JCPP advances最新文献

{"title":"Genetic and environmental influences on sleep quality, ability to settle, and crying duration in 2- and 5-month-old infants: A longitudinal twin study","authors":"Charlotte Viktorsson,&nbsp;Ashraf Yahia,&nbsp;Mark J. Taylor,&nbsp;Angelica Ronald,&nbsp;Kristiina Tammimies,&nbsp;Terje Falck-Ytter","doi":"10.1002/jcv2.70023","DOIUrl":"10.1002/jcv2.70023","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Background</h3>\u0000 \u0000 <p>Sleep and behavioral regulation are both vital for early healthy development. Yet, little is known about the relative contribution of genetic and environmental factors to early sleep and regulatory behaviors, or how these etiological influences may change during the first months of life.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Methods</h3>\u0000 \u0000 <p>Genetic and environmental influences on sleep, settle, and crying behaviors at 2 and 5 months were examined in 998 twins, using a classical twin design. In addition, polygenic scores were derived for a range of sleep behaviors, as well as psychiatric and neurodevelopmental conditions.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>Genetic influences (A) explained a large part of the variation in duration of crying at both 2 and 5 months (A = 0.29–0.70) and in settle ability at 5 months (A = 0.51–0.67). Shared environment (C) primarily influenced number of wakeups per night at both ages (C = 0.61–0.90) and settle ability at 2 months (C = 0.36–0.65). Longitudinal analyses suggested modest shared genetic influence on settle ability in the daytime across the ages (24%), and non-significant shared genetic estimates for ability to settle in the evening and at nighttime. There was moderate shared influence of shared environmental factors on number of wakeups per night (56%) and modest but significant shared genetic influence on crying duration in the evening and nighttime (17%–33%). Unique environmental effects were mostly specific to each age. Finally, autism polygenic score associated with longer crying duration in the evening at 2 months (<i>β</i> = 0.16, <i>p</i> = .002).</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusions</h3>\u0000 \u0000 <p>Etiological influences tended to change from 2 to 5 months, reflecting a highly plastic period in infant brain development and in child-environment interactions.</p>\u0000 </section>\u0000 </div>","PeriodicalId":73542,"journal":{"name":"JCPP advances","volume":"6 1","pages":""},"PeriodicalIF":3.1,"publicationDate":"2026-03-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12973126/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147438224","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"School experiences and self-harm in the OxWell study","authors":"Rasanat Fatima Nawaz,&nbsp;Tamsin Jane Ford,&nbsp;Mina Fazel,&nbsp;Galit Geulayov,&nbsp;The OxWell Study Team,&nbsp;Simon R. White","doi":"10.1002/jcv2.70025","DOIUrl":"10.1002/jcv2.70025","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Background</h3>\u0000 \u0000 <p>Schools are key for identifying challenges faced by young people who self-harm (SH). Understanding how school factors influence SH predictors is essential for developing effective school-based interventions. We aimed to conduct a secondary data analysis using the OxWell Student Survey to identify associations between young people's school experiences and SH.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Methods</h3>\u0000 \u0000 <p>Using cross-sectional data from English secondary schools in the 2023 OxWell Student Survey, we conducted multi-level logistic regressions to analyse whether SH was associated with student age, gender, mental health (RCADS) and wellbeing (sWEMWBS). School experience measures included enjoyment, bullying, racism, extracurricular activities, school worry, and adults listening.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>Individual students' perception that the school did not deal well with bullying were associated with a 38% increase in SH (OR = 1.38; CI 1.20–1.59) and schools not dealing well with racism was associated with a 20% increase in the likelihood of SH (OR = 1.20; CI 1.04–1.38). Similarly, the likelihood of SH was 30% higher in schools with students feeling unfairly picked on by their teacher (OR = 1.30; CI 1.14–1.47). Greater SH was associated with being female (OR = 1.15; CI 0.99–1.32), gender diverse (OR = 3.49; CI 2.38–5.12), or preferring not to say (OR = 2.02; CI 1.44–2.83) compared to males. Lower wellbeing scores (OR = 0.93; CI 0.93–0.95) and higher RCADS scores (OR = 1.12; CI 1.11–1.13) were also linked to higher SH likelihood.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusion</h3>\u0000 \u0000 <p>Interventions that address bullying, racism, teacher-pupil relationships as well as providing specific support for more vulnerable groups such as females and gender diverse young people are important components of public mental health interventions that might reduce levels of SH. Future research should explore these relationships longitudinally.</p>\u0000 </section>\u0000 </div>","PeriodicalId":73542,"journal":{"name":"JCPP advances","volume":"6 1","pages":""},"PeriodicalIF":3.1,"publicationDate":"2026-03-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12973120/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147437177","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Psychological and behavioral correlates of health anxiety and other anxiety phenomena in adolescence—A cross-sectional study in the Copenhagen Child Cohort 2000","authors":"Charlotte Steen Duholm,&nbsp;Davíð R. M. A. Højgaard,&nbsp;Kaare Bro Wellnitz,&nbsp;Eva Ørnbøl,&nbsp;Per Hove Thomsen,&nbsp;Martin Køster Rimvall,&nbsp;Charlotte Ulrikka Rask","doi":"10.1002/jcv2.70018","DOIUrl":"10.1002/jcv2.70018","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Background</h3>\u0000 \u0000 <p>Health anxiety (HA) is characterized by impairing worry about being or becoming seriously ill. This cross-sectional study aimed to explore psychological and behavioral correlates of HA compared to other anxiety phenomena in adolescents, that is, with respect to depression, physical symptoms, bodily dissatisfaction, health-related quality of life (HRQoL) and healthcare utilization.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Methods</h3>\u0000 \u0000 <p>This study was pre-registered at https://doi.org/10.17605/OSF.IO/YNBJG. We employed data from the 16/17-year follow-up (<i>N</i> = 2438, 16/17 years old) from the general population-based Copenhagen Child Cohort 2000. Health anxiety, anxiety, depression, physical symptoms, bodily dissatisfaction, and HRQoL were assessed using self-report questionnaires, and linked to register data on healthcare utilization. Latent profile and latent class analyses were applied to explore if specific HA related profiles/classes could be detected. These analyses did not support the idea of HA being independent of other anxieties. Instead, four groups were created based on levels of HA and anxiety symptoms. Differences between the four groups regarding the various health-related aspects were examined using relevant statistics.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>The four groups were: no anxieties (<i>N</i> = 1822; 74.7%), high other anxiety (<i>N</i> = 364; 14.9%), high HA (<i>N</i> = 111; 4.6%), and both high HA and other anxiety (<i>N</i> = 141; 5.8%). The high HA group reported fewer depressive symptoms, more physical symptoms, and higher healthcare utilization than those with high other anxiety. Compared to those without anxieties, both HA groups had worse scores on all psychological and behavioral correlates. Adolescents with both high HA and other anxiety symptoms reported most depressive and physical symptoms, highest bodily dissatisfaction, the lowest HRQoL and the highest healthcare utilization.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusion</h3>\u0000 \u0000 <p>HA symptoms often co-occur with additional anxiety symptoms but is specifically associated with significantly higher healthcare utilization, highlighting the importance of early recognition and intervention in youth to reduce its clinical impact.</p>\u0000 </section>\u0000 </div>","PeriodicalId":73542,"journal":{"name":"JCPP advances","volume":"6 1","pages":""},"PeriodicalIF":3.1,"publicationDate":"2026-03-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12973147/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147437208","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Correction to “Cultivating participatory processes in self-harm app development: A case-study and working methodology”","authors":"","doi":"10.1002/jcv2.70078","DOIUrl":"10.1002/jcv2.70078","url":null,"abstract":"<p>Babbage, C. M., Lockwood, J., Roberts, L., Mendes, J., Greenhalgh, C., Willingham, L.-P., Wokomah, E., Woodcock, R., Slovak, P., &amp; Townsend, E. (2024). Cultivating participatory processes in self-harm app development: A case-study and working methodology. JCPP Advances, 4(4), e12295. https://doi.org/10.1002/jcv2.12295.</p><p>In the Acknowledgements, Emma Nielsen was not included in the list of contributors associated with Digital Youth. The Acknowledgements should have been:</p><p>The contributors associated with Digital Youth With Sprouting Minds are as follows: Ellen Townsend; Chris Hollis; Jo Gregory; Elvira Perez Vallejos; Rebecca Woodcock; Peter Fonagy; Louise Arseneault; Sarah Doherty; Lucy-Paige Willingham; Cathy Creswell; Emily Lloyd; Josimar De Alcantara Mendes; Carolyn Ten Holter; Marina Jirotka; Praveetha Patalay; Yvonne Kelly; Aaron Kandola; Edmund Sonuga-Barke; Sonia Livingstone; Kasia Kostryka-Allchorne; Mariya Stoilova; Rory O'Connor; Dorothee Auer; Sieun Lee; Nitish Jawahar; Marianne Etherson; Chris Greenhalgh; Kapil Sayal; Jim Warren; Vajisha Wanniarachchi; Paul Stallard; Charlotte Hall; Mathijs Lucassen; Sally Merry; Karolina Stasiak; Camilla Babbage; Adam Parker; Holly Griffiths; Lily Roberts; Petr Slovak; Amy Jess Williams; Joanna Lockwood; <b>Emma Nielsen</b>.</p><p>In the “Second Workshops” section of Table 3, there are errors in the Gender column for Workshops 2 and 3. For Workshop 2, it should have been: Female = 4, and Male = 2. For Workshop 3, it should have been: Female = 3 and Male = 2. The correct table is:</p><p>We apologize for the errors.</p>","PeriodicalId":73542,"journal":{"name":"JCPP advances","volume":"6 1","pages":""},"PeriodicalIF":3.1,"publicationDate":"2026-03-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12973138/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147438185","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Characterising the classes of children and young people with mental health concerns based on reported service contact","authors":"Frances Mathews,&nbsp;Chris Playford,&nbsp;Obioha C. Ukoumunne,&nbsp;Tamsin J. Ford,&nbsp;Tamsin Newlove-Delgado","doi":"10.1002/jcv2.70014","DOIUrl":"10.1002/jcv2.70014","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Background</h3>\u0000 \u0000 <p>Exploring the similarities and differences of mental health-based service contact behaviours for children and young people (CYP) and associated characteristics will allow for distinct analysis of identified groups, and inform both current support pathways alongside more focussed targeted intervention strategies.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Methods</h3>\u0000 \u0000 <p>Using data from the Mental Health of CYP in England Survey, 2017, we fitted latent class analysis models to identify classes of CYP based on the type of service contact they received. Analysis was stratified by educational stage (aged 5–10, 11–16 and 17–19 years) owing to different help-seeking pathways.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>For each educational stage, the four-class model was the best fit. Latent classes for children aged 5–10 years included, No Services, Community Services, Nonmedical Services, Contact all services. Children and young people reported different patterns of class membership by gender and ethnic group. Similar latent classes were identified for YP aged 11–16 years including: No Services, Nonmedical Services, Community Services, and Contact all services, however, stronger patterns of contact were found for nonmedical compared to community services. For those aged 17–19 years, classes included: No Services, Nonmedical Services, Specialised Services and Community and Health Services. Young people in the Specialist Service class had higher probabilities of being white/other compared to Black/Asian/Mixed/Other.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusion</h3>\u0000 \u0000 <p>CYP show different patterns of service contact across educational stages, with gender and ethnic disparities. Our findings could inform models of help, and support those designing and commissioning services to refocus and review where funding is best placed.</p>\u0000 </section>\u0000 </div>","PeriodicalId":73542,"journal":{"name":"JCPP advances","volume":"6 1","pages":""},"PeriodicalIF":3.1,"publicationDate":"2026-03-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12973121/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147438218","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Differential impacts of parental attention deficit/hyperactivity disorder on early maternal-infant attachment","authors":"Elyse Mark,&nbsp;Brooke S. G. Molina,&nbsp;Michelle A. Wilson,&nbsp;Charles H. Zeanah,&nbsp;Heather M. Joseph","doi":"10.1002/jcv2.70029","DOIUrl":"10.1002/jcv2.70029","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Background</h3>\u0000 \u0000 <p>Parental attention deficit/hyperactivity disorder (ADHD) is associated with increased postpartum depressive symptoms and impaired daily functioning, potentially impacting early maternal-infant attachment (MIA).</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Methods</h3>\u0000 \u0000 <p>78 mothers, half with ADHD, were enrolled during pregnancy or postpartum. Participants completed questionnaires regarding social support, home chaos, postpartum depressive symptoms, and postnatal MIA. Pregnant participants (<i>n</i> = 45) also reported antenatal MIA. ANOVA compared mothers without ADHD (<i>n</i> = 44), mothers with ADHD (<i>n</i> = 21), and mothers with ADHD coparents (infants' fathers; <i>n</i> = 13), and Benjamini-Hochberg correction was applied to account for multiple testing. Multilevel linear regression examined predictors of MIA.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>Mothers with ADHD reported greater postpartum depressive symptoms and home chaos than mothers with ADHD coparents or those without parental ADHD; mothers with ADHD coparents reported the poorest overall MIA and quality of attachment and greatest hostility toward their infants (Benjamini-Hochberg false discovery rate <i>q</i> &lt; 0.05). In the final model for MIA, postpartum depressive symptoms (<i>B</i> = −0.85, <i>p</i> &lt; 0.001) and coparent ADHD (<i>B</i> = −4.70, <i>p</i> = 0.051) were associated with poorer MIA (<i>R</i>^<i>2</i> = 0.40, <i>p</i> &lt; 0.001). When examining MIA subscales, postpartum depressive symptoms were negatively correlated with subscales measuring quality of attachment and absence of hostility but not pleasure in mother-child interaction. When antenatal attachment was included, it (<i>B</i> = 0.65, <i>p</i> = 0.002), along with postpartum depressive symptoms (<i>B</i> = −0.60, <i>p</i> = 0.032), predicted postnatal MIA (<i>R</i>^<i>2</i> = 0.50, <i>p</i> &lt; 0.001).</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusions</h3>\u0000 \u0000 <p>Given parental ADHD (mother or father) was associated with increased maternal postpartum depressive symptoms and less optimal MIA in this study, additional support for families with ADHD in the perinatal period may improve maternal and infant mental health outcomes. Future work incorporating observational data and additional investigation of the coparenting relationship is needed to further clarify determinants of MIA in early childhood.</p>\u0000 </section>\u0000 </div>","PeriodicalId":73542,"journal":{"name":"JCPP advances","volume":"6 1","pages":""},"PeriodicalIF":3.1,"publicationDate":"2026-03-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12973118/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147438202","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Targeting intolerance of uncertainty in young children diagnosed with autism: A randomized controlled trial of a parent-mediated group intervention","authors":"Claudia S. Y. Ong,&nbsp;Jacqui Rodgers,&nbsp;Matthew N. Cooper,&nbsp;Zac Dempsey,&nbsp;Rebecca Eaton,&nbsp;Katia Haines,&nbsp;Rebecca Kuzminski,&nbsp;Iliana Magiati,&nbsp;Murray T. Maybery,&nbsp;Mirko Uljarević,&nbsp;John Wray,&nbsp;Andrew J. O. Whitehouse,&nbsp;Gail A. Alvares","doi":"10.1002/jcv2.70027","DOIUrl":"10.1002/jcv2.70027","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Background</h3>\u0000 \u0000 <p>Young children diagnosed with autism experience high rates of co-occurring anxiety, with uncertainty-related concerns commonly reported. This randomized controlled trial investigated an 8-week parent-mediated group anxiety intervention, “Coping with Uncertainty in Everyday Situations” (CUES-Junior©).</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Methods</h3>\u0000 \u0000 <p>Parents of 4–7-year-old children diagnosed with autism and experiencing uncertainty-related anxiety were recruited. The primary outcome was change from baseline in blinded assessor ratings of child responses to uncertainty and impact on family, measured post-intervention and 2-month follow-up. Secondary outcomes were parent-reported child anxiety and intolerance of uncertainty (IU), parental IU and mental health, parenting sense of competence, along with intervention feasibility and acceptability.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>Sixty-four children were randomized to CUES-Junior© (<i>n</i> = 33) or waitlist (<i>n</i> = 31); five families withdrew post-randomization. Immediately post-intervention, significantly more CUES-Junior© participants were rated as clinically improved from baseline in child responses to uncertainty (OR = 34.48; 95% CI = 1.72–690.04, <i>p</i> = 0.02) and in family impact (OR = 8.99; 95% CI = 1.52–53.05, <i>p</i> = 0.02) compared to waitlist. Significant improvements were also observed in parent-reported child IU and parenting satisfaction, favoring CUES-Junior©. At subsequent 2-month follow-up, CUES-Junior© participants showed sustained improvements in the impact of uncertainty on children, and parental ratings of child IU and anxiety, parenting sense of competence, and parental stress, compared to baseline. The program was feasible to administer and acceptable to parents.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusions</h3>\u0000 \u0000 <p>CUES-Junior© had an immediate treatment effect on child responses to uncertain situations and impact on families, with maintained improvements observed at follow-up. This novel mechanism-targeted and autism-informed program holds promise for addressing early uncertainty-related anxiety in young children diagnosed with autism.</p>\u0000 </section>\u0000 </div>","PeriodicalId":73542,"journal":{"name":"JCPP advances","volume":"6 1","pages":""},"PeriodicalIF":3.1,"publicationDate":"2026-03-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12973137/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147437597","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The impact of less severe intimate partner aggression on child conduct problems","authors":"Hedwig Eisenbarth,&nbsp;Karina Clavijo Saldias,&nbsp;Paul E. Jose,&nbsp;Johannes A. Karl,&nbsp;Karen E. Waldie","doi":"10.1002/jcv2.70024","DOIUrl":"10.1002/jcv2.70024","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Background</h3>\u0000 \u0000 <p>Significant intimate partner aggression (IPA) has been found to negatively impact outcomes of children, such as increased conduct problems (CP). However, it is unclear if forms of IPA that are less severe (e.g., shoving, pushing or yelling) have no, little, or substantial impact on child CP, which would indicate that the intensity (i.e., dosage) of IPA matters. In addition, it is unknown if the impact of IPA on child CP depends on the reporter (mother vs. partner) and on variables such as maternal depression and parenting.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Methods</h3>\u0000 \u0000 <p>We investigated the impact of IPA (both mother- and partner-reported), assessed during pregnancy and 9 months postpartum, on child CP at ages 2, 4.5, and 8 years. We also tested both the potential mediating role of maternal depression and moderating role of maternal warmth, reflecting risk and protective factors, respectively. Using longitudinal data from the Growing Up in New Zealand study, we tested path models with 5298 children.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>IPA predicted greater child CP for both mother- and partner-reported IPA, but at different age. Maternal depression partly mediated this effect, which was not moderated by maternal warmth.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusion</h3>\u0000 \u0000 <p>These findings underscore the importance of exposure to IPA on child development and provides evidence for that impact on behaviour independent of the effects of maternal depression. Positive parenting like maternal warmth seems not to buffer those negative effects.</p>\u0000 </section>\u0000 </div>","PeriodicalId":73542,"journal":{"name":"JCPP advances","volume":"6 1","pages":""},"PeriodicalIF":3.1,"publicationDate":"2026-03-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12973122/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147437785","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Guidance for umbrella reviews of observational studies: A scoping review","authors":"Carl Zhou,&nbsp;Nicholas Fabiano,&nbsp;Arnav Gupta,&nbsp;Stanley Wong,&nbsp;Kelly D. Cobey,&nbsp;David Moher,&nbsp;Sanam Ebrahimzadeh,&nbsp;Jeremy Y. Ng,&nbsp;Elena Dragioti,&nbsp;Jae Il Shin,&nbsp;Joaquim Radua,&nbsp;Samuele Cortese,&nbsp;Beverley Shea,&nbsp;Nicola Veronese,&nbsp;Lisa Hartling,&nbsp;Michelle Pollock,&nbsp;Stefania Papatheodorou,&nbsp;John P. A. Ioannidis,&nbsp;Marco Solmi","doi":"10.1002/jcv2.70017","DOIUrl":"10.1002/jcv2.70017","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Background</h3>\u0000 \u0000 <p>Umbrella reviews, or overviews of reviews, synthesize information using systematic reviews (SRs) as their unit of analysis. Although a formal guideline exists for reporting umbrella reviews of healthcare interventions (i.e. Preferred Reporting Items for Overviews of Reviews [PRIOR]), no formal guideline exists for conducting and/or reporting umbrella reviews of observational studies that examine epidemiological associations.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Objective</h3>\u0000 \u0000 <p>To review the existing guidance on conducting and/or reporting umbrella reviews of observational studies on epidemiological associations, as part of the process of developing a formal reporting guideline.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Methods</h3>\u0000 \u0000 <p>We reviewed the scoping review conducted in the context of PRIOR development and identified documents through forward citation search in PubMed, Scopus, and manual search in Google Scholar, Google Search up to December 22, 2024. Documents, regardless of format, were included if they provided guidance for conducting and/or reporting umbrella reviews of observational studies (including meta-research studies of their features). Title/abstract screening and data extraction were performed independently and in duplicate and summarized narratively by stages of the umbrella review process.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>The search retrieved 4491 unique records, with 96 full texts assessed and eight documents included. These documents, published between 2014 and 2023, offered guidance across seven topic areas, but overall guidance on conducting and/or reporting is limited. These areas include the answerable questions, prerequisite considerations, the scope of umbrella reviews, searching for SRs, primary data collection, analysis, presentation, and assessing the certainty/quality of the body of evidence.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusion</h3>\u0000 \u0000 <p>There is a need for dedicated, practical, and evidence-based formal reporting guidelines for umbrella reviews of observational studies on epidemiological associations. This review lays the groundwork for developing the PRIOR-extension for such studies: the Preferred Reporting Items for Umbrella Reviews of Cross-sectional, Case-control, and Cohort Studies.</p>\u0000 </section>\u0000 </div>","PeriodicalId":73542,"journal":{"name":"JCPP advances","volume":"6 1","pages":""},"PeriodicalIF":3.1,"publicationDate":"2026-03-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12973145/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147438164","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Why do attention-deficit/hyperactive disorder and/or autism traits place adolescents at risk for depression? Protocol for a longitudinal comparison of the mediating role of emotion regulation deficits versus emotional burden","authors":"Edmund J. S. Sonuga-Barke,&nbsp;Melanie Palmer,&nbsp;Kirsty Griffiths,&nbsp;Anna Wyatt,&nbsp;Andrea Danese,&nbsp;Susie Chandler,&nbsp;Daniel Stahl,&nbsp;Steve Lukito,&nbsp;Georgia Pavlopoulou,&nbsp;Emily Simonoff,&nbsp;the RE-STAR team","doi":"10.1002/jcv2.70052","DOIUrl":"10.1002/jcv2.70052","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Background</h3>\u0000 \u0000 <p>Depression levels increase dramatically during adolescence in the general population. This effect is exacerbated in adolescents with a diagnosis of attention-deficit/hyperactivity disorder (ADHD), autism, or both. Here we detail the protocol for the <i>My Emotions and Me Over Time</i> (MEMO) study, a 12-month longitudinal study with the primary aim to compare two competing hypotheses for why this is the case. The first, established hypothesis is that depression risk associated with ADHD and/or autism is mediated by emotion regulation deficits (ERD). The second and new perspective is that it is mediated by the experience of elevated <i>emotional burden</i> (EB) created by (i) greater exposure to upsetting events and encounters, which are (ii) experienced more intensely. Cross-lagged path models will test the relative importance of the ERD and EB pathways to the relationship between autism and ADHD traits and depression symptoms. Exploratory analyses examining secondary mediators (i.e., self-esteem) and moderators (rumination, resilience and alexithymia) will also be conducted.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Methods</h3>\u0000 \u0000 <p>A sample of 600 adolescents aged 11–16 years, enriched for the presence of autism and ADHD diagnosed cases, and their parent/guardian will be recruited via schools, local NHS (South London and Maudsley) and ADHD and autism charities. Measures of ADHD, autism and depression, ERD, EB, self-esteem, rumination, resilience and alexithymia will be completed at baseline, 6 months and/or 12 months by parents and/or participants. Background factors such as age, sex, cognitive abilities and socioeconomic status as well as service use and medication status will also be collected.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>The pathways between ADHD/autism and depression, along with their mediators and moderators, will be analysed using structural equation modelling.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusion</h3>\u0000 \u0000 <p>The findings from MEMO will feed into the other studies within the RE-STAR programme to support the development of an intervention to reduce ADHD and/or autism-related depression risk in adolescence.</p>\u0000 </section>\u0000 </div>","PeriodicalId":73542,"journal":{"name":"JCPP advances","volume":"6 1","pages":""},"PeriodicalIF":3.1,"publicationDate":"2026-03-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12973166/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147437745","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}