{"title":"[Artificial intelligence in internal medicine exemplified by cardiology].","authors":"Henrike A K Hillmann, Amalia Sluha, David Duncker","doi":"10.1007/s00108-026-02121-5","DOIUrl":"https://doi.org/10.1007/s00108-026-02121-5","url":null,"abstract":"<p><p>Artificial intelligence (AI) is gaining importance in the field of cardiology. By analyzing complex multimodal data AI can support the diagnostic processes, risk stratification and making decisions. In cardiac imaging AI-based procedures improve the objective image analysis and facilitate the detection of specific cardiac diseases. The AI-assisted analysis in electrocardiography (ECG) not only enables reliable identification of established diagnoses but also enables the detection of patterns not yet identifiable for the human eye and therefore opens up opportunities for the establishment of new diagnostics and risk stratification. Large language models (LLM) represent a subdomain of AI. In cardiology they show particular potential for knowledge-based and text-based tasks, such as clinical documentation, support in drafting medical reports and patient education. Based on the current evidence, publicly available LLM are not appropriate for image interpretation, clinical decision-making or for supporting peer-review processes. Key challenges for the clinical implementation of AI include data protection and data security, regulatory requirements, currently limited evidence from randomized clinical trials, the limited option for validation of self-learning algorithms, limited transparency and the need for structured training programs for both physicians and patients. Irrespective of the degree of AI assistance, physician oversight remains crucial.</p>","PeriodicalId":73385,"journal":{"name":"Innere Medizin (Heidelberg, Germany)","volume":" ","pages":""},"PeriodicalIF":0.6,"publicationDate":"2026-04-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147791049","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Hendrik Pott, Bernd Schmeck, Peter Alter, Gernot Rohde
{"title":"[Management of patients with chronic obstructive pulmonary disease in routine clinical practice].","authors":"Hendrik Pott, Bernd Schmeck, Peter Alter, Gernot Rohde","doi":"10.1007/s00108-026-02111-7","DOIUrl":"https://doi.org/10.1007/s00108-026-02111-7","url":null,"abstract":"<p><p>Chronic obstructive pulmonary disease (COPD) is among the leading causes of death worldwide and is characterized by chronic respiratory symptoms, persistent airflow limitation, and exacerbations. Diagnosis is confirmed by post-bronchodilator spirometry. Effective long-term management requires a structured assessment of relevant exposures, symptom burden, exacerbation history, and comorbidities. Key goals of treatment include reducing both symptom and disease burden and preventing future exacerbations, which are often associated with increased lung function decline. This article summarizes practical concepts for diagnostic work-up and therapeutic decision-making at the time of diagnosis, during follow-up, in acute exacerbations, and in the context of palliative care. It highlights individualized inhaled therapy, guided by symptoms, exacerbations, and blood eosinophil counts, as well as evidence-based non-pharmacological interventions such as smoking cessation, pulmonary rehabilitation, long-term oxygen therapy/non-invasive ventilation, and lung volume reduction strategies.</p>","PeriodicalId":73385,"journal":{"name":"Innere Medizin (Heidelberg, Germany)","volume":" ","pages":""},"PeriodicalIF":0.6,"publicationDate":"2026-04-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147730824","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Paradigmenwechsel in der Inneren Medizin – die Zukunft gestalten! : Die Innere Medizin als „Zukunftsmotor“.","authors":"Dagmar Führer-Sakel","doi":"10.1007/s00108-026-02091-8","DOIUrl":"https://doi.org/10.1007/s00108-026-02091-8","url":null,"abstract":"","PeriodicalId":73385,"journal":{"name":"Innere Medizin (Heidelberg, Germany)","volume":"67 4","pages":"367-370"},"PeriodicalIF":0.6,"publicationDate":"2026-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147517152","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Anna-Lena Farwick, Mustafa Bačinović, Oleg Heizmann, Achim Meinhardt
{"title":"[Two cases of complicated primary hyperparathyroidism during pregnancy].","authors":"Anna-Lena Farwick, Mustafa Bačinović, Oleg Heizmann, Achim Meinhardt","doi":"10.1007/s00108-025-02011-2","DOIUrl":"10.1007/s00108-025-02011-2","url":null,"abstract":"<p><p>We report two cases of primary hyperparathyroidism first diagnosed during pregnancy due to severe complications of hypercalcemia. Imaging revealed parathyroid adenomas, which were surgically removed. Early interdisciplinary diagnosis and management are essential to reduce maternal and fetal risks and ensure favorable outcomes.</p>","PeriodicalId":73385,"journal":{"name":"Innere Medizin (Heidelberg, Germany)","volume":" ","pages":"467-471"},"PeriodicalIF":0.6,"publicationDate":"2026-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145276688","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Petra Lynen Jansen, Patrick Michl, Thomas Rösch, Thomas Seufferlein, Britta Siegmund, Frank Tacke, Heiner Wedemeyer
{"title":"[The gut is where health begins : How gastroenterological diseases can be prevented].","authors":"Petra Lynen Jansen, Patrick Michl, Thomas Rösch, Thomas Seufferlein, Britta Siegmund, Frank Tacke, Heiner Wedemeyer","doi":"10.1007/s00108-026-02085-6","DOIUrl":"10.1007/s00108-026-02085-6","url":null,"abstract":"<p><p>Diseases of the digestive organs are among the most frequent diseases and at the same time diseases with the most severe consequences in Germany. They are widespread diseases in the proper sense. Around 2.5 million people are hospitalized annually due to gastroenterological diseases and approximately 140,000 deaths per year are directly attributed to them. In addition, there are substantial impairments in the quality of life, high periods of inability to work and an immense economic burden on the healthcare system with annual costs of over €60 billion. It is particularly relevant that a substantial proportion of these diseases could be avoided or at least the course could be favorably influenced. The gastrointestinal tract including the liver and pancreas undertakes a key management function for the whole organism. Disorders of the digestive organs not only have a local effect but also influence the metabolism, cardiovascular system, immune system and the brain. Therefore, prevention in gastroenterology always also means prevention of systemic diseases. A healthy gut is a prerequisite for a healthy life. Prevention in gastroenterology is also a success story. The introduction of screening coloscopy, the vaccination against hepatitis B, the introduction of hepatitis B and C screening and the eradication of Helicobacter pylori demonstrably reduce the morbidity and mortality risks and impressively show the potential of a consistently implemented preventive strategy. This article compiles the aims, evidence, success and current deficits in gastroenterological preventive measures, names potential improvements and provides a perspective of future developments.</p>","PeriodicalId":73385,"journal":{"name":"Innere Medizin (Heidelberg, Germany)","volume":" ","pages":"57-61"},"PeriodicalIF":0.6,"publicationDate":"2026-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147446110","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"[Clinician and medical scientists in internal medicine: endocrinology and immunology].","authors":"Christina Wenzek","doi":"10.1007/s00108-026-02082-9","DOIUrl":"10.1007/s00108-026-02082-9","url":null,"abstract":"","PeriodicalId":73385,"journal":{"name":"Innere Medizin (Heidelberg, Germany)","volume":" ","pages":"411-414"},"PeriodicalIF":0.6,"publicationDate":"2026-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147328449","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"[Clinician and medical scientists in internal medicine: cardiology].","authors":"Ann-Kathrin Rahm","doi":"10.1007/s00108-026-02079-4","DOIUrl":"10.1007/s00108-026-02079-4","url":null,"abstract":"","PeriodicalId":73385,"journal":{"name":"Innere Medizin (Heidelberg, Germany)","volume":" ","pages":"404-406"},"PeriodicalIF":0.6,"publicationDate":"2026-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147476549","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"[Design of early detection programs by the Federal Joint Committee].","authors":"Daniel Reuter, Bernhard van Treeck","doi":"10.1007/s00108-026-02074-9","DOIUrl":"10.1007/s00108-026-02074-9","url":null,"abstract":"<p><p>Early detection examinations are basic services covered by the statutory health insurance. They serve to identify severe, treatable diseases at an early stage. In Germany, the Federal Joint Committee plays a key role in this context: it uses evidence-based criteria to determine which examinations are part of standard care, under what conditions and how quality is ensured. The range of services is broad and includes prenatal care, neonatal screening, examinations in childhood and adolescence, general health examinations and early cancer detection. This article explains the current system and describes how it is continuously adapted to the latest medical findings. Benefit-risk assessments, guidelines from professional associations, hearings and consultation procedures and legislative initiatives shape the further development. When explaining reform options, particular attention is paid to the obstacles posed by current data protection regulations in the evaluation of programs.</p>","PeriodicalId":73385,"journal":{"name":"Innere Medizin (Heidelberg, Germany)","volume":" ","pages":"3-6"},"PeriodicalIF":0.6,"publicationDate":"2026-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147438142","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
M Vehreschild, K de With, E Kramme, C Lehmann, J Schelling, C Schenkel-Häger, G Fätkenheuer
{"title":"[Prevention of infectious diseases : The role of infectious disease specialists].","authors":"M Vehreschild, K de With, E Kramme, C Lehmann, J Schelling, C Schenkel-Häger, G Fätkenheuer","doi":"10.1007/s00108-026-02071-y","DOIUrl":"10.1007/s00108-026-02071-y","url":null,"abstract":"<p><strong>Background: </strong>Infectious diseases are among the most frequent diseases encountered in both inpatient and outpatient settings. Therefore, the prevention of infections is a central task for physicians across all medical specialties.</p><p><strong>Objectives: </strong>This article discusses various areas of prevention and highlights the pivotal role of infectious disease specialists.</p><p><strong>Results: </strong>Vaccines are among the most effective measures for disease prevention overall. They are used in primary as well as for secondary prevention; however, to achieve the preventive targets an improvement in the vaccination rates in Germany is urgently necessary. To increase vaccine utilization, improvements in the intersectoral and interdisciplinary cooperation of various medical disciplines are of major importance. For prevention of the further spread of antimicrobial resistance, antimicrobial stewardship (AMS) teams have successfully been established in hospitals and AMS should also increasingly play a role in outpatient care. Another major task of prevention is the avoidance of nosocomial infections.</p><p><strong>Conclusion: </strong>The frequency as well as the medical and social impact of infectious diseases in healthcare clearly demonstrate the importance of prevention in this field. Improvements in provision of care are necessary at various levels with a focus on intersectoral and interdisciplinary cooperation of the medical disciplines. Infectious disease specialists should play a key role in coordinating these initiatives.</p>","PeriodicalId":73385,"journal":{"name":"Innere Medizin (Heidelberg, Germany)","volume":" ","pages":"26-29"},"PeriodicalIF":0.6,"publicationDate":"2026-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147357901","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}