Phytochemistry Reviews最新文献_第3页

Polyphenols and terpenoids derived from Ocimum species as prospective hepatoprotective drug leads: a comprehensive mechanistic review 从欧芹中提取的多酚类和萜类化合物作为未来的保肝药物线索：全面的机理综述

IF 7.7 2区生物学

Phytochemistry Reviews Pub Date : 2024-07-12 DOI: 10.1007/s11101-024-09992-2

Amrita Chatterjee, Biswatrish Sarkar

{"title":"Polyphenols and terpenoids derived from Ocimum species as prospective hepatoprotective drug leads: a comprehensive mechanistic review","authors":"Amrita Chatterjee, Biswatrish Sarkar","doi":"10.1007/s11101-024-09992-2","DOIUrl":"https://doi.org/10.1007/s11101-024-09992-2","url":null,"abstract":"The hepatic regulatory role in metabolism involves exposure to a diverse array of xenobiotic compounds leading to the potential accumulation of harmful toxins and subsequent manifestation of hepatic conditions such as steatosis, fibrosis, and cirrhosis. Herbs as part of culinary and traditional uses have demonstrated therapeutic effects against such conditions. Predominant among the dietary constituents are polyphenols and terpenoids, which are known for their liver-protective efficacies. Evident from their antioxidant and anti-inflammatory properties and modulation of antioxidant enzymes this class of phytochemicals regulates pivotal liver biomarkers. Ocimum species, notably Tulsi, are recognized for their abundant repertoire of terpenoids and polyphenols. From time immemorial, owing to its diverse biological properties, the Ocimum species has made its way into our culinary habits and traditions. Clinical findings have indicated the beneficial effects of Ocimum sanctum on the biochemical parameters of the liver in young overweight/obese subjects. However, despite several pre-clinical, and clinical studies elucidating the hepatoprotective potential of Ocimum species, a comprehensive understanding of the molecular mechanism underlying the actions of phenolic and terpenoid phytoconstituents is lacking till date. Consequently, targeted molecular therapies involving Ocimum species are yet to be developed. Thus, this mechanistic review was aimed at elucidating the intricate molecular pathways through which polyphenols and terpenoids derived from Ocimum species exert their hepatoprotective effects. By correlating these molecular mechanisms, insights into the hepatoprotective abilities of polyphenols and terpenoids found in Ocimum species were provided, which may pave the way for potential targeted therapeutic interventions.<h3 data-test=\"abstract-sub-heading\">Graphical abstract</h3>\u0000","PeriodicalId":733,"journal":{"name":"Phytochemistry Reviews","volume":null,"pages":null},"PeriodicalIF":7.7,"publicationDate":"2024-07-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141611980","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Sticky business: the intricacies of acylsugar biosynthesis in the Solanaceae 粘性业务：茄科植物酰基糖生物合成的复杂性

IF 7.7 2区生物学

Phytochemistry Reviews Pub Date : 2024-07-12 DOI: 10.1007/s11101-024-09996-y

Eloisa Vendemiatti, Lillian Nowack, Lazaro Eustáquio Pereira Peres, Vagner A. Benedito, Craig A. Schenck

{"title":"Sticky business: the intricacies of acylsugar biosynthesis in the Solanaceae","authors":"Eloisa Vendemiatti, Lillian Nowack, Lazaro Eustáquio Pereira Peres, Vagner A. Benedito, Craig A. Schenck","doi":"10.1007/s11101-024-09996-y","DOIUrl":"https://doi.org/10.1007/s11101-024-09996-y","url":null,"abstract":"Plants display tremendous chemical diversity. Like all organisms, they possess a core set of metabolites for growth and development. However, plants are notorious for their specialized chemical repertoire. Biologically active specialized metabolites enable plants to interact with their environment and provide humans with diverse medicines. Specialized metabolites are derived from core metabolites, often using enzymes that evolved from core pathways in a lineage-specific manner. Biochemical understanding of plant specialized metabolic pathways provides insight into the evolutionary origins of chemical diversity and tools for engineering the production of biologically active metabolites. Acylsugars are a class of specialized metabolites occurring widely in the Solanaceae and other plant families where they contribute to fitness. Although assembled from simple core metabolic precursors, sugars and acyl chains, tremendous acylsugar structural diversity is observed across the Solanaceae family. Enzymes that catalyze the esterification of acyl chains to sugar cores have been well characterized from phylogenetically diverse species, and their biochemical diversity contributes to acylsugar structural variation. The upstream metabolic pathways that provide the acyl chain precursors also contribute to acylsugar structural variation. Yet, biochemical and genetic understanding of these upstream biosynthetic pathways is less well known. Here, we focus on recent advances in acyl chain biosynthesis and elongation pathways, the subcellular distribution of acylsugar biosynthesis, and how biochemical innovations in acylsugar biosynthesis contribute to structural diversity specifically focusing on Solanaceae-type acylsugars.","PeriodicalId":733,"journal":{"name":"Phytochemistry Reviews","volume":null,"pages":null},"PeriodicalIF":7.7,"publicationDate":"2024-07-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141611957","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Giant milkweed: a comprehensive review of chemical constituents and their insecticidal properties 巨型乳草：化学成分及其杀虫特性的全面回顾

IF 7.7 2区生物学

Phytochemistry Reviews Pub Date : 2024-07-12 DOI: 10.1007/s11101-024-09986-0

K. Mounisha, Y. S. Johnson Thangaraj Edward, M. Kannan, S. Vellaikumar, D. Uma, P. Indiragandhi

{"title":"Giant milkweed: a comprehensive review of chemical constituents and their insecticidal properties","authors":"K. Mounisha, Y. S. Johnson Thangaraj Edward, M. Kannan, S. Vellaikumar, D. Uma, P. Indiragandhi","doi":"10.1007/s11101-024-09986-0","DOIUrl":"https://doi.org/10.1007/s11101-024-09986-0","url":null,"abstract":"Calotropis gigantea (L.) W.T. Aiton, a common barren land weed, referred to as Giant Milkweed, has attracted considerable attention due to its rich abundance of phytochemicals possessing potent insecticidal properties. The review extensively explores the varied spectrum of chemical compounds present in C. gigantea, ranging from giganticine and ethion to stigmastan-6,22-dien,3,5-dedihydro-, β-amyrin, and others, offering detailed explanation about their structural diversity and potential applications. The primary focus is on a detailed evaluation of the insecticidal properties shown by these compounds against a wide range of insects, which collectively reinforce the natural insecticidal effectiveness of C. gigantea. This diligent study provides a thorough understanding on the individual effects of the compounds against insects, revealing their vital role in the development of innovative pest management strategies. This review aims to seek a comprehensive overview of the chemical constituents within this botanical resource that give a deep knowledge on their insecticidal characteristics. The ultimate aim is to pave the way for future research and practical applications in integrated pest management practices, contributing to the sustainable agriculture.","PeriodicalId":733,"journal":{"name":"Phytochemistry Reviews","volume":null,"pages":null},"PeriodicalIF":7.7,"publicationDate":"2024-07-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141611978","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

An updated and comprehensive review of traditional uses, phytochemistry, and pharmacological progress on the Hypecoum genus 对 Hypecoum 属植物的传统用途、植物化学和药理研究进展的最新全面综述

IF 7.7 2区生物学

Phytochemistry Reviews Pub Date : 2024-07-09 DOI: 10.1007/s11101-024-09985-1

Hai-Lian Yuan, Li Zhang, Wen-Hao Huang, Chang-Gang Sun, Xiao-Dong Luo

{"title":"An updated and comprehensive review of traditional uses, phytochemistry, and pharmacological progress on the Hypecoum genus","authors":"Hai-Lian Yuan, Li Zhang, Wen-Hao Huang, Chang-Gang Sun, Xiao-Dong Luo","doi":"10.1007/s11101-024-09985-1","DOIUrl":"https://doi.org/10.1007/s11101-024-09985-1","url":null,"abstract":"The Hypecoum genus belongs to the family Papaveraceae, consists of roughly 16 accepted species, and is extensively distributed from the Mediterranean to Central Asia and Northern China. It was used widely for the treatment of sore throat, tracheitis, cough, hepatitis, bronchitis, bacterial dysentery, and conjunctive congestion with swelling and pain disease in traditional Chinese and other countries’ medicine, especially in Tibetan or Mongolian medicine. Based on “Hypecoum”, a total of 163 relevant papers published since 1924 were meticulously selected through comprehensive searches of the American Chemical Society (ACS), PubMed, Web of Science, and Science Direct databases. Modern pharmacological researches have evaluated its various biological activities, such as analgesic, anti-inflammatory, antibacterial, hepatoprotective, and antiproliferative activities, even the assessment of its potential for mitigating the impact of corona virus disease 2019 (COVID-19). Approximately 100 alkaloids have been obtained and identified from the Hypecoum species, as well as flavonoid, volatile oil, phenolic, and aromatic compounds. Additionally, the Hypecoum species is widely used in traditional Chinese medicine (TCM) formulae, partial efficacies of which have been verified via numerous pharmacological and clinical investigations, particularly in the treatment of inflammatory and pain diseases. This reviews performed an exhaustive literature review to bridge the knowledge gap that there has yet to be a comprehensive and systematic review addressing the botany, traditional uses, phytochemicals, pharmacological effects, and underlying mechanisms associated with Hypecoum genus. The ultimate aim is to facilitate a solid foundation for the modern research and development of Hypecoum spp., thereby contributing to scientific advancement and enhancing the existing literature in this field.<h3 data-test=\"abstract-sub-heading\">Graphical abstract</h3>","PeriodicalId":733,"journal":{"name":"Phytochemistry Reviews","volume":null,"pages":null},"PeriodicalIF":7.7,"publicationDate":"2024-07-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141570582","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Sustainable extraction methods for the recovery of polyphenolic compounds from grape pomace and its biological properties: a comprehensive review 从葡萄渣及其生物特性中回收多酚化合物的可持续萃取方法：综述

IF 7.7 2区生物学

Phytochemistry Reviews Pub Date : 2024-07-05 DOI: 10.1007/s11101-024-09991-3

Luiz Eduardo Nochi Castro, William Gustavo Sganzerla, Aline Priscilla Gomes Silva, Oliver Dean John, Tiago Linhares Cruz Tabosa Barroso, Mauricio A. Rostagno, Tânia Forster-Carneiro

{"title":"Sustainable extraction methods for the recovery of polyphenolic compounds from grape pomace and its biological properties: a comprehensive review","authors":"Luiz Eduardo Nochi Castro, William Gustavo Sganzerla, Aline Priscilla Gomes Silva, Oliver Dean John, Tiago Linhares Cruz Tabosa Barroso, Mauricio A. Rostagno, Tânia Forster-Carneiro","doi":"10.1007/s11101-024-09991-3","DOIUrl":"https://doi.org/10.1007/s11101-024-09991-3","url":null,"abstract":"Grape pomace (seeds, skin, and stalks) holds promise as a feedstock for various industrial applications. This comprehensive review describes advancements in sustainable and novel extraction processes for recovering polyphenolic compounds and their biological properties. In contrast to traditional methods, sustainable extraction techniques such as microwave-assisted, ultrasound-assisted, pressurized liquid, enzyme-assisted, and hydrothermal processes have been applied to produce high-quality and safe extracts. These methods utilize non-toxic solvents, maintain moderate temperatures, achieve fast extraction times, and require low energy input. The polyphenolic compounds, particularly flavan-3-ols, anthocyanins, and proanthocyanidins extracted from grape pomace, exhibit a wide range of biological properties, including anti-inflammatory, anti-obesity, antioxidant, antidiabetic, hepatoprotective, anticancer, antimicrobial, and heart health-promoting effects. They also contribute to enhancing the gut microbiota population, promoting health. In conclusion, emerging extraction methods offer a sustainable approach to producing bioactive compounds from grape pomace for use in the cosmetic, pharmaceutical, and food industries.\u0000","PeriodicalId":733,"journal":{"name":"Phytochemistry Reviews","volume":null,"pages":null},"PeriodicalIF":7.7,"publicationDate":"2024-07-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141547127","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Symphytum genus—from traditional medicine to modern uses: an update on phytochemistry, pharmacological activity, and safety Symphytum 属--从传统医药到现代用途：植物化学、药理活性和安全性方面的最新进展

IF 7.7 2区生物学

Phytochemistry Reviews Pub Date : 2024-07-03 DOI: 10.1007/s11101-024-09977-1

Adriana Trifan, Evelyn Wolfram, Krystyna Skalicka-Woźniak, Simon Vlad Luca

{"title":"Symphytum genus—from traditional medicine to modern uses: an update on phytochemistry, pharmacological activity, and safety","authors":"Adriana Trifan, Evelyn Wolfram, Krystyna Skalicka-Woźniak, Simon Vlad Luca","doi":"10.1007/s11101-024-09977-1","DOIUrl":"https://doi.org/10.1007/s11101-024-09977-1","url":null,"abstract":"With around 34 recognized species, Symphytum genus (comfrey) has a noteworthy position within the Boraginaceae family. Comfrey species have been empirically used since ancient times as wound-healing and skin-regenerating agents in ulcers, wounds, bone fractures, and rheumatic complaints. This review aims to provide a thorough examination of recent scientific advances and challenges within the Symphytum genus, covering data published between 2013 and 2023. It delivers an updated overview of the taxonomy, ethnopharmacological uses, chemical composition, and pharmacological activities of the genus. Special emphasis is put on molecular identification methods for species taxonomy, emerging extraction technologies for comfrey phytochemicals, metabolomics techniques for mapping chemical complexity, modern bioassay platforms revealing its poly-pharmacology, formulation strategies, and remediation approaches for removal of toxic pyrrolizidine alkaloids (PAs). For instance, recent metabolomic studies employing advanced spectro-chromatographic techniques have revealed a diverse chemical composition of comfrey plants, including polysaccharides, allantoin, benzoic and cinnamic acid derivatives, flavonoids, fatty acids, and unsaturated necine-structure-based PAs. The mechanisms underlying their anti-inflammatory, analgesic, wound-healing, anti-irritant, and osteo-regenerative properties were targeted in modern pharmacological setups. Thus, key compounds like allantoin, rosmarinic acid, globoidnans A and B, rabdosiin, and comfreyn A, have been identified as significant contributors to the anti-inflammatory and wound-healing effects of Symphytum-derived preparations. Despite their well-established clinical use, concerns about PAs-induced toxicity have prompted the development of novel PA remediation strategies, enabling the production of comfrey extracts with enhanced safety profiles that can meet the regulatory standards imposed by authorities.","PeriodicalId":733,"journal":{"name":"Phytochemistry Reviews","volume":null,"pages":null},"PeriodicalIF":7.7,"publicationDate":"2024-07-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141547128","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

A comprehensive review on essential oils and extracts from Iris rhizomes 鸢尾根茎中的精油和提取物综述

IF 7.7 2区生物学

Phytochemistry Reviews Pub Date : 2024-07-03 DOI: 10.1007/s11101-024-09981-5

Carlo Bicchi, Daniel Joulain

引用次数: 0

Antiviral potential of essential oils and their plant sources, delivery methods, and drug development strategies with special focus on their mechanisms: a comprehensive review 精油的抗病毒潜力及其植物来源、给药方法和药物开发战略，特别关注其机制：综合综述

IF 7.7 2区生物学

Phytochemistry Reviews Pub Date : 2024-06-28 DOI: 10.1007/s11101-024-09983-3

Anjie Feng, Tiantian Si, Baoxiang Du, Qihui Sun, Yong Yang, Rong Rong

{"title":"Antiviral potential of essential oils and their plant sources, delivery methods, and drug development strategies with special focus on their mechanisms: a comprehensive review","authors":"Anjie Feng, Tiantian Si, Baoxiang Du, Qihui Sun, Yong Yang, Rong Rong","doi":"10.1007/s11101-024-09983-3","DOIUrl":"https://doi.org/10.1007/s11101-024-09983-3","url":null,"abstract":"The rise in viral infections has presented a multitude of public health concerns on a global scale, including the emergence of influenza and SARS-CoV-2. The emergence of drug-resistant virus strains has underscored the paramount importance of expedited research in the development of novel antiviral therapeutics. It has led to a surge in interest in the potential application of essential oils (EOs) as antiviral agents, owing to their noteworthy antiviral efficacy. A considerable number of EOs and their components have demonstrated promising antiviral activities in vitro and in vivo research. This review provided an overview of the various aspects of EOs inhibiting viruses, including plant sources, the different delivery methods, current challenges and strategies for developing drugs, and in-depth discussions on the relevant mechanisms. It concisely explores the antiviral mechanisms of EOs, ranging from molecular docking simulations to in-depth cellular, animal, and human studies. EOs demonstrate antiviral potential by inhibiting viral proteins, disrupting replication, and modulating host cellular functions, immune responses, and nervous system interactions. This review serves as a valuable resource for researchers and pharmaceutical entities, offering insights and references that advance the antiviral research and innovative drug development utilizing plant-derived essential oils.<h3 data-test=\"abstract-sub-heading\">Graphical abstract</h3>","PeriodicalId":733,"journal":{"name":"Phytochemistry Reviews","volume":null,"pages":null},"PeriodicalIF":7.7,"publicationDate":"2024-06-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141507256","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The genus Pittosporum: current knowledge on traditional use, phytochemistry, and pharmacological activity 海桐属：关于传统用途、植物化学和药理活性的现有知识

IF 7.7 2区生物学

Phytochemistry Reviews Pub Date : 2024-06-27 DOI: 10.1007/s11101-024-09990-4

Nguyen Thi Thuy Linh, Nguyen Van Tuyen, Ty Viet Pham, Suresh Awale, Ninh The Son

{"title":"The genus Pittosporum: current knowledge on traditional use, phytochemistry, and pharmacological activity","authors":"Nguyen Thi Thuy Linh, Nguyen Van Tuyen, Ty Viet Pham, Suresh Awale, Ninh The Son","doi":"10.1007/s11101-024-09990-4","DOIUrl":"https://doi.org/10.1007/s11101-024-09990-4","url":null,"abstract":"Background: Pittosporum (the family Pittosporaceae) contains flowering plants, which was used as folk medicines in some countries of Asia, Europe, and Africa. Traditional use and pharmacological values of plants in this genus were deduced from a great role of their secondary metabolites. Objective: The ultimate goal of the review fully provides significant information on traditional use, phytochemistry, and pharmacology of Pittosporum plants. Methods: The search for reference data is mostly based on electronic resources, such as Google Scholar, Sci-Finder, and Web of Science. “Pittosporum” is the most important keyword, in which it was used alone or combined with other words to seek literature documents. Results: Traditionally, Pittosporum species are on the recommended list for medicinal purposes and fragrance preparation. From the 1960s to the present, more than 270 metabolites have been isolated with the derivatives type terpenoids, saponins, and lignans being the main phytochemical classes. Essential oils derived from Pittosporum species were dominated by terpenoids and fatty acids. Accumulating evidence has firmly revealed that Pittosporum constituents generated a wide variety of pharmacological activities, including cytotoxic, anti-inflammatory, antioxidative, antimicrobial, antiparasitic, antiarrhythmic, antinociceptive, antimalarial, enzyme inhibitory, and hepatoprotective activities. Conclusion: Technological advances in the chromatographic isolation of huge amounts are desirable. Toxicological assessments are needed. In vivo pharmacological experiments, molecular mechanisms of action, and clinical evaluations are warranted.","PeriodicalId":733,"journal":{"name":"Phytochemistry Reviews","volume":null,"pages":null},"PeriodicalIF":7.7,"publicationDate":"2024-06-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141507257","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Specialized metabolites of the genus Zephyranthes Herb.: a critical review on taxonomy and phytochemistry Zephyranthes Herb.属的特殊代谢物：分类学和植物化学评论

IF 7.7 2区生物学

Phytochemistry Reviews Pub Date : 2024-06-26 DOI: 10.1007/s11101-024-09931-1

Marcela Šafratová, Rudolf Vrabec, Gerald Blunden, Lucie Cahlíková, Jana Křoustková

{"title":"Specialized metabolites of the genus Zephyranthes Herb.: a critical review on taxonomy and phytochemistry","authors":"Marcela Šafratová, Rudolf Vrabec, Gerald Blunden, Lucie Cahlíková, Jana Křoustková","doi":"10.1007/s11101-024-09931-1","DOIUrl":"https://doi.org/10.1007/s11101-024-09931-1","url":null,"abstract":"This article is a critical review of the taxonomy and phytochemistry of the genus Zephyranthes Herb., a group of plants known for their beautiful flowers and traditional medicinal uses. The present review summarizes the occurrence, isolation, and identification of specialized metabolites, which have recently been frequently studied because of their important biological activities. Among the accepted 203 species, only 27 have been phytochemically investigated. This paper provides an overview of the different types of specialized metabolites identified in these plants and considers problematic taxonomic evolution within this species. The differences between two internationally recognized databases, which classify only 41% of the species in the same way, are briefly summarized. In addition, there are many reports on their metabolites, especially alkaloids, but some of the data in the literature are occasionally inaccurate and sometimes even erroneous. This critical review aims to discuss, summarize, and evaluate up-to-date (up to July of 2023) information about metabolites of the genus Zephyranthes, focusing on phytochemistry and taxonomy.<h3 data-test=\"abstract-sub-heading\">Graphical abstract</h3>","PeriodicalId":733,"journal":{"name":"Phytochemistry Reviews","volume":null,"pages":null},"PeriodicalIF":7.7,"publicationDate":"2024-06-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141500583","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0