IJID regions最新文献

{"title":"Sociodemographic factors associated with Kyasanur forest disease in India - a retrospective study","authors":"Sulagna Chakraborty ,&nbsp;William Sander ,&nbsp;Brian F. Allan ,&nbsp;Flavia Cristina Drumond Andrade","doi":"10.1016/j.ijregi.2024.02.002","DOIUrl":"https://doi.org/10.1016/j.ijregi.2024.02.002","url":null,"abstract":"<div><h3>Objectives</h3><p>Kyasanur forest disease (KFD) is a tick-borne disease in India affecting humans and two local non-human primate species. A critical knowledge gap in the scientific literature is the lack of information on how people's sociodemographic factors influence KFD occurrence.</p></div><div><h3>Methods</h3><p>We analyzed available data on KFD from three data sources: (a) 104 peer-reviewed articles using keyword searches on PubMed Central and Google Scholar, (b) 116 Program for Monitoring Emerging Diseases reports, and (c) an acute febrile illness surveillance data set on KFD from a report by the government of India. We performed statistical analyses to calculate the prevalence of KFD by state and differences in KFD cases by sex and age group.</p></div><div><h3>Results</h3><p>All three data sets used indicate that KFD cases and deaths have occurred predominantly in the 15-64 years age group (literature: 87% cases and 95% deaths, Program for Monitoring Emerging Diseases: 78% cases and 78% deaths, acute febrile illness: 96% cases [no breakdown for acute febrile illness death data]). Data reporting varies across states and is non-standardized.</p></div><div><h3>Conclusions</h3><p>The inconsistent reporting of sociodemographic data on KFD in India has created a gap in our understanding of its impact on different social groups. Collecting and reporting data on sociodemographic factors is critical to understanding the epidemiology of KFD and designing effective public health interventions.</p></div>","PeriodicalId":73335,"journal":{"name":"IJID regions","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-02-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2772707624000122/pdfft?md5=2c32cd888d1c66c39ca718acf3d69994&pid=1-s2.0-S2772707624000122-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139986562","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Community engagement and antimalarial drugs medication as the first line of defense in the fight against antimalarial drug resistance in some endemic localities in Cameroon","authors":"David Denis Sofeu-Feugaing ,&nbsp;Fabrice Nkengeh Ajonglefac ,&nbsp;Marcel Nyuylam Moyeh ,&nbsp;Marianne Elodie Essende ,&nbsp;Vanessa Tita Jugha ,&nbsp;Germain Sotoing Taiwe","doi":"10.1016/j.ijregi.2024.02.001","DOIUrl":"10.1016/j.ijregi.2024.02.001","url":null,"abstract":"<div><h3>Objectives</h3><p>Malaria burden is primarily owing to resistance of parasites and vectors to frontline drugs and insecticides, respectively. Increasing awareness of factors contributing to parasite resistance to antimalarials within communities is crucial. This study assessed how community knowledge, attitudes, and practices (KAPs) influence factors contributing to antimalarial resistance across four malaria ecological zones in Cameroon.</p></div><div><h3>Methods</h3><p>To accomplish this, structured questionnaires were administered to 980 volunteers from four geographical locations in English or French (the official languages of Cameroon). The data were organized and tested for normality. Spearman rank correlation was used to examine the connection between KAP and malaria.</p></div><div><h3>Results</h3><p>The mean KAP scores were 5.69 ± 1.47, 5.91 ± 1.25, and 5.66 ± 1.84, respectively, on a nine-point scale. Antimalarials commonly used were artemisinin-based combination therapies (37.96%), chloroquine (4.29%), quinine (22.24%), paracetamol (12.96%), and native drugs (19.80%). Up to 49.49% of the participants practiced self-medication, whereas 76.43% bought medications from licensed pharmacies, 10.61% bought from roadside vendors, and 23.57% relied on traditional/herbal medicines. We observed significant and medium positive linear correlations at <em>P</em> &lt;0.01 between knowledge-attitude (r = 0.528), knowledge-practice (r = 0.400), and attitude-practice (r = 0.496).</p></div><div><h3>Conclusions</h3><p>Despite the general fair level of awareness of proper management and use of antimalarial drugs in the communities, the high level of self-medication and gross neglect of certain risk factors that may promote the emergence and spread of drug-resistant parasites is concerning.</p></div>","PeriodicalId":73335,"journal":{"name":"IJID regions","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-02-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2772707624000110/pdfft?md5=72998841afd0aab602d2a8c5c73ff64d&pid=1-s2.0-S2772707624000110-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139819613","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Validating a questionnaire to identify women in the first trimester of pregnancy during preventive chemotherapy interventions against soil-transmitted helminths in northwestern Tanzania","authors":"Humphrey D. Mazigo ,&nbsp;Antonio Montresor","doi":"10.1016/j.ijregi.2024.01.010","DOIUrl":"https://doi.org/10.1016/j.ijregi.2024.01.010","url":null,"abstract":"<div><h3>Objectives</h3><p>To evaluate the performance of a questionnaire in assessing the pregnancy status of women of reproductive age during preventive chemotherapy interventions.</p></div><div><h3>Methods</h3><p>A questionnaire (20 questions) was administered to 1217 women of reproductive age (≥18 years) from Ilemela and Buchosa districts, northwestern Tanzania. A single urine sample was collected from each of them and tested using a rapid pregnancy test for presence of pregnant.</p></div><div><h3>Results</h3><p>Overall, 10.8% (132/1217) of the women reported to be pregnant at the specific question in the questionnaire. The rapid pregnancy test identified 15.1% (184/1217) of the women to be pregnant. In total, 86.4% (114/132) of the women who reported to be pregnant during the interview were confirmed to be pregnant using the rapid pregnant test. The question on pregnancy demonstrated an overall sensitivity of 62% and specificity of 98.3%.</p></div><div><h3>Conclusions</h3><p>The questionnaire performance was not completely satisfactory; however, it managed to identify pregnant women in the first trimester. The question on the last date of the start of the menstrual period yield the highest sensitivity and appeared to be the key one used in combination with other questions. Further validation of these results in other countries with different cultures are recommended to fully evaluate the performance of this method.</p></div>","PeriodicalId":73335,"journal":{"name":"IJID regions","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-02-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2772707624000109/pdfft?md5=6c0f3dc8af5597a4ff51a88b5e8f20e4&pid=1-s2.0-S2772707624000109-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139942998","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Descriptive Analysis of Measles Outbreak in Liberia, 2022","authors":"Bode Shobayo ,&nbsp;Chukwuma David Umeokonkwo ,&nbsp;Ralph Weah Jetoh ,&nbsp;Julius S.M. Gilayeneh Sr ,&nbsp;Godwin Akpan ,&nbsp;Maame Amo-Addae ,&nbsp;Jane Macauley ,&nbsp;Rachel T. Idowu","doi":"10.1016/j.ijregi.2024.01.008","DOIUrl":"10.1016/j.ijregi.2024.01.008","url":null,"abstract":"<div><h3>Background</h3><p>Liberia reported a large outbreak of measles involving all the counties in 2022. We conducted a descriptive analysis of the measles surveillance data to understand the trend of the outbreak and guide further policy action to prevent future outbreaks.</p></div><div><h3>Methods</h3><p>We analyzed the measles surveillance data from Epi week 1 to 51, 2022. All the laboratory-confirmed cases, clinically compatible and epidemiologically linked cases were included in the analysis, the variables of interest included the patient's age, sex, place of residence, measles classification, measles vaccination status, and outcome. We cleaned and analyzed the data using R version 4.2.0 and Arc GIS Pro. The demographic characteristics of the cases were presented, the progression of the cases was presented in Epicurve and the spatial distribution and the case fatality rate (CFR) of the case were presented at the district level using the Arc GIS Pro.</p></div><div><h3>Results</h3><p>The median age of the cases was 4 years (interquartile range: 2-8 years). Children under five years of age constituted 60% of the cases (4836/8127), and females accounted for 52% (4204/8127) of the cases. Only 1% (84/8127) of the cases had documentary evidence of receiving at least one dose of measles-containing vaccine (MCV). Only 3 out of 92 health districts in the country did not report a case of measles during the period under review. The overall cases fatality rate was 1% however CFR of up to 10% were reported in some districts.</p></div><div><h3>Conclusion</h3><p>The outbreak of measles involved almost all the districts of the country, exposing a possible nationwide suboptimal immunization coverage for MCV. The high CFR reported in some districts needs further investigation.</p></div>","PeriodicalId":73335,"journal":{"name":"IJID regions","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-01-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2772707624000092/pdfft?md5=bb06fbb9c347076519925a55ed16379e&pid=1-s2.0-S2772707624000092-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139640286","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Recent cluster of neonatal enteroviral myocarditis cases in the United Kingdom of Great Britain and Northern Ireland - current scenario and counteracting prospects","authors":"Amrita Pattanaik,&nbsp;Sushma Bhandarkar B,&nbsp;Sreelakshmi V,&nbsp;Chiranjay Mukhopadhyay","doi":"10.1016/j.ijregi.2024.01.009","DOIUrl":"10.1016/j.ijregi.2024.01.009","url":null,"abstract":"<div><h3>Objectives</h3><p>Neonatal myocarditis is a rare but life-threatening complication of enterovirus infection that presents like bacterial sepsis.</p></div><div><h3>Outbreak</h3><p>A sudden upsurge in cases of neonatal enteroviral myocarditis, reported from South West England and South Wales between June 2022 and April 2023 has alerted health agencies to bring in counteracting measures.</p></div><div><h3>Impact</h3><p>In view of this outbreak situation, the World Health Organisation advisory has urged clinicians seeing neonates and infants with shock may consider myocarditis as a differential diagnosis and test for enteroviruses.</p></div>","PeriodicalId":73335,"journal":{"name":"IJID regions","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-01-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2772707624000080/pdfft?md5=cd343a2efafe2403c0582d0e80552c4c&pid=1-s2.0-S2772707624000080-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139632170","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Pre-vaccination seroprevalence of SARS-CoV-2 antibodies in the Volta Region, Ghana","authors":"Enoch Aninagyei ,&nbsp;Reuben Ayivor-Djanie ,&nbsp;Jones Gyamfi ,&nbsp;Marfo Edward Aboagye ,&nbsp;Grace Semabia Kpeli ,&nbsp;William Kwabena Ampofo ,&nbsp;John Owusu Gyapong ,&nbsp;Kwabena Obeng Duedu","doi":"10.1016/j.ijregi.2024.01.007","DOIUrl":"10.1016/j.ijregi.2024.01.007","url":null,"abstract":"<div><h3>Objectives</h3><p>Before administration of the first dose of the AstraZeneca 2019 SARS-CoV-2 vaccine to selected prioritized groups in the Volta regional capital of Ghana, we determined the pre-vaccination status of prospective recipients and established the baseline exposure status 1 year after the first case was reported.</p></div><div><h3>Methods</h3><p>After informed consent, blood samples were collected for the detection of SARS-CoV-2 immunoglobulin (Ig) M/IgG antibodies using rapid diagnostic test kits. A total of 409 individuals (mean age 27 years) consented and participated in the study, comprising 70% students and others were health staff and educators who presented themselves for vaccination.</p></div><div><h3>Results</h3><p>The overall exposure rate of SARS-CoV-2 was 12.7% (95% confidence interval [CI] 9.6-16.3). The prevalence of SARS-CoV-2 IgM and IgG were 4.2% (95% CI 2.4-6.6) and 5.6% (95% CI 3.6-8.3), respectively. IgM and IgG were detected in 2.9% (95% CI 1.5-5.1) of the respondents. The exposure rates were higher in participants over 40 years old (15.5%). Participants without a history of COVID-19–like symptoms had an exposure rate of 13.0% and those without any chronic diseases was 13.2%.</p></div><div><h3>Conclusion</h3><p>Pre-vaccination exposure was relatively low and underscored the need for vaccination i to increase protection in communities and disease outcomes.</p></div>","PeriodicalId":73335,"journal":{"name":"IJID regions","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-01-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2772707624000079/pdfft?md5=2d01d4bb57b1dd28d6d6c3f9359df221&pid=1-s2.0-S2772707624000079-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139637193","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Corrigendum to “Second round statewide sentinel-based population survey for estimation of the burden of active infection and anti-SARS-CoV-2 IgG antibodies in the general population of Karnataka, India, during January-February 2021” [IJID Regions Vol 1(2021) pages 107–116]","authors":"M. Rajagopal Padma ,&nbsp;Prameela Dinesh ,&nbsp;Rajesh Sundaresan ,&nbsp;Siva Athreya ,&nbsp;Shilpa Shiju ,&nbsp;Parimala S. Maroor ,&nbsp;R. Lalitha Hande ,&nbsp;Jawaid Akhtar ,&nbsp;Trilok Chandra ,&nbsp;Deepa Ravi ,&nbsp;Eunice Lobo ,&nbsp;Yamuna Ana ,&nbsp;Prafulla Shriyan ,&nbsp;Anita Desai ,&nbsp;Ambica Rangaiah ,&nbsp;Ashok Munivenkatappa ,&nbsp;S. Krishna ,&nbsp;Shantala Gowdara Basawarajappa ,&nbsp;H.G. Sreedhara ,&nbsp;K.C. Siddesh ,&nbsp;Giridhara Rathnaiah Babu","doi":"10.1016/j.ijregi.2024.01.001","DOIUrl":"https://doi.org/10.1016/j.ijregi.2024.01.001","url":null,"abstract":"","PeriodicalId":73335,"journal":{"name":"IJID regions","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-01-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S277270762400002X/pdfft?md5=23bdf33bab9021ce146859cedc49e437&pid=1-s2.0-S277270762400002X-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139503457","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Lung abnormalities on computed tomography of Vietnamese patients with COVID-19 and the association with medical variables","authors":"Cong Dien Trinh ,&nbsp;Van Nam Le ,&nbsp;Van Nguyen Bang Le ,&nbsp;Ngoc Thach Pham ,&nbsp;Van Duyet Le","doi":"10.1016/j.ijregi.2024.01.006","DOIUrl":"10.1016/j.ijregi.2024.01.006","url":null,"abstract":"<div><h3>Objectives</h3><p>Patients with COVID-19 may experience a lung injury without presenting clinical symptoms. Early detection of lung injury in patients with COVID-19 is required to enhance prediction and prevent severe progression.</p></div><div><h3>Methods</h3><p>Lung lesions in patients with COVID-19 were defined using the Fleischner Society terminology. Chest computed tomography lesions and their correlation with demographic characteristics and medical variables were identified.</p></div><div><h3>Results</h3><p>Patients with mild and moderate COVID-19 had up to 45% lung injuries, whereas critical patients had 55%. However, patients with mild and moderate COVID-19 typically had low-level lung injuries. Ground-glass (68.1%), consolidation (48.8%), opacity (36.3%), and nodular (6.9%) lung lesions were the most prevalent in patients with COVID-19. Patients with COVID-19 infected with the Delta variant had worse lung injury than those infected with the Alpha and Omicron. People vaccinated with ≥2 doses showed a lower risk of lung injury than those vaccinated with &lt;1 dose. Patients &lt;18 years old were less likely to have a lung injury than patients &gt;18 years old. The treatment outcomes were unaffected by the severity of the lung injury.</p></div><div><h3>Conclusion</h3><p>Patients with mild COVID-19 had a similar risk of lung injury as patients with severe COVID-19. Thus, using chest computed tomography to detect lung injury can enhance the treatment outcomes and reduce the patient's risk of pulmonary complications.</p></div>","PeriodicalId":73335,"journal":{"name":"IJID regions","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-01-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2772707624000067/pdfft?md5=548b01d0b9aad5e459104476c4848072&pid=1-s2.0-S2772707624000067-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139637305","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Whole genome sequencing and phylogenetic analysis of SARS-CoV-2 strains isolated during the COVID-19 pandemic in Nigeria","authors":"Adedolapo B. Olorunfemi ,&nbsp;Salma A.R. Suliman ,&nbsp;Tung T. Tran ,&nbsp;Babatunde Ayorinde ,&nbsp;Muinah A. Fowora ,&nbsp;Bamidele A. Iwalokun ,&nbsp;Olugbenga A. Olowe ,&nbsp;Oluyinka O. Opaleye ,&nbsp;Mohamed Osman ,&nbsp;Babatunde L. Salako ,&nbsp;Richard Adegbola ,&nbsp;Bolaji N. Thomas ,&nbsp;Srinivas Reddy Pallerla ,&nbsp;Thirumalaisamy P. Velavan ,&nbsp;Olusola Ojurongbe","doi":"10.1016/j.ijregi.2024.01.005","DOIUrl":"10.1016/j.ijregi.2024.01.005","url":null,"abstract":"<div><h3>Objectives</h3><p>The emergence and spread of SARS-CoV-2 have stimulated ongoing research into the virus transmission dynamics, circulating variants, and potential mutations. This study was conducted to understand the genomic dynamics of the epidemic in Nigeria.</p></div><div><h3>Design</h3><p>Whole genome sequencing was conducted on SARS-CoV-2 samples collected during the first and second outbreaks using the Oxford Nanopore MinION sequencing platform. Phylogenetic analysis was conducted, and genomes were grouped into different pangolin lineages.</p></div><div><h3>Results</h3><p>The study revealed four circulating SARS-CoV-2 variants. The Alpha (B.1.1.7) variant was the most prevalent (32.7%), followed by Beta (B.1 B.1.1, L.3, and B.1.1.318) (30.8%), Eta (B.1.525) (28.9%), and Delta (B.1.617, AY.1, AY.109, and AY.36) (7.7%). Phylogenetic analysis revealed three clusters with four Nextstrain clades (20I, 20B, 21D, and 21J). The Alpha lineages (B.1.1.7) clustered with references from Italy. The Beta lineages (Clade 20B) (B.11, B.11318, and L3) and sub-lineage B.11 were distinct. Sub-lineage B.11318 is clustered with references from the USA, whereas sub-lineage L3 is clustered with references from Russia, the Philippines, Australia, and Japan. The 21D and 21J, belonging to two Pango lineages, Eta (B.1525) and Delta (B.1.617 and AY.109), showed high genetic similarity.</p></div><div><h3>Conclusion</h3><p>The phylogenetic relatedness of the lineages suggests multiple virus introduction, which could be a source of more virulent, locally adapted variants.</p></div>","PeriodicalId":73335,"journal":{"name":"IJID regions","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-01-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2772707624000043/pdfft?md5=cabf72dc04a7a30fe84f110e841c1a44&pid=1-s2.0-S2772707624000043-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139538837","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Prevalence of respiratory syncytial virus infection and associated factors in children aged under five years with severe acute respiratory illness and influenza-like illness in Ethiopia","authors":"Adamu Tayachew ,&nbsp;Gizaw Teka ,&nbsp;Ayele Gebeyehu ,&nbsp;Wolde Shure ,&nbsp;Mengistu Biru ,&nbsp;Leuleseged Chekol ,&nbsp;Tsegaye Berkessa ,&nbsp;Eyasu Tigabu ,&nbsp;Lehageru Gizachew ,&nbsp;Admikew Agune ,&nbsp;Melaku Gonta ,&nbsp;Aster Hailemariam ,&nbsp;Ergetu Gedefaw ,&nbsp;Adane Woldeab ,&nbsp;Ayinalem Alemu ,&nbsp;Yimam Getaneh ,&nbsp;Leuel Lisanwork ,&nbsp;Kalkidan Yibeltal ,&nbsp;Ebba Abate ,&nbsp;Aschalew Abayneh ,&nbsp;Firehiwot Workineh","doi":"10.1016/j.ijregi.2024.01.004","DOIUrl":"10.1016/j.ijregi.2024.01.004","url":null,"abstract":"<div><h3>Objectives</h3><p>Acute respiratory infections because of respiratory syncytial viruses (RSVs) are among the major leading causes of morbidity and mortality in children worldwide. RSV prevalence and its contributing factors among children aged under 5 years in Ethiopia are not well studied. To assess the prevalence and associated factors of RSV infection in children aged under 5 years using influenza sentinel surveillance sites in Ethiopia.</p></div><div><h3>Methods</h3><p>A cross-sectional study design was used utilizing influenza-like illness/sever acute respiratory illness surveillance data from January 2021 to December 2022 at the Ethiopian Public Health Institute.</p></div><div><h3>Results</h3><p>In total, 2234 cases were included, with an overall RSV positivity rate of 16.2%. The RSV positivity rate was high in children aged under 1 year (22.8%) and during fall season (24.8%). The RSV positivity rate was significantly associated with ages under 1 year (adjusted odds ratio [AOR] 2.8, 95% confidence interval [CI]: 1.89-4.15) and 1-2 years (AOR 1.9, 95% CI: 1.26-2.73) and the fall season (AOR 1.67, 95% CI: 1.17-2.38).</p></div><div><h3>Conclusion</h3><p>The study revealed that a considerably high RSV positivity rate was detected in children aged under 5 years. The age of children and season have a significant association with RSV positivity rate. Further studies of RSV viral genotype, clinical characteristics, and disease outcome need to be conducted for a better understanding of the virus and disease outcome.</p></div>","PeriodicalId":73335,"journal":{"name":"IJID regions","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-01-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2772707624000055/pdfft?md5=94f65cb75414f5bc26fffe6eaac78c68&pid=1-s2.0-S2772707624000055-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139634954","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}