Acta gastro-enterologica Belgica最新文献_第2页

Cat Scratch Colon. 猫抓结肠。

IF 1.2 4区医学

Acta gastro-enterologica Belgica Pub Date : 2025-07-01 DOI: 10.51821/88.3.14351

J Vandewalle, L Thijs, F Janssens, H Vandyck, D Walgraeve

引用次数: 0

When blood mimics bile: A case of haemorrhagic cholecystitis masquerading as biliary pancreatitis. 当血模拟胆汁：出血性胆囊炎伪装成胆道性胰腺炎1例。

IF 1.2 4区医学

Acta gastro-enterologica Belgica Pub Date : 2025-07-01 DOI: 10.51821/88.3.14249

A Vertessen, J Dutré, J Weyler, M Simoens, T Apers, J Lenz

{"title":"When blood mimics bile: A case of haemorrhagic cholecystitis masquerading as biliary pancreatitis.","authors":"A Vertessen, J Dutré, J Weyler, M Simoens, T Apers, J Lenz","doi":"10.51821/88.3.14249","DOIUrl":"https://doi.org/10.51821/88.3.14249","url":null,"abstract":"Background: Cholecystitis and pancreatitis are frequent indications for hospitalization in gastroenterology and hepatology, predominantly due to cholelithiasis. Standard management strategies with imaging and cholecystectomy are common practice. This case report highlights the importance of considering atypical causes in patients presenting with symptoms suggestive of cholecystitis and pancreatitis.Case report: A female patient presented repeatedly to the emergency department with atypical ultrasound findings suggestive of cholecystitis with secondary pancreatitis. Following an episode of severe upper gastrointestinal bleeding, a diagnosis of haemobilia with secondary pancreatitis was established.Discussion: This case illustrates that haemobilia can present with symptoms resembling calculous cholecystitis and biliary pancreatitis. Diagnosis can be challenging, especially in the absence of recent procedures or known malignancy. Quincke's triad-pain, jaundice, and bleeding-is observed in only a third of cases.Conclusion: Haemobilia, though rare, is an important differential diagnosis in cases of upper gastrointestinal bleeding and biliary obstruction. A multidisciplinary approach is essential for prompt diagnosis and appropriate treatment.","PeriodicalId":7322,"journal":{"name":"Acta gastro-enterologica Belgica","volume":"88 3","pages":"285-287"},"PeriodicalIF":1.2,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145285317","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Simultaneous portosystemic shunt and proximal splenic artery embolization for patients with therapy-refractory hepatic encephalopathy at risk of portal hypertensive complications. 同时门静脉分流和脾近端动脉栓塞治疗难治性肝性脑病并发门静脉高压并发症的风险。

IF 1.2 4区医学

Acta gastro-enterologica Belgica Pub Date : 2025-07-01 DOI: 10.51821/88.3.14066

A Lemaitre, S Nullens, M Van Herck, T Jardinet

{"title":"Simultaneous portosystemic shunt and proximal splenic artery embolization for patients with therapy-refractory hepatic encephalopathy at risk of portal hypertensive complications.","authors":"A Lemaitre, S Nullens, M Van Herck, T Jardinet","doi":"10.51821/88.3.14066","DOIUrl":"https://doi.org/10.51821/88.3.14066","url":null,"abstract":"Background: Hepatic encephalopathy (HE) is a well-known complication of cirrhosis. When HE recurs despite optimal treatment or without a clear precipitant, a portosystemic shunt may be the culprit. We present a case of therapy-refractory HE caused by a spontaneous portosystemic shunt (SPSS).Clinical case: A 69-year-old male with MASLD-related cirrhosis, with a medical history of biliopancreatic diversion and variceal bleeding, presented with his fifth episode of HE despite maximal pharmacological treatment. Initial lab tests and infectious screen were negative. Abdominal CT scan showed a paraesophageal shunt, supplied by the coronary vein. To address HE, SPSS closure was planned. Since SPSS closure could aggravate PHT and subsequently increase paracentesis frequency or induce variceal bleeding, this was combined with a proximal splenic artery embolization (pSAE). pSAE after SPSS closure resulted in a reduction of hepatic venous pressure gradient (HVPG) from 21mmHg to 15 mmHg. HE symptoms resolved, pharmacological treatment was stopped, and paracentesis became less frequent. Weeks later, the patient was readmitted with abdominal pain, and CT confirmed splenic infarction. Recurrent spontaneous bacterial peritonitis necessitated splenectomy, which was complicated by hemorrhage, septic shock, and death.Conclusion: This case highlights the potential of combining SPSS closure and pSAE, two procedures that have not been combined before to our knowledge, to effectively reduce HE and HVPG, enabling cessation of anti-encephalopathic therapy and lowering paracentesis frequency. However, altered vascular anatomy can lead to complications such as splenic infarction. Although splenic infarction occurred as a complication, we believe this novel combined procedure warrants further investigation.","PeriodicalId":7322,"journal":{"name":"Acta gastro-enterologica Belgica","volume":"88 3","pages":"281-284"},"PeriodicalIF":1.2,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145285260","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

A rare cause of B-symptoms and polyarthritis. b型症状和多发性关节炎的罕见病因。

IF 1.2 4区医学

Acta gastro-enterologica Belgica Pub Date : 2025-07-01 DOI: 10.51821/88.3.14745

S Arnaert, E De Wit, F D'Heygere

引用次数: 0

Efficacy and safety of capecitabine-temozolomide (CAPTEM) regimen in patients with neuroendocrine neoplasms - experience from NETwerk, a Belgian ENETS Center of Excellence. 卡培他滨-替莫唑胺（CAPTEM）治疗神经内分泌肿瘤患者的疗效和安全性——来自比利时ENETS卓越中心NETwerk的经验

IF 1.2 4区医学

Acta gastro-enterologica Belgica Pub Date : 2025-04-01 DOI: 10.51821/88.1.13722

C Lambrechts, S Chhajlani, O Islam, L Verbruggen, C De Weerdt, L Mariën, M Simoens, M Ulenaers, D Galdermans, W Demey, I Van der Massen, W Lybaert, T Vandamme

{"title":"Efficacy and safety of capecitabine-temozolomide (CAPTEM) regimen in patients with neuroendocrine neoplasms - experience from NETwerk, a Belgian ENETS Center of Excellence.","authors":"C Lambrechts, S Chhajlani, O Islam, L Verbruggen, C De Weerdt, L Mariën, M Simoens, M Ulenaers, D Galdermans, W Demey, I Van der Massen, W Lybaert, T Vandamme","doi":"10.51821/88.1.13722","DOIUrl":"10.51821/88.1.13722","url":null,"abstract":"Neuroendocrine neoplasms (NEN) are rare tumors originating from neuroendocrine cells, commonly found in the gastrointestinal tract and the pulmonary tract. Metastatic welldifferentiated neuroendocrine tumors (NET) grade 3 present unique challenges, as they are positioned between the more indolent NET grade 1-2 and the aggressive neuroendocrine carcinomas (NEC). Due to the scarcity of data regarding the optimal systemic treatment for metastatic NET grade 3 and aggressive NET grade 2 subtypes, guidelines remain inconclusive. This retrospective study analyzed data from the NETwerk database, encompassing patients treated with the capecitabinetemozolomide (CAPTEM) regimen between June 2016 and January 2024. The cohort included patients with NET grades 1-3 and NEC. The study focused on assessing the efficacy and safety of CAPTEM. In total, data from 36 patients was analyzed. The median progression-free survival (mPFS) was 13 months, and median overall survival (mOS) was 17 months. Overall response rate (ORR) was 25.8%, and the disease control rate (DCR) was 67.7%. NET grade 2 patients had the highest mPFS, while NET grade 3 exhibited the most favorable mOS. Subgroup analysis showed that panNEN had superior mPFS and mOS compared to other primary tumor sites, with significant differences in mOS based on NEN type. Safety analysis in 20 patients indicated good tolerance and safety . CAPTEM is an efficient and safe regimen for metastatic NEN, with promising outcomes in NET grade 2-3 patients. The promising findings pave the way for further exploration into various aspects of CAPTEM, to better define its position in the therapeutic landscape of NEN.","PeriodicalId":7322,"journal":{"name":"Acta gastro-enterologica Belgica","volume":"88 2","pages":"119-127"},"PeriodicalIF":1.2,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144273859","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Recommendations for the diagnosis and management of patients with chronic idiopathic diarrhea: Belgian multidisciplinary expert discussion based on a modified Delphi method. 慢性特发性腹泻患者的诊断和管理建议：比利时多学科专家讨论基于改进的德尔菲法。

IF 1.3 4区医学

Acta gastro-enterologica Belgica Pub Date : 2025-04-01 DOI: 10.51821/88.1.13772

T Vanuytsel, J Arts, V Casneuf, F de Clerck, D De Looze, H Deschepper, K Geboes, M Hiele, T Holvoet, H Louis, S Kindt, P Latour, F Mokaddem, S Nullens, H Piessevaux, M Surmont, J Tack, R Bisschops

{"title":"Recommendations for the diagnosis and management of patients with chronic idiopathic diarrhea: Belgian multidisciplinary expert discussion based on a modified Delphi method.","authors":"T Vanuytsel, J Arts, V Casneuf, F de Clerck, D De Looze, H Deschepper, K Geboes, M Hiele, T Holvoet, H Louis, S Kindt, P Latour, F Mokaddem, S Nullens, H Piessevaux, M Surmont, J Tack, R Bisschops","doi":"10.51821/88.1.13772","DOIUrl":"https://doi.org/10.51821/88.1.13772","url":null,"abstract":"Background: Chronic diarrhea is one of the more common reasons for referral to a gastro-enterologist. Chronic diarrhea can have a broad range of causes, making it a disease entity with a very extensive differential diagnosis. In a proportion of patients, however, a cause for the chronic diarrhea cannot be found and these patients are said to have chronic idiopathic diarrhea (CID).Methods: A Delphi model was used to establish a diagnostic strategy for patients presenting with chronic diarrhea that maximizes the chance for a positive diagnosis while minimizing the number and invasiveness of the investigations. In addition, the participating experts sought consensus on the different treatment options that can be used in these patients.Results: While a general consensus was reached on the required diagnostic tests for CID, marked differences were observed on the treatment preferences and strategies for these patients among the different experts. The main reason for this is the lack of solid scientific evidence with the different treatment options in this setting (i.e., most data have been generated in patients with IBS-D).Conclusion: the Delphi-like process that was used for this initiative proved to be a useful vehicle to fuel discussions on the management of CID among experts with different backgrounds and to sketch the current clinical practice.","PeriodicalId":7322,"journal":{"name":"Acta gastro-enterologica Belgica","volume":"88 2","pages":"179-194"},"PeriodicalIF":1.3,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144273865","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Esophageal Lichen Planus: a Narrative Review of the Literature. 食管扁平苔藓：文献综述。

IF 1.3 4区医学

Acta gastro-enterologica Belgica Pub Date : 2025-04-01 DOI: 10.51821/88.1.13966

A Oosterbosch, P De Haes, G De Hertogh, J Tack, T Vanuytsel

{"title":"Esophageal Lichen Planus: a Narrative Review of the Literature.","authors":"A Oosterbosch, P De Haes, G De Hertogh, J Tack, T Vanuytsel","doi":"10.51821/88.1.13966","DOIUrl":"10.51821/88.1.13966","url":null,"abstract":"Background: Lichen planus is a mucocutaneous chronic inflammatory disorder that can also affect the esophagus in a minority of patients. Esophageal lichen planus (ELP) is likely an underdiagnosed and underreported disease entity, although it can lead to significant morbidity with esophageal stenosis or malignant transformation.Methods: A non-systematic search of Pubmed was performed using search terms 'esophageal lichen planus' and variants thereof combined with terms related to prevalence, diagnosis, and management.Results: The cutaneous and oral forms of lichen planus are relatively common, but certain mucosal forms such as genital lichen planus are rare and esophageal planus (also a mucosal form) is very rare. ELP occurs predominantly in middle-aged women. Current guidelines regarding lichen planus do not mention a screening strategy for ELP. Diagnosis of ELP is based on endoscopic and histopathological criteria. The foremost complication of ELP is formation of esophageal strictures. Malignant transformation of ELP to squamous cell carcinoma, although rare, has also been reported. We summarize the current evidence regarding optimal management of ELP.Conclusion: Even if esophageal lichen planus is a rare cause of esophageal strictures, it is important to raise awareness of this condition among gastroenterologists and endoscopists. The cornerstone of ELP treatment is an anti-inflammatory agent in conjunction with endoscopic dilatation of strictures. Further research is needed to devise an evidence-based treatment algorithm that describes the optimal anti-inflammatory drug in different stages/severities of ELP.","PeriodicalId":7322,"journal":{"name":"Acta gastro-enterologica Belgica","volume":"88 2","pages":"129-140"},"PeriodicalIF":1.3,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144273860","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Gliptin induced acute pancreatitis: a literature review. 格列汀诱导急性胰腺炎的文献综述。

IF 1.3 4区医学

Acta gastro-enterologica Belgica Pub Date : 2025-04-01 DOI: 10.51821/88.1.13722

G Jaya Pragadeesh, Sheik Asik Abu Sali, S Rajesh Kumar, Dhanashri Babu, D Dheepthi

引用次数: 0

Acute hepatitis E-related Guillain-Barré syndrome. 急性戊型肝炎相关格林-巴利综合征。

IF 1.3 4区医学

Acta gastro-enterologica Belgica Pub Date : 2025-04-01 DOI: 10.51821/88.1.13825

D Naudts, B Van Overberghe, F De Maeyer, M Peeters, T Vanwolleghem

引用次数: 0

Essential reading from the editorial board. 编辑委员会的重要读物。

IF 1.3 4区医学

Acta gastro-enterologica Belgica Pub Date : 2025-04-01 DOI: 10.51821/88.1.14571

H De Schepper, A Marot

引用次数: 0