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Independent and Interactive Impacts of Prenatal Exposure to Legal Substances and Childhood Trauma on Emotion Processing in Pre-Adolescents: Preliminary Findings From the ABCD Study 产前接触合法药物和童年创伤对青春期前青少年情绪处理的独立和交互影响:ABCD 研究的初步发现
JAACAP open Pub Date : 2024-12-01 DOI: 10.1016/j.jaacop.2024.04.009
Lauren Lepow MD , Ariella Wagner MS , Siddhartha Peri BS , Faith Adams BS , Srinivasan Anantha Ramakrishnan BS , Md Ashad Alam PhD , Riaz B. Shaik PhD , Nicholas A. Hubbard PhD , Harold W. Koenigsberg MD , Yasmin Hurd PhD , Susan F. Tapert PhD , Iliyan Ivanov MD , Muhammad A. Parvaz PhD
{"title":"Independent and Interactive Impacts of Prenatal Exposure to Legal Substances and Childhood Trauma on Emotion Processing in Pre-Adolescents: Preliminary Findings From the ABCD Study","authors":"Lauren Lepow MD , Ariella Wagner MS , Siddhartha Peri BS , Faith Adams BS , Srinivasan Anantha Ramakrishnan BS , Md Ashad Alam PhD , Riaz B. Shaik PhD , Nicholas A. Hubbard PhD , Harold W. Koenigsberg MD , Yasmin Hurd PhD , Susan F. Tapert PhD , Iliyan Ivanov MD , Muhammad A. Parvaz PhD","doi":"10.1016/j.jaacop.2024.04.009","DOIUrl":"10.1016/j.jaacop.2024.04.009","url":null,"abstract":"<div><h3>Objective</h3><div>This paper investigated the effects of prenatal drug exposure (PDE), childhood trauma (CT), and their interactions on the neurobiological markers for emotion processing.</div></div><div><h3>Method</h3><div>Here, in a non-clinical sample of pre-adolescents (9-10 years of age) from the Adolescent Brain Cognitive Development (ABCD) Study (N = 6,146), we investigate the impact of PDE to commonly used substances (ie, alcohol, cigarettes, and marijuana), CT, and their interaction on emotion processing. From the Emotional N-back functional magnetic resonance imaging task data, we selected 26 regions of interests, previously implicated in emotion processing, and conducted separate linear mixed models (108 total) and accounted for available environmental risk factors.</div></div><div><h3>Results</h3><div>PDE was associated with reductions in response bias related to the processing of fearful compared to happy faces in widespread cortical regions (including the superior frontal and fusiform gyri and the inferior parietal lobule). Reduced response bias in the superior frontal gyrus emerged as PDE driven and was present regardless of CT status, but correlated with several items on the Child Behavior Checklist only in those children with both PDE and CT. The lower response bias of the left inferior parietal lobule, on the other hand, was observed only in children with both PDE and CT, and correlated with internalizing and externalizing behaviors.</div></div><div><h3>Conclusion</h3><div>The study’s results support the diathesis–stress model, and suggest that PDE may confer vulnerability to the effects of later CT through altered neurodevelopment. Children experiencing these “double-hit” conditions may represent at-risk individuals who could benefit from early interventions to mitigate the onset of psychopathology. Because of limitations in the way that PDE was reported in the ABCD Study, including lack of severity measures and retrospective reporting, results are not sufficient for making recommendations or dictating policy for pregnant persons. Nevertheless, this study is a necessary first step in examining the interactive effects of prenatal and early-life exposures, as well as many aspects of the sociodemographic and psychological environment.</div></div><div><h3>Plain language summary</h3><div>This study looked at how prenatal drug exposure of commonly used substances (alcohol, cigarettes, and cannabis) and childhood trauma affect brain activity related to processing emotions in children from the Adolescent Brain Cognitive Development (ABCD) Study. Using brain imaging data from 6,146 children aged 9-10, the study found that prenatal drug exposure was associated with differing brain activity to emotional faces in several brain regions involved in emotion processing. Children who experienced both prenatal drug exposure and childhood trauma showed altered brain activity patterns that correlated with greater behavioral problems repo","PeriodicalId":73525,"journal":{"name":"JAACAP open","volume":"2 4","pages":"Pages 274-289"},"PeriodicalIF":0.0,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141706598","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Combining Motivational Interviewing and Cognitive Bias Modification Training for Substances in Detained Youth 动机性访谈与认知偏差矫正训练相结合的青少年吸毒行为研究。
JAACAP open Pub Date : 2024-12-01 DOI: 10.1016/j.jaacop.2024.08.003
Hans S. van der Baan PhD , Annematt L. Collot D'Escury-Koenigs PhD , Raoul P.P.P. Grasman PhD , Gerard M. Schippers PhD , Reinout W. Wiers PhD
{"title":"Combining Motivational Interviewing and Cognitive Bias Modification Training for Substances in Detained Youth","authors":"Hans S. van der Baan PhD ,&nbsp;Annematt L. Collot D'Escury-Koenigs PhD ,&nbsp;Raoul P.P.P. Grasman PhD ,&nbsp;Gerard M. Schippers PhD ,&nbsp;Reinout W. Wiers PhD","doi":"10.1016/j.jaacop.2024.08.003","DOIUrl":"10.1016/j.jaacop.2024.08.003","url":null,"abstract":"<div><h3>Objective</h3><div>Motivation is considered a key factor in successful treatment. Unfortunately, detained youth typically show lower motivation for treatment and behavioral change. This pilot study examined the effects of a brief Motivational Interviewing (MI) protocol in conjunction with a Cognitive Bias Modification (CBM) intervention aimed at reducing substance use in detained youth.</div></div><div><h3>Method</h3><div>An MI protocol for adult parolees was adapted for adolescents. A total of 52 detained youth received the MI intervention, aimed at enhancing their insights into their substance use and its potential relation with their offenses, plus substance use treatment. These youth were matched with controls from similar populations who received the same CBM without MI.</div></div><div><h3>Results</h3><div>Changes in motivation over time were examined with a repeated-measures analysis of variance. Results showed no change in motivation over time, nor a significant effect of condition (MI vs no MI).</div></div><div><h3>Conclusion</h3><div>Although application of the MI protocol was feasible, no effect was found on motivation, in contrast to the original adult-focused protocol. Certain core facets of the original protocol, such as client reflection on their history of substance use, may be less applicable to detained youth whose use history is relatively brief. The severity of their substance use behavior should also be taken into account in any future applications.</div></div><div><h3>Plain language summary</h3><div>Motivational interviewing (MI) is an evidence-based method to increase behavioral change and treatment engagement. In this study, 52 detained youth received a 6 session MI protocol in addition to a cognitive bias modification (CBM) intervention targeting substance use, and they were matched with controls from a prior study where youth received CBM only. Neither group showed a change in motivation. These findings suggest that future MI-based interventions should consider the needs and developmental stages of youths with substance use.</div></div>","PeriodicalId":73525,"journal":{"name":"JAACAP open","volume":"2 4","pages":"Pages 301-310"},"PeriodicalIF":0.0,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11650685/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142855865","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Longitudinal Pathways From Maltreatment to Substance Use Through Delay Discounting During Adolescence and Into Young Adulthood 通过青春期和青年期的延迟折扣,从虐待到物质使用的纵向途径。
JAACAP open Pub Date : 2024-12-01 DOI: 10.1016/j.jaacop.2024.02.003
Kristin M. Peviani PhD , Claudia Clinchard MS , Warren K. Bickel PhD , Brooks Casas PhD , Jungmeen Kim-Spoon PhD
{"title":"Longitudinal Pathways From Maltreatment to Substance Use Through Delay Discounting During Adolescence and Into Young Adulthood","authors":"Kristin M. Peviani PhD ,&nbsp;Claudia Clinchard MS ,&nbsp;Warren K. Bickel PhD ,&nbsp;Brooks Casas PhD ,&nbsp;Jungmeen Kim-Spoon PhD","doi":"10.1016/j.jaacop.2024.02.003","DOIUrl":"10.1016/j.jaacop.2024.02.003","url":null,"abstract":"<div><h3>Objective</h3><div>Children and adolescents exposed to maltreatment are at a greater risk for substance use disorders in adulthood. However, developmental processes that explain how maltreatment experiences may influence substance use behaviors remain unclear. We investigated whether delay discounting (ie, the preference for immediate over delayed rewards), a critical indicator of self-regulation, serves as a key mechanism linking maltreatment and substance use. We used a developmental cascade model with a dimensional approach to test the direct and indirect effects of neglect and abuse on substance use during adolescence and across the transition from adolescence to young adulthood.</div></div><div><h3>Method</h3><div>The present study includes 167 adolescents (53% male; mean age = 14 years at time 1) who provided data on delay discounting and cigarette, alcohol, and cannabis use frequency across 5 time points (ages 14-18, approximately 1 year between assessments). At ages 18 to 19, adolescents provided reports of their exposure to maltreatment during adolescence (across ages 13-17).</div></div><div><h3>Results</h3><div>Using structural equation modeling, developmental cascade models tested whether the effects of neglect and abuse on cigarette, alcohol, and cannabis use were mediated through delay discounting over time. Our results indicate that adolescents exposed to neglect may be especially vulnerable to cannabis use over time via elevated delay discounting. Neglect experiences predicted greater cigarette use over time.</div></div><div><h3>Conclusion</h3><div>These findings underscore the critical role of delay discounting in prevention and intervention efforts aimed at mitigating the risks of substance use development among young people who have been exposed to neglect during adolescence.</div></div><div><h3>Plain language summary</h3><div>This study used a developmental cascade model to examine whether delay discounting (ie, choosing smaller, immediate rewards over larger rewards with a delay) may be a mechanism linking maltreatment and substance use (cigarette, alcohol, and cannabis use) during adolescence. One hundred sixty-seven adolescents aged 13-14 were assessed in a computerized delay discounting task across 5 time points over 6 years. Results indicated that adolescent neglect was associated with higher delay discounting, which in turn was associated with increased substance use, especially cannabis use. These findings highlight delay discounting as a potential intervention target to mitigate substance use risk in adolescents who have experienced neglect.</div></div>","PeriodicalId":73525,"journal":{"name":"JAACAP open","volume":"2 4","pages":"Pages 239-249"},"PeriodicalIF":0.0,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11650661/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142856758","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Introduction to a Special Series on Substance Use Disorder 关于物质使用障碍的特别系列简介。
JAACAP open Pub Date : 2024-12-01 DOI: 10.1016/j.jaacop.2024.10.004
Kara S. Bagot MD (Deputy Editor)
{"title":"Introduction to a Special Series on Substance Use Disorder","authors":"Kara S. Bagot MD (Deputy Editor)","doi":"10.1016/j.jaacop.2024.10.004","DOIUrl":"10.1016/j.jaacop.2024.10.004","url":null,"abstract":"","PeriodicalId":73525,"journal":{"name":"JAACAP open","volume":"2 4","pages":"Pages 229-230"},"PeriodicalIF":0.0,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11650689/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142856023","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Transparency: Disclosure of Financial Interests 透明度:披露财务利益。
JAACAP open Pub Date : 2024-12-01 DOI: 10.1016/j.jaacop.2024.10.003
{"title":"Transparency: Disclosure of Financial Interests","authors":"","doi":"10.1016/j.jaacop.2024.10.003","DOIUrl":"10.1016/j.jaacop.2024.10.003","url":null,"abstract":"","PeriodicalId":73525,"journal":{"name":"JAACAP open","volume":"2 4","pages":"Pages 326-328"},"PeriodicalIF":0.0,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11650675/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142856864","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Scope
JAACAP open Pub Date : 2024-12-01 DOI: 10.1016/S2949-7329(24)00080-2
{"title":"Scope","authors":"","doi":"10.1016/S2949-7329(24)00080-2","DOIUrl":"10.1016/S2949-7329(24)00080-2","url":null,"abstract":"","PeriodicalId":73525,"journal":{"name":"JAACAP open","volume":"2 4","pages":"Page A1"},"PeriodicalIF":0.0,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143164543","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Scope 范围
JAACAP open Pub Date : 2024-08-27 DOI: 10.1016/S2949-7329(24)00052-8
{"title":"Scope","authors":"","doi":"10.1016/S2949-7329(24)00052-8","DOIUrl":"10.1016/S2949-7329(24)00052-8","url":null,"abstract":"","PeriodicalId":73525,"journal":{"name":"JAACAP open","volume":"2 3","pages":"Page A1"},"PeriodicalIF":0.0,"publicationDate":"2024-08-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2949732924000528/pdfft?md5=50a5896191b6919883411fc7b940f3a6&pid=1-s2.0-S2949732924000528-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142083536","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Adolescent Sleep as a Transdiagnostic Factor: Associations Between Actigraphy-Derived Night-to-Night Sleep Metrics and Adolescent Psychopathology 作为跨诊断因素的青少年睡眠:动觉仪得出的夜间睡眠指标与青少年心理病理学之间的关系
JAACAP open Pub Date : 2024-07-01 DOI: 10.1016/j.jaacop.2024.06.001
Eric M Phillips, Emily L. Goldberg, R. L. Brock, Emily R. Hamburger, J. Nelson, W. A. Mason, K. Espy, Timothy D. Nelson
{"title":"Adolescent Sleep as a Transdiagnostic Factor: Associations Between Actigraphy-Derived Night-to-Night Sleep Metrics and Adolescent Psychopathology","authors":"Eric M Phillips, Emily L. Goldberg, R. L. Brock, Emily R. Hamburger, J. Nelson, W. A. Mason, K. Espy, Timothy D. Nelson","doi":"10.1016/j.jaacop.2024.06.001","DOIUrl":"https://doi.org/10.1016/j.jaacop.2024.06.001","url":null,"abstract":"","PeriodicalId":73525,"journal":{"name":"JAACAP open","volume":"33 2","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141702782","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The Course of Parental Psychological Distress in Childhood and Adolescent Depression 父母心理压力对儿童和青少年抑郁症的影响过程
JAACAP open Pub Date : 2024-07-01 DOI: 10.1016/j.jaacop.2024.05.003
Katia Mace, Maria Sifaki, Emily Midouhas, E. Flouri, E. Papachristou
{"title":"The Course of Parental Psychological Distress in Childhood and Adolescent Depression","authors":"Katia Mace, Maria Sifaki, Emily Midouhas, E. Flouri, E. Papachristou","doi":"10.1016/j.jaacop.2024.05.003","DOIUrl":"https://doi.org/10.1016/j.jaacop.2024.05.003","url":null,"abstract":"","PeriodicalId":73525,"journal":{"name":"JAACAP open","volume":"87 2","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141694231","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Family Factors Associated With Delinquency Outcomes in Court-Involved Youth in Mental Health Treatment 与接受心理健康治疗的法庭涉案青少年犯罪结果相关的家庭因素
JAACAP open Pub Date : 2024-07-01 DOI: 10.1016/j.jaacop.2024.05.004
Elizabeth M. Olsen, L. Whiteley, Marina Tolou-Shams, Christianne Esposito-Smythers, Larry K. Brown
{"title":"Family Factors Associated With Delinquency Outcomes in Court-Involved Youth in Mental Health Treatment","authors":"Elizabeth M. Olsen, L. Whiteley, Marina Tolou-Shams, Christianne Esposito-Smythers, Larry K. Brown","doi":"10.1016/j.jaacop.2024.05.004","DOIUrl":"https://doi.org/10.1016/j.jaacop.2024.05.004","url":null,"abstract":"","PeriodicalId":73525,"journal":{"name":"JAACAP open","volume":"9 5","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141702845","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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