IEEE Biomedical Circuits and Systems Conference : healthcare technology : [proceedings]. IEEE Biomedical Circuits and Systems Conference最新文献_第3页

Electronics for a Safe Direct Current Stimulator. 安全直流刺激器用电子器件。

IEEE Biomedical Circuits and Systems Conference : healthcare technology : [proceedings]. IEEE Biomedical Circuits and Systems Conference Pub Date : 2017-10-01 Epub Date: 2018-03-29 DOI: 10.1109/BIOCAS.2017.8325191

Patrick Ou, Gene Fridman

{"title":"Electronics for a Safe Direct Current Stimulator.","authors":"Patrick Ou, Gene Fridman","doi":"10.1109/BIOCAS.2017.8325191","DOIUrl":"https://doi.org/10.1109/BIOCAS.2017.8325191","url":null,"abstract":"Commercially available neuroprostheses, while successful and effective, are limited in their functionality by their reliance on pulsatile stimulation. Direct current (DC) has been shown to have great potential for the purposes of neuromodulation; however, direct current cannot be applied directly to neurons due to the charge injection thresholds of electrodes. We are developing a Safe Direct Current Stimulator (SDCS) that applies ionic direct current (iDC) without inducing toxic electrochemical reactions. The current design of the SDCS uses a series of eight valves in conjunction with four electrodes to rectify ionic current in microfluidic channels. This paper outlines the design, implementation, and testing of the electronics of the SDCS. These electronics will ultimately be interfaced with a separate microfluidic circuit in the device prototype. Testing the outputs of the electronics confirmed adherence to its design requirements. The completion of the SDCS electronics enables the further development of iDC as a mechanism for neuromodulation.","PeriodicalId":73279,"journal":{"name":"IEEE Biomedical Circuits and Systems Conference : healthcare technology : [proceedings]. IEEE Biomedical Circuits and Systems Conference","volume":"2017 ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2017-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1109/BIOCAS.2017.8325191","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"36657946","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 5

2048 Action Potential Recording Channels with 2.4 µVrms Noise and Stimulation Artifact Suppression. 2048 个动作电位记录通道，具有 2.4 µVrms 噪声和刺激伪影抑制功能。

IEEE Biomedical Circuits and Systems Conference : healthcare technology : [proceedings]. IEEE Biomedical Circuits and Systems Conference Pub Date : 2017-01-26 DOI: 10.1109/BioCAS.2016.7833750

Vijay Viswam, Yihui Chen, Amir Shadmani, Jelena Dragas, Raziyeh Bounik, Radivojevic Milos, Jan Müller, Andreas Hierlemann

引用次数: 0

Automatic Drift Cancellation of Implanted Bladder Pressure Sensor. 植入式膀胱压力传感器的自动漂移消除。

IEEE Biomedical Circuits and Systems Conference : healthcare technology : [proceedings]. IEEE Biomedical Circuits and Systems Conference Pub Date : 2015-10-22 DOI: 10.1109/BioCAS.2015.7348430

Steve Majerus, Margot S Damaser

{"title":"Automatic Drift Cancellation of Implanted Bladder Pressure Sensor.","authors":"Steve Majerus, Margot S Damaser","doi":"10.1109/BioCAS.2015.7348430","DOIUrl":"https://doi.org/10.1109/BioCAS.2015.7348430","url":null,"abstract":"Implanted pressure sensors suffer from long-term offset drift due to atmospheric changes, package moisture absorption, and patient factors such as posture, implant shift, and tissue overgrowth. Traditionally, wide dynamic range instrumentation is used to satisfy the full-scale and sensitivity requirements for a given application. Transmission of extra bits greatly increases the power draw of an implanted medical device, and simple AC-coupling cannot monitor static pressures. We present a mixed-signal offset cancellation loop to maximize the AC dynamic range of instrumentation circuitry. A digital implementation allows for designer control of the cancellation system time constant and was specifically designed for power-gated pressure sensors. Pressure offset is calculated by digital integration and a bipolar IDAC with coarse/fine tuning injects an offset-cancelling current into a standard piezoresistive MEMS pressure sensor. Test results showed a dynamic range increase of 2.9 bits using dynamic offset cancellation, for an effective sensing range of 11 bits using 8-bit instrumentation. The measured step response of the system showed an overall highpass response of 2.3 - 3.8 mHz. This approach is therefore relevant for bio-sensing of pressures in organs with a very slow physiologic response, e.g. the bladder.","PeriodicalId":73279,"journal":{"name":"IEEE Biomedical Circuits and Systems Conference : healthcare technology : [proceedings]. IEEE Biomedical Circuits and Systems Conference","volume":"2015 ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2015-10-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1109/BioCAS.2015.7348430","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"38908520","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

Wireless Implantable Pressure Monitor for Conditional Bladder Neuromodulation. 无线植入式压力监测器用于条件膀胱神经调节。

IEEE Biomedical Circuits and Systems Conference : healthcare technology : [proceedings]. IEEE Biomedical Circuits and Systems Conference Pub Date : 2015-10-01 Epub Date: 2015-12-07 DOI: 10.1109/biocas.2015.7348337

Steve Majerus, Iryna Makovey, Hui Zhui, Wen Ko, Margot S Damaser

{"title":"Wireless Implantable Pressure Monitor for Conditional Bladder Neuromodulation.","authors":"Steve Majerus, Iryna Makovey, Hui Zhui, Wen Ko, Margot S Damaser","doi":"10.1109/biocas.2015.7348337","DOIUrl":"https://doi.org/10.1109/biocas.2015.7348337","url":null,"abstract":"Conditional neuromodulation in which neurostimulation is applied or modified based on feedback is a viable approach for enhanced bladder functional stimulation. Current methods for measuring bladder pressure rely exclusively on external catheters placed in the bladder lumen. This approach has limited utility in ambulatory use as required for chronic neuromodulation therapy. We have developed a wireless bladder pressure monitor to provide real-time, catheter-free measurements of bladder pressure to support conditional neuromodulation. The device is sized for submucosal cystoscopic implantation into the bladder. The implantable microsystem consists of an ultra-low-power application specific integrated circuit (ASIC), micro-electro-mechanical (MEMS) pressure sensor, RF antennas, and a miniature rechargeable battery. A strategic approach to power management miniaturizes the implant by reducing the battery capacity requirement. Here we describe two approaches to reduce the average microsystem current draw: switched-bias power control and adaptive rate transmission. Measurements on human cystometric tracings show that adaptive transmission rate can save an average of 96% power compared to full-rate transmission, while adding 1.6% RMS error. We have chronically implanted the wireless pressure monitor for up to 4 weeks in large animals. To the best of our knowledge these findings represent the first examples of catheter-free, real-time bladder pressure sensing from a pressure monitor chronically implanted within the bladder detrusor.","PeriodicalId":73279,"journal":{"name":"IEEE Biomedical Circuits and Systems Conference : healthcare technology : [proceedings]. IEEE Biomedical Circuits and Systems Conference","volume":"2015 ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2015-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1109/biocas.2015.7348337","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39178012","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 17

On Using Residual Voltage to Estimate Electrode Model Parameters for Damage Detection. 残差电压估计电极模型参数在损伤检测中的应用。

IEEE Biomedical Circuits and Systems Conference : healthcare technology : [proceedings]. IEEE Biomedical Circuits and Systems Conference Pub Date : 2015-10-01 DOI: 10.1109/BioCAS.2015.7348354

Ashwati Krishnan, Shawn K Kelly

引用次数: 2

Design of a low-power adaptive LMS equalizer for hearing-aid applications 助听器低功耗自适应LMS均衡器的设计

IEEE Biomedical Circuits and Systems Conference : healthcare technology : [proceedings]. IEEE Biomedical Circuits and Systems Conference Pub Date : 2014-12-11 DOI: 10.1109/BioCAS.2014.6981810

J. P. Cerqueira, S. Haddad

引用次数: 2

Redundant safety features in a high-channel-count retinal neurostimulator. 高通道计数视网膜神经刺激器的冗余安全功能。

IEEE Biomedical Circuits and Systems Conference : healthcare technology : [proceedings]. IEEE Biomedical Circuits and Systems Conference Pub Date : 2014-10-01 DOI: 10.1109/BioCAS.2014.6981701

Shawn K Kelly, William F Ellersick, Ashwati Krishnan, Patrick Doyle, Douglas B Shire, John L Wyatt, Joseph F Rizzo

{"title":"Redundant safety features in a high-channel-count retinal neurostimulator.","authors":"Shawn K Kelly, William F Ellersick, Ashwati Krishnan, Patrick Doyle, Douglas B Shire, John L Wyatt, Joseph F Rizzo","doi":"10.1109/BioCAS.2014.6981701","DOIUrl":"https://doi.org/10.1109/BioCAS.2014.6981701","url":null,"abstract":"Safety features embedded in a 256-channel retinal prosthesis integrated circuit are presented. The biology of the retina and the electrochemistry of the electrode-tissue interface demand careful planning and design of the safety features of an implantable retinal stimulation device. We describe the internal limits and communication safety features of our ASIC, but we focus on monitoring and protection circuits for the electrode-tissue interface. Two independent voltage monitoring circuits for each channel measure the electrode polarization voltage at two different times in the biphasic stimulation cycle. The monitors ensure that the charged electrode stays within the electrochemical water window potentials, and that the discharged electrode is within a small window near the counter electrode potential. A switch to connect each electrode to the counter electrode between pulses protects against a wide range of device failures. Additionally, we describe work on an active feedback system to ensure that the electrode voltage is at zero.","PeriodicalId":73279,"journal":{"name":"IEEE Biomedical Circuits and Systems Conference : healthcare technology : [proceedings]. IEEE Biomedical Circuits and Systems Conference","volume":"2014 ","pages":"216-219"},"PeriodicalIF":0.0,"publicationDate":"2014-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1109/BioCAS.2014.6981701","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"34430730","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 6

A Low-Cost Smartphone-Based Electrochemical Biosensor for Point-of-Care Diagnostics. 一种低成本的基于智能手机的电化学生物传感器，用于即时诊断。

IEEE Biomedical Circuits and Systems Conference : healthcare technology : [proceedings]. IEEE Biomedical Circuits and Systems Conference Pub Date : 2014-10-01 DOI: 10.1109/BioCAS.2014.6981725

Alexander Sun, Travis Wambach, A G Venkatesh, Drew A Hall

{"title":"A Low-Cost Smartphone-Based Electrochemical Biosensor for Point-of-Care Diagnostics.","authors":"Alexander Sun, Travis Wambach, A G Venkatesh, Drew A Hall","doi":"10.1109/BioCAS.2014.6981725","DOIUrl":"https://doi.org/10.1109/BioCAS.2014.6981725","url":null,"abstract":"This paper describes the development of a smartphone-based electrochemical biosensor module. The module contains a low power potentiostat that interfaces and harvests power from a smartphone through the phone's audio jack. A prototype with two different potentiostat designs was constructed and used to conduct proof of concept cyclic voltammetry experiments with potassium ferro-/ferricyanide (K4[Fe(CN)6] / K3[Fe(CN)6]) in a side-by-side comparison with a laboratory grade instrument. Results show that the module functions within the available power budget and that the recovered voltammogram data matches well with the data from an expensive bench top tool. Excluding the loses from supply rectification and regulation, the module consumes either 5.7 mW or 4.3 mW peak power, depending on which of the two discussed potentiostat designs is used. At single quantity pricing, the hardware for the prototype device costs less than $30.","PeriodicalId":73279,"journal":{"name":"IEEE Biomedical Circuits and Systems Conference : healthcare technology : [proceedings]. IEEE Biomedical Circuits and Systems Conference","volume":"2014 ","pages":"312-315"},"PeriodicalIF":0.0,"publicationDate":"2014-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1109/BioCAS.2014.6981725","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"33288948","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 63

Wheeze detection using fractional Hilbert transform in the time domain 基于分数阶希尔伯特变换的时域喘息检测

IEEE Biomedical Circuits and Systems Conference : healthcare technology : [proceedings]. IEEE Biomedical Circuits and Systems Conference Pub Date : 2012-01-01 DOI: 10.1109/BioCAS.2012.6418433

Zhenzhen Li, Xiaoming Wu

引用次数: 0

Brunnstrom stage automatic evaluation for stroke patients using extreme learning machine 基于极限学习机的脑卒中患者Brunnstrom分期自动评估

IEEE Biomedical Circuits and Systems Conference : healthcare technology : [proceedings]. IEEE Biomedical Circuits and Systems Conference Pub Date : 2012-01-01 DOI: 10.1109/BioCAS.2012.6418417

Lei Yu, Ji-ping Wang, Qiang Fang, Yue Wang

引用次数: 0