Acta gastro-enterologica Belgica最新文献

Are nucleot(s)ide analogues a negative factor for HBsAg seroconversion in acute hepatitis B? 核苷酸类似物是急性乙型肝炎 HBsAg 血清转换的阴性因素吗？

IF 1.3 4区医学

Acta gastro-enterologica Belgica Pub Date : 2024-07-01 DOI: 10.51821/87.3.12462

M F Keser, M A Erdogan, O Yıldırım

{"title":"Are nucleot(s)ide analogues a negative factor for HBsAg seroconversion in acute hepatitis B?","authors":"M F Keser, M A Erdogan, O Yıldırım","doi":"10.51821/87.3.12462","DOIUrl":"https://doi.org/10.51821/87.3.12462","url":null,"abstract":"Background and study aim: There are several studies comparing patients treated with lamivudine and those not given antiviral therapy in acute hepatitis B. Some of these studies showed that antiviral treatment significantly contributed to survival, whereas one other study suggested that antiviral treatment had no effect. The aim of this study was to investigate the efficacy of tenofovir disoproxil fumarate (TDF) therapy and its effect on HBsAg seroconversion in patients with acute viral hepatitis B.Patients and methods: The files of 126 patients who were under follow-up for acute HBV infection in the Department of Gastroenterology were analyzed retrospectively. Demographic data, molecular, ELISA, and biochemistry tests at the time of diagnosis and in the follow-up, period were evaluated using the hospital automation system.Results: The rate of chronicity of HBV was found to be higher in the TDF group than in the group without antiviral treatment. The rate of protective anti-HBs acquisition was found to be lower in the TDF group (p<0.05).Conclusion: Antiviral treatment with TDF in acute HBV infection may increase the rate of chronicity. It may reduce the development of natural immunity. Further studies are warranted.","PeriodicalId":7322,"journal":{"name":"Acta gastro-enterologica Belgica","volume":"87 3","pages":"367-371"},"PeriodicalIF":1.3,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142455740","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Combination therapy based on SpyGlass-guided electrohydraulic lithotripsy through cholecystoduodenostomy by lumen-apposing metal stent (SLAMS) for Mirizzi syndrome. 基于 SpyGlass 引导下的电液碎石术和胆囊十二指肠造口术（SLAMS）的联合疗法治疗米利兹综合征。

IF 1.3 4区医学

Acta gastro-enterologica Belgica Pub Date : 2024-07-01 DOI: 10.51821/87.3.12301

V VandenDriessche, P Yengue, J Collin, M Lefebvre

{"title":"Combination therapy based on SpyGlass-guided electrohydraulic lithotripsy through cholecystoduodenostomy by lumen-apposing metal stent (SLAMS) for Mirizzi syndrome.","authors":"V VandenDriessche, P Yengue, J Collin, M Lefebvre","doi":"10.51821/87.3.12301","DOIUrl":"https://doi.org/10.51821/87.3.12301","url":null,"abstract":"Mirizzi syndrome is a rare complication of chronic gallstone disease characterised by the compression of the common bile duct due to an impacted lithiasis in the infundibulum of the gallbladder or cystic duct. In this case study, we discuss an 85-yearold patient who presented with Mirizzi syndrome associated with septic shock. She was not eligible for cholecystectomy due to her advanced age and frailty, requiring a less invasive alternative. Gallbladder drainage was initiated by endoscopic ultrasoundguided cholecystoduodenostomy with a lumen-apposing metal stent (LAMS). Utilising this bulbo-cholecystic stent, SpyGlassguided electrohydraulic lithotripsy (SGEHL) was then performed, resulting in successful extraction of multiple bile stones, including a 20 mm lithiasis that was lodged in the cystic infundibulum. Subsequently, serum bilirubin levels and inflammatory markers were significantly reduced, consistent with resolution of Mirizzi syndrome. The combination of SGEHL and LAMS, designated as SLAMS, represents a novel, minimally invasive intervention for this potentially life-threatening disease.","PeriodicalId":7322,"journal":{"name":"Acta gastro-enterologica Belgica","volume":"87 3","pages":"424-426"},"PeriodicalIF":1.3,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142455742","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Regulatory, diagnostic, and therapeutic roles of microRNAs in chronic liver diseases. 微小核糖核酸在慢性肝病中的调节、诊断和治疗作用。

IF 1.3 4区医学

Acta gastro-enterologica Belgica Pub Date : 2024-07-01 DOI: 10.51821/87.2.12965

Razieh Kazemzadeh, Maryam Kheirollahi, Seyed Ali Mard, Akram Ahangarpour, Feryal Savari

{"title":"Regulatory, diagnostic, and therapeutic roles of microRNAs in chronic liver diseases.","authors":"Razieh Kazemzadeh, Maryam Kheirollahi, Seyed Ali Mard, Akram Ahangarpour, Feryal Savari","doi":"10.51821/87.2.12965","DOIUrl":"https://doi.org/10.51821/87.2.12965","url":null,"abstract":"Fibrogenesis is initially performed during tissue damage to protect the remaining tissues from the progressive death of epithelial cells, infiltration of immune and inflammatory cells, and local degrading enzymes. Inflammation can lead to excessive extracellular matrix deposition by fibroblasts and the induction of fibrosis in many organs, such as the liver. MiRNAs are small noncoding RNAs that mediate mRNA repression or destabilization, leading to translational repression. Owing to the wide range of roles of miRNAs in the development of fibrosis, especially liver fibrosis, many studies have focused on their diagnostic, regulatory, and therapeutic roles. In this study, we used medical science and general databases, including PubMed, Elsevier, Scopus, Nature, and Google Scholar, to find valid studies on the different roles of miRNAs in liver fibrosis. Because a large number of miRNAs with regulatory, diagnostic, and therapeutic roles in diseases associated with liver fibrosis have been identified and reported in this study, special attention to these elements is needed in the future of healthcare systems.","PeriodicalId":7322,"journal":{"name":"Acta gastro-enterologica Belgica","volume":"87 3","pages":"403-412"},"PeriodicalIF":1.3,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142455749","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Small bowel obstruction on food impaction after binge eating. 暴饮暴食后食物嵌塞导致小肠梗阻。

IF 1.3 4区医学

Acta gastro-enterologica Belgica Pub Date : 2024-07-01 DOI: 10.51821/87.3.12506

E Van Eecke, L Crapé, I Colle

引用次数: 0

An uncommon indication for liver transplantation: toxic epidermal necrolysis. 肝脏移植的罕见适应症：中毒性表皮坏死症。

IF 1.3 4区医学

Acta gastro-enterologica Belgica Pub Date : 2024-07-01 DOI: 10.51821/87.3.13045

B Uzakgider, D Kayar Calili, Y Genc, I Ozkocak Turan

引用次数: 0

Bile acid malabsorption investigated by selenium-75-homocholic acid taurine (75SeHCAT) scans, a retrospective single-centre experience. 通过硒-75-高胆酸牛磺酸（75SeHCAT）扫描检查胆汁酸吸收不良，这是一项回顾性单中心经验。

IF 1.3 4区医学

Acta gastro-enterologica Belgica Pub Date : 2024-07-01 DOI: 10.51821/87.3.13036

F Vulsteke, R De Gersem, J Arts, T Vanuytsel

{"title":"Bile acid malabsorption investigated by selenium-75-homocholic acid taurine (75SeHCAT) scans, a retrospective single-centre experience.","authors":"F Vulsteke, R De Gersem, J Arts, T Vanuytsel","doi":"10.51821/87.3.13036","DOIUrl":"https://doi.org/10.51821/87.3.13036","url":null,"abstract":"Background: Bile acid malabsorption (BAM) is a common entity in patients experiencing chronic watery diarrhea. However, literature suggests that BAM is underdiagnosed and undertreated. In many countries 75SeHCAT is the gold standard for diagnosing BAM (1-5). The aim of this retrospective study was to investigate the frequency of BAM using 75SeHCAT scintigraphy and the response to treatment with bile acid sequestrants.Methods: We retrospectively evaluated the clinical data of 420 patients who had a 75SeHCAT scan from January 2016 to January 2023. Electronic medical records were investigated for risk factors of BAM. BAM was defined as a 75SeHCAT retention of less than 15%. Response to bile acid sequestrants was evaluated based on outpatient clinical reports.Results: Median age at the time of 75SeHCAT test was 47 years (range 14-87). Out of 420 patients, 192 (46%) had a positive result for BAM. Cholecystectomy and ileal resection were significant predictors for BAM (p<0.001). BAM type 1 is statistically more likely to be more severe compared to type 2 (p<0.0001) and compared to type 3 (p=0.0021). In patients who fulfilled Rome IV criteria for IBS-D or functional diarrhea, 75 out of 121 (38%) tested positive for BAM. Overall, treatment with bile acid binders was effective in 76%.Conclusions: This retrospective study of patients who underwent SeHCAT scanning confirms that about 1/3 patients presenting with therapy-resistant chronic diarrhea in secondary care suffer from BAM. Including the test in clinical management protocols of chronic diarrhea allows early and quantitative diagnosis and treatment of BAM.","PeriodicalId":7322,"journal":{"name":"Acta gastro-enterologica Belgica","volume":"87 3","pages":"381-387"},"PeriodicalIF":1.3,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142455741","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Prevalence of metabolic dysfunction-associated fatty liver disease after pancreatic surgery in a historical Belgian cohort and review of the literature. 比利时历史群组中胰腺手术后代谢功能障碍相关脂肪肝的发病率及文献综述。

IF 1.3 4区医学

Acta gastro-enterologica Belgica Pub Date : 2024-07-01 DOI: 10.51821/87.3.10078

V D'Cruz, A De Zutter, M Van den Broecke, S Ribeiro, L Abreu de Carvalho, P Smeets, C Lecluyse, E Pape, E Callebout, F Berrevoet, K Geboes

{"title":"Prevalence of metabolic dysfunction-associated fatty liver disease after pancreatic surgery in a historical Belgian cohort and review of the literature.","authors":"V D'Cruz, A De Zutter, M Van den Broecke, S Ribeiro, L Abreu de Carvalho, P Smeets, C Lecluyse, E Pape, E Callebout, F Berrevoet, K Geboes","doi":"10.51821/87.3.10078","DOIUrl":"10.51821/87.3.10078","url":null,"abstract":"Background and objectives: Metabolic dysfunction-associated fatty liver disease (MAFLD) has been reported as a complication after pancreatic surgery. The aim of this study is to assess this phenomenon in a Belgian population, specifically in a period in time when less perioperative chemotherapy was given.Methods: We performed a retrospective monocentric cohort study with 124 selected patients who underwent pancreatic surgery - pancreaticoduodenectomy (PD), distal pancreatectomy (DP) or total pancreatectomy - between 2005 and 2014. Steatosis was assessed radiologically, using Hounsfield units on liver and spleen. Data on imaging, liver function, weight and other relevant parameters were gathered preoperatively as well as 2 and 6 months, 1 and 2 years after surgery.Results: Thirty-eight (31%) out of 124 patients developed liver steatosis at least at one point in time in the two years following surgery, with a prevalence of 21.0% at 2 months, 28.6% at 6 months, 16.4% at 1 year and 20.8 % at 2 years. A statistically significant association with preoperative AST and ALT values, administration of pancreatic enzyme supplementation as a surrogate for pancreatic exocrine insufficiency (PEI) and weight loss at 2 years was detected.Conclusion: MAFLD is seen in 31% of patients with PD or DP pancreatic resection in this retrospective analysis of a monocentric Belgian cohort. Both early and late onset of MAFLD was observed, implying that long-term follow-up is necessary. Clinical impact as well as a direct correlation with patients' weight and oral enzyme supplements needs to be further investigated.","PeriodicalId":7322,"journal":{"name":"Acta gastro-enterologica Belgica","volume":"87 3","pages":"373-380"},"PeriodicalIF":1.3,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142455748","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Investigation of the prevalence of functional constipation and its related factors for in older outpatients. 老年门诊患者功能性便秘发病率及其相关因素调查。

IF 1.3 4区医学

Acta gastro-enterologica Belgica Pub Date : 2024-07-01 DOI: 10.51821/87.3.12949

M Esra Bozkurt, T Erdogan, Z Fetullahoglu, S Ozkok, C Kilic, G Bahat, M Akif Karan

{"title":"Investigation of the prevalence of functional constipation and its related factors for in older outpatients.","authors":"M Esra Bozkurt, T Erdogan, Z Fetullahoglu, S Ozkok, C Kilic, G Bahat, M Akif Karan","doi":"10.51821/87.3.12949","DOIUrl":"https://doi.org/10.51821/87.3.12949","url":null,"abstract":"Background: Functional constipation (FC) is a geriatric syndrome that is common in the older adult's population and can seriously affect the quality of life and may be a frequent cause of hospital visits. In this study, we planned to investigate the relationship between FC and its related factors for in older outpatients.Patients and methods: Participants aged 65 and over who applied to the geriatrics outpatient were included in the study. The diagnosis of FC was made according to the presence of the Rome IV criteria. Frailty was screened by the using FRAIL scale, ≥ 3 a score of were evaluated as frail. Participants quality of life was evaluated by Euro-Quality of Life Visual Analog Scale (EQ-VAS).Results: The study included 602 participants. FC prevalence was found 28.7%. In univariate analyses, FC was found related to age, having a diagnosis of depression or Parkinson diseases, frailty, urinary incontinence, sleep disorders, number of chronic diseases, and EQ-VAS. In multivariate analyses, FC was not found to be associated by the frailty while the number of chronic diseases [OR=1.212, 95%CI (1.084-1.355), p=0.001] and EQ-VAS were found to be related [OR=0.988, 95%CI (0.978-0.997), p=0.012].Conclusion: In the results of this study, FC was not found to be associated by frailty in older outpatients but it emerged as a syndrome that should be screened frequently in patients with a high number of chronic diseases and a low general quality of life.","PeriodicalId":7322,"journal":{"name":"Acta gastro-enterologica Belgica","volume":"87 3","pages":"361-365"},"PeriodicalIF":1.3,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142455743","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

An unusual case of high gastrointestinal bleeding after Whipple surgery. 一例不寻常的 Whipple 手术后消化道大出血病例。

IF 1.3 4区医学

Acta gastro-enterologica Belgica Pub Date : 2024-07-01 DOI: 10.51821/87.3.12803

E Dubois, R Geelen

引用次数: 0

New onset inflammatory bowel disease after initiation of anti-IL-17a treatment: a case series. 抗IL-17a治疗后新发炎症性肠病：一个病例系列。

IF 1.3 4区医学

Acta gastro-enterologica Belgica Pub Date : 2024-07-01 DOI: 10.51821/87.3.12874

J Geldof, M Truyens, B Strubbe, S Claeys, G Dewitte, E Glorieus, A Hoorens, T Lobaton

引用次数: 0