Leveraging spray drying technique for advancing biologic product development–A mini review

Mahipal Reddy Donthi , Arun Butreddy , Ranendra Narayan Saha , Prashant Kesharwani , Sunil Kumar Dubey
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引用次数: 0

Abstract

Over the last 15 years, spray drying (SD), as an alternative to lyophilization, to manufacture and increase the stability of biologics has demonstrated promising outcomes. Pharmaceutical companies, on the other hand, have yet to expand technology for the production of aseptic spray-dried biologics. In this mini-review, we have discussed the limitations and potential of SD in biologics production.

利用喷雾干燥技术推进生物产品开发--微型综述
在过去的 15 年中,喷雾干燥(SD)作为冻干的一种替代方法,在生产生物制剂并提高其稳定性方面取得了可喜的成果。而另一方面,制药公司尚未扩展无菌喷雾干燥生物制剂的生产技术。在这篇微型综述中,我们讨论了无菌喷雾干燥技术在生物制剂生产中的局限性和潜力。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
Health sciences review (Oxford, England)
Health sciences review (Oxford, England) Medicine and Dentistry (General)
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