Advances in integrative medicine最新文献

{"title":"From microbes to medals: Integrative gut microbiome interventions for athletic excellence","authors":"Emad M. Abdallah, Ahmed Emad Mohamed, Ozwan Moatasem Hassan, Sameh Yasser Amin, Waleed Hamid Aghbash","doi":"10.1016/j.aimed.2025.100582","DOIUrl":"10.1016/j.aimed.2025.100582","url":null,"abstract":"","PeriodicalId":7343,"journal":{"name":"Advances in integrative medicine","volume":"12 4","pages":"Article 100582"},"PeriodicalIF":1.7,"publicationDate":"2025-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145262308","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effect of an intervention grounded in the health action process approach on obesity surgery outcomes among bariatric surgery patients after one year: A randomized-controlled trial protocol","authors":"Elham Shakibazadeh,&nbsp;Maryam Maghsoodlo,&nbsp;Mehdi Yaseri,&nbsp;Zeinab Mokhtari,&nbsp;Maryam Barzin,&nbsp;Yahya Salimi","doi":"10.1016/j.aimed.2025.100565","DOIUrl":"10.1016/j.aimed.2025.100565","url":null,"abstract":"<div><h3>Background</h3><div>Numerous studies have demonstrated that a significant number of individuals experience weight regain following bariatric surgery. To sustain long-term weight loss outcomes, it is imperative to assist patients in adopting and maintaining healthy lifestyle changes. Implementing cognitive interventions aimed at enhancing self-management behaviors is crucial in supporting patients' efforts to sustain weight loss post-surgery.</div></div><div><h3>Materials and methods</h3><div>This paper outlines a protocol for a randomized controlled trial with two arms. The sample will consist of 100 patients who have undergone bariatric surgery and are part of the Tehran Obesity Treatment Study. The participants will be randomly assigned to either the intervention group or the control group. The intervention group will receive an educational intervention based on the health action process approach for a duration of eight weeks. The inclusion criteria for this study are patients who have undergone bariatric surgery at least one year prior to the study. All primary and secondary outcomes will be measured at two different time points: baseline and four months after the completion of the intervention, for each participant.</div></div><div><h3>Conclusion</h3><div>The results of this study offer valuable insights into the advantages of theory-based educational interventions in improving outcomes of bariatric surgery. These findings present an opportunity for health planners, practitioners, nurses specializing in bariatric surgery care, policy makers, and patients to utilize an effective intervention in the field.</div></div>","PeriodicalId":7343,"journal":{"name":"Advances in integrative medicine","volume":"12 4","pages":"Article 100565"},"PeriodicalIF":1.7,"publicationDate":"2025-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144903144","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Investigating the effects of applying low acoustic frequencies on the pain from venous and arterial blood sampling: A clinical trial study","authors":"Saeed Mohammadi ,&nbsp;Ebrahim Ezzati ,&nbsp;Rooghaye Mahooti ,&nbsp;Fatemeh Kavyannejad ,&nbsp;Mohammad Sadegh Paran ,&nbsp;Rasoul Kavyannejad","doi":"10.1016/j.aimed.2025.100480","DOIUrl":"10.1016/j.aimed.2025.100480","url":null,"abstract":"<div><h3>Background</h3><div>The pain of the blood sampling process is an unpleasant and common experience in the treatment process. Stimulation the thalamus structure and corticothalamic pathways with at specific frequencies could play a role in modulating pain perception. The aim of this study was to investigate the use low acoustic frequencies in reducing pain during arterial and venous blood sampling.</div></div><div><h3>Material and Methods</h3><div>In a triple-blinded clinical trial study, 300 patients in each process were randomly divided into control and intervention groups. Patients in the intervention groups received sound frequencies of 10–200 Hz with an intensity of 50 dB during the procedures. Pain intensity, heart rate changes, number of attempts for successful sampling, and time required for each procedure were measured. Data were analyzed using Prism 10 software.</div></div><div><h3>Results</h3><div>Pain levels were significantly lower in the intervention groups with increasing sound frequencies in both procedures (P &lt; 0.05). The duration of blood sampling procedures was significantly shorter with increasing sound frequency (P &lt; 0.05), but no difference was observed in the frequency of sampling attempts (P &gt; 0.05). By increasing the sound frequency, the intensity of tachycardia significantly decreased following the blood sampling process (P &lt; 0.05), especially at higher frequencies.</div></div><div><h3>Conclusion</h3><div>Applying low sound frequencies effectively could reduce acute pain and its consequences resulting from an invasive process. Sound frequencies appear to play a role in modulating pain pathways in the central nervous system.</div></div><div><h3>Implications for Clinical Practice</h3><div>The study findings suggest that sound frequency ranges as a non-pharmacological analgesia intervention can be used to reduce pain and discomfort following a variety of blood sampling procedures, which performed by nurses.</div></div>","PeriodicalId":7343,"journal":{"name":"Advances in integrative medicine","volume":"12 4","pages":"Article 100480"},"PeriodicalIF":1.7,"publicationDate":"2025-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144518768","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effect of geriatric massage in elderly patients with type 2 diabetes: A randomized controlled trial","authors":"Emine Apaydın ,&nbsp;Sevilay Hintistan","doi":"10.1016/j.aimed.2025.100581","DOIUrl":"10.1016/j.aimed.2025.100581","url":null,"abstract":"<div><h3>Objective</h3><div>This randomized controlled trial examined the effects of geriatric massage on diabetes-related symptoms and blood parameters in older adults with type 2 diabetes. The study included 59 participants (29 in the geriatric massage group and 30 in the control group).</div></div><div><h3>Methods</h3><div>Data were collected using the Older Adults Information Form, the Diabetes Symptoms Checklist, and the Blood Parameters Monitoring Form. Participants in the intervention group received 30-minute geriatric massage sessions twice weekly for 12 weeks. Statistical analyses included the Shapiro–Wilk test, Mann–Whitney U test, ANOVA, Friedman test, Wilcoxon test, Chi-square test, Fisher–Freeman–Halton test, Greenhouse–Geisser correction, Bonferroni adjustment, and paired and independent t-tests.</div></div><div><h3>Results</h3><div>Compared with the control group, participants receiving geriatric massage showed a significant reduction in diabetes symptoms (p &lt; 0.001), an increase in HDL cholesterol levels, and decreases in other blood parameters (p &lt; 0.05).</div></div><div><h3>Discussion</h3><div>Geriatric massage may help reduce diabetes symptoms and improve selected blood parameters in older adults with type 2 diabetes.</div></div>","PeriodicalId":7343,"journal":{"name":"Advances in integrative medicine","volume":"12 4","pages":"Article 100581"},"PeriodicalIF":1.7,"publicationDate":"2025-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145358028","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Bibliotherapy for adverse childhood experience: A systematic review","authors":"Luana Lenzi ,&nbsp;Jack Adlard ,&nbsp;Grace Rosina Pangrazi ,&nbsp;Saima Bashir ,&nbsp;Elaine Bousfield ,&nbsp;Alexander Thompson","doi":"10.1016/j.aimed.2025.100492","DOIUrl":"10.1016/j.aimed.2025.100492","url":null,"abstract":"<div><h3>Objective</h3><div>This systematic review aims to identify, describe, and evaluate the available evidence regarding the effectiveness of bibliotherapy in supporting individuals to overcome adverse childhood experiences (ACE).</div></div><div><h3>Methods</h3><div>A systematic search was performed using Medline, Embase, APA PsycInfo and PubMed. Studies were included if they involved participants of any age who had experienced any form of ACE during childhood and had received bibliotherapy as a form of treatment or support. Risk of bias was assesses using RoB 2 and ROBINS-I as appropriate and results were narratively synthesised (PROSPERO CRD42023404418).</div></div><div><h3>Results</h3><div>Out of the 606 studies identified, only five met the inclusion criteria, comprising four RCTs and one non-RCT. The interventions included superhero and affective bibliotherapy, a community-based initiative designed to foster a love for reading among children while creating a safe and engaging environment, explicit bibliotherapy, a support group integrating indigenous stories with cognitive behavioural therapy components, and poetry therapy. These interventions were compared against alternative interventions or waitlist controls. Although the evidence was limited and of moderate to low quality, the findings suggest that bibliotherapy may help reduce ACE-related outcomes such as anxiety, grief, and PTSD, enhances emotional competence, provides a higher sense of support compared to waitlist. The included studies were not directly comparable due to high heterogeneity in study design, intervention methods ad outcomes assessment.</div></div><div><h3>Conclusions</h3><div>This systematic review highlights the need for further research into the use of bibliotherapy for managing ACE. Cautious implementation of bibliotherapy as an adjunct treatment to complement traditional therapy may enhance and prolong positive outcomes.</div></div>","PeriodicalId":7343,"journal":{"name":"Advances in integrative medicine","volume":"12 4","pages":"Article 100492"},"PeriodicalIF":1.7,"publicationDate":"2025-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144516991","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Ethnopharmacology of Calotropis procera: Traditional knowledge and scientific insights from Dodoma Region, Tanzania","authors":"Hamisi Yunus Nchimbi","doi":"10.1016/j.aimed.2025.100535","DOIUrl":"10.1016/j.aimed.2025.100535","url":null,"abstract":"<div><h3>Introduction</h3><div>This study explored the integration of traditional knowledge and contemporary science in the ethnopharmacology of <em>Calotropis procera</em> in the Kongwa District, Dodoma region in Tanzania.</div></div><div><h3>Method</h3><div>A cross-sectional design combining qualitative interviews with 110 respondents from Lenjulu and Majawanga villages, alongside laboratory analyses, was employed. These included preliminary phytochemical screening, GC–MS complemented by LC-MS, and in vitro antimicrobial assays using the microdilution method in 96-well microtiter plates.</div></div><div><h3>Results</h3><div>Ethnobotanical data revealed that traditional knowledge of <em>C. procera</em> is predominantly held by older community members, with 41.8 % of respondents above 55 years, and is transmitted mainly through intergenerational transfer, apprenticeships, and gender-specific roles. Phytochemical screening confirmed the presence of key bioactive compounds such as phenols, flavonoids, alkaloids, tannins, saponins, terpenoids, and steroids, validating its traditional use in treating ailments. The chemical profiling of <em>C. procera</em> using LC-MS and GC-MS revealed several dominant bioactive compounds across multiple pharmacological classes. For example, LC-MS analysis identified amino acids L-Tyrosine (12.73 %) and L-Isoleucine (8.92 %) and a flavonoid Quercetin (9.65 %), indicating their abundance and potential biological significance. GC-MS results highlighted a sesquiterpene Caryophyllene (8.12 %)<strong>,</strong> a diterpene Neophytadiene (4.92 %) and a triterpenoid Squalene (3.56 %), all are known for anti-inflammatory and antimicrobial activities. These findings underscore the phytochemical richness and therapeutic potential of <em>C. procera</em>. In vitro antimicrobial assays revealed pronounced antibacterial efficacy of the <em>C. procera</em>, with B.subtilis exhibiting the highest susceptibility (MIC: 7.03 mg/L), followed by S.typhi (MIC: 14.06 mg/L), E.coli (MIC: 28.13 mg/L), and S.aureus (MIC: 56.25 mg/L). The observed activity is attributed to the presence of bioactive phytochemical constituents, underscoring the plant’s ethnopharmacological relevance as a promising source of natural antibacterial compounds.</div></div><div><h3>Conclusion</h3><div>These findings support the therapeutic potential of <em>C. procera and underscore the critical need to preserve traditional medical knowledge for future healthcare applications.</em></div></div><div><h3>Take-home message</h3><div>Preserving the traditional knowledge of <em>C. procera</em> in Kongwa District is essential for future pharmaceutical and medical breakthroughs, as scientific validation has confirmed its strong antibacterial properties.</div></div>","PeriodicalId":7343,"journal":{"name":"Advances in integrative medicine","volume":"12 4","pages":"Article 100535"},"PeriodicalIF":1.7,"publicationDate":"2025-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144516992","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effects of art therapy interventions on satisfaction with life: A systematic review and meta-analysis","authors":"Javier Fernández-Sánchez ,&nbsp;Daniel Trujillo-Colmena ,&nbsp;Daniel Collado-Mateo ,&nbsp;Juan Luis Leon-Llamas ,&nbsp;Ana Myriam Lavín-Pérez ,&nbsp;Miriam Lorenzo-González","doi":"10.1016/j.aimed.2025.100532","DOIUrl":"10.1016/j.aimed.2025.100532","url":null,"abstract":"<div><div>Art therapies have emerged as a cost-effective global resource for promoting wellbeing, and quality of life and for reducing mental health problems through mind-body connection and creative expression. The aim was to systematically review the current evidence about the benefits of dance and theater-based interventions on the life satisfaction of participants. Furthermore, this study is aimed to synthesize and meta-analyze the results of the previously published randomized controlled trials. Thus, to identify the articles, a systematic search was conducted in PubMed (Medline) and Web of Science. The inclusion criteria included: being a randomized controlled trial, evaluating the effects of dance or drama interventions and providing pre-post data showing the effects on life satisfaction. A total of 12 articles were included in the Systematic Review, with 8 of them being included in the meta-analysis. Meta-analysis results showed that dance and drama interventions are effective (p = 0.01) in increasing the satisfaction with life of participants with different ages and conditions. In conclusion, dance and theater-based interventions are two forms of art therapies that may be useful to enhance the life satisfaction of people. Furthermore, further studies are needed to make stronger evidence-based recommendations or comparisons to other types of physical activity.</div></div>","PeriodicalId":7343,"journal":{"name":"Advances in integrative medicine","volume":"12 4","pages":"Article 100532"},"PeriodicalIF":1.7,"publicationDate":"2025-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144516980","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Complementary and alternative medicine use among pediatric cancer patients: A cross-sectional study from a large healthcare system in Saudi Arabia","authors":"Mohammad Alkaiyat ,&nbsp;Reem Al Sudairy ,&nbsp;Reem Abdel Lateef ,&nbsp;Abdul Rahman Jazieh","doi":"10.1016/j.aimed.2025.100575","DOIUrl":"10.1016/j.aimed.2025.100575","url":null,"abstract":"<div><div>Complementary and alternative medicine (CAM) is commonly used among patients with cancer, with most studies focusing on its use in adults. However, only a few studies have specifically focused on pediatric patients with cancer, with no studies reported in the Gulf area. This study investigated the prevalence and pattern of CAM use among pediatric patients with cancer in Saudi Arabia. In this descriptive cross-sectional study, a validated questionnaire was used to collect data from 211 caregivers of pediatric patients with cancer who received care at the pediatric oncology department at King Abdulaziz Medical City. The prevalence of CAM use was 90 % (95 % CI = 85 %–93 %). The most prominent category of CAM used was alternative (nondietary) treatment (184; 87.2 %), which included reading the Quran (165; 86.8 %) and use of olive oil as a lotion (91; 47.6 %). In contrast, complementary (dietary) treatment was less prevalent (60; 28.4 %). The most common complementary treatments were drinking Zamzam water (59; 31.1 %) and consuming honey (37; 19.5 %). Among the caregivers who used CAM for their children and reported improvements, most of them (49; 81 %) attributed this improvement to CAM and standard medical treatment, whereas only six (5.2 %) attributed it to CAM alone. A few number of children received risky CAM products (camel urine with milk, traditional cautery). Most caregivers did not discuss the use of CAM with their children’s oncologists. CAM use was prevalent among pediatric patients with cancer, with no significant associations with demographic or disease characteristics.</div></div>","PeriodicalId":7343,"journal":{"name":"Advances in integrative medicine","volume":"12 4","pages":"Article 100575"},"PeriodicalIF":1.7,"publicationDate":"2025-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145044705","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Sedentary lifestyle and occupational stress: Rethinking employee wellness through culturally attuned yoga","authors":"Erma Pratiwi Nufi","doi":"10.1016/j.aimed.2025.100568","DOIUrl":"10.1016/j.aimed.2025.100568","url":null,"abstract":"","PeriodicalId":7343,"journal":{"name":"Advances in integrative medicine","volume":"12 4","pages":"Article 100568"},"PeriodicalIF":1.7,"publicationDate":"2025-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144917053","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Promoting emotional resilience through laughter yoga in health professions education","authors":"Manuel Millán-Hernández ,&nbsp;Daniela F. Albarrán-Pérez","doi":"10.1016/j.aimed.2025.100527","DOIUrl":"10.1016/j.aimed.2025.100527","url":null,"abstract":"","PeriodicalId":7343,"journal":{"name":"Advances in integrative medicine","volume":"12 4","pages":"Article 100527"},"PeriodicalIF":1.7,"publicationDate":"2025-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144501066","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}