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Human Monoclonal Antibodies 人单克隆抗体
Immunology today Pub Date : 2019-01-01 DOI: 10.1007/978-1-4939-8958-4
M. Steinitz
{"title":"Human Monoclonal Antibodies","authors":"M. Steinitz","doi":"10.1007/978-1-4939-8958-4","DOIUrl":"https://doi.org/10.1007/978-1-4939-8958-4","url":null,"abstract":"","PeriodicalId":73346,"journal":{"name":"Immunology today","volume":"44 1","pages":"113-7"},"PeriodicalIF":0.0,"publicationDate":"2019-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"79164653","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 5
Immunoreceptor Tyrosine-based Inhibition Motifs 基于酪氨酸的免疫受体抑制基序
Immunology today Pub Date : 2012-10-14 DOI: 10.1007/978-3-642-58537-1
Eric Vivier, M. Daëron
{"title":"Immunoreceptor Tyrosine-based Inhibition Motifs","authors":"Eric Vivier, M. Daëron","doi":"10.1007/978-3-642-58537-1","DOIUrl":"https://doi.org/10.1007/978-3-642-58537-1","url":null,"abstract":"","PeriodicalId":73346,"journal":{"name":"Immunology today","volume":"8 1","pages":"286-91"},"PeriodicalIF":0.0,"publicationDate":"2012-10-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"75592261","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 373
Immunology and Developmental Biology of the Chicken 鸡的免疫学和发育生物学
Immunology today Pub Date : 2011-12-08 DOI: 10.1007/978-3-642-80057-3
O. Vainio, B. Imhof
{"title":"Immunology and Developmental Biology of the Chicken","authors":"O. Vainio, B. Imhof","doi":"10.1007/978-3-642-80057-3","DOIUrl":"https://doi.org/10.1007/978-3-642-80057-3","url":null,"abstract":"","PeriodicalId":73346,"journal":{"name":"Immunology today","volume":"7 1","pages":"365-70"},"PeriodicalIF":0.0,"publicationDate":"2011-12-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"86036091","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 61
Immune Receptors 免疫受体
Immunology today Pub Date : 2011-01-01 DOI: 10.1007/978-1-61779-139-0
J. Rast
{"title":"Immune Receptors","authors":"J. Rast","doi":"10.1007/978-1-61779-139-0","DOIUrl":"https://doi.org/10.1007/978-1-61779-139-0","url":null,"abstract":"","PeriodicalId":73346,"journal":{"name":"Immunology today","volume":"13 1","pages":"1-29"},"PeriodicalIF":0.0,"publicationDate":"2011-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"88749514","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Helicobacter pylori vaccine strategies – triggering a gut reaction 幽门螺杆菌疫苗策略——引发肠道反应
Immunology today Pub Date : 2000-12-01 DOI: 10.1016/S0167-5699(00)01753-9
W.John W Morrow , Caterina Hatzifoti , Brendan W Wren
{"title":"Helicobacter pylori vaccine strategies – triggering a gut reaction","authors":"W.John W Morrow ,&nbsp;Caterina Hatzifoti ,&nbsp;Brendan W Wren","doi":"10.1016/S0167-5699(00)01753-9","DOIUrl":"10.1016/S0167-5699(00)01753-9","url":null,"abstract":"<div><p>Helicobacter pylori causes peptic ulcer disease and some forms of gastric cancer; it is one of the most common chronic bacterial infections of humans. Although several prototype protein-based vaccines have shown promising results, they have not cleared infection and/or prevented reinfection. Nucleic acid vaccination offers a useful alternative to protein immunization, especially now that two complete H. pylori genome sequences are available, and facilitates the selection of antigenic targets.</p></div>","PeriodicalId":73346,"journal":{"name":"Immunology today","volume":"21 12","pages":"Pages 615-619"},"PeriodicalIF":0.0,"publicationDate":"2000-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/S0167-5699(00)01753-9","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"21937347","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 28
Heparanase 2: a new insight into the mechanisms of cell trafficking? 肝素酶2:对细胞运输机制的新见解?
Immunology today Pub Date : 2000-12-01 DOI: 10.1016/S0167-5699(00)01771-0
Rebecca Lever
{"title":"Heparanase 2: a new insight into the mechanisms of cell trafficking?","authors":"Rebecca Lever","doi":"10.1016/S0167-5699(00)01771-0","DOIUrl":"10.1016/S0167-5699(00)01771-0","url":null,"abstract":"","PeriodicalId":73346,"journal":{"name":"Immunology today","volume":"21 12","pages":"Page 597"},"PeriodicalIF":0.0,"publicationDate":"2000-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/S0167-5699(00)01771-0","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"73537729","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Putting the rap on integrin activation 把重点放在整合素激活上
Immunology today Pub Date : 2000-12-01 DOI: 10.1016/S0167-5699(00)01783-7
Yoji Shimizu
{"title":"Putting the rap on integrin activation","authors":"Yoji Shimizu","doi":"10.1016/S0167-5699(00)01783-7","DOIUrl":"10.1016/S0167-5699(00)01783-7","url":null,"abstract":"","PeriodicalId":73346,"journal":{"name":"Immunology today","volume":"21 12","pages":"Page 597"},"PeriodicalIF":0.0,"publicationDate":"2000-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/S0167-5699(00)01783-7","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"21937343","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 9
How does TAP pump peptides? Insights from DNA repair and traffic ATPases TAP是如何泵送肽的?从DNA修复和交通atp酶的见解
Immunology today Pub Date : 2000-12-01 DOI: 10.1016/S0167-5699(00)01720-5
Eric A.J Reits, Alexander C Griekspoor, Jacques Neefjes
{"title":"How does TAP pump peptides? Insights from DNA repair and traffic ATPases","authors":"Eric A.J Reits,&nbsp;Alexander C Griekspoor,&nbsp;Jacques Neefjes","doi":"10.1016/S0167-5699(00)01720-5","DOIUrl":"10.1016/S0167-5699(00)01720-5","url":null,"abstract":"<div><p>This article presents an integral model of TAP function that visualizes how peptide and ATP drive the conformational changes required for pore opening and peptide transfer into the major histocompatibility complex (MHC) class I loading complex.</p></div>","PeriodicalId":73346,"journal":{"name":"Immunology today","volume":"21 12","pages":"Pages 598-600"},"PeriodicalIF":0.0,"publicationDate":"2000-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/S0167-5699(00)01720-5","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"21937344","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 31
The ITAM-bearing transmembrane adaptor DAP12 in lymphoid and myeloid cell function 含itam的跨膜接头DAP12在淋巴细胞和髓细胞功能中的作用
Immunology today Pub Date : 2000-12-01 DOI: 10.1016/S0167-5699(00)01745-X
Lewis L Lanier, Alexander B.H Bakker
{"title":"The ITAM-bearing transmembrane adaptor DAP12 in lymphoid and myeloid cell function","authors":"Lewis L Lanier,&nbsp;Alexander B.H Bakker","doi":"10.1016/S0167-5699(00)01745-X","DOIUrl":"10.1016/S0167-5699(00)01745-X","url":null,"abstract":"<div><p>DAP12, an ITAM-bearing transmembrane adaptor protein, associates non-covalently with receptors in natural killer (NK) and myeloid cells, and provides signaling function via the Syk and ZAP-70 tyrosine kinase activation pathways. Humans and mice lacking DAP12 (DAP12<sup>−/−</sup>) show normal development of hematopoietic cells. However, DAP12<sup>−/−</sup> humans develop presenile dementia and bone cysts, and DAP12<sup>−/−</sup> mice show impaired immune responses<em>.</em></p></div>","PeriodicalId":73346,"journal":{"name":"Immunology today","volume":"21 12","pages":"Pages 611-614"},"PeriodicalIF":0.0,"publicationDate":"2000-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/S0167-5699(00)01745-X","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"21937346","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 215
Molecular interactions of coreceptor CD8 and MHC class I: the molecular basis for functional coordination with the T-cell receptor 辅助受体CD8和MHC I类的分子相互作用:与t细胞受体功能协调的分子基础
Immunology today Pub Date : 2000-12-01 DOI: 10.1016/S0167-5699(00)01750-3
George F Gao , Bent K Jakobsen
{"title":"Molecular interactions of coreceptor CD8 and MHC class I: the molecular basis for functional coordination with the T-cell receptor","authors":"George F Gao ,&nbsp;Bent K Jakobsen","doi":"10.1016/S0167-5699(00)01750-3","DOIUrl":"10.1016/S0167-5699(00)01750-3","url":null,"abstract":"<div><p>In recent years, substantial progress has been made towards understanding the molecular basis for CD8 binding to class I MHC and the coreceptor's role in cytotoxic T-cell activation. Here, we review the structural, mechanistic and functional studies that point to a model of coordination of T-cell receptor and CD8 signaling that might provide the key to cytotoxic T-cell activation.</p></div>","PeriodicalId":73346,"journal":{"name":"Immunology today","volume":"21 12","pages":"Pages 630-636"},"PeriodicalIF":0.0,"publicationDate":"2000-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/S0167-5699(00)01750-3","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"21937350","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 159
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