JCPP advancesPub Date : 2026-09-13Epub Date: 2026-01-03DOI: 10.1002/jcv2.70091
Emma Butler, Michelle Spirtos, Linda M. O’Keeffe, Mary Clarke
{"title":"Predicting 7-year-olds mental health in the perinatal period: Development and internal validation of a multivariable model using the prospective ALSPAC cohort","authors":"Emma Butler, Michelle Spirtos, Linda M. O’Keeffe, Mary Clarke","doi":"10.1002/jcv2.70091","DOIUrl":"10.1002/jcv2.70091","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Background</h3>\u0000 \u0000 <p>Mental health difficulties in childhood are increasing. Prevention is the only sustainable and ethical public health approach. However, predicting which children are most at-risk of mental health difficulties prior to symptoms emerging remains elusive.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Methods</h3>\u0000 \u0000 <p>We developed and internally validated a perinatal multivariable model, predicting 7-year-olds mental health, using the Avon Longitudinal Study of Parents and Children (<i>N</i> = 6021, 51.2% male, 98.6% White). Perinatal predictors were reported by the mother prospectively in pregnancy and the Strengths and Difficulties Questionnaire (SDQ) was completed by the mother at 7-years-old. This was dichotomised at recommended clinical cut-off (total>16) Building on our previous model in a French cohort, 15 perinatal parameters spanning maternal pre-pregnancy health, biological and psychosocial pregnancy-specific-experiences, maternal health behaviours in pregnancy and sociodemographic factors were entered into a logistic regression using the least absolute selection and shrinkage operator. Optimism-adjusted estimates were achieved using bootstrapping. Model performance was stratified by sex, sociodemographic risk and admission to a special-care baby unit.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>Combining eight variables predicted poor mental health, with a C-statistic of 0.66; 95% Confidence-Interval (0.64–0.68). It accurately predicted 85.6% of the participants mental health at 7-years in the perinatal period. Model performance was similar across groups of interest. Applying this model leads to a higher benefit than serving ‘all’ or ‘no’ children, that is, using the model, 30.9% of children who later had poor mental health would have been identified in the perinatal period.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusion</h3>\u0000 \u0000 <p>It is possible to predict childhood mental health at birth with moderate accuracy. Similar patterns of model performance were observed in this English cohort compared to a previous French cohort. At population-level, the model is most useful for ruling-out babies who are not predicted to be high-risk. In addition to improving its positive predictive value and external validation, future research should examine the model's performance at service-delivery level before implementation.</p>\u0000 </section>\u0000 </div>","PeriodicalId":73542,"journal":{"name":"JCPP advances","volume":"6 3","pages":""},"PeriodicalIF":4.1,"publicationDate":"2026-09-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13339273/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148407192","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
JCPP advancesPub Date : 2026-09-13Epub Date: 2026-01-22DOI: 10.1002/jcv2.70096
Marianne G. Chirica, Lauren O’Reilly, Cheryl A. King, Steven A. Miller
{"title":"Predicting six month follow-up of suicidal thoughts and attempts among youth with anxiety presenting to an emergency department","authors":"Marianne G. Chirica, Lauren O’Reilly, Cheryl A. King, Steven A. Miller","doi":"10.1002/jcv2.70096","DOIUrl":"10.1002/jcv2.70096","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Background</h3>\u0000 \u0000 <p>Previous research has established an association between anxiety disorders and suicidal thoughts and attempts; however, much remains unknown about the role of specific anxiety symptoms, anxiety severity, and the impact of co-occurring depression and hopelessness. This study examined (a) the independent relationship between anxiety severity and suicidal thoughts and attempts, and (b) the independent relationships between different anxiety symptoms and suicidal thoughts and attempts. Additionally, we analyzed a subset of youth with anxiety symptoms to examine, (c) depression severity and hopelessness as predictors of suicidal thoughts and attempts.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Methods</h3>\u0000 \u0000 <p>Participants were 2104 youth (ages 12–17) who presented to an Emergency Department (ED) from the Emergency Department Screen for Teens at Risk for Suicide (ED-STARS) cohort. Youth self-reported anxiety, depression, and hopelessness at baseline and reported suicidal thoughts and attempt at three- and/or 6-month follow-up. Among the subset of 652 youth with anxiety (≥3 on SCARED-C), depression and hopelessness were examined as predictors of suicidal thoughts and attempts.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>Anxiety severity significantly predicted ideation at follow-up, even after accounting for demographics (race/ethnicity, sex, parental education, welfare), depression, hopelessness, and previous suicide attempts (OR = 1.08, 95% CI [1.01–1.61]). However, anxiety severity did not predict suicide attempts after accounting for depression. Specific anxiety domains were not associated with attempts, and only separation anxiety was associated with ideation (OR = 1.04, 95% CI [1.00–1.08]). Among the subset of youth reporting anxiety, depression severity was associated with suicide attempts at follow-up, (OR = 1.08, 95% CI [1.04–1.14]). Depression (OR = 1.11, 95% CI [1.08–1.15]) and hopelessness (OR = 1.03, 95% CI [1.01–1.05]) each uniquely predicted suicidal ideation.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusion</h3>\u0000 \u0000 <p>Anxiety severity, rather than specific anxiety domains, may drive subsequent suicidal thoughts and attempts. Among youth with anxiety, depression predicted both attempts and ideation at follow-up, whereas hopelessness predicted only ideation. Shared aspects of anxiety and depression may underlie youth suicide risk.</p>\u0000 </section>\u0000 </div>","PeriodicalId":73542,"journal":{"name":"JCPP advances","volume":"6 3","pages":""},"PeriodicalIF":4.1,"publicationDate":"2026-09-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13339218/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148407232","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
JCPP advancesPub Date : 2026-09-13Epub Date: 2025-12-08DOI: 10.1002/jcv2.70084
Anna Pezzella, Pietro Buono, Nadia Marani, Luisa Almerico, Alessandra Carta, Maria Nobile, Carmela Bravaccio, Gennaro Catone, Vincenzo Paolo Senese, Simone Pisano
{"title":"Cyclothymic-hypersensitive temperament in early adolescence: Longitudinal measurement invariance and associations with psychopathology over time","authors":"Anna Pezzella, Pietro Buono, Nadia Marani, Luisa Almerico, Alessandra Carta, Maria Nobile, Carmela Bravaccio, Gennaro Catone, Vincenzo Paolo Senese, Simone Pisano","doi":"10.1002/jcv2.70084","DOIUrl":"10.1002/jcv2.70084","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Background</h3>\u0000 \u0000 <p>Cyclothymic-Hypersensitive Temperament (CHT) is characterised by mood instability, interpersonal hypersensitivity, and emotional hyperreactivity, traits frequently observed in general population as well as clinical settings but often eluding strict diagnostic classifications. CHT offers valuable insights into adolescents' emotional and behavioural patterns, but further research is needed to explore its longitudinal associations with psychopathology and clarify its clinical significance.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Methods</h3>\u0000 \u0000 <p>Data were collected from 780 students (50.1% male, mean age at first assessment: 11.35 ± 0.49 years). The study used a longitudinal design with two assessments 2 years apart. Psychopathological symptoms were assessed using the Strength and Difficulties Questionnaire, whereas CHT Questionnaire (CHTQ) assessed CHT. Longitudinal Measurement Invariance of the CHTQ was tested to ensure construct consistency, and a Cross-Lagged Panel Model (CLPM) was used to examine bidirectional relationships between CHT and psychopathology over time.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>The CHTQ demonstrated configural, metric, scalar, and strict invariance throughout time, confirming its robustness and stability. The CLPM revealed a substantial stability of CHT across time (<i>b</i> = 0.430, SE = 0.078, 95% CI [0.277, 0.583], <i>β</i> = 0.475, <i>p</i> < 0.001) and a specific significant longitudinal association between CHT and psychopathology (<i>b</i> = 0.290, SE = 0.103, 95% CI [0.088, 0.492], <i>β</i> = 0.256, <i>p</i> < 0.001).</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusion</h3>\u0000 \u0000 <p>The demonstrated invariance underscores the CHTQ's value as a reliable tool for future research on developmental trajectories and longitudinal patterns of CHT in early adolescence. CHT plays a key role in the onset of early psychopathological symptoms, positioning it within a psychopathological framework.</p>\u0000 </section>\u0000 </div>","PeriodicalId":73542,"journal":{"name":"JCPP advances","volume":"6 3","pages":""},"PeriodicalIF":4.1,"publicationDate":"2026-09-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13339416/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148406923","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
JCPP advancesPub Date : 2026-09-13Epub Date: 2025-12-04DOI: 10.1002/jcv2.70077
Vladislav Ruchkin, Andrew Stickley, Mary Schwab-Stone, Johan Isaksson
{"title":"Posttraumatic stress, perceived hostile intention and reactions to peer provocation: A longitudinal study in US inner-city youth","authors":"Vladislav Ruchkin, Andrew Stickley, Mary Schwab-Stone, Johan Isaksson","doi":"10.1002/jcv2.70077","DOIUrl":"10.1002/jcv2.70077","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Background</h3>\u0000 \u0000 <p>Previous studies indicated that perceived hostile intention may mediate the link between traumatic experiences and aggressive behaviors, but the longitudinal associations between posttraumatic stress (PTS) and reactions to perceived provocation in adolescents have been underexplored. This study examined the longitudinal impact of PTS on the responses to and attribution of intentionality in peer provocation.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Methods</h3>\u0000 \u0000 <p>The study was conducted with a representative sample of predominantly ethnic minority youth (<i>N</i> = 2014; 50.5% female; age 12–14 years old (<i>M</i> (SD) = 12.19 (0.83)); 60.6% African-American, 27.6% Hispanic American, 10.1% White). The participants completed self-reports on PTS in year 1 and appraised responses to hypothetical peer provocation scenarios that adolescents can encounter in their daily lives in year 2.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>Higher levels of PTS were associated with more frequent choices of physical and verbal aggression, retaliation, teacher mediation, a less frequent choice of ignoring the situation and higher perceived hostile intention behind provocation. Compared to their female counterparts, boys more frequently chose reactions of physical aggression and retaliation, while girls more frequently reported verbal aggression and negotiation strategies. An interaction effect of PTS by gender suggested that compared to girls, boys with higher levels of PTS had more difficulty ignoring perceived peer provocation. Perceived hostile intention fully or partially mediated the association between PTS and physical aggression, verbal aggression, wish for retaliation, not being willing to negotiate, and the lower tendency to ignore provocation.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusion</h3>\u0000 \u0000 <p>High levels of PTS may significantly influence gender-specific patterns of aggressive responses during conflicts with peers, while perceived hostile intention seems to mediate these associations. These findings may be relevant for the rehabilitation of traumatized youth, and should be taken into account when planning the treatment of adolescents with PTS.</p>\u0000 </section>\u0000 </div>","PeriodicalId":73542,"journal":{"name":"JCPP advances","volume":"6 3","pages":""},"PeriodicalIF":4.1,"publicationDate":"2026-09-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13339556/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148407081","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
JCPP advancesPub Date : 2026-09-13Epub Date: 2025-11-25DOI: 10.1002/jcv2.70063
Ki Eun Shin, Ilana Gratch, Christine B. Cha
{"title":"Who and what retrospective risk assessments miss: Examining retrospective denial of momentary suicidal ideation in adolescents","authors":"Ki Eun Shin, Ilana Gratch, Christine B. Cha","doi":"10.1002/jcv2.70063","DOIUrl":"10.1002/jcv2.70063","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Background</h3>\u0000 \u0000 <p>Emerging evidence indicates that real-time assessments such as ecological momentary assessment (EMA) detect individuals experiencing suicidal ideation (SI) who go undetected by retrospective assessments. However, it remains unclear for whom and why such discrepancies occur. Few prior studies accounted for method variance (e.g., survey vs. interview), and no studies have comprehensively examined which individual characteristics differentiate those with and without discrepant reports across EMA and retrospective measures. The current study aimed to address these gaps by examining discrepancies in SI endorsement across EMA and two forms of retrospective measures (survey, interview), as well as comparing those with and without discrepant reports on demographic, clinical, and EMA-based variables.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Methods</h3>\u0000 \u0000 <p>Eighty community-based adolescents completed a baseline online survey assessing demographic and clinical characteristics, followed by a 14-day EMA assessing momentary SI (5x/day). At the conclusion of the EMA period, adolescents retrospectively reported their SI during the past 2 weeks via a survey and an interview.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>Of 48 adolescents who endorsed some SI during EMA, 35%–41% retrospectively denied having experienced SI during the EMA period on the follow-up survey and interview. Adolescents with retrospective denial had a lower likelihood of lifetime SI (<i>ps</i> < 0.05, <i>φ</i><sub><i>c</i></sub> = 0.53–0.55), lower SI and depression severity (<i>ps</i> < 0.05, <i>ds</i> = 0.52–0.64), and lower hopelessness at baseline (<i>ps</i> < 0.05, <i>ds</i> = 0.56–0.60), as well as less frequent and less severe SI (<i>ps</i> < 0.05, <i>ds</i> = 0.32–0.72) during EMA compared to those who endorsed SI across both EMA and retrospective measures.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusion</h3>\u0000 \u0000 <p>Real-time monitoring detects more adolescents experiencing SI than retrospective assessments, particularly those with lower clinical severity. Therefore, real-time monitoring has the potential to facilitate early interventions by identifying adolescents who are not yet as advanced in the suicide risk trajectory but are at risk of further escalation.</p>\u0000 </section>\u0000 </div>","PeriodicalId":73542,"journal":{"name":"JCPP advances","volume":"6 3","pages":""},"PeriodicalIF":4.1,"publicationDate":"2026-09-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13337130/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148407122","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
JCPP advancesPub Date : 2026-09-13Epub Date: 2026-01-31DOI: 10.1002/jcv2.70099
Rosa Sparks, Gary Kainth, Helen Minnis, Jala Rizeq
{"title":"A systematic review and meta-analysis examining the impact of placement instability on the mental health outcomes of care experienced children and young people","authors":"Rosa Sparks, Gary Kainth, Helen Minnis, Jala Rizeq","doi":"10.1002/jcv2.70099","DOIUrl":"10.1002/jcv2.70099","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Background</h3>\u0000 \u0000 <p>Care experienced children and young people (CECYP) are at risk of mental health difficulties. This review aimed to examine the impact of placement instability on the mental health outcomes of CECYP and to explore how placement instability is measured.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Methods</h3>\u0000 \u0000 <p>This review was conducted following the PRISMA guidance. Four databases (PsycINFO, Embase, Medline and ProQuest) were initially searched on 14<sup>th</sup> December 2023, with an updated search conducted on January 29<sup>th</sup> 2025. The following inclusion criteria were used: quantitative observational studies, CECYP (0–18 years), mental health difficulties as the outcome and placement instability as the exposure. The quality of the included studies was also assessed. The results from all papers included in the review were narratively synthesised and results from a subsample of the papers eligible for quantitative synthesis were analysed using a random effects meta-analysis to examine the association between placement instability and mental health outcomes of CECYP.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>Twenty-two studies were eligible for inclusion. The measurement of placement instability varied with some studies counting number of placement moves and some grouping number of moves into levels. The time frames in which moves were measured also varied. Overall, placement instability had a negative impact on mental health outcomes in CECYP, irrespective of age, sex, domain of mental health assessed (internalising and externalising), and initial levels of mental health. The meta-analysis found that placement instability had a small significant association with both internalising (<i>r =</i> 0.14, 95% CI = 0.12, 0.17) and externalising (<i>r =</i> 0.14, 95% CI = 0.11, 0.18) mental health difficulties.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusion</h3>\u0000 \u0000 <p>Placement instability is inconsistently measured and defined in the literature. Despite this heterogeneity in operationalisation, it remains a concerning risk factor for mental health difficulties of CECYP. Efforts should be made to minimise instability for this population.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Trial Registration</h3>\u0000 \u0000 <p>The protocol was registered on PROSPERO on the 2nd of February 2024 (CRD42024444031), can be found at https://www.crd.york.ac.uk/PROSPERO/view/CRD42024444031.</p>\u0000 </section>\u0000 </div>","PeriodicalId":73542,"journal":{"name":"JCPP advances","volume":"6 3","pages":""},"PeriodicalIF":4.1,"publicationDate":"2026-09-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13339400/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148407158","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
JCPP advancesPub Date : 2026-09-13Epub Date: 2026-03-25DOI: 10.1002/jcv2.70114
Charlotte Robinson, Katherine H. Shelton, Lisa Holmes, Bethan Carter, Eva A. Sprecher, Ace Garmadon, Clo H, Rachel M. Hiller
{"title":"Editorial perspective: Facilitating access to mental health research participation for children in care: Lessons from the ReThink project","authors":"Charlotte Robinson, Katherine H. Shelton, Lisa Holmes, Bethan Carter, Eva A. Sprecher, Ace Garmadon, Clo H, Rachel M. Hiller","doi":"10.1002/jcv2.70114","DOIUrl":"10.1002/jcv2.70114","url":null,"abstract":"<p>Children in care have historically been under-represented in mental health research, despite high levels of need. Consequently, there is a lack of high-quality empirical evidence to drive advocacy, practise, and policy, and the direct voice of children in care is often absent. In this Editorial Perspective, we outline three key areas of consideration, that must be understood and addressed to maximise the success of primary mental health research with this group of children. Specifically, we focus on: capacity issues in children's social care and partnership working; consent and assent procedures; and supporting children in care through mental health research. The paper is informed by the ReThink Project, a longitudinal mixed-methods study involving 450 care-experienced young people across 13 local authorities in England and Wales. The issues and solutions we discuss have implications for future study design, including timelines and funding.</p>","PeriodicalId":73542,"journal":{"name":"JCPP advances","volume":"6 3","pages":""},"PeriodicalIF":4.1,"publicationDate":"2026-09-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13339523/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148407085","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
JCPP advancesPub Date : 2026-09-13Epub Date: 2025-12-17DOI: 10.1002/jcv2.70082
Konstantin Drexl, Setareh Ranjbar, Sébastien Urben, Kerstin Jessica Plessen, Jennifer Glaus
{"title":"Toward an idiographic understanding of the role of sleep-mood dynamics in adolescents' internalizing symptoms","authors":"Konstantin Drexl, Setareh Ranjbar, Sébastien Urben, Kerstin Jessica Plessen, Jennifer Glaus","doi":"10.1002/jcv2.70082","DOIUrl":"10.1002/jcv2.70082","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Background</h3>\u0000 \u0000 <p>Adolescence is marked by increased vulnerability to sleep disturbances and mood disorders. Understanding how day-to-day changes in sleep and mood are linked within the same individual is crucial for clarifying sleep's role in emerging internalizing disorders. However, the extent to which an adolescent's fluctuations in sleep predict next-day mood may differ across individuals. This study examined such differences in person-specific sleep-mood dynamics and their links with depression and anxiety symptoms.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Methods</h3>\u0000 \u0000 <p>A total of 113 Swiss adolescents (57% female, mean age = 15.4 years, SD = 0.97) participated in three 3-week waves of combined actigraphy, four daily Ecological Momentary Assessments (EMA), and weekly reports of depressive and anxiety symptoms. Bayesian multilevel models estimated person-specific associations across two mood dimensions (sad-vs-happy and anxious-vs-calm) combined with sleep duration (SDur), sleep midpoint (SMid), and sleep regularity (SReg; i.e., overlap between each daily cycle and the participant's most typical cycle). Bayesian hypothesis tests examined evidence for differences in person-specific associations and whether these differences predicted internalizing symptoms.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>Person-specific associations involving SDur or SMid showed within-person effects at the group-level, but no convincing evidence for individual differences in this dynamic. In contrast, there were clear individual differences in how SReg related to anxious-vs-calm mood (<i>τ</i><sup>2</sup> = 0.47, [0.09; 0.79], BF<sub>10</sub> = 13.2). Adolescents whose calm mood was more strongly tied to a regular sleep–wake cycle reported fewer anxiety symptoms (<i>b</i> = 3.57, 95%CrI [-3.67; 9.31], BF<sub>01</sub> = 7.69).</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusion</h3>\u0000 \u0000 <p>Our findings suggest that adolescents whose daytime mood is closely coupled with regular sleep–wake patterns may experience protection against anxiety symptoms. They also show that adolescents differ meaningfully in these sleep–mood associations, challenging conventional group-level approaches. Future work should extend this idiographic approach to more diverse populations and longer timescales to clarify the role of sleep–mood dynamics in internalizing disorders.</p>\u0000 </section>\u0000 </div>","PeriodicalId":73542,"journal":{"name":"JCPP advances","volume":"6 3","pages":""},"PeriodicalIF":4.1,"publicationDate":"2026-09-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13339598/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148407127","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
JCPP advancesPub Date : 2026-09-13Epub Date: 2025-11-12DOI: 10.1002/jcv2.70067
Marika Leppänen, Miika Vuori, Bernd Pape, Anniina Kaittila, Siiri-Liisi Kraav, Tommi Tolmunen, Merja Anis, Max Karukivi, Päivi Rautava
{"title":"Trends in the incidence of attention deficit hyperactivity disorder in children and early risk factors","authors":"Marika Leppänen, Miika Vuori, Bernd Pape, Anniina Kaittila, Siiri-Liisi Kraav, Tommi Tolmunen, Merja Anis, Max Karukivi, Päivi Rautava","doi":"10.1002/jcv2.70067","DOIUrl":"10.1002/jcv2.70067","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Background</h3>\u0000 \u0000 <p>Few studies have used nationwide registry data from both primary and secondary healthcare services to examine the incidence of attention-deficit/hyperactivity disorder (ADHD) in children while accounting for early risk factors. We aimed to investigate trends in ADHD diagnoses and associated risk factors.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Methods</h3>\u0000 \u0000 <p>This study utilized data from population-based registers, comprising children born between 2001 and 2006 (<i>N</i> = 341,632), with follow-up data available up to age 12. Children who died perinatally, those with unclear or very low (<32 weeks) gestational age, as well as those with severe congenital syndromes or severe or unclear cognitive impairments were excluded. The main outcome was the cumulative incidence of ADHD, defined by ICD-10 codes F90, F90.0, F90.1, F90.8, F90.9, or F98.8. This outcome was adjusted for gestational age, sex, birth cohort, and maternal psychosocial factors during the child's first 3 years.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>The cumulative incidence of ADHD diagnosis at 0–12 years was 4.0% (3.9−4.0%) for the entire study (<i>N</i> = 324,766), 6.4% (6.2−6.5%) for boys, and 1.5% (1.5−1.6%) for girls. An ADHD diagnosis was more likely (adjusted odds ratios [95% confidence intervals]) among boys (4.6 [4.3–4.8]) and moderately preterm children (1.3 [1.2–1.4]), as well as in cases where the mother smoked during pregnancy (2.0 [1.9–2.1]), had a psychiatric disorder (2.0 [1.9–2.1]), or lived alone (1.4 [1.3–1.5]), compared to opposite condition. The cumulative incidence of ADHD diagnoses increased over time in both primary and secondary healthcare settings. There was a slight increase in the number of mothers diagnosed with any psychiatric disorder across cohorts, <i>p</i> < 0.0001.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusion</h3>\u0000 \u0000 <p>The cumulative incidence of ADHD diagnoses in healthcare has been increasing. While psychosocial risk factors are associated with an elevated risk of receiving an ADHD diagnosis, other factors may also contribute to the rising diagnostic rates.</p>\u0000 </section>\u0000 </div>","PeriodicalId":73542,"journal":{"name":"JCPP advances","volume":"6 3","pages":""},"PeriodicalIF":4.1,"publicationDate":"2026-09-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13339198/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148407079","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
JCPP advancesPub Date : 2026-09-13Epub Date: 2025-11-02DOI: 10.1002/jcv2.70066
Lu Zhang, Vanessa L. Cropley, Divyangana Rakesh, Sarah Whittle
{"title":"Neural correlates of resilience to trauma during adolescence: A multi-modal study","authors":"Lu Zhang, Vanessa L. Cropley, Divyangana Rakesh, Sarah Whittle","doi":"10.1002/jcv2.70066","DOIUrl":"10.1002/jcv2.70066","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Background</h3>\u0000 \u0000 <p>Understanding resilience mechanisms is important for advancing early intervention strategies, yet research on the neurobiology of resilience in adolescents is limited. The present study examined the brain structural and resting-state functional connectivity (rsFC) correlates of resilience to internalizing and externalizing symptoms in a large sample of adolescents.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Methods</h3>\u0000 \u0000 <p>We analyzed longitudinal data from 8499 adolescents (baseline mean age 9.92 ± 0.62 years) from the Adolescent Brain Cognitive Development Study. Participants were categorized as resilient, maladaptive, vulnerable, or control group based on reports of traumatic events and internalizing/externalizing symptoms 3 years later. We used multinomial regressions to examine associations of brain structure (gray matter, <i>N</i> = 7526; white matter, <i>N</i> = 6959) and rsFC (<i>N</i> = 6485) with resilience. Sex differences were also investigated.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>For internalizing symptoms, increased odds of being resilient (relative to controls) were associated with postcentral gyrus thickness. For externalizing symptoms, increased odds of being resilient was associated with putamen volume (relative to being vulnerable), and rsFC between the dorsal and ventral attention networks, and between cortical networks and hippocampus (relative to controls). Sex-interaction results implicated gray matter structure, however, robustness of these findings are limited.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusion</h3>\u0000 \u0000 <p>Resilience in the context of internalizing symptoms in adolescence may be associated with structural alterations in cortical regions involved sensory processing. Neural correlates of resilience in the context of externalizing symptoms remain unclear as findings may reflect resilience, trauma exposure, or psychopathology. This underscores the need for further research into the neurobiological basis of resilience during adolescence.</p>\u0000 </section>\u0000 </div>","PeriodicalId":73542,"journal":{"name":"JCPP advances","volume":"6 3","pages":""},"PeriodicalIF":4.1,"publicationDate":"2026-09-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13339669/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148407155","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}