IJID regions最新文献

筛选
英文 中文
Comment on “Agreement and systematic bias between QuantiFERON–chemiluminescent immunoassay and QuantiFERON-enzyme-linked immunosorbent assay in the detection of latent tuberculosis infection: a systematic review and meta-analysis” 对“quantiferon -化学发光免疫分析法与quantiferon -酶联免疫吸附法检测潜伏性结核感染的一致性和系统偏倚:系统综述和荟萃分析”的评论
IF 1.7
IJID regions Pub Date : 2026-03-01 Epub Date: 2026-02-07 DOI: 10.1016/j.ijregi.2026.100856
Xiaoshan Li , Li Zhang , Panfeng Shang
{"title":"Comment on “Agreement and systematic bias between QuantiFERON–chemiluminescent immunoassay and QuantiFERON-enzyme-linked immunosorbent assay in the detection of latent tuberculosis infection: a systematic review and meta-analysis”","authors":"Xiaoshan Li , Li Zhang , Panfeng Shang","doi":"10.1016/j.ijregi.2026.100856","DOIUrl":"10.1016/j.ijregi.2026.100856","url":null,"abstract":"","PeriodicalId":73335,"journal":{"name":"IJID regions","volume":"18 ","pages":"Article 100856"},"PeriodicalIF":1.7,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147538800","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Impact of pharmacist counseling intervention to improve health-related quality of life in pulmonary tuberculosis: a randomized controlled trial 药师咨询干预对改善肺结核患者健康相关生活质量的影响:一项随机对照试验
IF 1.7
IJID regions Pub Date : 2026-03-01 Epub Date: 2025-11-25 DOI: 10.1016/j.ijregi.2025.100810
Rabbiya Ahmad , Siti Maisharah Sheikh Ghadzi , Narendar Kumar , Syed Azhar Syed Sulaiman , Irfhan Ali Bin Hyder Ali , Fahad Hassan Baali , Abdulkarim Alshammari , Amer Hayat Khan
{"title":"Impact of pharmacist counseling intervention to improve health-related quality of life in pulmonary tuberculosis: a randomized controlled trial","authors":"Rabbiya Ahmad ,&nbsp;Siti Maisharah Sheikh Ghadzi ,&nbsp;Narendar Kumar ,&nbsp;Syed Azhar Syed Sulaiman ,&nbsp;Irfhan Ali Bin Hyder Ali ,&nbsp;Fahad Hassan Baali ,&nbsp;Abdulkarim Alshammari ,&nbsp;Amer Hayat Khan","doi":"10.1016/j.ijregi.2025.100810","DOIUrl":"10.1016/j.ijregi.2025.100810","url":null,"abstract":"<div><h3>Objectives</h3><div>Pulmonary tuberculosis (PTB) often leads to impaired health-related quality of life (HRQoL). The study evaluates the impact of a pharmacist-led educational counseling intervention on the HRQOL in individuals with PTB.</div></div><div><h3>Methods</h3><div>This single-blind, randomized controlled trial employed a parallel-group design at a tertiary care hospital in Malaysia. A total of 206 adults diagnosed with PTB were randomized (1:1) to receive either standard care under the directly observed therapy (DOT) strategy (control group) or DOT plus structured pharmacist-led counseling (intervention group) for 6 months. HRQoL was assessed at baseline and at treatment completion using the EQ-5D-3L and visual analog scale (VAS). Data analyses were performed using SPSS.</div></div><div><h3>Results</h3><div>There was a statistically significant difference between the control group and the intervention group on the quality-of-life scores post-intervention. Baseline HRQoL was comparable between groups (P &gt;0.05). At treatment completion, significant improvements were observed in the intervention group compared with the control group for self-care (P = 0.03), mobility (P = 0.05), and pain/discomfort (P = 0.01). Mean VAS scores were also higher in the intervention group (P &lt;0.001).</div></div><div><h3>Conclusions</h3><div>Pharmacist-led education and counseling interventions significantly improve the quality of life of patients with PTB.</div></div>","PeriodicalId":73335,"journal":{"name":"IJID regions","volume":"18 ","pages":"Article 100810"},"PeriodicalIF":1.7,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145791399","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Prevalence of Mycobacterium tuberculosis and risk factors among internally and externally displaced populations in northwestern Ethiopia: The case of Dabat and Metema 埃塞俄比亚西北部境内和境外流离失所人口中结核分枝杆菌的流行及其危险因素:Dabat和Metema的病例
IF 1.7
IJID regions Pub Date : 2026-03-01 Epub Date: 2025-12-30 DOI: 10.1016/j.ijregi.2025.100836
Deresse Daka , Belay Tessema , Awelani Mutshembele , Amir Alelign , Wubet Birhan , Baye Gelaw
{"title":"Prevalence of Mycobacterium tuberculosis and risk factors among internally and externally displaced populations in northwestern Ethiopia: The case of Dabat and Metema","authors":"Deresse Daka ,&nbsp;Belay Tessema ,&nbsp;Awelani Mutshembele ,&nbsp;Amir Alelign ,&nbsp;Wubet Birhan ,&nbsp;Baye Gelaw","doi":"10.1016/j.ijregi.2025.100836","DOIUrl":"10.1016/j.ijregi.2025.100836","url":null,"abstract":"<div><h3>Objectives</h3><div>Tuberculosis (TB) is a major global health crisis exacerbated by conflict and displacement. These factors disrupt health care and create overcrowded, unsanitary conditions that accelerate TB spread. This study investigated pulmonary TB epidemiology among refugees, internally displaced persons, and host communities in northwestern Ethiopia.</div></div><div><h3>Methods</h3><div>A multicenter cross-sectional study was conducted from July 1 to September 30, 2024 at Dabat and Metema refugee sites in northwestern Ethiopia. In this study, 1350 sputum samples were tested using GeneXpert MTB/RIF, with culture performed on Löwenstein–Jensen medium. Data were analyzed in IBM SPSS Statistics, Version 27 using logistic regression, with model fitness assessed to ensure reliable findings.</div></div><div><h3>Results</h3><div>Among 1350 study participants in northwestern Ethiopia, 56% were male, with a mean age of 35.29 years. The prevalence of Xpert MTB/RIF–confirmed TB was 102 cases (7.56%), of which 80 (78.4%) were culture-confirmed. Multivariable logistic regression identified several factors significantly associated with TB infection, such as cigarette smoking, recent TB contact, occupational exposure, diabetes, limited health care access, prolonged camp stay, alcohol consumption, biomass smoke exposure, weight loss, and shortness of breath.</div></div><div><h3>Conclusions</h3><div>This study demonstrated a high prevalence of <em>Mycobacterium tuberculosis</em> among conflict-affected displaced populations. Diabetes mellitus, smoking, recent TB contact, alcohol use, biomass smoke exposure, prolonged camp residence, and poor health care access were identified as significant risk factors.</div></div>","PeriodicalId":73335,"journal":{"name":"IJID regions","volume":"18 ","pages":"Article 100836"},"PeriodicalIF":1.7,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146077594","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Clinical approach to drug-resistant tuberculosis of the brain and spine in a low-income setting: A case series 低收入地区脑和脊柱耐药结核病的临床研究:一个病例系列
IF 1.7
IJID regions Pub Date : 2026-03-01 Epub Date: 2026-01-15 DOI: 10.1016/j.ijregi.2026.100847
Sohail Adnan, Farid Hussain, Sarfraz Khan
{"title":"Clinical approach to drug-resistant tuberculosis of the brain and spine in a low-income setting: A case series","authors":"Sohail Adnan,&nbsp;Farid Hussain,&nbsp;Sarfraz Khan","doi":"10.1016/j.ijregi.2026.100847","DOIUrl":"10.1016/j.ijregi.2026.100847","url":null,"abstract":"<div><h3>Background</h3><div>Drug-resistant tuberculosis (TB) of the brain and spine is difficult to sample for culture. It poses a significant challenge to physicians in low- and middle-income countries.</div></div><div><h3>Methods</h3><div>We present three patients of drug-resistant tuberculosis and demonstrate how we manage them in limited resources.</div></div><div><h3>Case Series</h3><div>Multi drug-resistant (MDR1): a young female patient had cerebellar tuberculomas at presentation. While being on conventional antituberculous therapy (ATT), she developed meningitis, and deteriorated with impaired conscious-level. Later, patient sustained ischemic strokes. Second-line ATT improved her condition. Treatment course was complicated by peripheral neuropathy, and psychotic behavior.</div><div>MDR2, a middle-aged woman having type-II diabetes was diagnosed with lumbar spondylitis. She was on conventional ATT for 1 year. Severe backache relapsed within a month of discontinuation of treatment. We started her on empirical second-line treatment. She had a dramatic response in pain and completely recovered at 1 year.</div><div>MDR3, a middle-aged woman had spondylitic changes at D10-D11 vertebral bodies on magnetic resonance imaging. The pain showed sub-optimum response to conventional ATT. The hyperintense signal changes resolved at 1 year of treatment with levofloxacin and linezolid.</div></div><div><h3>Conclusion</h3><div>These outcomes will raise physicians’ awareness of the need for early suspicion, and timely initiation of second-line therapy.</div></div>","PeriodicalId":73335,"journal":{"name":"IJID regions","volume":"18 ","pages":"Article 100847"},"PeriodicalIF":1.7,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147420615","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Prevalence and determinants of nasal carriage of methicillin-resistant Staphylococcus aureus among internally displaced persons in Mogadishu, Somalia: A community based cross-sectional study 索马里摩加迪沙境内流离失所者中耐甲氧西林金黄色葡萄球菌鼻腔携带的患病率和决定因素:一项基于社区的横断面研究
IF 1.7
IJID regions Pub Date : 2026-03-01 Epub Date: 2026-01-29 DOI: 10.1016/j.ijregi.2026.100851
Shafie Abdulkadir Hassan , Mowlid Abdikarin Mohamed , Abdifetah Ibrahim Omar
{"title":"Prevalence and determinants of nasal carriage of methicillin-resistant Staphylococcus aureus among internally displaced persons in Mogadishu, Somalia: A community based cross-sectional study","authors":"Shafie Abdulkadir Hassan ,&nbsp;Mowlid Abdikarin Mohamed ,&nbsp;Abdifetah Ibrahim Omar","doi":"10.1016/j.ijregi.2026.100851","DOIUrl":"10.1016/j.ijregi.2026.100851","url":null,"abstract":"<div><h3>Objectives</h3><div>Internal displacement creates complex health challenges, particularly regarding the spread of antimicrobial resistance (AMR). In Somalia, internally displaced persons (IDPs) reside in overcrowded settlements with limited sanitation, creating conditions that favor the transmission of methicillin-resistant <em>Staphylococcus aureus</em> (MRSA). While clinical infections are reported, community-based data on asymptomatic carriage is scarce. This study investigated the prevalence and predictors of nasal MRSA carriage among IDPs in Mogadishu.</div></div><div><h3>Methods</h3><div>A community-based cross-sectional study was conducted in the Daynile and Kahda districts of Mogadishu. A total of 428 IDPs were enrolled using systematic random sampling. Data on sociodemographics, housing, and medical history were collected via structured questionnaires. Anterior nasal swabs were cultured on Mannitol Salt Agar, and MRSA was confirmed using cefoxitin disk diffusion per Clinical &amp; Laboratory Standards Institute (CLSI) guidelines. Multivariable logistic regression was used to identify independent predictors of carriage.</div></div><div><h3>Results</h3><div>A total of 428 participants were enrolled (mean age 24.5 years). The overall prevalence of MRSA nasal carriage was 51.87% (222/428). In the multivariable analysis, the duration of displacement and household size were significant predictors of carriage. Recent arrival in the camp (1-15 months) was a strong risk factor (adjusted odds ratio = 2.92; 95% confidence interval: 1.64-5.19) compared to long-term residents. Additionally, smaller household sizes (1-4 members) showed higher odds of carriage (adjusted odds ratio = 2.08; 95% confidence interval: 1.23-3.51) compared to larger households, potentially reflecting specific housing vulnerabilities among newer, smaller family units.</div></div><div><h3>Conclusions</h3><div>The burden of MRSA carriage is exceptionally high among displaced populations in Mogadishu. The findings suggest that recent displacement and living conditions associated with newer arrivals are critical drivers of transmission. Public health interventions should target recent arrivals with improved shelter and hygiene promotion to mitigate the spread of resistant pathogens.</div></div>","PeriodicalId":73335,"journal":{"name":"IJID regions","volume":"18 ","pages":"Article 100851"},"PeriodicalIF":1.7,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147421066","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Epidemiology, clinical features, and outcomes of Mpox in children and adolescents in Uganda, August 2024–January 2025 2024年8月至2025年1月乌干达儿童和青少年麻疹的流行病学、临床特征和结果
IF 1.7
IJID regions Pub Date : 2026-03-01 Epub Date: 2026-01-07 DOI: 10.1016/j.ijregi.2026.100838
Charity Mutesi , Richard Migisha , Emmanuel Okiror Okello , Emmanuel Mfitundinda , Janet Kobusinge Lubega , Patrick Kwizera , Joanita Nalwanga , Hannington Katumba , Joyce Owens Kobusingye , Gertrude Abbo , Daniel Wenani , Bridget Ainembabazi , Olive Namakula Loryndah , Annet Namusisi , Lilian Bulage , Ivan Lukabwe , Dansan Atim , Alex Riolexus Ario
{"title":"Epidemiology, clinical features, and outcomes of Mpox in children and adolescents in Uganda, August 2024–January 2025","authors":"Charity Mutesi ,&nbsp;Richard Migisha ,&nbsp;Emmanuel Okiror Okello ,&nbsp;Emmanuel Mfitundinda ,&nbsp;Janet Kobusinge Lubega ,&nbsp;Patrick Kwizera ,&nbsp;Joanita Nalwanga ,&nbsp;Hannington Katumba ,&nbsp;Joyce Owens Kobusingye ,&nbsp;Gertrude Abbo ,&nbsp;Daniel Wenani ,&nbsp;Bridget Ainembabazi ,&nbsp;Olive Namakula Loryndah ,&nbsp;Annet Namusisi ,&nbsp;Lilian Bulage ,&nbsp;Ivan Lukabwe ,&nbsp;Dansan Atim ,&nbsp;Alex Riolexus Ario","doi":"10.1016/j.ijregi.2026.100838","DOIUrl":"10.1016/j.ijregi.2026.100838","url":null,"abstract":"<div><h3>Objectives</h3><div>Recent Mpox outbreaks in Uganda have primarily affected adults, but children and adolescents are at a higher risk of severe disease. We described the epidemiology, severity, and factors associated with severe Mpox among children and adolescents in Uganda during August 2024-January 2025.</div></div><div><h3>Methods</h3><div>We conducted a cross-sectional study among polymerase chain reaction-confirmed Mpox cases in patients aged 0-17 years in eight high-burden districts. Medical records were reviewed, and Mpox severity was measured using the severity scoring system. Participants’ variables were summarized using descriptive statistics and attack rates. Modified Poisson regression identified factors associated with severe disease.</div></div><div><h3>Results</h3><div>Among 160 case-patients, males (attack rate [AR] = 2.2/100,000) and females (AR = 2.1/100,000) were equally affected. Children &lt;5 years had the highest AR (3.7/100,000). Household (50%) and school (36%) exposures were most common. Overall, Mpox severity was 91% (adjusted prevalence ratio [aPR], 95% confidence interval: 87-96%). Care-seeking after 7 days from symptom onset was associated with higher severity (aPR: 1.1, 95% confidence interval: 1.03-1.3). Case fatality was 1.9%.</div></div><div><h3>Conclusions</h3><div>Children, especially those younger than 5, experienced high Mpox infection, often linked to household and school exposure. Care-seeking beyond 7 days increased disease severity. Interventions promoting early detection and timely care in households and schools could reduce Mpox-related morbidity and mortality in children and adolescents.</div></div>","PeriodicalId":73335,"journal":{"name":"IJID regions","volume":"18 ","pages":"Article 100838"},"PeriodicalIF":1.7,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146022412","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Determinants and regional inequalities in pregnancy deworming uptake in Somalia: findings from the 2020 Somalia demographic and health survey 索马里孕期驱虫吸收的决定因素和区域不平等:2020年索马里人口与健康调查结果
IF 1.7
IJID regions Pub Date : 2026-03-01 Epub Date: 2026-01-06 DOI: 10.1016/j.ijregi.2026.100841
Ahmed Saed Hussein , Ahmed Hassan Said , Mubarak Hassan Mohamud , Bashiir Abdirahman Guled , Sharif Abdi Mohamed , Ifrah Mukhtar Hussein
{"title":"Determinants and regional inequalities in pregnancy deworming uptake in Somalia: findings from the 2020 Somalia demographic and health survey","authors":"Ahmed Saed Hussein ,&nbsp;Ahmed Hassan Said ,&nbsp;Mubarak Hassan Mohamud ,&nbsp;Bashiir Abdirahman Guled ,&nbsp;Sharif Abdi Mohamed ,&nbsp;Ifrah Mukhtar Hussein","doi":"10.1016/j.ijregi.2026.100841","DOIUrl":"10.1016/j.ijregi.2026.100841","url":null,"abstract":"<div><h3>Objectives</h3><div>Soil-transmitted helminth (STH) infections remain widespread in Somalia, yet national evidence on deworming uptake during pregnancy is scarce. This study exams determinants and regional inequalities in pregnancy deworming uptake in Somalia: findings from the 2020 Somalia demographic and health survey (SDHS).</div></div><div><h3>Methods</h3><div>This study analyzed data from 14,419 women in the 2020 SDHS. Weighted descriptive statistics, bivariate analyses, and multivariate logistic regression were applied to identify determinants of deworming drug use. All analyses accounted for survey clustering, stratification, and sampling weights.</div></div><div><h3>Results</h3><div>National deworming coverage during pregnancy was 4.09%, among the lowest in sub-Saharan Africa. Uptake was significantly associated with antenatal care attendance (adjusted odds ratio [AOR] = 0.49), iron supplementation (AOR = 0.16), wealth (AOR = 1.81 among the richest), parity (AOR = 1.73), and maternal education (AOR = 1.72 for higher education). Marked geographic disparities were observed, with substantially higher odds in Lower Juba (AOR = 11.48), Bakool (AOR = 8.32), and Bay (AOR = 5.50) relative to Awdal. Nomadic women had increased odds of uptake (AOR = 6.01), while women in female-headed households were less likely to receive deworming (AOR = 0.86).</div></div><div><h3>Conclusions</h3><div>Deworming uptake in Somalia is critically low and shaped by socioeconomic and regional inequities, underscoring the need to improve antenatal care access and drug supply.</div></div>","PeriodicalId":73335,"journal":{"name":"IJID regions","volume":"18 ","pages":"Article 100841"},"PeriodicalIF":1.7,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146077595","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The prevalence of comorbidity among people living with HIV/AIDS in Guyana: a cross-sectional study 圭亚那艾滋病毒/艾滋病感染者合并症的流行:一项横断面研究
IF 1.7
IJID regions Pub Date : 2026-03-01 Epub Date: 2025-12-01 DOI: 10.1016/j.ijregi.2025.100820
Nneoma Harris , Ishaku Zechariah , Tariq Jagnarine
{"title":"The prevalence of comorbidity among people living with HIV/AIDS in Guyana: a cross-sectional study","authors":"Nneoma Harris ,&nbsp;Ishaku Zechariah ,&nbsp;Tariq Jagnarine","doi":"10.1016/j.ijregi.2025.100820","DOIUrl":"10.1016/j.ijregi.2025.100820","url":null,"abstract":"<div><h3>Objectives</h3><div>Comorbidities among people living with HIV/AIDS (PLHA) are increasing as life expectancy improves with antiretroviral therapy (ART). Understanding the prevalence and associated factors of these conditions in Guyana is essential for improving clinical outcomes. To evaluate the prevalence of comorbidities among PLHA in Guyana and to identify the most prevalent comorbidities and associated risk factors from January 2017 to December 2022.</div></div><div><h3>Methods</h3><div>A retrospective cross-sectional study was conducted using data from 1066 patients across 10 HIV care and treatment centers in regions 3, 4, and 10. Data were collected using a standardized tool, coded according to the International Classification of Diseases, 11th revision, and analyzed using SPSS.</div></div><div><h3>Results</h3><div>Overall, 57.2% had at least one comorbid condition, with hypertension (29.5%), obesity (12.8%), and diabetes mellitus type II (7.4%) being the most prevalent. Significant factors associated with comorbidity included age (<em>P</em> &lt; 0.001), ethnicity (<em>P</em> = 0.047), same-sex relations (<em>P</em> = 0.027), ART use (<em>P</em> &lt; 0.001), and adherence level (<em>P</em> &lt; 0.001).</div></div><div><h3>Conclusions</h3><div>Comorbidities are common among PLHA in Guyana and have important implications for HIV management. Recommendation: Implementation of routine screening and management protocols for common comorbidities in PLHA is crucial for improving patient care in Guyana.</div></div>","PeriodicalId":73335,"journal":{"name":"IJID regions","volume":"18 ","pages":"Article 100820"},"PeriodicalIF":1.7,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145840713","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Navigating Candidemia in a tertiary hospital: A 4-year epidemiologic and clinical review 三级医院念珠菌病的防治:4年流行病学和临床回顾
IF 1.7
IJID regions Pub Date : 2026-03-01 Epub Date: 2026-02-19 DOI: 10.1016/j.ijregi.2026.100864
Chadi Hage Chehade , Bassem Habr , Carine Harmouche , May Fakhoury , Nabil Chehata , Hassan Choker , Christian Haddad , Issam Daou , Zeina Bou Chebl , Racha Eid , Elie Haddad
{"title":"Navigating Candidemia in a tertiary hospital: A 4-year epidemiologic and clinical review","authors":"Chadi Hage Chehade ,&nbsp;Bassem Habr ,&nbsp;Carine Harmouche ,&nbsp;May Fakhoury ,&nbsp;Nabil Chehata ,&nbsp;Hassan Choker ,&nbsp;Christian Haddad ,&nbsp;Issam Daou ,&nbsp;Zeina Bou Chebl ,&nbsp;Racha Eid ,&nbsp;Elie Haddad","doi":"10.1016/j.ijregi.2026.100864","DOIUrl":"10.1016/j.ijregi.2026.100864","url":null,"abstract":"<div><h3>Objectives</h3><div>This study describes the epidemiology, risk factors, therapeutic management, antifungal resistance patterns, and clinical outcomes of candidemia in hospitalized patients. It also examines predictors of 30-day mortality and factors associated with <em>Candida albicans</em> (CA) vs non-<em>albicans Candida</em> (NCA) infections.</div></div><div><h3>Methods</h3><div>A retrospective review was conducted at a tertiary care center in Lebanon (2017-2021). Clinical, microbiological, and treatment data were extracted from medical records. Statistical analyses were performed to identify factors associated with 30-day mortality and the occurrence of CA vs NCA species.</div></div><div><h3>Results</h3><div>A total of 98 candidemia episodes in 93 patients were analyzed. CA and NCA species were equally represented (50% each). Resistance was highest to fluconazole and itraconazole (7.3%). The 30-day mortality rate was 38.8%. Factors significantly associated with increased mortality included intensive care unit admission (odds ratio [OR] 7.42), chronic renal failure (OR 7.29), dialysis (OR 7.28), mechanical ventilation (OR 4.71), and central venous catheters (OR 10.91). Catheter removal was protective (OR 0.205, <em>P</em> = 0.002). NCA infections were associated with dyslipidemia (OR 3.33) and multiple previous hospitalizations (OR 3.65).</div></div><div><h3>Conclusion</h3><div>Antifungal resistance remains relatively low in this cohort; however, candidemia continues to carry a high mortality rate. Optimizing management through adherence to international guidelines and specialist oversight is essential to improve outcomes and address the diverse clinical presentations of CA and NCA infections.</div></div>","PeriodicalId":73335,"journal":{"name":"IJID regions","volume":"18 ","pages":"Article 100864"},"PeriodicalIF":1.7,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147421067","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Response to the letter regarding Agreement and systematic bias between QuantiFERON chemiluminescent immunoassay and QuantiFERON enzyme-linked immunosorbent assay in the detection of latent tuberculosis infection: A systematic review and meta-analysis 对QuantiFERON化学发光免疫分析法和QuantiFERON酶联免疫吸附法检测潜伏性结核感染的一致性和系统偏倚的回复:系统回顾和荟萃分析
IF 1.7
IJID regions Pub Date : 2026-03-01 Epub Date: 2026-02-11 DOI: 10.1016/j.ijregi.2026.100855
Bwambale Jonani , Felix Bongomin
{"title":"Response to the letter regarding Agreement and systematic bias between QuantiFERON chemiluminescent immunoassay and QuantiFERON enzyme-linked immunosorbent assay in the detection of latent tuberculosis infection: A systematic review and meta-analysis","authors":"Bwambale Jonani ,&nbsp;Felix Bongomin","doi":"10.1016/j.ijregi.2026.100855","DOIUrl":"10.1016/j.ijregi.2026.100855","url":null,"abstract":"","PeriodicalId":73335,"journal":{"name":"IJID regions","volume":"18 ","pages":"Article 100855"},"PeriodicalIF":1.7,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147538801","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
0
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
确定
请完成安全验证×
相关产品
×
本文献相关产品
联系我们:info@booksci.cn Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。 Copyright © 2023 布克学术 All rights reserved.
京ICP备2023020795号-1
ghs 京公网安备 11010802042870号
Book学术文献互助
Book学术文献互助群
群 号:604180095
Book学术官方微信
小红书