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A case of anterior scleritis in association with posterior scleritis – a diagnostic riddle 前巩膜炎合并后巩膜炎1例-一个诊断难题
GMS ophthalmology cases Pub Date : 2022-02-08 DOI: 10.3205/oc000188
Aditi G Dastidar, Sugandha Goel, D. Kundu, J. Biswas, E. Nigam, Preeti Sharma
{"title":"A case of anterior scleritis in association with posterior scleritis – a diagnostic riddle","authors":"Aditi G Dastidar, Sugandha Goel, D. Kundu, J. Biswas, E. Nigam, Preeti Sharma","doi":"10.3205/oc000188","DOIUrl":"https://doi.org/10.3205/oc000188","url":null,"abstract":"We herein report a case of a young female presenting with multiple nodular scleral abscesses mimicking infective scleritis with exudative retinal detachment. Repeated diagnostic scraping for microbiological and histopathological analysis was inconclusive. The patient’s systemic and collagen disease work-up was non-contributory. She was treated with multiple surgical debridement and de-roofing of the abscesses along with antibiotic irrigation. Topical and oral steroid was stopped on worsening of the condition, and the patient was maintained on topical and oral antibiotics. Complete resolution of scleritis and exudative detachment was noted at 1 month follow-up and no recurrence was noted until 6 months.","PeriodicalId":73178,"journal":{"name":"GMS ophthalmology cases","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-02-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43992211","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Intravitreal melphalan for persistent retinoblastoma vitreous seeds 玻璃体内melphalan治疗持续性视网膜母细胞瘤
GMS ophthalmology cases Pub Date : 2022-02-08 DOI: 10.3205/oc000190
Marie Jeazelle H. Redondo-Villanueva, G. V. Mercado
{"title":"Intravitreal melphalan for persistent retinoblastoma vitreous seeds","authors":"Marie Jeazelle H. Redondo-Villanueva, G. V. Mercado","doi":"10.3205/oc000190","DOIUrl":"https://doi.org/10.3205/oc000190","url":null,"abstract":"A 7-month-old male presented with bilateral retinoblastoma, initially group E OD and group C OS (International Intraocular Retinoblastoma Classification). The patient underwent enucleation with adjuvant chemotherapy and radiotherapy on the right eye for extraocular retinoblastoma. The main tumors on the left eye regressed with combined neoadjuvant chemotherapy with focal therapy, but had persistent sphere vitreous seeds overlying the tumor at the superotemporal mid-periphery and at the inferior periphery. Intravitreal injection of melphalan was performed. Vitreous seeds were clinically undetectable after 2 cycles of injection. Six months from the 2nd intravitreal injection of melphalan, there was no evidence of new tumors nor vitreous seeds in the left eye. No documented complications of intravitreal melphalan injection were experienced. This is the first documented successful treatment of vitreous seeds with intravitreal melphalan at the Ocular Oncology/Retinoblastoma Unit of the University of the Philippines, Philippine General Hospital.","PeriodicalId":73178,"journal":{"name":"GMS ophthalmology cases","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-02-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44667132","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Visual complaints in pregnancy: (pre)eclampsia as a chameleon. 孕期视觉主诉:(先兆)子痫像变色龙。
GMS ophthalmology cases Pub Date : 2022-01-01 DOI: 10.3205/oc000208
Johanna Wiedemann, Lebriz Altay, Antje Neugebauer, Tim Krohne, Claus Cursiefen
{"title":"Visual complaints in pregnancy: (pre)eclampsia as a chameleon.","authors":"Johanna Wiedemann, Lebriz Altay, Antje Neugebauer, Tim Krohne, Claus Cursiefen","doi":"10.3205/oc000208","DOIUrl":"https://doi.org/10.3205/oc000208","url":null,"abstract":"Objective: The visual system often is affected in patients with preeclampsia and even more in cases of eclampsia, a life-threatening pregnancy complication. Symptoms include blurred vision and deterioration of visual acuity. Pregnancy can also affect pre-existing conditions, such as diabetic retinopathy. In this case series, we describe three patients with the same underlying condition, i.e. (pre)eclampsia who experienced acute visual disturbance whereas the final diagnosis was different: disseminated intravascular coagulopathy (DIC), posterior reversible encephalopathy syndrome (PRES), and diabetic retinopathy. Methods and results: All patients underwent a thorough slit lamp examination and ocular coherence tomography (OCT). All patients presented with acute impaired vision and subretinal fluid and-/or fibrin. Conclusions: These cases highlight the importance of early involvement of ophthalmologists when pregnant women complain about visual disorders.","PeriodicalId":73178,"journal":{"name":"GMS ophthalmology cases","volume":"12 ","pages":"Doc21"},"PeriodicalIF":0.0,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9762176/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10439264","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Hemi-central retinal artery occlusion following methanol toxicity. 甲醇中毒后半中央视网膜动脉闭塞。
GMS ophthalmology cases Pub Date : 2022-01-01 DOI: 10.3205/oc000207
Mohammad Zarei, Sima Sheikhghomi, Masoud Aghsaei Fard
{"title":"Hemi-central retinal artery occlusion following methanol toxicity.","authors":"Mohammad Zarei,&nbsp;Sima Sheikhghomi,&nbsp;Masoud Aghsaei Fard","doi":"10.3205/oc000207","DOIUrl":"https://doi.org/10.3205/oc000207","url":null,"abstract":"<p><strong>Objective: </strong>To describe a patient with hemi-retinal artery occlusion following methanol toxicity.</p><p><strong>Methods: </strong>Observational case report.</p><p><strong>Results: </strong>We report a case presented with an acute altitudinal visual field loss in the right eye following consumption of illicit alcoholic drink. In fundus photography, a well demarcated superior hemi-retinal whitening with foveal sparing was noted. Careful inspection of the optic nerve head in the right eye revealed that there was no main trunk of the central retinal artery anterior to the lamina cribrosa. Two separately emerging superior and inferior arterial trunks were noted. In fundus fluorescein angiography, earlier dye filling in the territory of the superior arterial trunk compared to the inferior arterial trunk was evident.</p><p><strong>Conclusion: </strong>Hemi-central retinal occlusion may happen as an ocular consequence of methanol toxicity in patients with a proximal bifurcation of the central retinal artery.</p>","PeriodicalId":73178,"journal":{"name":"GMS ophthalmology cases","volume":"12 ","pages":"Doc20"},"PeriodicalIF":0.0,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9762174/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10439263","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Active removal of anterior segment-migrated dexamethasone implant (Ozurdex®) 主动移除前段移位地塞米松植入物（Ozurdex®）
GMS ophthalmology cases Pub Date : 2021-12-28 DOI: 10.3205/oc000195
Jozef Adelson M. Depla, M. Veckeneer, I. Bleyen
{"title":"Active removal of anterior segment-migrated dexamethasone implant (Ozurdex®)","authors":"Jozef Adelson M. Depla, M. Veckeneer, I. Bleyen","doi":"10.3205/oc000195","DOIUrl":"https://doi.org/10.3205/oc000195","url":null,"abstract":"Background: Ozurdex® (Allergan plc., Dublin, Ireland) is an intravitreal sustained-release dexamethasone (DEX) implant. The implant has been reported to migrate into the anterior chamber, potentially causing corneal decompensation. Prompt removal or relocation in the vitreous cavity is advised but troublesome due to its fragility. Several techniques exist, but elaborate setup and specialized surgical skills that are required may cause delay in treatment. We report a novel technique that avoids these shortcomings. Case presentation: A 59-year-old woman presented to the emergency department with visual loss due to an anterior chamber-migrated DEX implant and corneal edema. Using an ophthalmic viscosurgical device (OVD) and a bent 19-gauge needle, the implant has promptly been removed in a one-minute procedure under topical anesthesia. Conclusion: Aspirating an anterior chamber-migrated DEX implant using a 19-gauge bent needle is a cost-effective, time-efficient and safe technique, not requiring specialized surgical skills.","PeriodicalId":73178,"journal":{"name":"GMS ophthalmology cases","volume":"12 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-12-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49599786","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Unilateral simultaneous optic nerve and choroidal infiltration - unusual presentation of metastatic disease in breast carcinoma. 单侧视神经和脉络膜同时浸润——乳腺癌转移性疾病的不寻常表现。
GMS ophthalmology cases Pub Date : 2021-09-21 eCollection Date: 2021-01-01 DOI: 10.3205/oc000187
Poninder Kumar, Ashok Kumar, Srujana Dubakka, Jaya Kaushik, Mohini Agrawal
{"title":"Unilateral simultaneous optic nerve and choroidal infiltration - unusual presentation of metastatic disease in breast carcinoma.","authors":"Poninder Kumar,&nbsp;Ashok Kumar,&nbsp;Srujana Dubakka,&nbsp;Jaya Kaushik,&nbsp;Mohini Agrawal","doi":"10.3205/oc000187","DOIUrl":"https://doi.org/10.3205/oc000187","url":null,"abstract":"<p><p>Breast carcinoma metastasis can involve any ocular structures, but involvement of the optic nerve is extremely rare. Choroidal metastasis is usually multifocal as well as bilateral and occurs late. We report an unusual initial presentation of metastasis from breast cancer; unilateral infiltrative optic neuropathy with concurrent choroid metastatic deposits in an adequately treated middle-aged female. Our present case, wherein for the first time in the literature, we illustrated unilateral infiltrative optic neuropathy and choroidal metastatic deposits secondary to breast carcinoma, will increase our knowledge about the various potential ocular presentations of this relatively common malignant disease.</p>","PeriodicalId":73178,"journal":{"name":"GMS ophthalmology cases","volume":"11 ","pages":"Doc14"},"PeriodicalIF":0.0,"publicationDate":"2021-09-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8495234/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39519115","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Ocular trauma or Oedipism: completing the evisceration. 眼外伤或恋母癖:完成内脏取出。
GMS ophthalmology cases Pub Date : 2021-08-04 eCollection Date: 2021-01-01 DOI: 10.3205/oc000186
Ujjwala Narang, Laura Maubon, Vishal Shah, Vijay Wagh
{"title":"Ocular trauma or Oedipism: completing the evisceration.","authors":"Ujjwala Narang,&nbsp;Laura Maubon,&nbsp;Vishal Shah,&nbsp;Vijay Wagh","doi":"10.3205/oc000186","DOIUrl":"https://doi.org/10.3205/oc000186","url":null,"abstract":"<p><p>Self-enucleation, also known as Oedipism, is a rare form of ocular trauma. The objective of this clinical case report is to highlight the importance of diagnosing this unusual injury and thus ensuring its appropriate management. We herein describe a case of a 58-year-old man who presented to hospital with a bleeding left eye. Initially, limited history was provided, however, on further enquiry it was revealed that he had paranoid schizophrenia. The patient eventually had to be sectioned with assistance from the Police and Psychiatry team, upon discovery of self-inflicted mechanism of injury. Subsequently, the patient had evisceration of the left eye and afterwards, demonstrated insight into the pre-operative problems. Literature review emphasizes the importance of close cooperation required between medical specialities to ensure that the underlying cause, usually schizophrenia, is managed in conjunction to the eye injury in order to provide optimum care for the patient.</p>","PeriodicalId":73178,"journal":{"name":"GMS ophthalmology cases","volume":"11 ","pages":"Doc13"},"PeriodicalIF":0.0,"publicationDate":"2021-08-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8422941/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39430091","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Miliary tuberculosis presenting as bilateral pseudo-retinoblastoma. 军人结核表现为双侧假视网膜母细胞瘤。
GMS ophthalmology cases Pub Date : 2021-07-28 eCollection Date: 2021-01-01 DOI: 10.3205/oc000185
Yamini Attiku, Pukhraj Rishi
{"title":"Miliary tuberculosis presenting as bilateral pseudo-retinoblastoma.","authors":"Yamini Attiku,&nbsp;Pukhraj Rishi","doi":"10.3205/oc000185","DOIUrl":"https://doi.org/10.3205/oc000185","url":null,"abstract":"<p><p><b>Objective:</b> To describe an interesting case of miliary tuberculosis mimicking retinoblastoma. <b>Method:</b> A retrospective case report. <b>Result:</b> The twin brother of a known case of retinobastoma presented with headache. On fundus examination, multiple yellowish-white lesions were noted in both eyes. Magnetic resonance imaging of the brain showed multiple enhancing lesions. A diagnosis of miliary tuberculosis was made and anti-tubercular therapy was started. <b>Conclusion:</b> Ocular tuberculosis can mimic retinoblastoma and lead to diagnostic dilemma especially in cases with family history of retinoblastoma.</p>","PeriodicalId":73178,"journal":{"name":"GMS ophthalmology cases","volume":"11 ","pages":"Doc12"},"PeriodicalIF":0.0,"publicationDate":"2021-07-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8422939/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39431105","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Acute anterior uveitis after topical interferon for conjunctival intraepithelial neoplasia (CIN). 结膜上皮内瘤变(CIN)局部干扰素治疗后急性前葡萄膜炎。
GMS ophthalmology cases Pub Date : 2021-07-20 eCollection Date: 2021-01-01 DOI: 10.3205/oc000184
Ameay V Naravane, Jacquelyn Weber, Grishma Barucha, Joshua H Hou
{"title":"Acute anterior uveitis after topical interferon for conjunctival intraepithelial neoplasia (CIN).","authors":"Ameay V Naravane,&nbsp;Jacquelyn Weber,&nbsp;Grishma Barucha,&nbsp;Joshua H Hou","doi":"10.3205/oc000184","DOIUrl":"https://doi.org/10.3205/oc000184","url":null,"abstract":"<p><p><b>Objective:</b> Ocular surface squamous neoplasia (OSSN) is the most common type of non-melanocytic ocular surface tumor. Conjunctival intraepithelial neoplasia (CIN) is a type of OSSN that be medically managed by either topical interferon alpha-2b (IFN α-2b), 5-fluorouracil (5-FU), or mitomycin C. While a paradoxical response to IFN α-2b in the HIV population has been reported, we report a case of a paradoxical response in an immunocompetent individual. <b>Methods:</b> A 65-year-old immunocompetent female presents to the clinic with CIN. <b>Results:</b> She is started on topical IFN α-2b, resulting in an unexpected hypopyon, increased corneal epithelial defect, and increased size of the lesion. Switching to topical 5-FU resulted in decreasing size of the CIN lesion and resolution of the epithelial defect. <b>Conclusions:</b> Topical IFN α-2b can produce a paradoxical worsening of CIN lesions in some patients. Providers should be aware of this reaction, as well as the presenting signs and symptoms, to make appropriate treatment changes when treating CIN.</p>","PeriodicalId":73178,"journal":{"name":"GMS ophthalmology cases","volume":"11 ","pages":"Doc11"},"PeriodicalIF":0.0,"publicationDate":"2021-07-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8422938/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39431104","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 2
Infectious crystalline keratitis induced by Citrobacter. 柠檬酸杆菌诱导的感染性结晶性角膜炎。
GMS ophthalmology cases Pub Date : 2021-05-17 eCollection Date: 2021-01-01 DOI: 10.3205/oc000182
Zeba Khanam, Gaganjeet Singh Gujral, Shariq Wadood Khan
{"title":"Infectious crystalline keratitis induced by Citrobacter.","authors":"Zeba Khanam,&nbsp;Gaganjeet Singh Gujral,&nbsp;Shariq Wadood Khan","doi":"10.3205/oc000182","DOIUrl":"https://doi.org/10.3205/oc000182","url":null,"abstract":"<p><p><b>Background:</b> Microbial keratitis is an important cause of ocular morbidity, with emerging organisms and drug resistance posing a real threat to vision of patients. <b>Case presentation:</b> A 30-year-old female presented with infective keratitis in the left eye. She had been using rose nectar as home remedy for her ailment. With no improvement in her symptoms, she presented to the eye emergency department, where she was started on empirical therapy with moxifloxacin, which was shifted to levofloxacin eye drops after the antimicrobial susceptibility test results came in. Microbiological examination revealed infection with rare gram-negative bacilli <i>Citrobacter koseri</i>. The patient responded well to the treatment with 1.5% levofloxacin eye drops and her vision improved from 20/120 to 20/30 over a course of 3 months. <b>Conclusion:</b> Treatment of microbial keratitis with those antibiotics that the organism is most sensitive to is of paramount importance today, where we often find patients on a cocktail of eye drops, which leads to further resistance and vision deterioration. Culturing of cornea scrapings and antimicrobial susceptibility testing of the isolated organism is now the standard guideline to be followed in the investigation of microbial keratitis.</p>","PeriodicalId":73178,"journal":{"name":"GMS ophthalmology cases","volume":"11 ","pages":"Doc09"},"PeriodicalIF":0.0,"publicationDate":"2021-05-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8167372/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39092028","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 4
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