Health sciences review (Oxford, England)最新文献_第7页

Unveiling the therapeutic potential of butein: A comprehensive review 揭示丁素的治疗潜力：全面综述

Health sciences review (Oxford, England) Pub Date : 2024-12-01 Epub Date: 2024-09-04 DOI: 10.1016/j.hsr.2024.100197

Pougang Golmei, Sweta Kasna, Sachin Kumar

{"title":"Unveiling the therapeutic potential of butein: A comprehensive review","authors":"Pougang Golmei, Sweta Kasna, Sachin Kumar","doi":"10.1016/j.hsr.2024.100197","DOIUrl":"10.1016/j.hsr.2024.100197","url":null,"abstract":"<div><p>This exhaustive review examines the therapeutic possibilities of butein, an organic compound sourced from plants, which has a long history in traditional medicine. Initiating with an investigation of plant-based remedies in native societies, the review emphasizes the importance of researching the physiological effects of plant-derived chemicals. The multifaceted biological activities of butein, encompassing its anti-inflammatory, antioxidant, anti-cancer, and neuroprotective properties are systematically analyzed. Detailed discussions elucidate the underlying mechanisms driving these activities and the wide-ranging applications of butein in managing various illnesses such as cancer, neurodegenerative disorders, and cardiovascular ailments. The article also explores the challenges associated with developing butein as a therapeutic agent, including issues with bioavailability and toxicity. The authors deliberate on diverse approaches to surmount these obstacles, incorporating the application of innovative drug delivery systems and the synthesis of artificial analogs. On the whole, this review offers a thorough outline of the therapeutic potential of butein and underscores the significance of investigating plant-based compounds for the formulation of novel medications. It is deduced that butein holds substantial promise as a therapeutic remedy, necessitating further exploration to fully comprehend its mechanisms of operation and potential applications in clinical environments.</p></div>","PeriodicalId":73214,"journal":{"name":"Health sciences review (Oxford, England)","volume":"13 ","pages":"Article 100197"},"PeriodicalIF":0.0,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2772632024000503/pdfft?md5=9b3960f2d13a8b570acd42c1a6bfc0d4&pid=1-s2.0-S2772632024000503-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142164935","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Revolutionizing menopause management: Nonhormonal therapy for vasomotor symptoms 更年期管理的革命：治疗血管运动症状的非激素疗法

Health sciences review (Oxford, England) Pub Date : 2024-12-01 Epub Date: 2024-09-18 DOI: 10.1016/j.hsr.2024.100200

Shanzey Rai , Natalia Aslam Khan

引用次数: 0

Harnessing the power of natural products against bacterial urinary tract infections: A perspective review for cultivating solutions 利用天然产品的力量对抗细菌性尿路感染：培养解决方案的视角回顾

Health sciences review (Oxford, England) Pub Date : 2024-12-01 Epub Date: 2024-09-11 DOI: 10.1016/j.hsr.2024.100199

Rahima Tanbin Tama , Md. Sakhawat Hossain , Md. Ashikur Rahaman , Md. Ashraful Alam , Md-Mafizur Rahman , Anzana Parvin , Rifaia Sultana Chowdhury , Md. Shahidul Islam

{"title":"Harnessing the power of natural products against bacterial urinary tract infections: A perspective review for cultivating solutions","authors":"Rahima Tanbin Tama , Md. Sakhawat Hossain , Md. Ashikur Rahaman , Md. Ashraful Alam , Md-Mafizur Rahman , Anzana Parvin , Rifaia Sultana Chowdhury , Md. Shahidul Islam","doi":"10.1016/j.hsr.2024.100199","DOIUrl":"10.1016/j.hsr.2024.100199","url":null,"abstract":"<div><p>Urinary tract infection (UTI) is a prevalent and recurrent bacterial infection affecting millions of people across the world, often necessitating antibiotic treatment. However, the rise of multidrug-resistant (MDR) strains, commonly known as \"superbugs,\" has complicated the treatment process. This perspective review summarized the mechanisms of herbal or natural therapeutics intervention in UTI from the perspective of UTI bacterial pathogenesis. Initially, the review explores the mechanism of UTI development, identifying the types of UTI-causing bacteria, the complexity of UTI infection, and the human host's immune system against UTI. Then, this review synthesizes the active compounds of natural therapeutics for UTI, exploring their active compounds, efficacy, and mechanisms of action. After that, we summarized the emerging research on herbal compound interventions in UTI and analyzed the literature in this regard, including clinical applications, suggestions for potential natural bioactive compound consumption with the aim of UTI complications, as well as the association between novel mechanisms of UTI remission with the potential for active natural compounds intervention. Finally, we noted key future recommendations for using natural therapeutics. In conclusion, this review sheds light on the potential role of herbal or natural compounds in UTI treatment, from proposed mechanisms to prospects, offering a promising alternative or complement to conventional therapies in relieving UTIs.</p></div>","PeriodicalId":73214,"journal":{"name":"Health sciences review (Oxford, England)","volume":"13 ","pages":"Article 100199"},"PeriodicalIF":0.0,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2772632024000527/pdfft?md5=97985aa6af8e26f4cd9178c95c273045&pid=1-s2.0-S2772632024000527-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142232142","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Incidence and risk factors associated with human mastitis 人类乳腺炎的发病率和相关风险因素

Health sciences review (Oxford, England) Pub Date : 2024-09-01 Epub Date: 2024-07-05 DOI: 10.1016/j.hsr.2024.100191

Pratiksha Gondkar, Hemant Kumar, Khushal Patel

{"title":"Incidence and risk factors associated with human mastitis","authors":"Pratiksha Gondkar, Hemant Kumar, Khushal Patel","doi":"10.1016/j.hsr.2024.100191","DOIUrl":"https://doi.org/10.1016/j.hsr.2024.100191","url":null,"abstract":"<div><p>Human mastitis is an infection that affects the mammary glands of females and mainly occurs during the puerperium, a common condition brought on by improper breastfeeding technique. Mastitis is differentiated into lactational and non-lactational types according to its symptoms. Based on the available data, the pooled incidence of mastitis across countries like the USA, UK, Australia, Denmark, Turkey, Finland and New Zealand is estimated to be 13.45%. Poor hygiene, sore and cracked nipples, nipple piercing, smoking and fitted innerwear are reported risk factors. <em>Staphylococcus aureus</em> and <em>Staphylococcus epidermidis</em> are predominant pathogens, with a prevalence range between 50 to 87%, respectively. Mastitis management is essential to reduce infection rates and discover alternate treatments. Studies indicate that antibiotic treatment may be substituted for herbal and probiotic therapies. In addition, if mastitis is not adequately diagnosed in females, there is a high risk of breast cancer. Mastitis is a significant health issue, but it is often overlooked in the field of human medicine. In this review, we have focused on the risk factors, the alternative therapeutic approaches, and the relationship of breast cancer associated with mastitis.</p></div>","PeriodicalId":73214,"journal":{"name":"Health sciences review (Oxford, England)","volume":"12 ","pages":"Article 100191"},"PeriodicalIF":0.0,"publicationDate":"2024-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2772632024000448/pdfft?md5=269a87681bfce596d02d2db52dc997b3&pid=1-s2.0-S2772632024000448-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141582960","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Trim the fat, trim the risk: Can bariatric surgery prevent breast cancer? "减少脂肪，降低风险：减肥手术能预防乳腺癌吗？

Health sciences review (Oxford, England) Pub Date : 2024-09-01 Epub Date: 2024-06-15 DOI: 10.1016/j.hsr.2024.100184

Asad Gul Rao, Neha Pervez

引用次数: 0

Challenges and opportunities in precision therapy for diabetic patients 糖尿病患者精准治疗的挑战与机遇

Health sciences review (Oxford, England) Pub Date : 2024-09-01 Epub Date: 2024-07-02 DOI: 10.1016/j.hsr.2024.100190

Ruchika Sharma , Pankaj Musyuni , Jaseela Majeed , Geeta Aggarwal

{"title":"Challenges and opportunities in precision therapy for diabetic patients","authors":"Ruchika Sharma , Pankaj Musyuni , Jaseela Majeed , Geeta Aggarwal","doi":"10.1016/j.hsr.2024.100190","DOIUrl":"10.1016/j.hsr.2024.100190","url":null,"abstract":"<div><p>Diabetes, a chronic condition characterized by an inability to maintain normal glucose levels significantly accounts for enhancing the cost of healthcare expenditure. Managing diabetes using a standard medication protocol more often leads to progressive failure in effectively treating the associated complications. The recent trends involve understanding of diabetes's genetic architecture and its consequences have provided the background for application of precision medicine for customizing protocols for preventing and managing the diabetes therapy. Further, utilizing the electronic health data and genetic information for assisting care and planning therapeutic protocol for monogenic form of diabetes is well-executed example of genomic medicine. The present write-up emphasized recent advances about the causes and effects of diabetes genetics. This also drive to the need for the further investigation for ensuring the appropriate knowledge to enable patients and healthcare providers to make informed decisions for obtaining the best possible outcome.</p></div>","PeriodicalId":73214,"journal":{"name":"Health sciences review (Oxford, England)","volume":"12 ","pages":"Article 100190"},"PeriodicalIF":0.0,"publicationDate":"2024-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2772632024000436/pdfft?md5=91c275318bee0cf82e54dd8d44d869cd&pid=1-s2.0-S2772632024000436-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141638288","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Sertraline: A potential drug of choice for post-myocardial infarction depression in South Asia 舍曲林：南亚地区心肌梗死后抑郁症的潜在首选药物

Health sciences review (Oxford, England) Pub Date : 2024-09-01 Epub Date: 2024-07-05 DOI: 10.1016/j.hsr.2024.100193

Muhammad Shaheer Bin Faheem , Hafiz Muhammad Kamran Ahmed Mughal , Kanza Zahid , Omer Farooq , Muhammad Ibraiz Bilal , Danish Ali Ashraf

引用次数: 0

Advancements in ulcerative colitis management: A critical assessment of etrasimod therapy 溃疡性结肠炎治疗的进展：对依曲莫德疗法的重要评估

Health sciences review (Oxford, England) Pub Date : 2024-09-01 Epub Date: 2024-08-11 DOI: 10.1016/j.hsr.2024.100196

Kushal Seni , Aniket Saini , Rabin Debnath , Arshdeep Singh , Anjali Sharma , Deepak Singh Bisht , Viney Chawla , Pooja A Chawla

{"title":"Advancements in ulcerative colitis management: A critical assessment of etrasimod therapy","authors":"Kushal Seni , Aniket Saini , Rabin Debnath , Arshdeep Singh , Anjali Sharma , Deepak Singh Bisht , Viney Chawla , Pooja A Chawla","doi":"10.1016/j.hsr.2024.100196","DOIUrl":"10.1016/j.hsr.2024.100196","url":null,"abstract":"<div><p>Ulcerative Colitis (UC) is a persistent inflammatory condition of the colon that occurs due to the disruption in the epithelial barrier and immunological responses. In UC the episodes of inflammation are relapsing and remitting in the colonic mucosa. Etrasimod, an S1P receptor modulator, is a potential therapy for UC. The goal of this review is to compile the data related to effectiveness and safety studies of etrasimod in the treatment of UC. Pre-clinical and clinical studies examine how etrasimod affects many aspects of UC pathophysiology, including S1P receptor regulation, immune cell migration, and improved gut barrier function. Etrasimod mainly inhibits the lymphocytes entry into the peripheral blood and prevents the migration of lymphocytes into the inflammation cycle. This article gives a comprehensive account of several factors linked to etrasimod and ulcerative colitis, including the pathology of ulcerative colitis, US-FDA approved treatment for UC, mechanism of action of etrasimod, pharmacokinetic, pharmacodynamic data of etrasimod, reported risk and related aspects and completed and ongoing clinical trials.</p></div>","PeriodicalId":73214,"journal":{"name":"Health sciences review (Oxford, England)","volume":"12 ","pages":"Article 100196"},"PeriodicalIF":0.0,"publicationDate":"2024-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2772632024000497/pdfft?md5=4a3196e7ca54c973b37354acd69e2153&pid=1-s2.0-S2772632024000497-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142002102","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Transforming pediatric speech and language disorder diagnosis and therapy: The evolving role of artificial intelligence 改变儿科言语和语言障碍的诊断与治疗：人工智能不断发展的作用

Health sciences review (Oxford, England) Pub Date : 2024-09-01 Epub Date: 2024-06-24 DOI: 10.1016/j.hsr.2024.100188

Ankur Bhardwaj , Mridul Sharma , Sahil Kumar , Sumit Sharma , Prabodh Chander Sharma

{"title":"Transforming pediatric speech and language disorder diagnosis and therapy: The evolving role of artificial intelligence","authors":"Ankur Bhardwaj , Mridul Sharma , Sahil Kumar , Sumit Sharma , Prabodh Chander Sharma","doi":"10.1016/j.hsr.2024.100188","DOIUrl":"https://doi.org/10.1016/j.hsr.2024.100188","url":null,"abstract":"<div><p>Integrating artificial intelligence (AI) with healthcare offers a viable way to treat difficult issues like children's speech-sound disorder (SSD).AAC, or augmentative alternative communication, has shown great promise in helping people with SSD, and AI-driven methods hold even more promise for improving diagnosis and therapy. This review paper explores the synergy of AI, ML, and AAC in pediatric speech and language impairments. It also highlights current developments and potential future directions. Healthcare providers can improve communication outcomes for kids with speech impairments, increase early detection, and provide personalised therapy by utilizing AI and ML techniques. In addition to encouraging parental involvement, the combination of AI and AAC technologies spurs advancements in speech therapy applications. AI has the potential to transform healthcare and improve the quality of life for people with speech and language problems as it develops and works in tandem with medical knowledge.</p></div>","PeriodicalId":73214,"journal":{"name":"Health sciences review (Oxford, England)","volume":"12 ","pages":"Article 100188"},"PeriodicalIF":0.0,"publicationDate":"2024-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2772632024000412/pdfft?md5=c864e0a389ace1998e31ba275221792d&pid=1-s2.0-S2772632024000412-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141582961","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Is it time to define vaccines to be used for lumpy skin disease? 是时候确定用于治疗块状皮肤病的疫苗了吗？

Health sciences review (Oxford, England) Pub Date : 2024-09-01 Epub Date: 2024-07-08 DOI: 10.1016/j.hsr.2024.100192

Krishna Prasad Acharya , Bhoj Raj Singh

引用次数: 0