Health sciences review (Oxford, England)最新文献

{"title":"Strategies for implementation of patient and family-centered care in the perioperative context: A scoping review","authors":"Bernard Atinyagrika Adugbire, Portia Janine Jordan, Cornelle Young, Chinwe Iwu-Jaja","doi":"10.1016/j.hsr.2025.100220","DOIUrl":"10.1016/j.hsr.2025.100220","url":null,"abstract":"","PeriodicalId":73214,"journal":{"name":"Health sciences review (Oxford, England)","volume":"14 ","pages":"Article 100220"},"PeriodicalIF":0.0,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143403049","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Emotion-Induced Memory Distortions: Insights from Deese-Roediger-McDermott and Misinformation Paradigms—A Comprehensive Review","authors":"Gunjan Joshi ,&nbsp;Tanisha Rathore ,&nbsp;Kedarmal Verma","doi":"10.1016/j.hsr.2025.100216","DOIUrl":"10.1016/j.hsr.2025.100216","url":null,"abstract":"<div><div>This paper provides a comprehensive review of academic research pertaining to the interaction of emotions and false memory, elucidating the malleable nature of human memories. False memories can have serious effects in forensic and clinical settings, like misremembering events or making up events. In these contexts, the influence of emotions and misinformation can frequently lead to distortions in memory. The presence of intense emotional experiences within these environments, combined with the presence of multiple sources of deceptive information, increases the likelihood of the formation of false memories induced by suggestion. Clinically, understanding these dynamics is crucial for developing therapeutic interventions to mitigate the impact of false memories on individuals' mental health. This review paper delves into the intricate relationship between emotions and false memory, examining two primary paradigms: the Deese-Roediger-McDermott (DRM) and misinformation paradigms. The paper comprehensively synthesizes existing research, revealing that emotions significantly influence the generation and retrieval of false memories. Findings indicate that mood states and emotional content play pivotal roles in shaping memory distortions. In the DRM paradigm, negative mood tends to reduce false memory formation, while positive mood can amplify it. Emotional valence also impacts false recollections, with negative content often associated with increased false memories. In the misinformation paradigm, mood is impacting the confidence attributed to false recollections rather than affecting susceptibility to misinformation. When comparing emotional content, negative events are leading to induce more false memories due to their ease of recalling negative gist and semantic connections. Both the DRM and misinformation paradigms offer valuable insights into the underlying mechanisms of emotional false memory. The paper discusses the implications of these findings for various fields, such as forensic psychology and clinical settings, and highlights the need for further research to elucidate the complex interplay between emotions and memory.</div></div>","PeriodicalId":73214,"journal":{"name":"Health sciences review (Oxford, England)","volume":"14 ","pages":"Article 100216"},"PeriodicalIF":0.0,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143156603","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Network pharmacology and in silico investigation into the therapeutic potential of phytoconstituents of Peucedanum ostruthium as anti-tubercular agents","authors":"Neeru Bhanwala ,&nbsp;Raunak Katiyar ,&nbsp;Sumit Kumar ,&nbsp;Ashok K. Datusalia ,&nbsp;Gopal L. Khatik","doi":"10.1016/j.hsr.2025.100219","DOIUrl":"10.1016/j.hsr.2025.100219","url":null,"abstract":"<div><div><em>Mycobacterium tuberculosis</em> is the causative agent of tuberculosis (TB) globally. Despite significant progress in biomedical research, novel treatment strategies, and preventative measures, the incidence rates of TB continue to rise. <em>Peucedanum ostruthium</em>, often called <em>masterwort</em>, is a flowering plant from the <em>Apiaceae</em> family used to treat various ailments. However, the specific biochemical mechanism behind its therapeutic effect remains unidentified. The phytoconstituents of <em>P. ostruthium</em> were studied using Swiss Target Prediction to determine the target genes. The DisGeNET datasets were used to extract genes and variations associated with TB. Gene-gene interactions were examined using the STRING database, while gene enrichment analysis was done using the SR Plot database. <em>P. ostruthium</em> identified nine active constituents that have 256 potential therapeutic targets. In addition, the docking studies demonstrated that kampeferol-3-O-rutinoside exhibits stronger binding affinities to the Mycobacterial membrane protein Large 3 (MmpL3). This study presents compelling evidence that <em>P. ostruthium</em> may be effectively used to target TB after experimental validation. Additionally, it establishes a novel basis for additional experimental investigations into the anti-tubercular properties of <em>P. ostruthium</em>.</div></div>","PeriodicalId":73214,"journal":{"name":"Health sciences review (Oxford, England)","volume":"14 ","pages":"Article 100219"},"PeriodicalIF":0.0,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143360677","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Melasma management: Unveiling recent breakthroughs through literature analysis","authors":"Darshan Kumar R,&nbsp;Richa Sood,&nbsp;Prashant Tiwari","doi":"10.1016/j.hsr.2025.100213","DOIUrl":"10.1016/j.hsr.2025.100213","url":null,"abstract":"<div><div>Melasma is a prevalent acquired hyperpigmentation disorder characterized by irregular brownish patches on areas of the skin frequently exposed to sunlight. Although benign, it can significantly affect an individual's quality of life due to limited treatment options. Over the years, various therapeutic approaches, including topical agents, chemical peels, laser treatments, and oral medications, have been explored. However, managing melasma remains challenging, with high recurrence rates and inconsistent therapeutic outcomes. This review focuses on recent methodological advancements in elucidating the pathophysiology of melasma and the development of novel treatment strategies. Research leveraging histological analyses, genetic profiling, and biochemical assays has elucidated novel therapeutic targets, including oxidative stress pathways and inflammatory mediators. Advances in topical formulations, such as combination therapies containing tyrosinase inhibitors, antioxidants, and anti-inflammatory agents, have shown promising results in improving pigmentation and preventing recurrence. Furthermore, targeted delivery systems, such as nanoparticles and liposomes, have enhanced the efficacy and penetration of active ingredients, leading to better clinical outcomes.</div><div>In addition to topical treatments, recent studies have highlighted the efficacy of emerging modalities such as fractional lasers, intense pulsed light (IPL), and microneedling in the management of melasma. These techniques offer precise targeting of melanin without causing significant epidermal damage, thus minimizing the risk of post-inflammatory hyperpigmentation. Moreover, advances in oral medications have shown encouraging results in reducing melanin production and preventing melasma recurrence.</div><div>In conclusion, current advances in melasma management provide great opportunities for improving outcomes and increasing patient satisfaction. A multidisciplinary approach integrating dermatologists, cosmetic surgeons, and skincare professionals is essential for designing comprehensive and individualized treatment regimens. These advancements underscore the potential for improving patient outcomes and satisfaction while emphasizing the need for robust research to optimize therapeutic strategies.</div></div>","PeriodicalId":73214,"journal":{"name":"Health sciences review (Oxford, England)","volume":"14 ","pages":"Article 100213"},"PeriodicalIF":0.0,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143156608","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Deciphering the intricacies of immune system dysfunction and its impact on diabetes mellitus: Revisiting the communication strategies to manage diabetes mellitus","authors":"Vaibhav ,&nbsp;Saikh Shireen Nishad ,&nbsp;Dipali Dongare ,&nbsp;Adhrit Chandra Pati Tripathi ,&nbsp;Tripti Tripathi ,&nbsp;Pratima Tripathi","doi":"10.1016/j.hsr.2024.100201","DOIUrl":"10.1016/j.hsr.2024.100201","url":null,"abstract":"<div><div>Type 2 diabetes mellitus (T2DM) is a prevalent chronic condition, accounting for over 90% of diabetes cases globally, characterized by insulin resistance and chronic hyperglycemia. Beyond metabolic dysfunction, T2DM is associated with significant immune system alterations, including impaired macrophage, neutrophil, and natural killer cell functions. These immune dysfunctions contribute to increased susceptibility to infections, inflammation, and complications in diabetic individuals. Chronic hyperglycemia triggers an inflammatory response that weakens the body's immune defenses, further complicating disease management. This review delves into the intricate interplay between T2DM and the immune system, emphasizing how immune cell dysfunction exacerbates insulin resistance and impacts infection control. It also explores the role of pro-inflammatory markers and cellular responses in T2DM pathophysiology. Additionally, the article examines innovative strategies for managing T2DM, such as personalized medicine, telemedicine, and artificial intelligence. Personalized medicine tailors treatment to individual genetic, environmental, and lifestyle factors, while telemedicine facilitates remote monitoring and care. Artificial intelligence aids in early detection, personalized treatment plans, and enhanced patient management. By addressing both immune system alterations and advanced management strategies, this article provides a comprehensive understanding of T2DM and advocates for a more integrated approach to improve outcomes and patient care.</div></div>","PeriodicalId":73214,"journal":{"name":"Health sciences review (Oxford, England)","volume":"13 ","pages":"Article 100201"},"PeriodicalIF":0.0,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142327792","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Screening for pancreatic cancer among smokers as high-risk individuals: Systematic review and meta-analysis of prospective cohort studies","authors":"Melissa M. Elder ,&nbsp;Yves Paul Vincent Mbous ,&nbsp;Toni Marie Rudisill ,&nbsp;George A. Kelley","doi":"10.1016/j.hsr.2024.100203","DOIUrl":"10.1016/j.hsr.2024.100203","url":null,"abstract":"&lt;div&gt;&lt;h3&gt;Objective&lt;/h3&gt;&lt;div&gt;The main objective of this study was to conduct an aggregate data systematic review with meta-analysis of prospective cohort studies to determine the association between imaging screening for smoking and early diagnosis of pancreatic cancer (PC).&lt;/div&gt;&lt;/div&gt;&lt;div&gt;&lt;h3&gt;Methods&lt;/h3&gt;&lt;div&gt;Eligible studies included the following: 1) prospective cohort studies conducted in humans, 2) appropriate imaging screening method, 3) participants categorized into smoking as a high-risk group with no reported genetic disposition for PC, 4) no prior diagnosis of PC, 5) studies which detected and diagnosed adenocarcinoma following baseline screening, 6) data available for our primary outcome, PC, 7) studies published in the English language from January 1, 1992 to July 22, 2024. Any studies not meeting all of the above criteria were excluded. Information sources included the following: 1) PubMed, 2) CINAHL, 3) Scopus, 4) Cochrane Central Register of Controlled Trials (CENTRAL), 5) NIH National Cancer Institute's Division of Cancer Prevention, 6) Pancreatic Cancer Action Network, 7) ProQuest, 8) The British Medical Journal's &lt;em&gt;Gut&lt;/em&gt; and &lt;em&gt;Pancreatology&lt;/em&gt;, 9) Clinicaltrials.gov. The date of the last search (PubMed) was conducted on July 22, 2024. Risk of bias was assessed using the Cochrane Collaborations Risk Of Bias In Non-randomized Studies of Exposures [&lt;span&gt;&lt;span&gt;2&lt;/span&gt;&lt;/span&gt;] instrument. Small-study effects (publication bias, etc.) was assessed using the Doi plot and LFK index. The effect size metric for the primary outcome, PC, was the odds ratio (OR). Odd's ratios were pooled using the inverse-variance (IVhet) model. The strength/certainty of evidence was assessed using the Grading of Recommendations, Assessment, Development, and Evaluations (GRADE) instrument.&lt;/div&gt;&lt;/div&gt;&lt;div&gt;&lt;h3&gt;Results&lt;/h3&gt;&lt;div&gt;Five retrospective cohort studies representing 3,517 patients met the criteria for inclusion, 944 of whom were smokers. Two of the five studies reported the exact diagnosis stage for smokers. Among cases of pancreatic cancer (&lt;em&gt;n&lt;/em&gt; = 34), the estimated effect of smoking suggested harm (OR = 2.24, 95 % CI, 0.96 to 5.23) though with weak statistical significance (&lt;em&gt;p&lt;/em&gt; = 0.06). Statistically significant heterogeneity (&lt;em&gt;Q&lt;/em&gt; = 11.1, &lt;em&gt;p&lt;/em&gt; = 0.03) and moderate inconsistency (&lt;em&gt;I&lt;sup&gt;2&lt;/sup&gt;&lt;/em&gt; = 63.9 %, 95 % CI, 5.0 to 86.3 %) were observed. The 95 % prediction interval (PI) was 0.15 to 32.38. Risk of bias, based on ROBINS-E ranged from high to very high, with very low certainty of evidence based on the GRADE assessment.&lt;/div&gt;&lt;/div&gt;&lt;div&gt;&lt;h3&gt;Conclusions&lt;/h3&gt;&lt;div&gt;While not statistically significant, our findings suggest that smokers may be at an increased odds of having pancreatic cancer. However, these findings need to be interpreted with respect to the high risk of bias and very low certainty of evidence observed. A need exists for additional, well-designed studies that include intentional assessment of scr","PeriodicalId":73214,"journal":{"name":"Health sciences review (Oxford, England)","volume":"13 ","pages":"Article 100203"},"PeriodicalIF":0.0,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142572082","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The impact of reduced perineal lacerations during delivery: A systematic review","authors":"Li-Li Chen ,&nbsp;Meei-Ling Gau ,&nbsp;Mei-Zen Huang ,&nbsp;Chin-Hsing Tsai ,&nbsp;Fang-Ting Chang","doi":"10.1016/j.hsr.2024.100204","DOIUrl":"10.1016/j.hsr.2024.100204","url":null,"abstract":"<div><div>Various interventions to reduce perineal lacerations during childbirth have been reported, but no systematic assessment of each intervention's impact has been conducted. This study conducted an umbrella review to describe and categorize various interventions for preventing perineal lacerations and evaluate their outcomes.</div><div>The review included studies on perineal laceration interventions during childbirth from existing quantitative systematic reviews, with or without meta-analysis. A comprehensive search conducted up to September 2023 spanned eight bibliometric databases and gray literature sources. Two reviewers independently assessed five systematic reviews using the Joanna Briggs Institute checklist and extracted data with a standardized tool. Findings were summarized in a tabular format with supporting text.</div><div>Of the 57 articles initially shortlisted, six were selected for in-depth analysis. These reviews included 77 randomized controlled trials involving 27,782 patients. Perineal massages and antenatal pelvic floor exercises were identified as the most effective interventions, both of which shortened the second stage of labor and reduced laceration rates. The efficacy of other interventions remains uncertain due to limited research. Future studies should explore the impact of varying intensities and frequencies of perineal massages throughout pregnancy. Integrating these practices into antenatal education and routine midwifery care could further improve clinical outcomes and prevent perineal lacerations during labor.</div></div>","PeriodicalId":73214,"journal":{"name":"Health sciences review (Oxford, England)","volume":"13 ","pages":"Article 100204"},"PeriodicalIF":0.0,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142534685","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Revitalizing respiration: A comprehensive review of oxygen therapy in interstitial lung diseases","authors":"Alaa Ramadan ,&nbsp;Alaa R. Ashour ,&nbsp;Alaa M. Sadek ,&nbsp;Esraa Zakaria ,&nbsp;Eman Zakaria ,&nbsp;Aya Abdelhafez Hasan ,&nbsp;Doaa A. Salah ,&nbsp;Omnia Abdelfattah ,&nbsp;Aml Kamal ,&nbsp;Esraa Salah ,&nbsp;Abdelrahman M. Elettreby ,&nbsp;Mohamed Abouzid ,&nbsp;Amogh verma ,&nbsp;Nathan Ezie Kengo ,&nbsp;Eptehal Dongol","doi":"10.1016/j.hsr.2024.100202","DOIUrl":"10.1016/j.hsr.2024.100202","url":null,"abstract":"<div><div>Interstitial Lung Diseases (ILDs) encompass a diverse group of disorders characterised by inflammation and fibrosis, leading to significant impairment in lung function and quality of life. With the increasing prevalence of ILDs, managing these conditions has become a pressing medical and economic challenge. Oxygen therapy is crucial in ILD management, offering benefits beyond hypoxemia correction, including symptom relief and potential influence on disease progression. However, patient compliance, long-term use, side effects, and the psychosocial impact of therapy present ongoing challenges. This narrative review examines the critical role of oxygen therapy in ILDs, highlighting its current applications, associated challenges, and emerging innovations such as targeted therapies, personalized oxygen delivery, and advancements in technology that promise to enhance patient care in this complex field.</div></div>","PeriodicalId":73214,"journal":{"name":"Health sciences review (Oxford, England)","volume":"13 ","pages":"Article 100202"},"PeriodicalIF":0.0,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142427387","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A Four-Year Journey of Health Sciences Review with Innovation and Growth","authors":"Burcin Ekser","doi":"10.1016/j.hsr.2024.100207","DOIUrl":"10.1016/j.hsr.2024.100207","url":null,"abstract":"","PeriodicalId":73214,"journal":{"name":"Health sciences review (Oxford, England)","volume":"13 ","pages":"Article 100207"},"PeriodicalIF":0.0,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143128673","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"An integrative review of cancer-related cachexia and sarcopenia: A different focus in malignant hematology","authors":"Sara M. Tinsley-Vance ,&nbsp;Tina M. Mason ,&nbsp;Rami S. Komrokji","doi":"10.1016/j.hsr.2024.100205","DOIUrl":"10.1016/j.hsr.2024.100205","url":null,"abstract":"<div><h3>Introduction/background</h3><div>An improved understanding of cancer-related cachexia and sarcopenia among patients with hematologic malignancies can improve their health outcomes. Patients with hematologic malignancies are affected by cancer-related cachexia and sarcopenia, but this aspect of their care is rarely studied. This review aims to increase awareness and knowledge of cancer-related cachexia and sarcopenia for patients with hematologic malignancies through a comprehensive synthesis of current research.</div></div><div><h3>Methods</h3><div>An integrative literature review was conducted according to the Preferred Reporting Items for Systematic Reviews and Meta-Analyses. Ovid MEDLINE, CINAHL Complete, Embase, and Web of Science databases were searched for studies published between 2012 and 2022 using search terms of hematologic malignancies and cancer-related cachexia or sarcopenia.</div></div><div><h3>Results</h3><div>Twenty-nine studies were examined with data on 5,687 patients, primarily diffuse large B-cell lymphoma.</div></div><div><h3>Conclusion</h3><div>The results are grouped by themes identified in the studies of cancer-related cachexia and sarcopenia in hematologic cancers. The major themes identified were health outcomes, patient identification, transplant effects, and sex differences. Cancer-related cachexia and sarcopenia are associated with decreased overall survival and progression-free survival, similar to solid tumors. Cancer-related cachexia and sarcopenia reduce tolerance to chemotherapy and increase hematologic toxicities. With this effect, biomarkers and cachexia prognostic scores are available to improve patient identification, prognostication, and support. These affected individuals will benefit from increased awareness by the healthcare team to tailor care and mitigate the deleterious effects of the condition.</div></div>","PeriodicalId":73214,"journal":{"name":"Health sciences review (Oxford, England)","volume":"13 ","pages":"Article 100205"},"PeriodicalIF":0.0,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142706869","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}