Immunology todayPub Date : 2000-11-01DOI: 10.1016/S0167-5699(00)01747-3
Adam P Kohm , Virginia M Sanders
{"title":"Norepinephrine: a messenger from the brain to the immune system","authors":"Adam P Kohm , Virginia M Sanders","doi":"10.1016/S0167-5699(00)01747-3","DOIUrl":"10.1016/S0167-5699(00)01747-3","url":null,"abstract":"<div><p>A common dogma has been that norepinephrine (NE) suppresses lymphocyte function. However, recent studies have challenged this dogma, showing that NE also enhances immune cell readiness during infection and immune challenge.</p></div>","PeriodicalId":73346,"journal":{"name":"Immunology today","volume":"21 11","pages":"Pages 539-542"},"PeriodicalIF":0.0,"publicationDate":"2000-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/S0167-5699(00)01747-3","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"21920017","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Immunology todayPub Date : 2000-11-01DOI: 10.1016/S0167-5699(00)01746-1
Mauro M. Teixeira , Rodrigo Correa-Oliveira , Ricardo T. Gazzinelli
{"title":"Immunoregulation in parasitic infection: insights for therapeutic intervention","authors":"Mauro M. Teixeira , Rodrigo Correa-Oliveira , Ricardo T. Gazzinelli","doi":"10.1016/S0167-5699(00)01746-1","DOIUrl":"10.1016/S0167-5699(00)01746-1","url":null,"abstract":"<div><p>The diverse molecular and cellular mechanisms that regulate the immune response during infectious disease were discussed at a recent meeting<span><sup>*</sup></span>. Research in this area should provide novel therapeutic strategies for enhancing immunoprotective host responses or controlling deleterious parasite-elicited immunopathology.</p></div>","PeriodicalId":73346,"journal":{"name":"Immunology today","volume":"21 11","pages":"Pages 536-538"},"PeriodicalIF":0.0,"publicationDate":"2000-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/S0167-5699(00)01746-1","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"85550741","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Immunology todayPub Date : 2000-11-01DOI: 10.1016/S0167-5699(00)01748-5
Dimitrios Balomenos , Carlos Martı́nez-A
{"title":"Cell-cycle regulation in immunity, tolerance and autoimmunity","authors":"Dimitrios Balomenos , Carlos Martı́nez-A","doi":"10.1016/S0167-5699(00)01748-5","DOIUrl":"10.1016/S0167-5699(00)01748-5","url":null,"abstract":"<div><p>To trigger an effective immune response, lymphocytes must proliferate. In addition to their direct involvement in cell-cycle progression, cell-cycle regulators might thus control immune functions. Recent evidence suggests that these regulators are essential for T-cell function; we argue that their study will provide clues for dissecting anergy and tolerance mechanisms, as well as for intervention in autoimmune diseases.</p></div>","PeriodicalId":73346,"journal":{"name":"Immunology today","volume":"21 11","pages":"Pages 551-555"},"PeriodicalIF":0.0,"publicationDate":"2000-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/S0167-5699(00)01748-5","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"21918705","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Immunology todayPub Date : 2000-11-01DOI: 10.1016/S0167-5699(00)01763-1
Stephan Grabbe
{"title":"Access denied – competition for APC space among T cells","authors":"Stephan Grabbe","doi":"10.1016/S0167-5699(00)01763-1","DOIUrl":"10.1016/S0167-5699(00)01763-1","url":null,"abstract":"","PeriodicalId":73346,"journal":{"name":"Immunology today","volume":"21 11","pages":"Page 529"},"PeriodicalIF":0.0,"publicationDate":"2000-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/S0167-5699(00)01763-1","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"21920007","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Immunology todayPub Date : 2000-11-01DOI: 10.1016/S0167-5699(00)01735-7
Dale I. Godfrey , Kirsten J.L. Hammond , Lynn D. Poulton , Mark J. Smyth , Alan G. Baxter
{"title":"NKT cells: facts, functions and fallacies","authors":"Dale I. Godfrey , Kirsten J.L. Hammond , Lynn D. Poulton , Mark J. Smyth , Alan G. Baxter","doi":"10.1016/S0167-5699(00)01735-7","DOIUrl":"10.1016/S0167-5699(00)01735-7","url":null,"abstract":"<div><p>The proposed roles of NK1.1<sup>+</sup> T (NKT) cells in immune responses range from suppression of autoimmunity to tumor rejection. Heterogeneity of these cells contributes to the controversy surrounding their development and function. This review aims to provide an update on NKT cell biology and, whenever possible, to compare what is known about NKT-cell subsets.</p></div>","PeriodicalId":73346,"journal":{"name":"Immunology today","volume":"21 11","pages":"Pages 573-583"},"PeriodicalIF":0.0,"publicationDate":"2000-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/S0167-5699(00)01735-7","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"21918709","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Immunology todayPub Date : 2000-11-01DOI: 10.1016/S0167-5699(00)01767-9
Jennifer A Punt
{"title":"Life rafts for thymocytes","authors":"Jennifer A Punt","doi":"10.1016/S0167-5699(00)01767-9","DOIUrl":"10.1016/S0167-5699(00)01767-9","url":null,"abstract":"","PeriodicalId":73346,"journal":{"name":"Immunology today","volume":"21 11","pages":"Pages 530-531"},"PeriodicalIF":0.0,"publicationDate":"2000-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/S0167-5699(00)01767-9","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"21920013","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Immunology todayPub Date : 2000-11-01DOI: 10.1016/S0167-5699(00)01731-X
Lorenzo Moretta , Alessandro Moretta , Hans Hengartner , Rolf M Zinkernagel
{"title":"On the pathogenesis of perforin defects and related immunodeficiencies","authors":"Lorenzo Moretta , Alessandro Moretta , Hans Hengartner , Rolf M Zinkernagel","doi":"10.1016/S0167-5699(00)01731-X","DOIUrl":"10.1016/S0167-5699(00)01731-X","url":null,"abstract":"","PeriodicalId":73346,"journal":{"name":"Immunology today","volume":"21 11","pages":"Page 593"},"PeriodicalIF":0.0,"publicationDate":"2000-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/S0167-5699(00)01731-X","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"86926886","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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