柠檬酸杆菌诱导的感染性结晶性角膜炎。

GMS ophthalmology cases Pub Date : 2021-05-17 eCollection Date: 2021-01-01 DOI:10.3205/oc000182
Zeba Khanam, Gaganjeet Singh Gujral, Shariq Wadood Khan
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引用次数: 4

摘要

背景:微生物角膜炎是眼部发病的重要原因,新出现的微生物和耐药性对患者的视力构成了真正的威胁。病例介绍:一名30岁女性左眼感染性角膜炎。她一直用玫瑰花蜜作为治疗疾病的家庭疗法。由于症状没有改善,她被送到眼科急诊科,在那里她开始接受莫西沙星的经验性治疗,在抗生素敏感性试验结果出来后,她被改为左氧氟沙星滴眼液。微生物学检查发现感染了罕见的革兰氏阴性杆菌克氏柠檬酸杆菌。患者对1.5%左氧氟沙星滴眼液治疗反应良好,3个月后视力由20/120改善至20/30。结论:使用微生物最敏感的抗生素治疗微生物角膜炎在今天是至关重要的,我们经常发现患者使用鸡尾酒眼药水,这导致进一步的抵抗和视力恶化。角膜刮屑的培养和分离的微生物的抗菌药物敏感性试验现在是调查微生物角膜炎的标准指南。
本文章由计算机程序翻译,如有差异,请以英文原文为准。

Infectious crystalline keratitis induced by Citrobacter.

Infectious crystalline keratitis induced by Citrobacter.

Infectious crystalline keratitis induced by Citrobacter.

Infectious crystalline keratitis induced by Citrobacter.

Background: Microbial keratitis is an important cause of ocular morbidity, with emerging organisms and drug resistance posing a real threat to vision of patients. Case presentation: A 30-year-old female presented with infective keratitis in the left eye. She had been using rose nectar as home remedy for her ailment. With no improvement in her symptoms, she presented to the eye emergency department, where she was started on empirical therapy with moxifloxacin, which was shifted to levofloxacin eye drops after the antimicrobial susceptibility test results came in. Microbiological examination revealed infection with rare gram-negative bacilli Citrobacter koseri. The patient responded well to the treatment with 1.5% levofloxacin eye drops and her vision improved from 20/120 to 20/30 over a course of 3 months. Conclusion: Treatment of microbial keratitis with those antibiotics that the organism is most sensitive to is of paramount importance today, where we often find patients on a cocktail of eye drops, which leads to further resistance and vision deterioration. Culturing of cornea scrapings and antimicrobial susceptibility testing of the isolated organism is now the standard guideline to be followed in the investigation of microbial keratitis.

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