Acta gastro-enterologica Belgica最新文献_第3页

Decreased incidence and shift in stage distribution for colorectal cancers in Belgium during the COVID-19 pandemic. 在2019冠状病毒病大流行期间，比利时结直肠癌发病率下降，分期分布发生变化。

IF 1.3 4区医学

Acta gastro-enterologica Belgica Pub Date : 2024-10-01 DOI: 10.51821/87.4.13081

S Janssens, K Van Herck, H M Peacock, F Giusti, G Silversmit, N Van Damme, L Van Eycken

{"title":"Decreased incidence and shift in stage distribution for colorectal cancers in Belgium during the COVID-19 pandemic.","authors":"S Janssens, K Van Herck, H M Peacock, F Giusti, G Silversmit, N Van Damme, L Van Eycken","doi":"10.51821/87.4.13081","DOIUrl":"https://doi.org/10.51821/87.4.13081","url":null,"abstract":"Background and study aims: The COVID-19 pandemic substantially impacted the healthcare system and society in 2020. This study assessed its possible impact on occurrence and stage of colorectal cancer diagnoses in Belgium.Methods: Population-based data from the Belgian Cancer Registry were used to extrapolate 2017-2019 trends in incidence and stage distribution to expected counts for 2020 that were subsequently compared to the observed values. Stage-specific predictions were corrected to account for the overall decline in diagnoses.Results: In 2020, 705 fewer than expected invasive and 255 fewer in situ colorectal cancers were diagnosed. For colon cancer, significant declines were observed in all genders and regions, mainly in the screening age group and in age 75+. For rectal cancers, there was only a significant decline in the latter two groups. Colon cancer pStage distribution did not change significantly. In situ rectal tumors showed a relative decline in Flanders and in the screening age group. In the latter group, more than expected cStage III rectal cancers were observed in women.Conclusions: The excess decline in in situ rectal cancers is likely attributable to the temporary suspension of the colorectal screening program during the first pandemic wave. The overall decline in colon and rectal cancer incidence in Belgium in 2020 was not accompanied by a stage shift. Longer-term effects or impact on clinically relevant outcomes cannot be excluded.","PeriodicalId":7322,"journal":{"name":"Acta gastro-enterologica Belgica","volume":"87 4","pages":"445-455"},"PeriodicalIF":1.3,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142913579","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Evaluation of the adherence of patients with chronic inflammatory bowel diseases to a PRO telemonitoring using connected devices: a prospective monocentric study. 评估慢性炎症性肠病患者对使用连接设备的PRO远程监测的依从性：一项前瞻性单中心研究

IF 1.3 4区医学

Acta gastro-enterologica Belgica Pub Date : 2024-10-01 DOI: 10.51821/87.4.13449

N Delhougne, L Monin, S Vieujean, C Van Kemseke, C Reenaers, O Warling, E Louis

{"title":"Evaluation of the adherence of patients with chronic inflammatory bowel diseases to a PRO telemonitoring using connected devices: a prospective monocentric study.","authors":"N Delhougne, L Monin, S Vieujean, C Van Kemseke, C Reenaers, O Warling, E Louis","doi":"10.51821/87.4.13449","DOIUrl":"https://doi.org/10.51821/87.4.13449","url":null,"abstract":"Background and study aims: Monitoring the symptoms of inflammatory bowel diseases (IBD) patients is now frequently made in the form of patient reported outcomes (PRO), rather than historical clinical activity scores. Unlike several chronic diseases, the role of telemonitoring in IBD has not yet been defined, particularly in terms of patient compliance with remote monitoring; the aim of our study was to assess patient compliance with digital monitoring of PRO as part of routine medical follow-up.Patients and methods: we performed a monocentric prospective study in the Gastroenterology Unit of Liège's University Hospital between May 2023 and February 2024. Adherence was considered optimal if 50% of the recordings planned for the duration of the follow-up were carried out.Results: 31% of the patients included achieved at least 50% total encoding of their PRO over the 9 months of follow-up. The main cause of failure cited by patients was technical difficulties, well ahead of poor motivation. The overall satisfaction of practitioners and patients was generally good. Male gender was the only factor associated with adherence.Conclusion: Overall adherence to PRO telemonitoring in IBD was around 40% and was mainly impaired by technical difficulties. Despite this, both patients and healthcare professionals found this type of monitoring relevant.","PeriodicalId":7322,"journal":{"name":"Acta gastro-enterologica Belgica","volume":"87 4","pages":"457-467"},"PeriodicalIF":1.3,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142913604","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Aspiration thrombectomy of the hepatic veins in Budd Chiari Syndrome. Budd - Chiari综合征肝静脉穿刺取栓术。

IF 1.3 4区医学

Acta gastro-enterologica Belgica Pub Date : 2024-10-01 DOI: 10.51821/87.4.13145

C Geens, W J Kwanten, S Francque, T van der Zijden, M Voormolen, T Jardinet

引用次数: 0

Fatal acute pulmonary embolism following endoscopic cyanoacrylate injection for gastric fundal varices. 胃底静脉曲张内窥镜注射氰基丙烯酸酯后致死性急性肺栓塞。

IF 1.3 4区医学

Acta gastro-enterologica Belgica Pub Date : 2024-10-01 DOI: 10.51821/87.4.13020

C Harth, P De Mulder, S Raevens, K Ferdinande, P Hindryckx, A Geerts, H Van Vlierberghe, P Vanlangenhove, X Verhelst

引用次数: 0

Atypical anal itching lesion associated with a protruding rectal polyp. 非典型肛门瘙痒病变伴直肠息肉突出。

IF 1.3 4区医学

Acta gastro-enterologica Belgica Pub Date : 2024-10-01 DOI: 10.51821/87.4.13631

Q Binet, A -P Draguet, L Stainier

引用次数: 0

Treatment patterns and outcomes of patients with complex Crohn's perianal fistula in five European countries: the PREFACE study. 5个欧洲国家复杂克罗恩肛周瘘患者的治疗模式和结果：前言研究

IF 1.3 4区医学

Acta gastro-enterologica Belgica Pub Date : 2024-10-01 DOI: 10.51821/87.4.13143

M Ferrante, L Siproudhis, G Poggioli, M Reinshagen, S Milicevic, M Roset, N BentEnnakhil, A Fernandez-Nistal, J Panes

{"title":"Treatment patterns and outcomes of patients with complex Crohn's perianal fistula in five European countries: the PREFACE study.","authors":"M Ferrante, L Siproudhis, G Poggioli, M Reinshagen, S Milicevic, M Roset, N BentEnnakhil, A Fernandez-Nistal, J Panes","doi":"10.51821/87.4.13143","DOIUrl":"https://doi.org/10.51821/87.4.13143","url":null,"abstract":"Background and study aims: Crohn's disease (CD) is often complicated by perianal fistulas or abscesses that worsen patient's quality of life, with 52-88% of CD-related perianal fistulas (CPFs) being complex. This retrospective study describes sociodemographic characteristics, treatment patterns and outcomes of patients with complex CPFs in five European countries.Patients and methods: PREFACE is a multi-national medical chart review study of CD patients who started medical or surgical treatment for a new episode of complex CPFs between September 2011 and September 2014 (index date). Effectiveness outcomes were assessed as fistula remission rates based on fistula drainage assessment. The most recent assessments prior to each timepoint were used to calculate fistula remission rates.Results: In total, 372 patients (51.3% male, mean age at index date 37.8 years) with 498 complex CPFs between index date and end of data collection were included. A quarter of patients with CPF already had perianal fistulas at CD diagnosis. Of the complex index CPFs, 39.8% were treated with antitumour necrosis factor, 33.3% with antibiotics and 16.3% with immunosuppressants. At least one surgery was performed for 93.8% of complex CPFs. By end of follow-up (median (IQR) 6.0 (5.2, 6.9) years), 61.2% of complex CPFs were not draining anymore. Fistula remission rate at patient level was 28.0% after 6 months, 35.2% after 12 months and 64.8% overall.Conclusions: Current therapeutic algorithms for CPFs are not successful in a considerable proportion of patients. Improved therapeutic strategies and new treatment options are required to achieve better outcomes in complex CPFs.","PeriodicalId":7322,"journal":{"name":"Acta gastro-enterologica Belgica","volume":"87 4","pages":"494-504"},"PeriodicalIF":1.3,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142913701","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Essential to read from the editorial board. 必须从编辑委员会阅读。

IF 1.3 4区医学

Acta gastro-enterologica Belgica Pub Date : 2024-10-01 DOI: 10.51821/87.4.14030

C Reenaers, H De Schepper

引用次数: 0

Performance of novices in Endoscopic Submucosal Dissection starting directly in human patients under direct supervision of an expert endoscopist. 在内镜专家的直接监督下，在人类患者中直接开始内镜粘膜下解剖的新手表现。

IF 1.3 4区医学

Acta gastro-enterologica Belgica Pub Date : 2024-10-01 DOI: 10.51821/87.4.13604

J Bekaert, S Van Langendonck, N Van Heddegem, J Haringsma, P Dewint

{"title":"Performance of novices in Endoscopic Submucosal Dissection starting directly in human patients under direct supervision of an expert endoscopist.","authors":"J Bekaert, S Van Langendonck, N Van Heddegem, J Haringsma, P Dewint","doi":"10.51821/87.4.13604","DOIUrl":"https://doi.org/10.51821/87.4.13604","url":null,"abstract":"Background and study aim: The ESGE curriculum guideline on training in ESD advises an extensive experience in animal models before commencing ESD training on humans. However, the evidence on which this recommendation is based, is rather limited. In this study we evaluate the performance of novices in ESD during their one-year training period; with continuous supervision of an endoscopist with extensive experience in ESD.Patients and methods: During a 6.5 years period, all ESD procedures performed by an expert endoscopist (eESD) or by one of the 3 novices (sESD), in a single non-academic center, were retrospectively collected. Primary outcome parameters were rate of en-bloc resection and clinically relevant adverse events. The secondary outcome was R0 resection, recurrence rate and delayed adverse events.Results: In total 210 ESD procedures were included. Of these 97 sESD (46.2%), were performed by a novice endoscopist under supervision and 113 eESD (53,8%) by an expert. En-bloc resection rate was 99.1% vs 99% (p = ns), R0 resection rate was 80.5 % vs 79.4 % (p=ns). Clinically relevant complications 14.2% vs 6.2 % (p = 0.04) and severe complications 4.4% vs 2.1% (p=ns). Perforation was the most frequent reported serious complication. Three patients in the eESD group versus one in the other group needed additionally surgery due to a complication (p=ns). Recurrence rate was 2.2% for eESD and 1.3 % for sESD (p=ns).Conclusion: This retrospective analysis demonstrates that learning ESD in humans without extensive prior animal model training is safe and feasible, on the condition that continuous supervision by an expert is provided.","PeriodicalId":7322,"journal":{"name":"Acta gastro-enterologica Belgica","volume":"87 4","pages":"478-483"},"PeriodicalIF":1.3,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142913621","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Profuse diarrhea after autologous stem cell transplantation for peripheral T-cell lymphoma, not otherwise specified: a case report. 自体干细胞移植治疗外周t细胞淋巴瘤后大量腹泻，无其他特殊说明：1例报告。

IF 1.3 4区医学

Acta gastro-enterologica Belgica Pub Date : 2024-10-01 DOI: 10.51821/87.4.12974

K Gysen, M Staessens, E De Backer, A Driessen, K Krishnadath, E Macken, A Jauregui, S Bouhadan, H De Schepper, M Somers

引用次数: 0

Are nucleot(s)ide analogues a negative factor for HBsAg seroconversion in acute hepatitis B? 核苷酸类似物是急性乙型肝炎 HBsAg 血清转换的阴性因素吗？

IF 1.3 4区医学

Acta gastro-enterologica Belgica Pub Date : 2024-07-01 DOI: 10.51821/87.3.12462

M F Keser, M A Erdogan, O Yıldırım

{"title":"Are nucleot(s)ide analogues a negative factor for HBsAg seroconversion in acute hepatitis B?","authors":"M F Keser, M A Erdogan, O Yıldırım","doi":"10.51821/87.3.12462","DOIUrl":"https://doi.org/10.51821/87.3.12462","url":null,"abstract":"Background and study aim: There are several studies comparing patients treated with lamivudine and those not given antiviral therapy in acute hepatitis B. Some of these studies showed that antiviral treatment significantly contributed to survival, whereas one other study suggested that antiviral treatment had no effect. The aim of this study was to investigate the efficacy of tenofovir disoproxil fumarate (TDF) therapy and its effect on HBsAg seroconversion in patients with acute viral hepatitis B.Patients and methods: The files of 126 patients who were under follow-up for acute HBV infection in the Department of Gastroenterology were analyzed retrospectively. Demographic data, molecular, ELISA, and biochemistry tests at the time of diagnosis and in the follow-up, period were evaluated using the hospital automation system.Results: The rate of chronicity of HBV was found to be higher in the TDF group than in the group without antiviral treatment. The rate of protective anti-HBs acquisition was found to be lower in the TDF group (p<0.05).Conclusion: Antiviral treatment with TDF in acute HBV infection may increase the rate of chronicity. It may reduce the development of natural immunity. Further studies are warranted.","PeriodicalId":7322,"journal":{"name":"Acta gastro-enterologica Belgica","volume":"87 3","pages":"367-371"},"PeriodicalIF":1.3,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142455740","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0