IJID regions最新文献

{"title":"Prevalence and risk factors of intestinal schistosomiasis on students at Bochesa Elementary School, around the wetlands of Lake Ziway, Ethiopia","authors":"Ayalew Sisay","doi":"10.1016/j.ijregi.2025.100591","DOIUrl":"10.1016/j.ijregi.2025.100591","url":null,"abstract":"<div><h3>Objectives</h3><div>This study aimed to assess the prevalence and risk factors of intestinal schistosomiasis in students at Bochesa Elementary School in the wetlands of Lake Ziway.</div></div><div><h3>Methods</h3><div>A cross-sectional study of 384 students was conducted in May 2016. Intestinal schistosomiasis was examined using the Kato-Katz technique. For the association between the prevalence of intestinal schistosomiasis and categorical variables, the chi-square (χ²) test was used. A binary logistic regression was applied.</div></div><div><h3>Results</h3><div>The overall prevalence of intestinal schistosomiasis was 25.52%. Males were more infected (17.45%) than women (8.07%), and the difference was significant (χ² = 17.756; <em>P</em> &lt;0.05). Lower grade (1–4) students were more infected (20.83%) than grade 5-8 students (4.69%), and the difference was significant (χ² = 19.558; <em>P</em> &lt;0.05). Age groups of 7-14-year-old students were more infected (24.74%) than &gt;15-year-old students (0.78%), and the difference was significant (χ² = 4.788; <em>P</em> &lt;0.05).</div></div><div><h3>Conclusions</h3><div>The result implied that the wetlands of Lake Ziway are conducive to schistosomiasis. Students should receive health education on the mode of schistosomiasis transmission and its prevention methods, and a buffer zone for the wetlands should be identified. Praziquantel treatment is crucial in reducing intestinal schistosomiasis in students.</div></div>","PeriodicalId":73335,"journal":{"name":"IJID regions","volume":"14 ","pages":"Article 100591"},"PeriodicalIF":1.5,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143419496","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Crimean-Congo hemorrhagic fever, a real health problem in Iraq?","authors":"Masood Abdulkareem Abdulrahman","doi":"10.1016/j.ijregi.2025.100588","DOIUrl":"10.1016/j.ijregi.2025.100588","url":null,"abstract":"<div><h3>Objectives</h3><div>Crimean-Congo hemorrhagic fever (CCHF) is the most widespread tick-borne viral disease worldwide. CCHF was not recognized in Iraq before 1979, after which many outbreaks occurred, and the disease became endemic with the re-emergence of outbreaks. This study aimed to analyze the epidemiology of the largest outbreak in Iraqi history in 2023.</div></div><div><h3>Methods</h3><div>This retrospective study included human CCHF cases from 2023.</div></div><div><h3>Results</h3><div>2186 suspected cases were investigated. There were 587 confirmed cases, and 83 deaths, and an overall case fatality rate (14%). Among the confirmed cases, only 539 cases had complete data, and the analysis was performed on these cases. The majority 70.9% of patients lived in the southern provinces. Approximately 58% of the patients were male and up to half of the patients resided in rural areas. Approximately 45% of cases were in the 25-44 years age group. The occupations of the patients were as follows: 30% were housewives, 22% were butchers, 18% were animal owners, 30% had other occupations, and up to 60% had a history of exposure to fresh raw meat.</div></div><div><h3>Conclusions</h3><div>The 2023 outbreak was the largest in Iraq in decades. The absence of preventive and control activities during the COVID-19 pandemic played an important role in the rise of cases and the presence of unlicensed and freelance slaughterers, especially during religious events played an important role in this epidemic.</div></div>","PeriodicalId":73335,"journal":{"name":"IJID regions","volume":"14 ","pages":"Article 100588"},"PeriodicalIF":1.5,"publicationDate":"2025-01-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143419495","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Burden of rotavirus and other microorganisms in hospitalized children with acute gastroenteritis in Yangon, Myanmar, before the introduction of rotavirus vaccine","authors":"Tatsuki Ikuse ,&nbsp;Yuta Aizawa ,&nbsp;Kazuhiro Kamata ,&nbsp;Khin Nyo Thein ,&nbsp;Di Ja Lasham ,&nbsp;Su Sandar Tun ,&nbsp;Nay Chi Win ,&nbsp;Su Mon Kyaw Win ,&nbsp;Ai Ito ,&nbsp;Mon Mon ,&nbsp;Aye Thida ,&nbsp;Aye Aye Khin ,&nbsp;Yuki Higashimoto ,&nbsp;Tetsushi Yoshikawa ,&nbsp;Satoshi Komoto ,&nbsp;Hisami Watanabe ,&nbsp;Reiko Saito ,&nbsp;Akihiko Saitoh","doi":"10.1016/j.ijregi.2025.100589","DOIUrl":"10.1016/j.ijregi.2025.100589","url":null,"abstract":"<div><h3>Objectives</h3><div>In developing countries, acute gastroenteritis (AGE) is a leading cause of death in children younger than 5 years. In Myanmar, no comprehensive study has been done to investigate the microorganisms responsible for AGE among hospitalized children. Multiplex polymerase chain reaction (PCR) was used to identify the microorganisms responsible for AGE in children hospitalized in Myanmar before the introduction of the rotavirus vaccine.</div></div><div><h3>Methods</h3><div>This prospective study enrolled children younger than 12 years with AGE who were hospitalized at the Yankin Children's Hospital in Yangon, Myanmar, between September 2019 and February 2020. Multiplex PCR (FilmArray^TM GI panel, BioFire Diagnostics, Salt Lake City, USA) and genotyping with Sanger sequencing of rotavirus were performed. Clinical data, including disease severity, were collected from the medical records.</div></div><div><h3>Results</h3><div>We collected stool samples from 92 patients. Multiple microorganisms (median 3; interquartile range 2-4) were detected in 81 patients (88%). Rotavirus and norovirus were detected in 77 (84%) and 33 patients (36%), respectively. The most frequent bacterial pathogen detected was Enteroaggregative <em>E. coli</em> (n = 62/92, 67%). The most common rotavirus genotypes were G1P [<span><span>8</span></span>] (19/73; 26%) and G2P [<span><span>4</span></span>] (19/73; 26%).</div></div><div><h3>Conclusions</h3><div>Rotavirus is the predominant pathogen associated with AGE in hospitalized children in Myanmar. The introduction of a rotavirus vaccine will reduce the morbidity and mortality of children with rotavirus-associated AGE in Myanmar.</div></div>","PeriodicalId":73335,"journal":{"name":"IJID regions","volume":"14 ","pages":"Article 100589"},"PeriodicalIF":1.5,"publicationDate":"2025-01-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143455085","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Challenges in managing gestational malaria due to Plasmodium vivax with severe complications: A clinical case from Colombia","authors":"Catalina Tovar-Acero ,&nbsp;Carlos Alberto Bolívar Pineda ,&nbsp;Eliud Daniel Pérez Vergara ,&nbsp;Nohra Díaz Cornejo ,&nbsp;Dina Ricardo-Caldera","doi":"10.1016/j.ijregi.2025.100586","DOIUrl":"10.1016/j.ijregi.2025.100586","url":null,"abstract":"<div><div>Gestational malaria is a life-threatening disease that affects pregnant women in endemic regions. Infection with parasites of the genus Plasmodium, transmitted by infected mosquitoes, can trigger complications for the mother and fetus. We present the description of a clinical case of gestational malaria complicated by <em>Plasmodium vivax</em> in a 25-year-old multiparous patient in the third trimester of pregnancy from an endemic area in the department of Córdoba, Colombia. Admission to the intensive care unit for 3 days and an emergency cesarean section were necessary due to serious complications, such as anemia, severe thrombocytopenia, and hypertensive symptoms. Treatment included the use of chloroquine and red blood cell and platelet transfusions to address hematologic complications. After the cesarean section, the patient made a satisfactory recovery and was prescribed primaquine for 14 days. The importance of surveillance and adequate management of gestational malaria is highlighted to prevent serious complications during pregnancy and in the postpartum period. This clinical case highlights the complexity of gestational malaria and the need for a comprehensive approach to its management, with special attention to hematologic, hypertensive, and obstetric complications that may arise in this clinical context.</div></div>","PeriodicalId":73335,"journal":{"name":"IJID regions","volume":"14 ","pages":"Article 100586"},"PeriodicalIF":1.5,"publicationDate":"2025-01-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143349109","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Severe dengue–related deaths in the elderly population soared in Southern Brazil in 2024","authors":"Alexandre Sarmento Queiroga ,&nbsp;Danielly Alves Mendes Barbosa ,&nbsp;Tulio de Lima Campos ,&nbsp;Alexandre Vargas Schwarzbold ,&nbsp;Andre M. Siqueira ,&nbsp;Richard Steiner Salvato ,&nbsp;Gabriel Luz Wallau","doi":"10.1016/j.ijregi.2025.100577","DOIUrl":"10.1016/j.ijregi.2025.100577","url":null,"abstract":"<div><h3>Introduction</h3><div>Dengue fever is expanding worldwide on the track of climate change. In 2024, more than 14 million cases were reported. Around 6.5 million of those were reported in Brazil alone, reaching a staggering number of around 6000 deaths. Dengue lethality in severe cases were particularly high in Rio Grande do Sul, a historically less affected state which has witnessed an increased incidence and outbreaks in the last 4 years.</div></div><div><h3>Design</h3><div>In this report, we raised some hypotheses to explain the high lethality.</div></div><div><h3>Results</h3><div>Rio Grande do Sul has the highest proportion of elderly individuals among all states in Brazil. This factor, associated with the immunologically naive population, low levels of awareness to detect and treat severe dengue, and the difficulties in managing elderly patients, may have contributed to this higher lethality in severe dengue.</div></div><div><h3>Conclusions</h3><div>The expected increasing dengue incidence in the region in the subsequent years highlights the urgent need of an integrated approach to raise awareness, reduce mosquito populations, and reduce dengue burden in the region, particularly, in the most vulnerable elderly population.</div></div>","PeriodicalId":73335,"journal":{"name":"IJID regions","volume":"14 ","pages":"Article 100577"},"PeriodicalIF":1.5,"publicationDate":"2025-01-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143378596","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Factors predictive of epidemic waves of COVID-19 in Africa during the first 2 years of the pandemic","authors":"Patient Wimba ,&nbsp;Aboubacar Diallo ,&nbsp;Amna Klich ,&nbsp;Léon Tshilolo ,&nbsp;Jean Iwaz ,&nbsp;Jean François Étard ,&nbsp;Philippe Vanhems ,&nbsp;René Ecochard ,&nbsp;Muriel Rabilloud","doi":"10.1016/j.ijregi.2025.100574","DOIUrl":"10.1016/j.ijregi.2025.100574","url":null,"abstract":"<div><h3>Objectives</h3><div>The objective was to study the epidemic wave curves, according to the characteristics of the countries, to identify the differences and the predictive factors of evolution.</div></div><div><h3>Methods</h3><div>We have carried out modeling of the COVID-19 epidemic data from validated databases for 53 African countries.</div></div><div><h3>Results</h3><div>All countries recorded at least four waves. The duration of the waves had decreased over time (<em>P</em> &lt;0.001) and extended with the rainy season (<em>P</em> = 0.03). The incidence rates were higher for countries with the best development indicators (<em>P</em> &lt;0.001). Positive spatial autocorrelation was significant for all wave characteristics, except for relative amplitude at the end of the wave. The time-adjusted multivariate analysis identified seasons for duration (<em>P</em> = 0.017) and human development index for peak incidence rate (<em>P</em> &lt;0.001) and relative amplitude at the end of the wave (<em>P</em> = 0.041) as predictors of wave characteristics.</div></div><div><h3>Conclusions</h3><div>The duration of the waves was influenced by the seasons and the study periods, the incidences by the economic development, and health indicators. The appearance of new variants seemed associated with the start of the waves. None of the factors studied is associated with an inflection and a decrease in the curve.</div></div>","PeriodicalId":73335,"journal":{"name":"IJID regions","volume":"14 ","pages":"Article 100574"},"PeriodicalIF":1.5,"publicationDate":"2025-01-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143403511","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"HIV incidence and adherence after pre-exposure prophylaxis initiation in key populations in Indonesia: Findings from a real-world pilot program 2021-2023","authors":"Nadia Hanum ,&nbsp;Miasari Handayani ,&nbsp;Armina Padmasawitri ,&nbsp;Zulfan Zazuli ,&nbsp;Kusnandar Anggadiredja ,&nbsp;Mawar N. Pohan ,&nbsp;Tarinanda A. Putri ,&nbsp;Fani F. Rakhmat ,&nbsp;Dwi S. Anggiani ,&nbsp;Nurhalina Afriana ,&nbsp;Endang Lukitosari ,&nbsp;Bagus R. Prabowo ,&nbsp;Rudi Wisaksana","doi":"10.1016/j.ijregi.2025.100573","DOIUrl":"10.1016/j.ijregi.2025.100573","url":null,"abstract":"<div><h3>Objectives</h3><div>To provide important data for the national rollout, Indonesia launched a pre-exposure prophylaxis (PrEP) pilot program. In this study, we determined the HIV incidence and adherence among key populations, PrEP initiation, sexually transmitted infection incidence, and changes in sexual behaviors.</div></div><div><h3>Methods</h3><div>The Indonesian PrEP pilot program (December 2021 to December 2023, rolled out in 21 districts in 10 provinces) was a longitudinal, non-randomized implementation study among men who have sex with men, female sex workers, transgender women, people who inject drugs, and serodiscordant partners of people with HIV. Eligible participants were offered same-day oral PrEP and completed the baseline, 1-monthly, and 3-monthly follow-up visits.</div></div><div><h3>Results</h3><div>A total of 9124 individuals initiated PrEP between December 2021 and December 2023; 4220 had at least one follow-up visit. Of the 4220, 31 seroconverted over 2817.5 person-years; overall incidence rate (IR) 1.10 (95% confidence interval 0.75-1.56) per 100 person-years. All seroconversions occurred during poor adherence or PrEP discontinuation (IR 7.8; 5.34-11.16 vs 0; 0-0.4 for adequate adherence). Event-driven PrEP users showed poorer adherence than daily PrEP users (<em>P &lt;</em>0.001). In men who have sex with men, HIV incidence was higher in those who lived outside Java and Bali (adjusted IR ratio 5.56; 1.68-18.38, <em>P</em> = 0.005).</div></div><div><h3>Conclusion</h3><div>Insufficient adherence leads to decreased efficacy of PrEP. Improving adherence and access to PrEP is a public health priority in Indonesia.</div></div>","PeriodicalId":73335,"journal":{"name":"IJID regions","volume":"14 ","pages":"Article 100573"},"PeriodicalIF":1.5,"publicationDate":"2025-01-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143313003","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The vaccination acceptance, confidence, and conviction on influenza in the Middle East, Eurasia, and Africa among healthcare providers (VACCIMENA-HCP) project 2023: Determinants of vaccination behavior","authors":"Mine Durusu Tanriover ,&nbsp;Gaelle Vallee-Tourangeau ,&nbsp;Valentin A. Kokorin ,&nbsp;Vera N. Larina ,&nbsp;Mouna Maamar ,&nbsp;Hicham Harmouche ,&nbsp;Oğuz Abdullah Uyaroğlu ,&nbsp;Dilan Yağmur Kutlay ,&nbsp;Jalila Ben Khelil ,&nbsp;Abdul-Azeez A. Anjorin ,&nbsp;Muhammad Suleman Rana ,&nbsp;Jabrayil Jabrayilov ,&nbsp;Fatima Al Slail ,&nbsp;Dalal Al Kathiry ,&nbsp;Hasina Al Harthi ,&nbsp;Ramy Mohamed Ghazy ,&nbsp;Milad Gahwagi ,&nbsp;Alireza Mafi ,&nbsp;Parvaiz Koul ,&nbsp;Salah Al Awaidy","doi":"10.1016/j.ijregi.2025.100572","DOIUrl":"10.1016/j.ijregi.2025.100572","url":null,"abstract":"<div><h3>Objectives</h3><div>Annual vaccination is the most effective way to prevent and control the health and economic burden of seasonal influenza. Healthcare providers (HCPs) play a crucial role in vaccine acceptance and patient advocacy. This study aimed to explore the barriers and drivers of HCPs’ vaccine acceptance and advocacy for the vaccination of their patients in countries in the Middle East, Eurasia, and Africa.</div></div><div><h3>Methods</h3><div>Healthcare providers from 10 countries (Azerbaijan, Egypt, Libya, Morocco, Nigeria, Pakistan, Russia, Saudi Arabia, Tunisia, and Türkiye) were surveyed using opportunity sampling between 20^th December 2022, and 1^st March 2023. The previously developed motors of influenza vaccination acceptance (MoVac-Flu) and engagement with vaccination advocacy (MovAd) scales were used.</div></div><div><h3>Results</h3><div>In the final sample of 721 responses, Russia was the leading country, enrolling 37% of all respondents. Sentiment cluster profiles were labeled as “engaged” or “hesitant” and “confident” or “diffident.” Overall, 28% demonstrated hesitancy and 30.5% demonstrated diffident sentiments toward self-vaccination behavior. HCPs exhibited very low rates of routine vaccination and infrequent advocacy of seasonal influenza vaccinations. In contrast, those who felt engaged with influenza vaccination were more likely to be vaccinated themselves and found it easier to incorporate influenza vaccination in their practice. Those who felt engaged in influenza vaccination also felt more confident in advocating for it than those who felt hesitant. The evidence suggests that the strength of the relationship between engagement and confidence varies across countries.</div></div><div><h3>Conclusions</h3><div>This study provides insights into the behavioral patterns of HCPs regarding their own influenza vaccination and advocacy for patient vaccination. Cluster membership was a strong predictor of vaccination behaviors and attitudes, although regional differences were observed. For hesitant and diffident HCPs, tailored strategies to increase awareness and empower them regarding vaccines and vaccine-preventable diseases are crucial.</div></div>","PeriodicalId":73335,"journal":{"name":"IJID regions","volume":"14 ","pages":"Article 100572"},"PeriodicalIF":1.5,"publicationDate":"2025-01-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143394825","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Epidemiological features of scrub typhus and molecular characteristics of Orientia tsutsugamushi in north-central Bangladesh","authors":"Sultana Shabnam Nila ,&nbsp;Meiji Soe Aung ,&nbsp;Nazia Haque ,&nbsp;Shyamal Kumar Paul ,&nbsp;Syeda Anjuman Nasreen ,&nbsp;Sangjukta Roy ,&nbsp;Salma Ahmed ,&nbsp;Jobyda Khanam ,&nbsp;Mohammad Abdul Awal Bin Sayeed ,&nbsp;Shashwata Paul ,&nbsp;Noriko Urushibara ,&nbsp;Mitsuyo Kawaguchiya ,&nbsp;Nobuhide Ohashi ,&nbsp;Nobumichi Kobayashi","doi":"10.1016/j.ijregi.2025.100571","DOIUrl":"10.1016/j.ijregi.2025.100571","url":null,"abstract":"<div><h3>Objectives</h3><div>Scrub typhus is an acute febrile disease caused by <em>Orientia tsutsugamushi</em> transmitted through trombiculid mites. This study aimed to clarify the prevalence and clinical features of scrub typhus and the molecular epidemiological characteristics of <em>O. tsutsugamushi</em> in north-central Bangladesh.</div></div><div><h3>Methods</h3><div>Blood samples were collected from patients with febrile illness at a single medical institution over a 1-year period. Using DNA samples extracted from blood, <em>O. tsutsugamushi</em> was identified by nested polymerase chain reaction targeting the outer membrane protein (47-kDa) gene. Phylogenetic analysis was performed based on the genes encoding a 56-kDa type-specific antigen (TSA) and <em>trxA</em>, along with genotyping by multilocus sequence typing (MLST).</div></div><div><h3>Results</h3><div>Among the 744 patients, 72 (9.7%) were diagnosed with the scrub typhus and exhibited nausea (93%) and myalgia (75%) more commonly than did non-scrub typhus cases. On the basis of the TSA gene, eight samples were assigned to Karp-related (n = 7; clades 2 and 4b) and Gilliam (n = 1) genotypes. Among the 10 samples, nine sequence types (STs), including eight new types (ST101-ST108) were identified, with three STs grouped into clonal complex 105 (CC105). On the basis of the phylogenetic analysis of <em>trxA</em>, the Bangladeshi samples were differentiated into two clusters.</div></div><div><h3>Conclusions</h3><div>The genetic characteristics of <em>O. tsutsugamushi</em> in Bangladesh revealed a potentially dominant genetic group (Karp-c2 and CC105).</div></div>","PeriodicalId":73335,"journal":{"name":"IJID regions","volume":"14 ","pages":"Article 100571"},"PeriodicalIF":1.5,"publicationDate":"2025-01-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143313002","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A survey on the prevalence of health care–associated infections at the Fann University Hospital in Dakar, Senegal","authors":"Daye Ka ,&nbsp;Emery Yongola Osongo ,&nbsp;Fatoumata Diallo ,&nbsp;Ahmadou Lo ,&nbsp;Bruce Shinga Wembulua ,&nbsp;Catherine Sarr ,&nbsp;Maimouna Sarr ,&nbsp;Mame Diarra Mbaye ,&nbsp;Pape Amath Diagne ,&nbsp;Mamadou Baila Diallo ,&nbsp;Abdou Aziz Fall ,&nbsp;Ndéye Maguette Fall ,&nbsp;EL Hadj Cheikh Ndiaye Sy ,&nbsp;Moussa Seydi","doi":"10.1016/j.ijregi.2025.100569","DOIUrl":"10.1016/j.ijregi.2025.100569","url":null,"abstract":"<div><h3>Objectives</h3><div>This study aimed to determine the prevalence of health care–associated infections (HAIs) at Fann Hospital, describe the profile of patients with HAI, and identify the causative pathogens.</div></div><div><h3>Methods</h3><div>This was a cross-sectional survey of the records of patients hospitalized in eight departments of the Fann University Hospital for a microbiologically confirmed HAI from January 1, 2024 to March 31, 2024. Data were collected using an HAI surveillance form and analyzed using R software version 4.4.0.</div></div><div><h3>Results</h3><div>Over a 3-month period, 62 cases of HAI were recorded out of a total of 1725 patients, giving a hospital attack rate of 3.5%. The median age of the patients was 59 years (interquartile range: 68-47). Males predominated (54.8%). Hospitalized patients came directly from their homes (40.3%) or from other university hospitals (35.5%). Arterial hypertension (29%) and diabetes mellitus (19.3%) were the main comorbidities. A history of previous surgery was found in 8% of the cases. Fever was the most common clinical manifestation (71%), followed by respiratory symptoms (29%). The medical devices used were venous (100%) and urinary catheters (54.5%). The most frequently isolated bacteria were <em>Pseudomonas spp</em> (23.6%), <em>Staphylococcus aureus</em> (21.8%), and <em>Escherichia coli</em> (21.8%). In terms of the resistance phenotype, 43.6% and 21.8% of patients had extended-spectrum β-lactamase–producing Enterobacteriaceae and methicillin-resistant <em>S. aureus</em>, respectively. During hospitalization, 45 patients received nonspecific antibiotic therapy at the time of HAI. Death occurred in 11 patients, representing a fatality rate of 17.7%.</div></div><div><h3>Conclusions</h3><div>The quarterly prevalence of HAIs was high in our hospital. Therefore, it is necessary to investigate the factors associated with their occurrence.</div></div>","PeriodicalId":73335,"journal":{"name":"IJID regions","volume":"14 ","pages":"Article 100569"},"PeriodicalIF":1.5,"publicationDate":"2025-01-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143312999","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}