{"title":"The impact of COVID-19 pandemic in high-burden countries for tuberculosis: A systematic review","authors":"Swapna Ponnampalli , Naga Venkata Suryanarayana Birudukota","doi":"10.1016/j.hsr.2023.100128","DOIUrl":"https://doi.org/10.1016/j.hsr.2023.100128","url":null,"abstract":"<div><h3>Purpose</h3><p>Tuberculosis (TB) and coronavirus disease 2019 (COVID-19) are the two most significant health challenges faced by the public. Numerous confirmed COVID-19 cases worldwide are concentrated in nations already burdened with TB. The COVID-19 pandemic has surpassed all other health issues globally and has significantly impacted the prevalence of TB.</p></div><div><h3>Methods</h3><p>A PubMed literature search (2020–2022) using the keywords, “Tuberculosis”, “Drug-resistant Tuberculosis”, “Impact of the Pandemic”, “SARS-CoV2” “COVID-19″ and “Public health”, was performed. Additional statistical information has been gathered from online databases such as the WHO COVID-19 dashboard, Nikshay Portal, and Worldometer, India.</p></div><div><h3>Results</h3><p>India, Indonesia, and the Philippines were the major contributors to the steep fall in global TB case notifications. Being the highest TB burden country, detailed trends were observed in monthly TB reports in India, compared with the newly confirmed COVID-19 cases. Flow diagrams of TB studies along with COVID-19 reports have been included in the review.</p></div><div><h3>Discussion</h3><p>A remarkable strain in the TB control programs was seen in high-TB troubled countries during the COVID-19 pandemic, in comparison to pre-pandemic and post-pandemic. A possible key to the prevention of the burden of TB lies in dealing with its risk factors; simultaneously raising the funds and sustaining investment in healthcare systems to address the needs of the poor and robust to the threat of epidemics. These countries should have a perpetual TB strategy to reach the target by 2030, together with an effective strategy for COVID-19 management.</p></div>","PeriodicalId":73214,"journal":{"name":"Health sciences review (Oxford, England)","volume":"9 ","pages":"Article 100128"},"PeriodicalIF":0.0,"publicationDate":"2023-10-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49811385","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Lucy H. Ablett , Heather Hopper , Stephanie Maslin
{"title":"How to promote exclusive breastfeeding with antenatal milk expression and implementation science: A mixed methods systematic review","authors":"Lucy H. Ablett , Heather Hopper , Stephanie Maslin","doi":"10.1016/j.hsr.2023.100124","DOIUrl":"https://doi.org/10.1016/j.hsr.2023.100124","url":null,"abstract":"<div><h3>Background</h3><p>Only 48 % of infants worldwide achieve the World Health Organization's recommendation of exclusive breastfeeding for the first six months of life. The leading cause of early breastfeeding cessation is self-reported milk insufficiency. Research into breastfeeding interventions that focus on promoting a person's confidence in their milk supply is therefore recommended.</p></div><div><h3>Purpose</h3><p>This systematic review aimed to explore whether antenatal milk expression could be optimized as a breastfeeding promotion intervention, using implementation science.</p></div><div><h3>Methods</h3><p>The Joanna Briggs Institute convergent segregated approach to mixed methods systematic reviews was used. A meta-aggregation and CERQual assessment of qualitative data was undertaken. Effect estimates of relevant quantitative data were summarized in forest plots. Results were organized into the following five implementation outcomes from an evidence-based framework: acceptability, appropriateness, adoption, feasibility, and fidelity.</p></div><div><h3>Results</h3><p>Of the 207 studies identified, 22 were included. A significant proportion of people will find the intervention acceptable, but those who do not will require additional ongoing support. Among people with diabetes, antenatal milk expression is associated with greater exclusive breastfeeding rates up to three months postpartum. Qualitative data described how antenatal milk expression may physically and psychologically prepare people for breastfeeding, encourage resilience, reassure individuals of their ability to produce milk and lead to a volume of stored colostrum.</p></div><div><h3>Conclusions</h3><p>There is evidence that antenatal milk expression may prevent early breastfeeding cessation among people with diabetes. Further quantitative research is needed to confirm the efficacy of antenatal milk expression for other groups. Optimal implementation requires training for relevant healthcare professionals, alongside education and ongoing support for the pregnant population.</p></div>","PeriodicalId":73214,"journal":{"name":"Health sciences review (Oxford, England)","volume":"9 ","pages":"Article 100124"},"PeriodicalIF":0.0,"publicationDate":"2023-10-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49811373","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Community-based interventions to prevent stroke in low and middle-income countries: A systematic review","authors":"Iffat Nowrin , Jeenat Mehareen , Dipika Shankar Bhattacharyya , KM Saif-Ur-Rahman","doi":"10.1016/j.hsr.2023.100123","DOIUrl":"https://doi.org/10.1016/j.hsr.2023.100123","url":null,"abstract":"<div><p>We aimed to identify community-based interventions to prevent stroke in low-and-middle-income countries. A comprehensive search in Medline through PubMed, Web of Science (core collection), and Scopus was conducted in October, 2021 and updated in August, 2023. Studies published only in English between 1st January, 2000 and August 26, 2023 were included in the review. The screening and data extraction were performed by two reviewers independently. Two authors independently evaluated the included papers' Risk of Bias; we utilized the Cochrane ROB (Risk of Bias) tool for randomized controlled trials (RCT) and non-randomized studies were assessed using ROBANS (Risk of Bias Assessment tool for non-randomized studies). Meta-analysis was not conducted due to the heterogeneity of the included studies in terms of methods and outcomes. A narrative synthesis was performed to report the results. This systematic review was registered in PROSPERO (International prospective register of systematic reviews) – CRD 42021283670. A total of six studies were included in the review. Most of the studies highlighted community-based educational intervention to improve knowledge regarding stroke, it's signs, and risk factors. An important component of community-based intervention found in the review was involving community health professionals in educating the local population about health. Educational interventions were found effective in reducing stroke risk factors such as blood pressure, and cholesterol level. To lessen the enormous burden of stroke, effective community-based programs for prevention can be expanded and incorporated into resource-poor health systems.</p></div>","PeriodicalId":73214,"journal":{"name":"Health sciences review (Oxford, England)","volume":"9 ","pages":"Article 100123"},"PeriodicalIF":0.0,"publicationDate":"2023-09-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49811379","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Emerging the Role of Mercury in Stroke: A Mini Review","authors":"Kamaljeet, Amit Sharma","doi":"10.1016/j.hsr.2023.100122","DOIUrl":"https://doi.org/10.1016/j.hsr.2023.100122","url":null,"abstract":"<div><p>The impact of long-term exposure to several heavy metals in the environment on general health is causing growing concern. Mercury in particular falls into this category but other heavy metals are less prevalent. Among all heavy metals, mercury is the most toxic. Oxidative stress and dysfunctional mitochondria are brought on by mercury. This causes the inner mitochondrial membrane to depolarize, auto-oxidize, and undergo severe lipid peroxidation and mitochondrial malfunction. Mercury enhances lipid peroxidation, LDL oxidation, and plasma oxLDL complexes while inhibiting glutathione, catalase, and superoxide dismutase. Chronic mercury exposure (even at very low levels), increases inflammation, oxidative stress, oxidative defense, and nitric oxide bioavailability and stimulates endothelial dysfunction, which increases the risk of CVD and CVA. In the future, more investigations and studies are needed to prevent the patients from mercury toxicity which leads to stroke and other illness.</p></div>","PeriodicalId":73214,"journal":{"name":"Health sciences review (Oxford, England)","volume":"9 ","pages":"Article 100122"},"PeriodicalIF":0.0,"publicationDate":"2023-09-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49811434","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Engineering liquid metal-based implantable electrodes toward brain-machine interfaces","authors":"Xia Qian , Caizhi Liao","doi":"10.1016/j.hsr.2023.100118","DOIUrl":"https://doi.org/10.1016/j.hsr.2023.100118","url":null,"abstract":"<div><p>Driven by the development of innovative electrode materials, the brain-machine interface (BMI) has witnessed significant advancements in recent years. However, traditional implantable electrodes, such as metal-based and polymer-based electrodes, often face limitations in terms of flexibility, chronic stability, and long-term biocompatibility. Liquid metal-based electrodes have emerged as a promising alternative to traditional electrode materials, offering unique properties and numerous advantages for BMI applications. In this Review, we provided an in-depth overview of liquid metal-based electrodes. Liquid metal-based electrodes demonstrate several desirable features, including high electrical conductivity, flexibility, biocompatibility, and the ability to conform to the irregular and delicate structures of the brain. We also systematically and thematically discussed their material properties, biocompatibility considerations, performance characteristics, and assorted applications in neural recording, stimulation, brain-machine interfaces, closed-loop feedback systems, and neuroprosthetics. Meanwhile, long-term stability, biocompatibility, electrode-tissue interface, miniaturization, signal processing, and ethical considerations are areas that require further research and innovation. Addressing these challenges will contribute to the successful integration and widespread use of liquid metal-based electrodes in BMI systems.</p></div>","PeriodicalId":73214,"journal":{"name":"Health sciences review (Oxford, England)","volume":"9 ","pages":"Article 100118"},"PeriodicalIF":0.0,"publicationDate":"2023-09-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49811435","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Amit Bhandari , Prakash Raj Oli , Dhan Bahadur Shrestha , Sagun Dawadi , Bishnu Deep Pathak , Manoj Bhandari , Yub Raj Sedhai , Bibhusan Basnet , Laxmi Regmi , Aniruddha Singh , Nimesh K. Patel
{"title":"Clinical efficacy and safety outcomes of bempedoic acid: An updated systematic review and meta-analysis after CLEAR Outcomes trial","authors":"Amit Bhandari , Prakash Raj Oli , Dhan Bahadur Shrestha , Sagun Dawadi , Bishnu Deep Pathak , Manoj Bhandari , Yub Raj Sedhai , Bibhusan Basnet , Laxmi Regmi , Aniruddha Singh , Nimesh K. Patel","doi":"10.1016/j.hsr.2023.100116","DOIUrl":"https://doi.org/10.1016/j.hsr.2023.100116","url":null,"abstract":"<div><h3>Purpose</h3><p>Statins are the cornerstone therapy for primary or secondary prevention of atherosclerotic cardiovascular disease (ASCVD). However, a significant portion of patients are intolerant to statin or show inadequate lipid-lowering. Bempedoic acid (BA) has been shown to decrease low-density lipoprotein cholesterol (LDL-C) in clinical trials. However, the evidence on the effect of BA on clinical cardiovascular outcomes was limited until the CLEAR Outcomes trial. Thus, to fully appraise the available data, we performed this meta-analysis.</p></div><div><h3>Methods</h3><p>PubMed, Pubmed Central, Embase, and Scopus databases were searched for relevant articles published before May 1, 2023. Pertinent data from the included studies were extracted and analyzed using RevMan v5.4.</p></div><div><h3>Results</h3><p>Out of 2209 studies evaluated, five randomized control trials with 17,384 patients with established ASCVD or at high risk of ASCVD were included for analysis. The BA therapy reduced major adverse cardiovascular events (OR 0.85, CI 0.77-0.93; <0.0001), non-fatal myocardial infarction (OR 0.75, 95 % CI 0.64-0.88; <em>p <</em>0.0001), hospitalization for unstable angina (OR 0.69, CI 0.53-0.89; <em>p</em> = 0.005) and coronary revascularization (OR 0.80, CI 0.61-0.91; <0.0001) significantly without decreasing the risk of all-cause death (OR 1.19, CI 0.73-1.94; <em>p</em> = 0.49), cardiovascular death (OR 1.04, CI 0.87-1.25; <em>p</em> = 0.68) and non-fatal stroke (OR 0.84, CI 0.66-1.06; <em>p</em> = 0.15).</p></div><div><h3>Conclusion</h3><p>Based on our analysis the bempedoic acid addition to therapy reduced cardiovascular events in selective patients who are either intolerant to statins or do not achieve recommended LDL-C levels despite being on a maximum dose of statins and/or ezetimibe.</p></div>","PeriodicalId":73214,"journal":{"name":"Health sciences review (Oxford, England)","volume":"9 ","pages":"Article 100116"},"PeriodicalIF":0.0,"publicationDate":"2023-09-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49891729","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"An update on breast cancer chemotherapy-associated toxicity and their management approaches","authors":"Urvashi Langeh , Vishal Kumar , Palak Ahuja , Charan Singh , Arti Singh","doi":"10.1016/j.hsr.2023.100119","DOIUrl":"https://doi.org/10.1016/j.hsr.2023.100119","url":null,"abstract":"<div><p>As the incidence rate of breast cancer is increasing at an alarming rate these days, this is leading to an increase in the use of chemotherapy drugs. Here we used a systematic review to identify studies that reported adverse events related to chemotherapy and its management. We searched PubMed Central, Cochrane Library, Research Gate, Sci-Hub, and Web of Knowledge for relevant references. We included data from 1978 to 2021 in our analysis. Additionally, in this review, we have attempted to elucidate how cancer chemotherapy has affected the mind and body of the cancer survivor. We also provided insight into the adjuvant therapies that enable survivors to lead quality lives. Due to incomplete knowledge and sometimes fear of adverse effects, patients are reluctant to undergo cancer treatment. Combining cancer drugs with those that overcome associated side effects is a promising area for better patient outcomes.</p></div>","PeriodicalId":73214,"journal":{"name":"Health sciences review (Oxford, England)","volume":"9 ","pages":"Article 100119"},"PeriodicalIF":0.0,"publicationDate":"2023-09-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49811433","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Unravelling general practitioners' barriers to deal with long COVID: Experiences from Malta","authors":"Sarah Cuschieri , Sarah Moreels","doi":"10.1016/j.hsr.2023.100121","DOIUrl":"https://doi.org/10.1016/j.hsr.2023.100121","url":null,"abstract":"","PeriodicalId":73214,"journal":{"name":"Health sciences review (Oxford, England)","volume":"9 ","pages":"Article 100121"},"PeriodicalIF":0.0,"publicationDate":"2023-09-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49811437","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Anette Kaagaard Kristensen , Martin Lund Kristensen , Eva Gemzøe Mikkelsen
{"title":"Workplace hazing in nursing: An integrative literature review","authors":"Anette Kaagaard Kristensen , Martin Lund Kristensen , Eva Gemzøe Mikkelsen","doi":"10.1016/j.hsr.2023.100120","DOIUrl":"https://doi.org/10.1016/j.hsr.2023.100120","url":null,"abstract":"<div><p>This study aims to provide an integrative literature review of what characterizes the antecedents, experiences, and outcomes of nursing students’ and nurses’ workplace hazing experiences. The review combines theoretical and empirical studies of workplace hazing, nursing students, and newly graduated nurses’ transition experiences. An electronic database search was performed in CINAHL, Google Scholar, MEDLINE, ProQuest, PsycINFO, PUBMED, Scopus, and Web of Science. Fifty-five papers collecting data from 8,131 respondents (1,733 nursing students and 80 newly graduated nurses) published from 1968 to 2023 and reporting on research occurring in a non-virtual workplace setting, were synthesized and analyzed using thematic coding. The study found that nursing students and new nurses are typically exposed to segregation and person- and work-based workplace hazing by their experienced colleagues during the transition, adversely affecting their physical, emotional, and psychological well-being and relational quality expectations. Applying the workplace hazing perspective to the nursing literature on newcomers’ transition experiences contributes to a nuanced understanding of the phenomenon and its underlying motivation and illuminates its ambiguous moral character. Furthermore, despite prioritizing the group's welfare above that of the newcomer, hazing's adverse individual outcomes might ultimately damage the workgroup and organization and contribute to a further nursing shortage.</p></div>","PeriodicalId":73214,"journal":{"name":"Health sciences review (Oxford, England)","volume":"9 ","pages":"Article 100120"},"PeriodicalIF":0.0,"publicationDate":"2023-09-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49811374","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}