Acta gastro-enterologica Belgica最新文献_第2页

Atypical anal itching lesion associated with a protruding rectal polyp.

IF 1.3 4区医学

Acta gastro-enterologica Belgica Pub Date : 2024-10-01 DOI: 10.51821/87.4.13631

Q Binet, A -P Draguet, L Stainier

引用次数: 0

Fatal acute pulmonary embolism following endoscopic cyanoacrylate injection for gastric fundal varices.

IF 1.3 4区医学

Acta gastro-enterologica Belgica Pub Date : 2024-10-01 DOI: 10.51821/87.4.13020

C Harth, P De Mulder, R Raevens, K Ferdinande, P Hindryckx, A Geerts, H Van Vlierberghe, P Vanlangenhove, X Verhelst

引用次数: 0

Treatment patterns and outcomes of patients with complex Crohn's perianal fistula in five European countries: the PREFACE study.

IF 1.3 4区医学

Acta gastro-enterologica Belgica Pub Date : 2024-10-01 DOI: 10.51821/87.4.13143

M Ferrante, L Siproudhis, G Poggioli, M Reinshagen, S Milicevic, M Roset, N BentEnnakhil, A Fernandez-Nistal, J Panes

{"title":"Treatment patterns and outcomes of patients with complex Crohn's perianal fistula in five European countries: the PREFACE study.","authors":"M Ferrante, L Siproudhis, G Poggioli, M Reinshagen, S Milicevic, M Roset, N BentEnnakhil, A Fernandez-Nistal, J Panes","doi":"10.51821/87.4.13143","DOIUrl":"https://doi.org/10.51821/87.4.13143","url":null,"abstract":"Background and study aims: Crohn's disease (CD) is often complicated by perianal fistulas or abscesses that worsen patient's quality of life, with 52-88% of CD-related perianal fistulas (CPFs) being complex. This retrospective study describes sociodemographic characteristics, treatment patterns and outcomes of patients with complex CPFs in five European countries.Patients and methods: PREFACE is a multi-national medical chart review study of CD patients who started medical or surgical treatment for a new episode of complex CPFs between September 2011 and September 2014 (index date). Effectiveness outcomes were assessed as fistula remission rates based on fistula drainage assessment. The most recent assessments prior to each timepoint were used to calculate fistula remission rates.Results: In total, 372 patients (51.3% male, mean age at index date 37.8 years) with 498 complex CPFs between index date and end of data collection were included. A quarter of patients with CPF already had perianal fistulas at CD diagnosis. Of the complex index CPFs, 39.8% were treated with antitumour necrosis factor, 33.3% with antibiotics and 16.3% with immunosuppressants. At least one surgery was performed for 93.8% of complex CPFs. By end of follow-up (median (IQR) 6.0 (5.2, 6.9) years), 61.2% of complex CPFs were not draining anymore. Fistula remission rate at patient level was 28.0% after 6 months, 35.2% after 12 months and 64.8% overall.Conclusions: Current therapeutic algorithms for CPFs are not successful in a considerable proportion of patients. Improved therapeutic strategies and new treatment options are required to achieve better outcomes in complex CPFs.","PeriodicalId":7322,"journal":{"name":"Acta gastro-enterologica Belgica","volume":"87 4","pages":"494-504"},"PeriodicalIF":1.3,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142913701","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Essential to read from the editorial board.

IF 1.3 4区医学

Acta gastro-enterologica Belgica Pub Date : 2024-10-01 DOI: 10.51821/87.4.14030

C Reenaers, H De Schepper

引用次数: 0

Performance of novices in Endoscopic Submucosal Dissection starting directly in human patients under direct supervision of an expert endoscopist.

IF 1.3 4区医学

Acta gastro-enterologica Belgica Pub Date : 2024-10-01 DOI: 10.51821/87.4.13604

J Bekaert, S Van Langendonck, N Van Heddegem, J Haringsma, P Dewint

{"title":"Performance of novices in Endoscopic Submucosal Dissection starting directly in human patients under direct supervision of an expert endoscopist.","authors":"J Bekaert, S Van Langendonck, N Van Heddegem, J Haringsma, P Dewint","doi":"10.51821/87.4.13604","DOIUrl":"https://doi.org/10.51821/87.4.13604","url":null,"abstract":"Background and study aim: The ESGE curriculum guideline on training in ESD advises an extensive experience in animal models before commencing ESD training on humans. However, the evidence on which this recommendation is based, is rather limited. In this study we evaluate the performance of novices in ESD during their one-year training period; with continuous supervision of an endoscopist with extensive experience in ESD.Patients and methods: During a 6.5 years period, all ESD procedures performed by an expert endoscopist (eESD) or by one of the 3 novices (sESD), in a single non-academic center, were retrospectively collected. Primary outcome parameters were rate of en-bloc resection and clinically relevant adverse events. The secondary outcome was R0 resection, recurrence rate and delayed adverse events.Results: In total 210 ESD procedures were included. Of these 97 sESD (46.2%), were performed by a novice endoscopist under supervision and 113 eESD (53,8%) by an expert. En-bloc resection rate was 99.1% vs 99% (p = ns), R0 resection rate was 80.5 % vs 79.4 % (p=ns). Clinically relevant complications 14.2% vs 6.2 % (p = 0.04) and severe complications 4.4% vs 2.1% (p=ns). Perforation was the most frequent reported serious complication. Three patients in the eESD group versus one in the other group needed additionally surgery due to a complication (p=ns). Recurrence rate was 2.2% for eESD and 1.3 % for sESD (p=ns).Conclusion: This retrospective analysis demonstrates that learning ESD in humans without extensive prior animal model training is safe and feasible, on the condition that continuous supervision by an expert is provided.","PeriodicalId":7322,"journal":{"name":"Acta gastro-enterologica Belgica","volume":"87 4","pages":"478-483"},"PeriodicalIF":1.3,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142913621","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Profuse diarrhea after autologous stem cell transplantation for peripheral T-cell lymphoma, not otherwise specified: a case report.

IF 1.3 4区医学

Acta gastro-enterologica Belgica Pub Date : 2024-10-01 DOI: 10.51821/87.4.12974

K Gysen, M Staessens, E De Backer, A Driessen, K Krishnadath, E Macken, A Jauregui, S Bouhadan, H De Schepper, M Somers

引用次数: 0

Are nucleot(s)ide analogues a negative factor for HBsAg seroconversion in acute hepatitis B? 核苷酸类似物是急性乙型肝炎 HBsAg 血清转换的阴性因素吗？

IF 1.3 4区医学

Acta gastro-enterologica Belgica Pub Date : 2024-07-01 DOI: 10.51821/87.3.12462

M F Keser, M A Erdogan, O Yıldırım

{"title":"Are nucleot(s)ide analogues a negative factor for HBsAg seroconversion in acute hepatitis B?","authors":"M F Keser, M A Erdogan, O Yıldırım","doi":"10.51821/87.3.12462","DOIUrl":"https://doi.org/10.51821/87.3.12462","url":null,"abstract":"Background and study aim: There are several studies comparing patients treated with lamivudine and those not given antiviral therapy in acute hepatitis B. Some of these studies showed that antiviral treatment significantly contributed to survival, whereas one other study suggested that antiviral treatment had no effect. The aim of this study was to investigate the efficacy of tenofovir disoproxil fumarate (TDF) therapy and its effect on HBsAg seroconversion in patients with acute viral hepatitis B.Patients and methods: The files of 126 patients who were under follow-up for acute HBV infection in the Department of Gastroenterology were analyzed retrospectively. Demographic data, molecular, ELISA, and biochemistry tests at the time of diagnosis and in the follow-up, period were evaluated using the hospital automation system.Results: The rate of chronicity of HBV was found to be higher in the TDF group than in the group without antiviral treatment. The rate of protective anti-HBs acquisition was found to be lower in the TDF group (p<0.05).Conclusion: Antiviral treatment with TDF in acute HBV infection may increase the rate of chronicity. It may reduce the development of natural immunity. Further studies are warranted.","PeriodicalId":7322,"journal":{"name":"Acta gastro-enterologica Belgica","volume":"87 3","pages":"367-371"},"PeriodicalIF":1.3,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142455740","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Combination therapy based on SpyGlass-guided electrohydraulic lithotripsy through cholecystoduodenostomy by lumen-apposing metal stent (SLAMS) for Mirizzi syndrome. 基于 SpyGlass 引导下的电液碎石术和胆囊十二指肠造口术（SLAMS）的联合疗法治疗米利兹综合征。

IF 1.3 4区医学

Acta gastro-enterologica Belgica Pub Date : 2024-07-01 DOI: 10.51821/87.3.12301

V VandenDriessche, P Yengue, J Collin, M Lefebvre

{"title":"Combination therapy based on SpyGlass-guided electrohydraulic lithotripsy through cholecystoduodenostomy by lumen-apposing metal stent (SLAMS) for Mirizzi syndrome.","authors":"V VandenDriessche, P Yengue, J Collin, M Lefebvre","doi":"10.51821/87.3.12301","DOIUrl":"https://doi.org/10.51821/87.3.12301","url":null,"abstract":"Mirizzi syndrome is a rare complication of chronic gallstone disease characterised by the compression of the common bile duct due to an impacted lithiasis in the infundibulum of the gallbladder or cystic duct. In this case study, we discuss an 85-yearold patient who presented with Mirizzi syndrome associated with septic shock. She was not eligible for cholecystectomy due to her advanced age and frailty, requiring a less invasive alternative. Gallbladder drainage was initiated by endoscopic ultrasoundguided cholecystoduodenostomy with a lumen-apposing metal stent (LAMS). Utilising this bulbo-cholecystic stent, SpyGlassguided electrohydraulic lithotripsy (SGEHL) was then performed, resulting in successful extraction of multiple bile stones, including a 20 mm lithiasis that was lodged in the cystic infundibulum. Subsequently, serum bilirubin levels and inflammatory markers were significantly reduced, consistent with resolution of Mirizzi syndrome. The combination of SGEHL and LAMS, designated as SLAMS, represents a novel, minimally invasive intervention for this potentially life-threatening disease.","PeriodicalId":7322,"journal":{"name":"Acta gastro-enterologica Belgica","volume":"87 3","pages":"424-426"},"PeriodicalIF":1.3,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142455742","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Regulatory, diagnostic, and therapeutic roles of microRNAs in chronic liver diseases. 微小核糖核酸在慢性肝病中的调节、诊断和治疗作用。

IF 1.3 4区医学

Acta gastro-enterologica Belgica Pub Date : 2024-07-01 DOI: 10.51821/87.2.12965

Razieh Kazemzadeh, Maryam Kheirollahi, Seyed Ali Mard, Akram Ahangarpour, Feryal Savari

{"title":"Regulatory, diagnostic, and therapeutic roles of microRNAs in chronic liver diseases.","authors":"Razieh Kazemzadeh, Maryam Kheirollahi, Seyed Ali Mard, Akram Ahangarpour, Feryal Savari","doi":"10.51821/87.2.12965","DOIUrl":"https://doi.org/10.51821/87.2.12965","url":null,"abstract":"Fibrogenesis is initially performed during tissue damage to protect the remaining tissues from the progressive death of epithelial cells, infiltration of immune and inflammatory cells, and local degrading enzymes. Inflammation can lead to excessive extracellular matrix deposition by fibroblasts and the induction of fibrosis in many organs, such as the liver. MiRNAs are small noncoding RNAs that mediate mRNA repression or destabilization, leading to translational repression. Owing to the wide range of roles of miRNAs in the development of fibrosis, especially liver fibrosis, many studies have focused on their diagnostic, regulatory, and therapeutic roles. In this study, we used medical science and general databases, including PubMed, Elsevier, Scopus, Nature, and Google Scholar, to find valid studies on the different roles of miRNAs in liver fibrosis. Because a large number of miRNAs with regulatory, diagnostic, and therapeutic roles in diseases associated with liver fibrosis have been identified and reported in this study, special attention to these elements is needed in the future of healthcare systems.","PeriodicalId":7322,"journal":{"name":"Acta gastro-enterologica Belgica","volume":"87 3","pages":"403-412"},"PeriodicalIF":1.3,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142455749","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Small bowel obstruction on food impaction after binge eating. 暴饮暴食后食物嵌塞导致小肠梗阻。

IF 1.3 4区医学

Acta gastro-enterologica Belgica Pub Date : 2024-07-01 DOI: 10.51821/87.3.12506

E Van Eecke, L Crapé, I Colle

引用次数: 0