JMIR dermatology","volume":"7 ","pages":"e48940"},"PeriodicalIF":0.0,"publicationDate":"2024-01-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10806445/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139405446","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Reflecting on Decades of Data: The Global Burden of Disease-Cochrane Project.","authors":"Madeline Adelman, Isaac Weber","doi":"10.2196/41323","DOIUrl":"10.2196/41323","url":null,"abstract":"","PeriodicalId":73553,"journal":{"name":"JMIR dermatology","volume":"7 ","pages":"e41323"},"PeriodicalIF":0.0,"publicationDate":"2024-01-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10799281/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139099281","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Andrew J McNeil, Kelsey Parks, Xiaoqi Liu, Bohan Jiang, Joseph Coco, Kira McCool, Daniel Fabbri, Erik P Duhaime, Benoit M Dawant, Eric R Tkaczyk
{"title":"Crowdsourcing Skin Demarcations of Chronic Graft-Versus-Host Disease in Patient Photographs: Training Versus Performance Study.","authors":"Andrew J McNeil, Kelsey Parks, Xiaoqi Liu, Bohan Jiang, Joseph Coco, Kira McCool, Daniel Fabbri, Erik P Duhaime, Benoit M Dawant, Eric R Tkaczyk","doi":"10.2196/48589","DOIUrl":"10.2196/48589","url":null,"abstract":"<p><strong>Background: </strong>Chronic graft-versus-host disease (cGVHD) is a significant cause of long-term morbidity and mortality in patients after allogeneic hematopoietic cell transplantation. Skin is the most commonly affected organ, and visual assessment of cGVHD can have low reliability. Crowdsourcing data from nonexpert participants has been used for numerous medical applications, including image labeling and segmentation tasks.</p><p><strong>Objective: </strong>This study aimed to assess the ability of crowds of nonexpert raters-individuals without any prior training for identifying or marking cGHVD-to demarcate photos of cGVHD-affected skin. We also studied the effect of training and feedback on crowd performance.</p><p><strong>Methods: </strong>Using a Canfield Vectra H1 3D camera, 360 photographs of the skin of 36 patients with cGVHD were taken. Ground truth demarcations were provided in 3D by a trained expert and reviewed by a board-certified dermatologist. In total, 3000 2D images (projections from various angles) were created for crowd demarcation through the DiagnosUs mobile app. Raters were split into high and low feedback groups. The performances of 4 different crowds of nonexperts were analyzed, including 17 raters per image for the low and high feedback groups, 32-35 raters per image for the low feedback group, and the top 5 performers for each image from the low feedback group.</p><p><strong>Results: </strong>Across 8 demarcation competitions, 130 raters were recruited to the high feedback group and 161 to the low feedback group. This resulted in a total of 54,887 individual demarcations from the high feedback group and 78,967 from the low feedback group. The nonexpert crowds achieved good overall performance for segmenting cGVHD-affected skin with minimal training, achieving a median surface area error of less than 12% of skin pixels for all crowds in both the high and low feedback groups. The low feedback crowds performed slightly poorer than the high feedback crowd, even when a larger crowd was used. Tracking the 5 most reliable raters from the low feedback group for each image recovered a performance similar to that of the high feedback crowd. Higher variability between raters for a given image was not found to correlate with lower performance of the crowd consensus demarcation and cannot therefore be used as a measure of reliability. No significant learning was observed during the task as more photos and feedback were seen.</p><p><strong>Conclusions: </strong>Crowds of nonexpert raters can demarcate cGVHD images with good overall performance. Tracking the top 5 most reliable raters provided optimal results, obtaining the best performance with the lowest number of expert demarcations required for adequate training. However, the agreement amongst individual nonexperts does not help predict whether the crowd has provided an accurate result. Future work should explore the performance of crowdsourcing in standard clinical p","PeriodicalId":73553,"journal":{"name":"JMIR dermatology","volume":"6 ","pages":"e48589"},"PeriodicalIF":0.0,"publicationDate":"2023-12-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10777279/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139038272","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Ramiro Rodriguez, Torunn E Sivesind, Dedee Murrell, Robert P Dellavalle
{"title":"From the Cochrane Library: Interventions for Pemphigus Vulgaris and Pemphigus Foliaceus.","authors":"Ramiro Rodriguez, Torunn E Sivesind, Dedee Murrell, Robert P Dellavalle","doi":"10.2196/46812","DOIUrl":"10.2196/46812","url":null,"abstract":"","PeriodicalId":73553,"journal":{"name":"JMIR dermatology","volume":" ","pages":"e46812"},"PeriodicalIF":0.0,"publicationDate":"2023-12-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10757221/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44346439","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Ross O'Hagan, Dina Poplausky, Jade N Young, Nicholas Gulati, Melissa Levoska, Benjamin Ungar, Jonathan Ungar
{"title":"The Accuracy and Appropriateness of ChatGPT Responses on Nonmelanoma Skin Cancer Information Using Zero-Shot Chain of Thought Prompting.","authors":"Ross O'Hagan, Dina Poplausky, Jade N Young, Nicholas Gulati, Melissa Levoska, Benjamin Ungar, Jonathan Ungar","doi":"10.2196/49889","DOIUrl":"10.2196/49889","url":null,"abstract":"","PeriodicalId":73553,"journal":{"name":"JMIR dermatology","volume":"6 ","pages":"e49889"},"PeriodicalIF":0.0,"publicationDate":"2023-12-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10755659/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138815263","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"A Mobile Health App for Facilitating Disease Management in Children With Atopic Dermatitis: Feasibility and Impact Study.","authors":"Alex Zvulunov, Stepan Lenevich, Natalia Migacheva","doi":"10.2196/49278","DOIUrl":"10.2196/49278","url":null,"abstract":"<p><strong>Background: </strong>Inadequate control of atopic dermatitis (AD) increases the frequency of exacerbations and reduces the quality of life. Mobile health apps provide information and communication technology and may increase treatment adherence and facilitate disease management at home. The mobile health app, Atopic App, designed for patients and their caregivers, and the associated web-based patient education program, Atopic School, provide an opportunity for improving patients' and caregivers' engagement and adherence to the management of AD.</p><p><strong>Objective: </strong>This noninterventional, observational study aimed to explore the feasibility and potential impact on the management of AD in children by caregivers using the Atopic App mobile health app.</p><p><strong>Methods: </strong>The patient-oriented eczema measure (POEM) and numerical rating scale for the grading of pruritus were used as severity scores (scale range: 0-28). The artificial intelligence model of the app was used to assess the severity of AD based on the eczema area and severity index approach. The deidentified data enabled the analysis of the severity of AD, treatment plan history, potential triggers of flare-ups, usage of available features of the app, and the impact of patient education.</p><p><strong>Results: </strong>During a 12-month period, of the 1223 users who installed the app, 910 (74.4%) registered users were caregivers of children with AD. The web-based Atopic School course was accessed by 266 (29.2%) caregivers of children with AD, 134 (50.4%) of whom completed the course. Usage of the app was significantly more frequent among those who completed the Atopic School program than among those who did not access or did not complete the course (P<.001). Users who completed a second POEM 21 to 27 days apart exhibited a significant improvement of AD severity based on the POEM score (P<.001), with an average improvement of 3.86 (SD 6.85) points. The artificial intelligence severity score and itching score were highly correlated with the POEM score (r=0.35 and r=0.52, respectively).</p><p><strong>Conclusions: </strong>The Atopic App provides valuable real-world data on the epidemiology, severity dynamics, treatment patterns, and exacerbation-trigger correlations in patients with AD. The significant reduction in the POEM score among users of the Atopic App indicates a potential impact of this tool on health care engagement by caregivers of children with AD.</p>","PeriodicalId":73553,"journal":{"name":"JMIR dermatology","volume":"6 ","pages":"e49278"},"PeriodicalIF":0.0,"publicationDate":"2023-12-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10753416/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138815262","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}