Acta Odontologica Scandinavica最新文献

{"title":"Dental and periodontal condition by sociodemographics in Finnish adults in 2023: cross-sectional results from the Healthy Finland Survey.","authors":"Anna Liisa Suominen, Anni Leskinen, Tuomas Saxlin, Ulla Palotie, Ulvi Kahraman Gursoy, Kirsi Sipilä, Jaana Rautava, Timo Peltomäki, Annamari Lundqvist, Ulla Harjunmaa","doi":"10.2340/aos.v84.44370","DOIUrl":"10.2340/aos.v84.44370","url":null,"abstract":"<p><strong>Objective: </strong>To obtain current information of adult's dental and periodontal condition and contributing sociodemographic factors.</p><p><strong>Material and methods: </strong>Clinical examinations were conducted in 2023 (n = 1,798). Enamel and dentine caries prevalences were recorded as the percentages of those having at least one tooth with enamel or dentine caries, and prevalence of periodontitis as those having at least two teeth with clinical attachment loss of ≥ 4 mm or with a probing pocket depth (PPD) of ≥ 6 mm. The numbers of teeth with enamel caries, dentine caries, and PPD (≥ 4 and ≥ 6 mm) indicated the extent of dental and periodontal disease. Sociodemographic factors included age, sex, educational level, and native language.</p><p><strong>Results: </strong>Two-thirds of the participants had nearly full dentition. Of the dentate participants, 39% had dentine caries and 92% had enamel caries. Periodontitis was detected in 27%, teeth with PPD ≥ 4 mm in 74%, and bleeding on probing in 91% of the dentate participants. Male sex, older age, a lower educational level, and a native language other than Finnish or Swedish were significantly associated with indicators of poorer dental and periodontal conditions in this study - except for extent of enamel caries. The number of teeth affected by enamel caries was highest among younger age groups.</p><p><strong>Conclusion: </strong>Dental caries and periodontal diseases remain significant health concern among Finnish adults, as do sociodemographic disparities. These findings underscore the importance of implementing targeted preventive interventions for the identified risk groups.</p>","PeriodicalId":7313,"journal":{"name":"Acta Odontologica Scandinavica","volume":"84 ","pages":"457-470"},"PeriodicalIF":1.9,"publicationDate":"2025-08-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144870821","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Health literacy and oral health-related behaviors among young adults in Norway.","authors":"Lene Marita Steinvik, Gro Eirin Holde, Hanne S Finbråten, Elin K Evensen, Linda Maria Stein","doi":"10.2340/aos.v84.44230","DOIUrl":"10.2340/aos.v84.44230","url":null,"abstract":"<p><strong>Objective: </strong>The transition from adolescence to adulthood represents an increase in autonomy and responsibility of oral health-related behaviors, in which health literacy might play a significant role. The objective of the study was to assess health literacy in a young adult population and determine whether health literacy is associated with their oral health-related behaviors.  Materials and methods: Utilizing data from the Fit Futures longitudinal cohort study, this cross-sectional analysis was based on self-administered questionnaires from the third wave, FF3. Health literacy was assessed using a short version of the European Health Literacy Survey Questionnaire (HLS-Q12), while oral health-related behaviors were assessed through toothbrushing frequency and dental service utilization. In addition, socioeconomic factors were included as control variables. Bivariate analyses and multivariable logistic regression were performed.  Results: The findings indicated that 38% of the young adults had a score equivalent to having lower levels of health literacy. Higher health literacy scores were associated with more regular dental service use, even after adjusting for socioeconomic covariates.  Conclusion: Although most young adults had good oral health-related behaviors, it is concerning that a significant proportion still neglects regular dental visits and consistent tooth brushing. These findings highlight the need for greater emphasis on health literacy within public dental health services.</p>","PeriodicalId":7313,"journal":{"name":"Acta Odontologica Scandinavica","volume":"84 ","pages":"439-445"},"PeriodicalIF":1.9,"publicationDate":"2025-08-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12371751/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144854136","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"An explorative study on the interaction of cyclin-dependent kinase inhibitor 2B antisense RNA 1 (CDKN2B-AS1/ANRIL) gene polymorphism with obesity on periodontitis among Norwegian adults.","authors":"Natalia Petrenya, Laila A Hopstock, Elin Hadler-Olsen, Farah Asa'ad, Lena Larsson, Svetlana N Zykova, Gro Eirin Holde, Alexandre R Vieira, Birgitta Jönsson","doi":"10.2340/aos.v84.44368","DOIUrl":"10.2340/aos.v84.44368","url":null,"abstract":"<p><p>Objective ANRIL is a pleiotropic gene with a strong link to periodontitis. ANRIL gene variant rs1537373 is associated with altered CDKN2B gene expression, which is linked to obesity. In this explorative, cross-sectional population-based study, we aimed to investigate the hypothesis that ANRIL (rs1537373) T>G may be associated with periodontitis through interactions, focusing on rs1537373×obesity interaction. Methods Genotyping for ANRIL (rs1537373), and clinical and periodontal examination were performed in 3554 participants (aged 40-93 years, 52% women) from the seventh survey of the Tromsø Study (2015-2016), Norway. We defined periodontitis stage based on radiographic bone loss (2018 AAP/EFP classification). Results The individual association between rs1537373 and periodontitis, as well as multiplicative and additive interactions between rs1537373 and age, sex, smoking, and obesity on periodontitis under a recessive model were studied. We found multiplicative and additive interactions between rs1537373 and obesity. When compared with GT/TT genotype and no obesity, GG genotype and obesity was associated with higher odds for periodontitis stage III-IV (OR=2.47, 95%CI=1.48-4.12, p=0.001; relative excess risk due to interaction=1.51, 95%CI=0.26-2.77, p=0.018; attributable proportion due to interaction=0.61; 95%CI=0.35-0.87, p<0.001). Conclusion Our findings suggest that rs1537373 GG genotype and obesity were jointly associated with periodontitis stage III-IV in this Norwegian population.</p>","PeriodicalId":7313,"journal":{"name":"Acta Odontologica Scandinavica","volume":"84 ","pages":"426-438"},"PeriodicalIF":1.9,"publicationDate":"2025-08-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12372528/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144854135","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Oral rehabilitation with dental implants in patients with tooth agenesis: a retrospective study in Helsinki University Hospital, Helsinki, Finland.","authors":"Maria Mikkola, Anu Kiukkonen, Nina-Li Avellan, Patricia Stoor, Viivi Mattila, Jussi Oskari Furuholm, Timo Sorsa, Karita Nylund","doi":"10.2340/aos.v84.44181","DOIUrl":"10.2340/aos.v84.44181","url":null,"abstract":"<p><strong>Objective: </strong>The aims of this retrospective and descriptive study were to investigate oral rehabilitation with dental implants in tooth agenesis patients treated at Helsinki University Hospital, Finland, between 2015 and 2019, and to analyze implant survival and prosthetic complications within the first 2 years.  Material and methods: This study included 72 patients (42 oligodontia and 30 hypodontia). Data concerning general/oral health and implant treatment modalities were retrieved from hospital records.  Results: Patients were mostly systemically healthy nonsmokers with a mean age of 32.3 years at the time of implant placement. Orthodontic treatment was required for 77.7%, and 31.9% underwent also orthognathic surgery. Patients had 6.6 missing teeth on average and received 2.8 implants each, 205 in total. Tissue augmentation was needed in 64.4% of cases. Screw-retained suprastructures, mainly single crowns (76.4%), were used in 95.5% of cases, all with custom abutments. The mean follow-up time was 25.2 months, with one technical and one mechanical complication. No implants were lost.</p><p><strong>Conclusions: </strong>With multidisciplinary planning and collaboration, replacement of all teeth in tooth agenesis may not be required. In this study, despite an average of 6.6 missing teeth per patient, only 2.8 implants were placed on average.</p>","PeriodicalId":7313,"journal":{"name":"Acta Odontologica Scandinavica","volume":"84 ","pages":"418-425"},"PeriodicalIF":1.9,"publicationDate":"2025-08-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12362942/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144820351","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The causal associations of 25(OH)D and its metabolites with oropharyngeal cancer risk: a Mendelian randomization study.","authors":"YaoHui Yu, Yu Zhou","doi":"10.2340/aos.v84.44053","DOIUrl":"10.2340/aos.v84.44053","url":null,"abstract":"<p><strong>Background: </strong>Previous studies have suggested that there are distinct correlations of 25-hydroxyvitamin D (25(OH)D) and its metabolites with the risk of developing health conditions and cancer; however, the precise nature of these associations in patients with oropharyngeal cancer (OPC) is unknown. Our primary objective was to evaluate the causal impact of 25(OH)D and its metabolites, including 25(OH)D3 and its epimer C3-epi-25(OH)D3, on susceptibility to OPC through the use of Mendelian randomization (MR) methodology.</p><p><strong>Methods: </strong>Mendelian randomization analysis was performed on data from 291 patients with OPC from Europe, North America, and South America using genetic variant strongly related to C3-epi-25(OH)D3, 25(OH)D, and 25(OH)D3 exposure. The primary analytical method for two-sample MR analysis was inverse-variance weighting (IVW); supplemental analyses (weighted median [WM], MR-Egger) were also conducted. Leave-one-out and Cochran's Q tests were concurrently used as sensitivity analyses to test and adjust for pleiotropy.</p><p><strong>Results: </strong>Our MR analysis provided evidence suggesting that greater 25(OH)D3 levels are causally associated with a decreased risk of developing OPC within the European population (WM OR = 0.47, 95% CI = 0.24-0.91, p = 0.03). Only one of the 21 MR analyses yielded significant results; for this MR analysis, the IVW results were significant, but subsequent leave-one-out analyses revealed instability in the causal association. However, the association was significant when rs9304669 was excluded (OR = 0.51, 95% CI = 0.28-0.91, p = 0.02), whereas the other results were not statistically significant. The sensitivity analysis indicated that the results were reliable, with no observed heterogeneity or pleiotropy.</p><p><strong>Conclusions: </strong>There was no evidence that 25(OH)D, 25(OH)D3 or C3-epi-25(OH)D3 levels are associated with OPC risk or that 25OHD supplementation in the general population prevents OPC. The registration number is INPLASY202490081.</p>","PeriodicalId":7313,"journal":{"name":"Acta Odontologica Scandinavica","volume":"84 ","pages":"398-407"},"PeriodicalIF":1.9,"publicationDate":"2025-07-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12362939/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144648267","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Esthetic satisfaction vs. peri-implant health: a cautionary perspective.","authors":"Mohammad Majduddin Sulaiman, Adam Husein, Ikhwan Hakimi Mohamad","doi":"10.2340/aos.v84.44055","DOIUrl":"10.2340/aos.v84.44055","url":null,"abstract":"","PeriodicalId":7313,"journal":{"name":"Acta Odontologica Scandinavica","volume":"84 ","pages":"397"},"PeriodicalIF":1.4,"publicationDate":"2025-06-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12239004/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144482872","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Comparative outcomes of endodontically treated teeth versus dental implant-supported prostheses: a systematic review.","authors":"Miguel Fernando Borda, Salomón Páez-García, Luisa Fernanda Murcia, Luis Carlos Venegas-Sanabria, Miguel Germán Borda","doi":"10.2340/aos.v84.43871","DOIUrl":"10.2340/aos.v84.43871","url":null,"abstract":"<p><strong>Objective: </strong>The objective of this study was to compare the clinical and patient-related outcomes of root canal therapy (RCT) and dental implants (DIs) in managing severe tooth damage, supporting evidence-based treatment decisions.</p><p><strong>Material and methods: </strong>A systematic review was performed in accordance with PRISMA (Preferred Reporting Items for Systematic Reviews and Meta-Analyses) guidelines. Six databases were searched: Cochrane Library, Embase, Medline, LILACS, Scopus, and Web of Science. Studies comparing clinical and patient-reported outcomes in adult patients treated with either RCT or DIs were included. The Joanna Briggs Institute Critical Appraisal Checklists were used to assess the risk of bias. Due to significant heterogeneity among studies, meta-analysis was not feasible, and findings were synthesised qualitatively. PROSPERO registration: CRD42024584113.</p><p><strong>Results: </strong>Out of 1,876 initial records, 12 studies met inclusion criteria: 7 cohort studies, 4 case-control studies, and 1 randomised controlled trial. Most studies had low to moderate risk of bias. Both RCT and DIs demonstrated high survival rates, with RCT slightly outperforming DIs in terms of success. Failure rates ranged from 0.7% to 12.0%, with no significant differences between treatments. DIs were associated with a higher frequency of postoperative interventions and complications. Patient-reported outcomes such as pain, satisfaction, and quality of life (QoL) were comparable across both modalities.</p><p><strong>Conclusion: </strong>RCT and DIs both offer viable and effective solutions for restoring severely damaged teeth, with high survival and success rates and low failure rates. Both treatments were also associated with favourable patient-reported outcomes, including minimal pain, high satisfaction, and improved QoL. The decision between treatments should consider clinical factors, patient preferences, cost, accessibility, potential complications, and patient-centred outcomes. Shared decision-making is essential for optimal patient care.</p>","PeriodicalId":7313,"journal":{"name":"Acta Odontologica Scandinavica","volume":"84 ","pages":"386-396"},"PeriodicalIF":1.4,"publicationDate":"2025-06-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12239130/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144473737","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Expectations of orthodontic treatment among 7-12 year-old children - a cross sectional study.","authors":"Anne-Maria Aulu, Tuija Pikkusaari, David Rice, Heidi Arponen","doi":"10.2340/aos.v84.43910","DOIUrl":"https://doi.org/10.2340/aos.v84.43910","url":null,"abstract":"<p><strong>Objective: </strong>The primary aim of this study was to investigate participants' orthodontic treatment expectations and to assess participants' perceptions of their own orthodontic treatment need. A secondary aim was to compare participants' self-perceived treatment need to an orthodontist's opinion.</p><p><strong>Material and methods: </strong>In this cross-sectional study, a total of 98 participants, aged 7-12 years, completed a modified Sayers questionnaire before an orthodontic screening in a public health center in Finland. After completing the questionnaire, the participants underwent a clinical examination of the occlusion by an orthodontist specialist. A Spearman's rank correlation was conducted to evaluate the relationship between the questionnaire answers. The chi square statistic was applied to assess association between categorical variables.</p><p><strong>Results: </strong>From the initial orthodontic screening, a sample of 98, 94 participants were included in further analysis. Of them, 89% expressed a self-perceived need for orthodontic treatment. Orthodontic treatment need was determined by an orthodontist for 66% of the participants based on a severe malocclusion. Gender, age, or family history of orthodontic treatment were not associated with subjective treatment need. The main expectations for orthodontic treatment result were to straighten the teeth, to get a better smile, and to avoid problems in the future.</p><p><strong>Conclusions: </strong>The study found that patients' expectations of treatment did not fully align with reality. More information for patients and their guardians is needed in advance to avoid unrealistic expectations before the orthodontic treatment.</p>","PeriodicalId":7313,"journal":{"name":"Acta Odontologica Scandinavica","volume":"84 ","pages":"377-385"},"PeriodicalIF":1.4,"publicationDate":"2025-06-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144315756","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effect of occlusal reduction on post-operative pain of symptomatic and asymptomatic molar teeth.","authors":"Aysenur Kamacı Esen, Fatma Furuncuoğlu, Fatima Betul Basturk, Muhammet Nuri Taşcıoğlu, Masoud Parirokh","doi":"10.2340/aos.v84.43872","DOIUrl":"10.2340/aos.v84.43872","url":null,"abstract":"<p><strong>Objective: </strong>This study aimed to compare the intensity of post-operative pain after single-visit root canal treatment of symptomatic or asymptomatic teeth following occlusal reduction.</p><p><strong>Methods: </strong>A total of 140 symptomatic or asymptomatic patients in need of root canal therapy were registered in this prospective, single-centre, single-blind, randomised clinical trial. For all patients, root canal treatment was carried out in a single visit, and the teeth were restored using composite resin. The patients were randomly allocated into four treatment groups, two of which included occlusal reduction while two treatments left the occlusional contacts intact. Patients' pain were assessed using a 0-3 verbal rate scale 1, 3, and 7 days following root canal treatment. The pain incidence and intensity were compared using the chi-square and Fisher's exact tests.</p><p><strong>Results: </strong>Overall, the post-operative pain intensity was low. Symptomatic individuals had significantly more discomfort at day 1 post-operatively compared to asymptomatic patients (p < 0.008). The pain incidence significantly decreased over time for symptomatic patients. When compared to asymptomatic patients without occlusal reduction, symptomatic patients with occlusal reduction had a greater pain incidence at day 3 (p < 0.011). For other time intervals, no significant differences in post-operative pain incidence or intensity were found.</p><p><strong>Conclusion: </strong>Single-visit root canal treatments involving occlusal reduction in both symptomatic or asymptomatic molars had no significant effect on post-operative pain.</p>","PeriodicalId":7313,"journal":{"name":"Acta Odontologica Scandinavica","volume":"84 ","pages":"371-376"},"PeriodicalIF":1.4,"publicationDate":"2025-06-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12186432/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144264964","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Manifestations of the oral mucosa and salivary glands in irritable bowel syndrome and microscopic colitis - A systematic review.","authors":"Hanna Göthlin, Bengt Hasséus, Klas Sjöberg, Maria Bankvall","doi":"10.2340/aos.v84.43870","DOIUrl":"10.2340/aos.v84.43870","url":null,"abstract":"<p><strong>Objective: </strong>There is a well-established association of oral manifestations in the non-infectious chronic diarrhoeal conditions namely, Morbus Crohn, ulcerative colitis, and coeliac disease. Such a connection may exist also for the remaining non-infectious chronic diarrhoeal conditions, that is irritable bowel syndrome (IBS) and microscopic colitis (MC).</p><p><strong>Materials and methods: </strong>A systematic search was performed in Scopus and PubMed, rendering a total of 710 articles to be screened. All articles were screened independently and assessed for eligibility reporting comorbidity between either IBS or MC, and oral symptoms/disease. Quality assessment and data extraction were performed.</p><p><strong>Results: </strong>In all, 17 articles were included. Sjögren's syndrome (SS) in patients with IBS ranged from 3% to 33% and for IBS in SS between 29% to 62%. Dry mouth, bad breath, and foul taste were overrepresented in these patients. The occurrence of SS in patients with MC ranged from 2% to 9%, and for MC in SS from 1% to 2%.</p><p><strong>Conclusions: </strong>An association between SS and IBS and MC, respectively, is plausible. Few articles have explored other oral manifestations. Therefore, no specific conclusions can be drawn. It is pivotal to further explore oral manifestations of these conditions bridging the gap between dental care and general medicine to optimise diagnostics, treatment strategies, and ultimately patient care.</p>","PeriodicalId":7313,"journal":{"name":"Acta Odontologica Scandinavica","volume":"84 ","pages":"349-362"},"PeriodicalIF":1.4,"publicationDate":"2025-06-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12186438/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144264966","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}