Acta gastro-enterologica Belgica最新文献_第3页

Metabolic dysfunction-associated steatotic liver disease : the tree that hides the forest? 代谢功能障碍相关脂肪性肝病：隐藏在森林中的树木？

IF 1.3 4区医学

Acta gastro-enterologica Belgica Pub Date : 2024-04-01 DOI: 10.51821/87.2.13087

G Henin, P Baldin, C Frans, V Havelange, B Delire, J C Yombi, N Lanthier

引用次数: 0

Different aspects of immunological profile in patients with Non-Alcoholic Fatty liver disease. 非酒精性脂肪肝患者免疫特征的不同方面。

IF 1.3 4区医学

Acta gastro-enterologica Belgica Pub Date : 2024-04-01 DOI: 10.51821/87.2.12205

H A Osman, M Tag-Adeen, U M Abdelaal, E Elgezawy, K A Nasif, A Nafady

{"title":"Different aspects of immunological profile in patients with Non-Alcoholic Fatty liver disease.","authors":"H A Osman, M Tag-Adeen, U M Abdelaal, E Elgezawy, K A Nasif, A Nafady","doi":"10.51821/87.2.12205","DOIUrl":"https://doi.org/10.51821/87.2.12205","url":null,"abstract":"Background: NAFLD is thought to affect approximately one-fourth of the world's population. Therefore, we evaluated the role of serum complement and immunoglobulins in the NAFLD pathogenesis.Patients and methods: 200 participants were used in this study, divided into two groups; Group I: 100 NAFLD patients and Group II: 100 healthy volunteers. The diagnosis of NAFLD is based on non-invasive methods, following the EASL guideline 2022. IgG, IgM, IgA, C3, and C4 assays were performed on all participants.Results: When the immunological profiles of patients with NAFLD and healthy controls were compared, it was found that the mean IgA in NAFLD patients was (4.20±5.07), whereas the mean IgA in healthy controls was (2.22±1.05) (P=0.000). Additionally, a significant increase in IgG was found in NAFLD patients (17.08±3.87) compared with healthy controls (11.59±3.34), with a P value of (p<0.001). complement C3 and complement C4 levels significantly increased in nonalcoholic fatty liver disease patients (1.28± 0.61 and 0.40 ± 0.19, respectively), compared to healthy controls (0.90 ±0.27 and 0.30 ±0.12, respectively), with a significant P value (p<0.001 for each).Conclusions: Elevated IgA, IgG, C3 and C4 exist in patients with NAFLD and could be associated with fatty liver development and progression of hepatic fibrosis in patients with NAFLD.","PeriodicalId":7322,"journal":{"name":"Acta gastro-enterologica Belgica","volume":null,"pages":null},"PeriodicalIF":1.3,"publicationDate":"2024-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142103332","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Familial chylomicronemia syndrome: a novel mutation in the lipoprotein lipase gene. 家族性乳糜微粒血症综合征：脂蛋白脂肪酶基因的新型突变。

IF 1.3 4区医学

Acta gastro-enterologica Belgica Pub Date : 2024-04-01 DOI: 10.51821/87.2.12025

S Van Biervliet, S Vande Velde, P De Bruyne, B Callewaert, P Verloo, R De Bruyne

引用次数: 0

Bismuth-based quadruple therapy versus standard triple therapy for the eradication of Helicobacter pylori in Belgium: a multicentre, non-blinded randomized, prospective study. 比利时根除幽门螺杆菌的铋剂四联疗法与标准三联疗法：一项多中心、非盲法随机前瞻性研究。

IF 1.3 4区医学

Acta gastro-enterologica Belgica Pub Date : 2024-04-01 DOI: 10.51821/87.2.12142

S François, F Mana, R Ntounda, V Lamy, S Cadranel, P Bontems, V Miendje Deyi, E Macken, S Kindt

{"title":"Bismuth-based quadruple therapy versus standard triple therapy for the eradication of Helicobacter pylori in Belgium: a multicentre, non-blinded randomized, prospective study.","authors":"S François, F Mana, R Ntounda, V Lamy, S Cadranel, P Bontems, V Miendje Deyi, E Macken, S Kindt","doi":"10.51821/87.2.12142","DOIUrl":"10.51821/87.2.12142","url":null,"abstract":"Background: Helicobacter pylori (Hp) infection predisposes to malignant and non-malignant diseases warranting eradication. In Belgium, resistance rates for clarithromycin demonstrate regional variations making the use of standard triple therapy (STT) borderline acceptable. According to a recent Belgian survey, STT and bismuth-based quadruple therapy (BQT), are equally frequent prescribed as first line treatment for treatment naïve Hp positive patients. This study aims to evaluate the eradication rates (ER) of BQT versus STT.Methods: Multicentre, non-blinded randomized, prospective study comparing ER in treatment-naïve Hp positive patients. ER were compared by intention to treat (ITT) and per protocol (PP) analysis.Results: Overall 250 patients were included (STT 126, BQT 124). Seventeen patients were lost to follow-up (6,8%). No significant difference in ER between BQT and STT was observed in ITT (73% vs 68%, p= 0,54) neither in PP analysis (81% vs 75%, p= 0,33). Side effects and endoscopic findings were comparable between groups. Post-hoc analysis showed no differences according to gender or site allocation.Conclusion: The numerical advantage of BQT did not translate in a significant improvement of ER when compared with STT. These results question the cost-effectiveness of BQT, while confirming the suboptimal eradication rates on STT. A nationwide monitoring of resistance patterns, maximal investments in treatment adherence as well as a detailed follow-up of the changing treatment landscape are mandatory to continuously optimise Hp ER in Belgium.","PeriodicalId":7322,"journal":{"name":"Acta gastro-enterologica Belgica","volume":null,"pages":null},"PeriodicalIF":1.3,"publicationDate":"2024-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142103328","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Acute grade IV toxic hepatitis due to the e-cigarette. 电子烟导致急性 IV 级中毒性肝炎。

IF 1.5 4区医学

Acta gastro-enterologica Belgica Pub Date : 2024-01-01 DOI: 10.51821/87.1.11378

G Van Roey, W Goos, C Claessens, A Hoorens, W Verlinden, J Schouten

引用次数: 0

A lower gastrointestinal bleeding in a haemodialysis patient as a potential precursor of small bowel ischaemia. 血液透析患者的下消化道出血是小肠缺血的潜在前兆。

IF 1.5 4区医学

Acta gastro-enterologica Belgica Pub Date : 2024-01-01 DOI: 10.51821/87.1.12315

K Ferdinande, D Tate, D De Looze

引用次数: 0

Fulminant ectopic Cushing's syndrome caused by metastatic small intestine neuroendocrine tumour - a case report and review of the literature. 转移性小肠神经内分泌肿瘤引起的充血性异位库欣综合征--病例报告和文献综述。

IF 1.5 4区医学

Acta gastro-enterologica Belgica Pub Date : 2024-01-01 DOI: 10.51821/87.1.11872

B Alliet, C Severi, T Veekmans, J Cuypers, H Topal, C M Deroose, T Roskams, M Bex, J Dekervel

{"title":"Fulminant ectopic Cushing's syndrome caused by metastatic small intestine neuroendocrine tumour - a case report and review of the literature.","authors":"B Alliet, C Severi, T Veekmans, J Cuypers, H Topal, C M Deroose, T Roskams, M Bex, J Dekervel","doi":"10.51821/87.1.11872","DOIUrl":"10.51821/87.1.11872","url":null,"abstract":"Cushing's syndrome (CS) secondary to adrenocorticotropic hormone (ACTH) producing tumours is a severe condition with a challenging diagnosis. Ectopic ACTH-secretion often involves neuroendocrine tumours (NET) in the respiratory tract. ACTH-secreting small intestine neuro-endocrine tumours (siNET) are extremely rare entities barely reported in literature. This review is illustrated by the case of a 75-year old woman with fulminant ectopic CS caused by a ACTH-secreting metastatic siNET. Severe hypokalemia, fluid retention and refractory hypertension were the presenting symptoms. Basal and dynamic laboratory studies were diagnostic for ACTH-dependent CS. Extensive imaging studies of the pituitary and thorax-abdomen areas were normal, while [68Ga]Ga-DOTATATE PET-CT revealed increased small intestine uptake in the left iliac fossa. The hypercortisolism was well controlled with somatostatin analogues, after which a debulking resection of the tumour was performed. Pathological investigation confirmed a well-differentiated NET with sporadic ACTH immunostaining and post-operative treatment with somatostatin analogues was continued with favourable disease control.","PeriodicalId":7322,"journal":{"name":"Acta gastro-enterologica Belgica","volume":null,"pages":null},"PeriodicalIF":1.5,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140020734","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Microscopic colitis related to food supplement containing turmeric: a review of 3 cases. 与含姜黄的食品补充剂有关的显微结肠炎：3 例病例回顾。

IF 1.5 4区医学

Acta gastro-enterologica Belgica Pub Date : 2024-01-01 DOI: 10.51821/87.1.12371

L Ponselet, J-M Ghilain, M Schapira

引用次数: 0

Position statement on how can we can implement the Greendeal in our gastrointestinal and gastrointestinal endoscopy department in Belgium. 关于如何在比利时的胃肠道和胃内窥镜检查部门实施 "绿色通道 "的立场声明。

IF 1.5 4区医学

Acta gastro-enterologica Belgica Pub Date : 2024-01-01 DOI: 10.51821/87.1.12500

M Aerts, H Reynaert, P Roelandt, P Caenepeel, P Dewint, A Lemmers, I Colle

{"title":"Position statement on how can we can implement the Greendeal in our gastrointestinal and gastrointestinal endoscopy department in Belgium.","authors":"M Aerts, H Reynaert, P Roelandt, P Caenepeel, P Dewint, A Lemmers, I Colle","doi":"10.51821/87.1.12500","DOIUrl":"10.51821/87.1.12500","url":null,"abstract":"The importance to reach the target to be carbon net zero by 2050, as presented by the European Commission in the European Green Deal, cannot be overestimated. In a current endoscopy world, where single use has found its place and techniques are constantly evolving, it will be a challenge to reach these goals. How can we reconcile this evolution to a carbon neutral status by 2050 without compromising patients care, clinical standards and training needs? The European Society of Gastrointestinal Endoscopy (ESGE) together with the European Society of Gastroenterology and Endoscopy Nurses and Associates (ESGENA) recently published a position statement (1) whereas in the UK there is the work from the green endoscopy group (2) in line with the strategy of the British Society of Gastroenterology (BSG) on sustainability (3). In Flanders, a project called \"greendeal in duurzame zorg\" had its kick off in March 2023 (4) so it is about time that we in Belgium, as gastroenterologists, start with tangible actions to a more sustainable daily practice. We wrote this position statement in cooperation with the Vlaamse Vereniging voor Gastro-Enterologie (VVGE), the Société royale belge de Gastro-entérologie (SRBGE) and the Belgian Society of Gastrointestinal Endoscopy (BSGIE). We will also work together in the coming years to continue to motivate our members to work on these initiatives and to co-opt new projects within the framework of the greendeal.","PeriodicalId":7322,"journal":{"name":"Acta gastro-enterologica Belgica","volume":null,"pages":null},"PeriodicalIF":1.5,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140020739","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Stauffer syndrome : a rare paraneoplastic complication of renal cell carcinoma to be kept in mind. Case report and literature survey. Stauffer 综合征：肾细胞癌罕见的副肿瘤性并发症，值得关注。病例报告和文献调查。

IF 1.5 4区医学

Acta gastro-enterologica Belgica Pub Date : 2024-01-01 DOI: 10.51821/87.1.11402

M Deliège, B Bastens, G Matus, N Blétard, G Houbiers, A Courtois, C Focan

引用次数: 0