JADA foundational science最新文献

{"title":"Exploratory investigation of quantitative percussion diagnostics in endodontic health and pathology","authors":"Jie Shen PhD ,&nbsp;Clifford J. Ruddle DDS ,&nbsp;John West DDS, MSD ,&nbsp;Cherilyn G. Sheets DDS ,&nbsp;James C. Earthman PhD","doi":"10.1016/j.jfscie.2025.100060","DOIUrl":"10.1016/j.jfscie.2025.100060","url":null,"abstract":"<div><h3>Background</h3><div>Quantitative percussion diagnostics (QPD) have been able to detect coronal microgap defects (MGDs) at early stages. Specifically, QPD identified early MGDs associated with restorative luting failures, coronal and radicular root fractures, and implants. Another potential MGD for teeth is a defective periodontal ligament (PDL). If there is early attachment apparatus disease, there is a high probability that the PDL is damaged. This study investigated the QPD response of a tooth with a lesion of endodontic origin (LEO) to determine if the damaged PDL can be detected.</div></div><div><h3>Methods</h3><div>An in vivo tooth with a periapical LEO was clinically evaluated by using radiographs, cone-beam computed tomographic images, and QPD. Finite element analysis (FEA) was used to accurately model this same tooth to simulate the apical LEO in the model. Reduced moduli in tissue components were used to simulate the effect of the LEO. The clinical QPD result was validated using FEA for an endodontically failing mandibular first molar with an apical LEO.</div></div><div><h3>Results</h3><div>The in vitro FEA results show consistent features with the corresponding clinical QPD results and validate that the model closely replicates the tooth and the LEO observed with radiographic and cone-beam computed tomographic images. It was also shown that these FEA results and clinical QPD results yield nearly the same normal fit error values.</div></div><div><h3>Conclusions</h3><div>The agreement between this in vitro FEA model and the in vivo clinical QPD results for a mandibular molar with an apical LEO indicates that QPD can detect a damaged PDL.</div></div>","PeriodicalId":73530,"journal":{"name":"JADA foundational science","volume":"5 ","pages":"Article 100060"},"PeriodicalIF":0.0,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145798028","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Pomelo essential oil","authors":"Hoai Thu Le PhD ,&nbsp;Thanh-Hoa Vo PhD ,&nbsp;Phuoc-Vinh Nguyen PhD ,&nbsp;Gia Phong Vu PhD ,&nbsp;Bac V.G. Nguyen PhD","doi":"10.1016/j.jfscie.2025.100066","DOIUrl":"10.1016/j.jfscie.2025.100066","url":null,"abstract":"<div><h3>Background</h3><div><em>Streptococcus mutans</em> and <em>Candida albicans</em> are key contributors to oral diseases because of their strong ability to form resilient biofilms on dental material surfaces. These biofilms pose significant challenges for infection control and treatment. Natural essential oils, known for their antimicrobial properties, have emerged as promising alternatives to conventional chemical agents.</div></div><div><h3>Methods</h3><div>This study evaluated the antimicrobial and antibiofilm effects of pomelo essential oil on 3 types of dental materials: acrylic, composite resin, and the bis-acrylic compound Tempofit (DETAX GmbH &amp; Co KG). The essential oil was applied at various concentrations to both preformed biofilms and as a pretreatment before microbial exposure. Cytotoxicity was assessed using HEK293T cells to determine safety.</div></div><div><h3>Results</h3><div>Pomelo essential oil exhibited dose- and time-dependent biofilm eradication across all tested materials. It significantly reduced microbial viability in established biofilms and effectively inhibited biofilm formation when applied as a pretreatment. Cytotoxicity analysis revealed a median lethal dose of 0.03658%, indicating low toxicity to human cells.</div></div><div><h3>Conclusions</h3><div>The findings showed that pomelo essential oil is a safe and effective natural agent for disrupting and preventing biofilm formation on dental materials. Its potential application in commercial oral care products may offer a safer alternative for managing biofilm-associated infections in clinical settings.</div></div>","PeriodicalId":73530,"journal":{"name":"JADA foundational science","volume":"5 ","pages":"Article 100066"},"PeriodicalIF":0.0,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147395473","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Cone-beam computed tomographic evaluation of bone engagement in 2 orientations of pterygoid implant placement","authors":"Tu Lam Doan DDS, MSc ,&nbsp;Cam Le Ngoc Hong DDS, MSc ,&nbsp;Thao Ngoc Phuong Tran DDS, PhD ,&nbsp;Lam Nguyen Le DDS, PhD ,&nbsp;Thuy Anh Vu Pham DDS, PhD","doi":"10.1016/j.jfscie.2026.100071","DOIUrl":"10.1016/j.jfscie.2026.100071","url":null,"abstract":"<div><h3>Background</h3><div>Pterygoid implants can be placed in different orientations. This study compared 2 distinct implant trajectories in terms of bone engagement and implant characteristics.</div></div><div><h3>Methods</h3><div>Dedicated planning software was used to review cone-beam computed tomography data sets and to position virtual implants within the pterygomaxillary complex. The following measurements were made on cross-sectional, panoramic, and modified buccopalatal reconstructions: the total bone length along the implant axis, the length of bone engagement, anteroposterior and buccopalatal angulations, and the mesiodistal position of the osteotomy.</div></div><div><h3>Results</h3><div>A total of 169 pterygoid regions with 169 implants per implant-trajectory group were included in this study. The high-trajectory group exhibited a mean (SD) total osseous length of 19.9 (3.2) mm, significantly greater than the 17.9 (3.3) mm recorded for the low-trajectory group (<em>P</em> &lt; .001). The pterygoid-process penetration (SD) was also greater in the high-trajectory group (8.7 [2.8] mm) than in the low-trajectory group (5.8 [2.3] mm; <em>P</em> &lt; .001). With respect to the virtual implant length, the high-trajectory group required a longer fixture than the low-trajectory group (mean difference, −2.0 mm; <em>P</em> &lt; .001). The linear mixed-effects model was used to compare all parameters.</div></div><div><h3>Conclusions</h3><div>High-direction pterygoid implant placement achieves deeper purchase within the dense pterygomaxillary complex and therefore offers superior virtual bone engagement. Across both orientations, an implant length of 16 through 20 mm is selected most frequently.</div></div>","PeriodicalId":73530,"journal":{"name":"JADA foundational science","volume":"5 ","pages":"Article 100071"},"PeriodicalIF":0.0,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147395481","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Surface enamel microhardness in nonclinical anticaries testing of fluoride toothpaste","authors":"Masoumah Qaw BDS, MSD ,&nbsp;Tasneem Alluhaidan BDS, MSc ,&nbsp;Katherine M. Mann PhD ,&nbsp;Hana Mujahid PhD ,&nbsp;Mary Anne S. Melo DDS, MS, PhD","doi":"10.1016/j.jfscie.2025.100069","DOIUrl":"10.1016/j.jfscie.2025.100069","url":null,"abstract":"<div><h3>Background</h3><div>This scoping review systematically evaluates the methodologies used in assessing enamel surface microhardness (SMH) in demineralization and remineralization research of anticaries toothpastes. The review identifies the parameters influencing SMH testing, highlights methodological variations, and proposes recommendations to standardize protocols and enhance reliability and suitability.</div></div><div><h3>Search Strategy</h3><div>The review followed Arksey and O’Malley’s framework, using comprehensive database searches.</div></div><div><h3>Citation Sources</h3><div>Sources include MEDLINE, Embase, and Scopus.</div></div><div><h3>Study Selection Criteria</h3><div>In vitro and in situ studies evaluating the SMH of human enamel using fluoride toothpaste were included.</div></div><div><h3>Data Elements Included</h3><div>Evidence quality was assessed, and data extraction focused on testing parameters, sample characteristics, and methodological rigor. A total of 16,193 studies were screened, and 53 were included for full-text analysis. Remarkable methodological heterogeneity was observed. Only 21% of studies reported sample size calculations, and 17% used blinding. Screening methods for defects were inconsistent. Variations in SMH testing parameters were also notable. The Vickers indenter was the most commonly used. Loading forces varied widely, ranging from 25 through 500 g, with 50 g being the most applied. Most studies used a dwell time of 10 through 20 seconds. Variability in sample geometry and preparation techniques was identified, which can influence SMH values. Limited studies reported quality criteria such as statistical differences between groups (8%), underscoring the variability in reporting standards.</div></div><div><h3>Overall Conclusions</h3><div>The findings reveal substantial gaps in methodological rigor and consistency across studies, emphasizing the need for standardized protocols in enamel SMH testing. This review provides insights for future research to validate alternative anticaries testing procedures applicable to regulatory testing or other standardized clinical testing.</div></div>","PeriodicalId":73530,"journal":{"name":"JADA foundational science","volume":"5 ","pages":"Article 100069"},"PeriodicalIF":0.0,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147395475","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Influence of silica nanoparticle concentration on 3-dimensional–printed resin-based composite","authors":"Francisco Amaro Morganti DDS, MSc ,&nbsp;Ana Cristina Andriolli Zattera DDS ,&nbsp;Gabriela de Souza Balbinot DDS, MSc, PhD ,&nbsp;Alvaro Della Bona DDS, MMedSci, PhD, FADM ,&nbsp;Fabricio Mezzomo Collares DDS, MSc, PhD","doi":"10.1016/j.jfscie.2025.100059","DOIUrl":"10.1016/j.jfscie.2025.100059","url":null,"abstract":"<div><h3>Background</h3><div>Nanoparticle load may interfere with the viscosity of the composites, challenging the printability in vat-polymerization techniques. This study aimed to evaluate the influence of silica nanoparticle addition on the physicochemical properties of a 3-dimensional (3D)-printed resin-based composite (RBC).</div></div><div><h3>Methods</h3><div>The resinous matrix of the experimental 3D RBC was kept fixed with the addition of silica nanoparticles (Aerosil OX50; Evonik), which were surface-treated with 3-(trimethoxysilyl) propyl methacrylate and used as fillers at 5 wt% (silicon dioxide [SiO₂] 5%), 10 wt% (SiO₂10%), and 20 wt% (SiO₂20%). The composite’s viscosity was evaluated before printing. Specimens were 3D printed (Anycubic Photon Mono 4K 3D Printer; Anycubic Inc), cleaned with 96% ethanol, and postcured (Form Cure; Formlabs) at 60 °C. Specimens were evaluated for their radiopacity, polymerization kinetics, and degree of conversion. The flexural strength was assessed after 24 hours and 14 days of water storage.</div></div><div><h3>Results</h3><div>Silica nanoparticles were a median size of 65 nm (d₁₀: 35 nm; d₉₀: 129 nm). The addition of silica nanoparticles resulted in a 2-fold increase in the resin viscosity, without modifying the specimens’ radiopacity. All groups presented more than 80% degree of conversion, but a faster polymerization with higher polymerization rates was observed for the SiO₂5%. Despite the increased immediate flexural strength (mean [SD], 81.78 [3.14] MPa) shown by SiO₂20%, the strength was reduced for all experimental groups after 14 days in water.</div></div><div><h3>Conclusions</h3><div>Increasing concentrations of silica nanoparticles increased 3D RBC properties. However, after 14 days of water storage, decreased flexural strength was observed.</div></div>","PeriodicalId":73530,"journal":{"name":"JADA foundational science","volume":"5 ","pages":"Article 100059"},"PeriodicalIF":0.0,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145798029","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effect of incorporating chitosan and propolis in dentifrices on the permeability and roughness of root dentin","authors":"Paloma Eduarda Alberti DDS ,&nbsp;Camila Scaff Neves Monteiro DDS ,&nbsp;Letícia de Sousa Franco DDS, MSc ,&nbsp;Laura Nobre Ferraz DDS, MSc, PhD ,&nbsp;Fernanda Flores Navarro DDS, MSc, PhD ,&nbsp;Marcos Roberto Lima Benati DDS, MSc ,&nbsp;Silmara Aparecida Milori Corona DDS, MSc, PhD ,&nbsp;Renata Siqueira Scatolin DDS, MSc, PhD","doi":"10.1016/j.jfscie.2025.100068","DOIUrl":"10.1016/j.jfscie.2025.100068","url":null,"abstract":"<div><h3>Background</h3><div>This study investigated in vitro the effects of experimental dentifrices containing chitosan and propolis on the permeability and roughness of root dentin.</div></div><div><h3>Methods</h3><div>Sixty cylindrical bovine dentin samples were divided into 4 groups: base dentifrice (BD), BD and propolis (DP), BD and chitosan (DC), and BD, chitosan, and propolis (DCP). The samples underwent erosion cycles (4 times daily with 0.3% citric acid) and brushing (2 times daily, 2 minutes each). Permeability and roughness were assessed at 2 times: postexposure of dentinal tubules and posttreatment with dentifrice and erosive challenges. Scanning electron microscopy (SEM) was performed qualitatively after treatment and erosive challenges at ×2,000 magnification.</div></div><div><h3>Results</h3><div>All groups exhibited reduced dentin permeability, with the DCP group showing the most significant reduction compared with the BD or DP groups (<em>P</em> &lt; .05). No significant differences in roughness were observed between the BD and DC or DP. SEM revealed that none of the tested dentifrices fully occluded dentinal tubules; however, the chitosan-containing groups showed a higher number of particles within the tubules.</div></div><div><h3>Conclusions</h3><div>The combination of chitosan and propolis in a dentifrice effectively reduced dentin permeability without significantly affecting surface roughness.</div></div>","PeriodicalId":73530,"journal":{"name":"JADA foundational science","volume":"5 ","pages":"Article 100068"},"PeriodicalIF":0.0,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145976585","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effect of experimental dentifrices containing epigallocatechin-3-gallate–loaded chitosan nanoparticles on permeability, tubule occlusion, microhardness, and wear in eroded dentin","authors":"Karen Pintado-Palomino DDS, MSc, PhD ,&nbsp;Letícia de Sousa Franco DDS, MSc ,&nbsp;Renata Siqueira Scatolin DDS, MSc, PhD ,&nbsp;Luiza Araújo Gusmão MSc, PhD ,&nbsp;Antonio Claudio Tedesco MSc, PhD ,&nbsp;Mario Sadaiti Ogasawara ,&nbsp;Raissa Manoel Garcia DDS, MSc ,&nbsp;Tais Scaramucci DDS, PhD ,&nbsp;Silmara Aparecida Corona DDS, MSc, PhD","doi":"10.1016/j.jfscie.2025.100057","DOIUrl":"10.1016/j.jfscie.2025.100057","url":null,"abstract":"<div><h3>Background</h3><div>Dentin hypersensitivity and tooth wear are common oral conditions. Natural substances and nanotechnology emerge as promising approaches. This study aimed to evaluate the effect of experimental dentifrices containing epigallocatechin-3-gallate (EGCG)–loaded chitosan nanoparticles (NChi) on permeability (Lp), tubule occlusion, microhardness, and wear in dentin under erosive challenge.</div></div><div><h3>Methods</h3><div>This in situ study included 5 phases (5 days each) and a washout period (7 days). Eight participants wore intraoral mandibular devices containing 2 bovine dentin samples on each side with tubule exposure (time [T]1). The samples were eroded extraorally (0.3% citric acid, pH = 2.6, 4 times per day) and intraorally brushed with dentifrices (15 seconds, 2 times per day) for 5 days (T2), according to the following groups: placebo (PL), NChi, EGCG encapsulated in chitosan (NChi and EGCG), EGCG, and Elmex Sensitive (ES) (GABA). Lp, open dentin tubules, surface microhardness (SMH), surface loss, and scanning electron microscopy results were assessed.</div></div><div><h3>Results</h3><div>All groups showed significant differences in Lp between T1 and T2 (<em>P</em> &lt; .05), and PL was different from the other groups at T2 (<em>P</em> &lt; .05). For both open dentin tubules and SMH, all groups except PL showed statistical differences between T1 and T2 (<em>P</em> &lt; .05). At T2, NChi and EGCG, EGCG, and ES showed higher SMH than PL (<em>P</em> &lt; .05). There was no statistically significant difference among the groups in terms of the surface loss (<em>P</em> = .29).</div></div><div><h3>Conclusions</h3><div>Dentifrices containing an active composition (NChi, NChi and EGCG, EGCG, ES) were effective in promoting tubule occlusion and increasing microhardness, with comparable efficacy. All the dentifrices showed similar wear on the dentin surface.</div></div>","PeriodicalId":73530,"journal":{"name":"JADA foundational science","volume":"5 ","pages":"Article 100057"},"PeriodicalIF":0.0,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145694387","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Influence of metal-ceramic crown preparation geometry on adhesive stress during orthodontic headgear force application","authors":"Afrooz Rafiee DDS ,&nbsp;Ahmadreza Sardarian MSc ,&nbsp;Allahyar Geramy MSc ,&nbsp;Elham Ansarifard MSc","doi":"10.1016/j.jfscie.2025.100058","DOIUrl":"10.1016/j.jfscie.2025.100058","url":null,"abstract":"<div><h3>Background</h3><div>This study used finite element analysis to assess how crown preparation height (short, normal, long) and tapering (6°-24°) affect prosthetic crown retention under orthodontic and biting forces, measured by von Mises stress in the cement layer.</div></div><div><h3>Methods</h3><div>Models with 3 occlusocervical heights and tapering from 6° through 24° were subjected to orthodontic loads (2, 5, 10 N) and simulated bite forces (vertical or oblique 280 N).</div></div><div><h3>Results</h3><div>Under orthodontic loads, the long crown with 6° tapering showed the least stress at lower forces; a 12° taper was best at 10 N. The short crown with 6° taper consistently had the highest stress. Under vertical bite force, the long crown with 6° tapering had the least stress, whereas the normal crown with 24° tapering had the most. Under oblique bite force, the normal crown with 12° tapering had the least stress, and the long crown with 24° tapering had the most. Stress under orthodontic loads showed no consistent correlation with height or taper but increased with greater tapering under bite force.</div></div><div><h3>Conclusions</h3><div>Optimal crown design depends on force type. Long crowns performed best under vertical bite forces but worst under oblique forces. Normal crowns showed the opposite pattern. Stress distribution varies with loading conditions.</div></div>","PeriodicalId":73530,"journal":{"name":"JADA foundational science","volume":"5 ","pages":"Article 100058"},"PeriodicalIF":0.0,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145651949","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Antimicrobial activity and biocompatibility of chitosan-coated orthodontic miniscrews","authors":"Karima Qurnia Mansjur DDS, PhD ,&nbsp;Eka Erwansyah DDS ,&nbsp;Ardiansyah S. Pawinru DDS ,&nbsp;Dian Yosi Arinawati DDS, PhD ,&nbsp;Widyasri Prananingrum DDS, PhD ,&nbsp;Islamy Rahma Hutami DDS, PhD ,&nbsp;Od Bayarsaikhan DDS, PhD ,&nbsp;Asma Ashari DDS, PhD ,&nbsp;Eiji Tanaka DDS, PhD","doi":"10.1016/j.jfscie.2026.100073","DOIUrl":"10.1016/j.jfscie.2026.100073","url":null,"abstract":"<div><h3>Background</h3><div>Peri-implantitis caused by bacterial colonization is a primary factor in orthodontic miniscrew failure. This study evaluated the antibacterial activity, biocompatibility, and surface characteristics of <em>Loligo</em>-derived chitosan coatings on orthodontic miniscrews.</div></div><div><h3>Methods</h3><div>Chitosan was extracted and applied to miniscrews using a dip-coating method. Surface morphology and elemental composition were assessed using Fourier-transform infrared spectroscopy, scanning electron microscopy, and energy-dispersive x-ray spectroscopy. The antibacterial activity against <em>Streptococcus mutans</em> was evaluated through inhibition zone, minimum inhibitory concentration, and minimum bacterial concentration tests. Cytotoxicity was tested on NIH/3T3 fibroblasts. Molecular docking was used to analyze the interactions of glucosamine with <em>S mutans</em> glucansucrase and FimA proteins.</div></div><div><h3>Results</h3><div>Fourier-transform infrared spectroscopy confirmed functional groups characteristic of chitosan. Scanning electron microscopy revealed a rough and porous surface after coating, whereas energy-dispersive x-ray spectroscopy revealed increased carbon and oxygen content. Coated miniscrews showed significantly greater inhibition zones and lower minimum inhibitory concentration and minimum bacterial concentration values than uncoated screws, with no significant cytotoxicity. Docking analysis indicated strong binding of glucosamine to glucansucrase (−4.9 kcal/mol) and moderate binding to FimA (−3.1 kcal/mol).</div></div><div><h3>Conclusions</h3><div><em>Loligo</em>-derived chitosan coatings enhance the antibacterial properties of orthodontic miniscrews while maintaining biocompatibility, offering a potential and sustainable strategy for reducing the risk of peri-implantitis.</div></div>","PeriodicalId":73530,"journal":{"name":"JADA foundational science","volume":"5 ","pages":"Article 100073"},"PeriodicalIF":0.0,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147709427","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Mechanical and chemical properties of a 3-dimension–printed denture base resin obtained by varying digital light processing and liquid crystal display printing angles","authors":"Hamile Emanuella do Carmo Viotto DDS, MSc ,&nbsp;João Fernando Carrijo Queiroz DDS, MSc ,&nbsp;Larianne de Sousa Moisés DDS ,&nbsp;Sabrina Romão Gonçalves Coelho DDS ,&nbsp;Guilherme Thummel Berguelli Piza ,&nbsp;João Antonio Oliveira Santos PhD ,&nbsp;Ana Carolina Pero DDS, PhD","doi":"10.1016/j.jfscie.2025.100064","DOIUrl":"10.1016/j.jfscie.2025.100064","url":null,"abstract":"<div><h3>Background</h3><div>The authors evaluate the effect of different printing technologies (digital light processing [DLP], liquid crystal display [LCD]), and different printing angles (0°, 45°, 90°) on the mechanical (flexural strength [FS] and Vickers hardness number [VHN]) and chemical properties (degree of conversion [DC], surface microstructural, and glass transition temperature [Tg]) of a 3-dimension–printed denture base resin.</div></div><div><h3>Methods</h3><div>Three-dimension–printed specimens (priZma 3D Bio Denture; MakertechLabs) were grouped: LCD0°, LCD45, LCD90°, DLP0°, DLP45°, and DLP90°. Thirty specimens were fabricated per group, for FS (12), VHN (12), DC (2), x-ray excited photoelectron spectroscopy (2), and Tg (2).</div></div><div><h3>Results</h3><div>For FS (MPa), a significant difference (SD) was found between DLP (93 [15]) and LCD (82 [14]) (2-way analysis of variance, <em>P</em> &lt; .001), and 0° (79 ± 9), 45° (99 ± 12), and 90° (84 [16]) (Tukey test, <em>P</em> &lt; .05). For VHN, no significant effects were detected (2-way analysis of variance, <em>P</em> &gt;.05). Tg ranged from 80 °C through 100 °C for all groups. The highest means (SD) of DC were achieved for the specimens printed at 0° (DLP, 86.8 [3.7]%; LCD, 89.6 [0.3]%).</div></div><div><h3>Conclusions</h3><div>The DLP system and 45° presented the highest FS, whereas the printing angle of 0° exhibited the highest DC. Considering that both systems (DLP, LCD) showed results above the threshold of 65 MPa for FS of denture base materials, and that LCD is a faster and lower-cost system, this technology could also be suggested for printing denture bases.</div></div>","PeriodicalId":73530,"journal":{"name":"JADA foundational science","volume":"5 ","pages":"Article 100064"},"PeriodicalIF":0.0,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145797947","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}