Jan-Niklas Krohn, Christina Bermel, David Nisenbaum, Stefan Knop
{"title":"[Hemodynamically relevant cardiac relapse of diffuse large B-cell lymphoma].","authors":"Jan-Niklas Krohn, Christina Bermel, David Nisenbaum, Stefan Knop","doi":"10.1007/s00108-025-01937-x","DOIUrl":null,"url":null,"abstract":"<p><p>A 55-year-old female patient presented with a 1-week history of cough, dyspnea, pre-syncopal sensation and a history of asthma and long-lasting complete remission of diffuse large B‑cell lymphoma (LBCL). Imaging revealed a mass measuring 8 × 6.4 × 6.2 cm in the right ventricle and atrium, partially obstructing the cardiac valve plane. Biopsy was performed. With the onset of hemodynamic instability, ex juvantibus antineoplastic therapy was administered. After 36 h, echocardiography already showed a considerable size reduction to approximately 5 × 5 cm. Histology was consistent with relapsed LBCL. Staging showed no further manifestations and salvage therapy was initiated.</p>","PeriodicalId":73385,"journal":{"name":"Innere Medizin (Heidelberg, Germany)","volume":" ","pages":""},"PeriodicalIF":0.0000,"publicationDate":"2025-06-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Innere Medizin (Heidelberg, Germany)","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1007/s00108-025-01937-x","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 0
Abstract
A 55-year-old female patient presented with a 1-week history of cough, dyspnea, pre-syncopal sensation and a history of asthma and long-lasting complete remission of diffuse large B‑cell lymphoma (LBCL). Imaging revealed a mass measuring 8 × 6.4 × 6.2 cm in the right ventricle and atrium, partially obstructing the cardiac valve plane. Biopsy was performed. With the onset of hemodynamic instability, ex juvantibus antineoplastic therapy was administered. After 36 h, echocardiography already showed a considerable size reduction to approximately 5 × 5 cm. Histology was consistent with relapsed LBCL. Staging showed no further manifestations and salvage therapy was initiated.
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