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[An abscess gone astray].
Innere Medizin (Heidelberg, Germany) Pub Date : 2025-02-19 DOI: 10.1007/s00108-025-01863-y
Hatti Seidl, Lena Thormählen, Marie Pollak, Thula Walter-Rittel, Robert Hättasch, Gerhard Hindricks
{"title":"[An abscess gone astray].","authors":"Hatti Seidl, Lena Thormählen, Marie Pollak, Thula Walter-Rittel, Robert Hättasch, Gerhard Hindricks","doi":"10.1007/s00108-025-01863-y","DOIUrl":"https://doi.org/10.1007/s00108-025-01863-y","url":null,"abstract":"<p><p>A 69-year-old female patient with known recurrence of esophageal cancer presented with fever and elevated inflammatory markers. In the recent past, a suspicious mediastinal lymph node had been biopsied via bronchoscopy. Consequently, a lymph node abscess developed, leading to blood stream infection (pathogen: Streptococcus anginosus) via a fistula into the superior vena cava. Through a preexisting atrial septal defect, the infection also spread to the brain, causing multiple brain abscesses.</p>","PeriodicalId":73385,"journal":{"name":"Innere Medizin (Heidelberg, Germany)","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-02-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143451164","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Real world data show effectiveness of new respiratory syncytial virus (RSV) vaccines].
Innere Medizin (Heidelberg, Germany) Pub Date : 2025-02-13 DOI: 10.1007/s00108-025-01852-1
Ulrich Matt, Sirka Nitschmann, Susanne Herold
{"title":"[Real world data show effectiveness of new respiratory syncytial virus (RSV) vaccines].","authors":"Ulrich Matt, Sirka Nitschmann, Susanne Herold","doi":"10.1007/s00108-025-01852-1","DOIUrl":"https://doi.org/10.1007/s00108-025-01852-1","url":null,"abstract":"","PeriodicalId":73385,"journal":{"name":"Innere Medizin (Heidelberg, Germany)","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-02-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143412000","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Liver transplantation in patients with unresectable colorectal liver metastases]. [无法切除的结直肠肝转移患者的肝移植]。
Innere Medizin (Heidelberg, Germany) Pub Date : 2025-02-12 DOI: 10.1007/s00108-024-01837-6
Markus Quante, Anna Saborowski, Sirka Nitschmann
{"title":"[Liver transplantation in patients with unresectable colorectal liver metastases].","authors":"Markus Quante, Anna Saborowski, Sirka Nitschmann","doi":"10.1007/s00108-024-01837-6","DOIUrl":"https://doi.org/10.1007/s00108-024-01837-6","url":null,"abstract":"","PeriodicalId":73385,"journal":{"name":"Innere Medizin (Heidelberg, Germany)","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-02-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143400881","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Resilience in the face of disaster: A prerequisite or a skill to be acquired? : A consideration of this question using Doctors Without Borders as an example].
Innere Medizin (Heidelberg, Germany) Pub Date : 2025-02-07 DOI: 10.1007/s00108-025-01855-y
Tankred Stöbe
{"title":"[Resilience in the face of disaster: A prerequisite or a skill to be acquired? : A consideration of this question using Doctors Without Borders as an example].","authors":"Tankred Stöbe","doi":"10.1007/s00108-025-01855-y","DOIUrl":"https://doi.org/10.1007/s00108-025-01855-y","url":null,"abstract":"<p><p>Little is known about the resilience of the most vulnerable people on this planet in disaster and war zones. However, addressing this topic can be of crucial importance for future adaptation strategies and individual preparation for difficult life circumstances. For Médecins Sans Frontières (MSF), resilience is becoming increasingly important in all areas of activity: in supporting refugees and internally displaced persons, in responding to the effects of global warming, following natural disasters, in wars, and in providing psychological support to aid workers as well as those that need help. This article discusses the definition of resilience, the interpretation of which is dynamic and multifaceted. Individual resilience can be gauged and reflected upon through self-interrogation. This article then deals with the safety of and risk faced by international and local aid workers in crisis areas as well as with the question of whether Doctors Without Borders can be considered a resilient organization. Finally, the article looks at how each individual aid worker can strengthen their personal resilience. Indeed, resilience can be trained, and we would do well to start straight away.</p>","PeriodicalId":73385,"journal":{"name":"Innere Medizin (Heidelberg, Germany)","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-02-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143366883","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Update on the pathophysiology, prediction and prevention of inflammatory bowel diseases]. [炎症性肠病的病理生理学、预测和预防进展]。
Innere Medizin (Heidelberg, Germany) Pub Date : 2025-02-01 Epub Date: 2025-01-20 DOI: 10.1007/s00108-024-01838-5
Sarah Fischer, Markus F Neurath
{"title":"[Update on the pathophysiology, prediction and prevention of inflammatory bowel diseases].","authors":"Sarah Fischer, Markus F Neurath","doi":"10.1007/s00108-024-01838-5","DOIUrl":"10.1007/s00108-024-01838-5","url":null,"abstract":"<p><strong>Background: </strong>The pathophysiology of inflammatory bowel diseases is not fully understood. In a staged model by the European Crohn's and Colitis Organization (ECCO) regarding disease development, it is assumed that there is a population at risk for manifestation of disease following subtle changes over time.</p><p><strong>Objective: </strong>This work aims to summarize the current state of knowledge regarding the pathophysiology, prediction and prevention of chronic inflammatory bowel diseases.</p><p><strong>Materials and methods: </strong>Selective literature research via PubMed.</p><p><strong>Results: </strong>Several genetic, biochemical, and microbiome scores have the potential to identify individuals at increased risk of developing inflammatory bowel disease, possibly up to a decade before onset.</p><p><strong>Discussion: </strong>The growing knowledge regarding the pathogenesis of inflammatory bowel diseases makes prediction before disease onset a possible future diagnostic goal. Hypothetically, early changes before the disease manifests could be reversible and may be amenable to prevention programs.</p>","PeriodicalId":73385,"journal":{"name":"Innere Medizin (Heidelberg, Germany)","volume":" ","pages":"137-145"},"PeriodicalIF":0.0,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143017510","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Inflammatory bowel diseases-Part 2].
Innere Medizin (Heidelberg, Germany) Pub Date : 2025-02-01 Epub Date: 2025-02-05 DOI: 10.1007/s00108-024-01847-4
Benjamin Misselwitz, Helga P Török, Julia Mayerle
{"title":"[Inflammatory bowel diseases-Part 2].","authors":"Benjamin Misselwitz, Helga P Török, Julia Mayerle","doi":"10.1007/s00108-024-01847-4","DOIUrl":"https://doi.org/10.1007/s00108-024-01847-4","url":null,"abstract":"","PeriodicalId":73385,"journal":{"name":"Innere Medizin (Heidelberg, Germany)","volume":"66 2","pages":"135-136"},"PeriodicalIF":0.0,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143190466","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Wertvolle Versorgungsforschung.
Innere Medizin (Heidelberg, Germany) Pub Date : 2025-02-01 DOI: 10.1007/s00108-025-01848-x
{"title":"Wertvolle Versorgungsforschung.","authors":"","doi":"10.1007/s00108-025-01848-x","DOIUrl":"https://doi.org/10.1007/s00108-025-01848-x","url":null,"abstract":"","PeriodicalId":73385,"journal":{"name":"Innere Medizin (Heidelberg, Germany)","volume":"66 2","pages":"200-206"},"PeriodicalIF":0.0,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143191305","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[An update on surgical treatment options for inflammatory bowel disease].
Innere Medizin (Heidelberg, Germany) Pub Date : 2025-02-01 Epub Date: 2025-01-30 DOI: 10.1007/s00108-024-01846-5
Werner Kneist
{"title":"[An update on surgical treatment options for inflammatory bowel disease].","authors":"Werner Kneist","doi":"10.1007/s00108-024-01846-5","DOIUrl":"10.1007/s00108-024-01846-5","url":null,"abstract":"<p><p>There are national and international guidelines and developments for the surgery of chronic inflammatory bowel disease (IBD) that contribute to better patient care. Important recommendations include increasingly individualized and minimally invasive approaches with the integration of new technologies. The indication for abdominal surgery remains tied to specialization, not least in order to continue to be able to assess the importance of sequential treatment and multimodality in improving surgical results and minimizing risks. This paper aims to briefly present key surgical aspects and classify them according to the current state of knowledge.</p>","PeriodicalId":73385,"journal":{"name":"Innere Medizin (Heidelberg, Germany)","volume":" ","pages":"174-180"},"PeriodicalIF":0.0,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11799054/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143070016","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Chronic back pain-pharmacological and nonpharmacological treatment approaches]. [慢性背痛--药物和非药物治疗方法]。
Innere Medizin (Heidelberg, Germany) Pub Date : 2025-02-01 Epub Date: 2025-01-15 DOI: 10.1007/s00108-024-01843-8
Stavros Oikonomidis, Maximillian Lenz, Philipp Egenolf, Peer Eysel
{"title":"[Chronic back pain-pharmacological and nonpharmacological treatment approaches].","authors":"Stavros Oikonomidis, Maximillian Lenz, Philipp Egenolf, Peer Eysel","doi":"10.1007/s00108-024-01843-8","DOIUrl":"10.1007/s00108-024-01843-8","url":null,"abstract":"<p><p>Chronic back pain is a global health problem with significant impacts on physical and mental health, work ability, and quality of life. Back pain has an increased risk of becoming chronic, especially in patients with other chronic conditions. Treatment primarily focuses on nonpharmacological approaches. Regular exercise is strongly recommended for pain relief and improved function. Physical therapy can provide guidance and education on appropriate exercises. Acupuncture may offer some pain relief, but the evidence is inconclusive. Pharmacological treatments include nonsteroidal anti-inflammatory drugs (NSAIDs), muscle relaxants, and opioids. While NSAIDs can provide short-term relief, long-term use is associated with side effects. Muscle relaxants are not recommended for chronic pain. Opioids can be effective for severe pain but carry a risk of addiction and should be used with caution. Facet joint injections can provide temporary relief for some patients. Surgery may be considered when there is a clear correlation between structural abnormalities and symptoms. However, the relationship between degenerative changes and pain is complex and not fully understood. The management of chronic back pain often requires a multidisciplinary approach. Nonpharmacological interventions should be the first line of treatment. Pharmacological agents can provide temporary relief. Regular follow-up by healthcare professionals is crucial for optimal management.</p>","PeriodicalId":73385,"journal":{"name":"Innere Medizin (Heidelberg, Germany)","volume":" ","pages":"225-230"},"PeriodicalIF":0.0,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142985625","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Hepatotoxicity due to albendazole: safe alternatives for echinococcosis therapy]. [阿苯达唑引起的肝毒性：治疗棘球蚴病的安全替代方案]。
Innere Medizin (Heidelberg, Germany) Pub Date : 2025-02-01 Epub Date: 2024-09-23 DOI: 10.1007/s00108-024-01796-y
Laura Muana Wilhelm, Joschka Bachmann, Markus Cornberg, Heiner Wedemeyer, Bernd Heinrich
{"title":"[Hepatotoxicity due to albendazole: safe alternatives for echinococcosis therapy].","authors":"Laura Muana Wilhelm, Joschka Bachmann, Markus Cornberg, Heiner Wedemeyer, Bernd Heinrich","doi":"10.1007/s00108-024-01796-y","DOIUrl":"10.1007/s00108-024-01796-y","url":null,"abstract":"<p><p>Infection with Echinococcus multilocularis leads to the clinical manifestation of alveolar echinococcosis. This is characterized by the formation of alveolar liver tumours, which usually disintegrate necrotically in the course of the disease. Pseudocysts are formed. Especially in the early stages, curative resection followed by long-term treatment with albendazole is recommended. However, the majority of patients are not amenable to curative surgery. In these cases, albendazole therapy is the first-choice treatment. We present a rare case of albendazole-associated hepatitis in a patient with inoperable Echinococcus multilocularis infection, with a favourable outcome following a change in treatment to mebendazole.</p>","PeriodicalId":73385,"journal":{"name":"Innere Medizin (Heidelberg, Germany)","volume":" ","pages":"231-235"},"PeriodicalIF":0.0,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11799110/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142309275","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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