Acta Odontologica Scandinavica最新文献

{"title":"Implant treatment modalities of non-syndromic congenitally missing premolars: a retrospective case series of 74 specialist care patients over an 11-year-cohort.","authors":"Sarwat Jabeen Hassan, Olli-Pekka Lappalainen, Ojala-Alasuutari Marleena, Virpi Harila, Ritva Näpänkangas","doi":"10.2340/aos.v84.44657","DOIUrl":"10.2340/aos.v84.44657","url":null,"abstract":"<p><strong>Objective: </strong>The study aims to evaluate the course of implant treatment for congenitally missing lower -second premolars in patients referred to publicly funded specialist care over an 11-year period.</p><p><strong>Material and methods: </strong>This retrospective, register-based cohort study selected patient data on dental implant treatment in the lower second premolar region from 2009 to 2019 (n = 146). After applying exclusion criteria, the final sample included 74 patients. Data on retained deciduous teeth, orthodontic treatment prior to implant placement, and implantation procedures were gathered from patient files. Results were presented using descriptive statistics, t-test, and Chi-square analyses (p < 0.05).</p><p><strong>Results: </strong>The most common orthodontic treatment was space optimization before dental implant placement. Most retained deciduous teeth were extracted between ages 21 and 29, with a median of 6 months before implant placement. Bone grafting was performed at 23% of implant sites. The mean implant diameter was 4.0 mm, and the mean implant length was 9.6 mm. Good primary stability was achieved in all cases.</p><p><strong>Conclusion: </strong>Individually planned orthodontic and surgical treatments are essential in managing congenitally missing lower premolars, particularly when implant placement is indicated. Early diagnosis and collaboration between dental specialists are key elements in the treatment. A multidisciplinary approach ensures optimal space for implant, bone preservation, and optimal implant alignment.</p>","PeriodicalId":7313,"journal":{"name":"Acta Odontologica Scandinavica","volume":"84 ","pages":"528-534"},"PeriodicalIF":1.9,"publicationDate":"2025-09-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12421332/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144991062","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Evaluation of mandibular bone abnormalities in patients with chronic kidney disease using cone beam computed tomography: A retrospective study.","authors":"Heelim Lee, Jae Suk Jung, Jiwoo Lee, Seung Il Song, Jeong Keun Lee, Ji Min Kim, Bumhee Park, Inwhee Park, Suk Ji","doi":"10.2340/aos.v84.44619","DOIUrl":"10.2340/aos.v84.44619","url":null,"abstract":"<p><strong>Objective: </strong>This study evaluated mandibular cortical thickness and morphological changes in chronic kidney disease (CKD) patients using cone beam computed tomography (CBCT) and their correlation with bone metabolism markers.</p><p><strong>Methods: </strong>CKD patients were divided into CKD-I (eGFR (estimated glomerular filtration rate) < 30) and CKD-II (eGFR ≥ 30) groups, with healthy controls for comparison. Mental index (MI), antegonial index (AI), and panoramic mandibular index (PMI) were compared using Kruskal-Wallis test. Mandibular cortical index (MCI) classifications, lamina dura loss, and soft tissue calcifications were assessed using Fisher's test. Relationships between serum bone metabolism markers and radiomorphometric indices were analyzed by linear regression.</p><p><strong>Results: </strong>The study included 94 CKD patients (56 CKD-I, 38 CKD-II) and 88 controls. MI and AI were significantly lower in CKD-I versus controls (p < 0.05). MCI class I was less prevalent in CKD-I (5.4%) than controls (35.2%) (p < 0.001). Lamina dura loss (p = 0.006) and soft tissue calcifications (p = 0.009) occurred more frequently in CKD groups. Elevated alkaline phosphatase was associated with reduced cortical thickness (p < 0.01).</p><p><strong>Conclusions: </strong>Although findings should be interpreted considering the retrospective design's limitations, CBCT revealed significant bone abnormalities in CKD patients, with compromised bone quality and reduced mandibular cortical thickness, especially in advanced renal impairment, suggesting its value for pre-implant bone quality assessment in CKD patients.</p>","PeriodicalId":7313,"journal":{"name":"Acta Odontologica Scandinavica","volume":"84 ","pages":"517-526"},"PeriodicalIF":1.9,"publicationDate":"2025-09-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12416334/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144938596","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Correction of author list for article: A retrospective study analysing outcomes of the coronectomy procedure at a university dental teaching clinic in Norway.","authors":"Umar Sharif, Johannes Finne, Nourhanim Fadul, Stein Atle Lie, Cecilie Gudveig Gjerde","doi":"10.2340/aos.v84.44706","DOIUrl":"https://doi.org/10.2340/aos.v84.44706","url":null,"abstract":"","PeriodicalId":7313,"journal":{"name":"Acta Odontologica Scandinavica","volume":"84 ","pages":"527"},"PeriodicalIF":1.9,"publicationDate":"2025-09-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144999396","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Awareness of erosive tooth wear and the consumption of acidic beverages among a group of Finnish adolescents.","authors":"Elisa Lind, Auli Suominen, Vuokko Loimaranta, Marja Pöllänen, Merja Laine","doi":"10.2340/aos.v84.44568","DOIUrl":"https://doi.org/10.2340/aos.v84.44568","url":null,"abstract":"<p><strong>Objective: </strong>Adolescents belong to the high-risk group of erosive tooth wear (ETW), but by contrast, they are reported to lack knowledge about this condition and its association with the intake of acidic beverages. This study aimed to survey the awareness of ETW and the consumption of beverages among a group of Finnish adolescents.</p><p><strong>Material and methods: </strong>A survey was conducted using an online questionnaire for the students in two upper comprehensive schools in the province of Southwest Finland. The awareness of ETW and the consumption frequencies of 14 beverages according to gender and school grade were analysed using chi-square or Fisher's exact test. The associations of the awareness of ETW with gender, school grade and acidic beverage consumption were analysed by logistic regression.</p><p><strong>Results: </strong>Most of the 230 respondents consumed acidic beverages more than once a week. The consumption of lemonades (OR [odds ratio] 2.79-3.05, p = 0.008-0.018, 95% CI 1.19-7.00) and energy drinks (OR 5.59, p = 0.0008, 95% CI 2.06-15.2) was more common among those who assumed that ETW is not preventable. However, 45-47% of the respondents have not received information about ETW or its prevention from dental care professionals.</p><p><strong>Conclusion: </strong>The studied Finnish adolescents have a lack of knowledge about ETW and the acidic beverage consumption among them requires intervention.</p>","PeriodicalId":7313,"journal":{"name":"Acta Odontologica Scandinavica","volume":"84 ","pages":"509-516"},"PeriodicalIF":1.9,"publicationDate":"2025-09-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144938658","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Poor oral health, related quality of life, and use of dental care system among vulnerable migrants in Denmark - a cross-sectional study.","authors":"Josefina Salazar, Hanne Winther Frederiksen, Hanne Nødgaard Christensen, Esben Boeskov Øzhayat","doi":"10.2340/aos.v84.44658","DOIUrl":"10.2340/aos.v84.44658","url":null,"abstract":"<p><strong>Objective: </strong>The study aims to describe the oral status, oral health-related quality of life (OHRQoL), and oral-health behaviours of vulnerable adult migrants with complex health problems.</p><p><strong>Methods: </strong>We conducted a descriptive cross-sectional study at the Section of Immigrant Medicine, Hvidovre Hospital, Denmark. We conducted clinical examinations to assess participants' number of teeth, caries, oral hygiene, and periodontal status. Participants also completed a questionnaire to evaluate OHRQoL, oral-health related behaviours (e.g. use of dental care system), and perceived barriers to access dental treatment and maintaining oral hygiene.</p><p><strong>Results: </strong>We included 50 participants, with a mean age of 49.4 (SD 7.4) years, 82% of whom were women, and 40% were from the Middle East and North Africa. Regarding oral status, 28% of participants had a full dentition, 54% had decayed teeth, 12% had good oral hygiene, and 46% had periodontal disease. Regarding OHRQoL, 92% of participants reported that their oral health negatively impacted one or more daily activities. Around 40% of participants had visited the dentist in Denmark the previous year, and 95% reported the costs as a barrier to dental care.</p><p><strong>Conclusions: </strong>There is a high prevalence of oral disease with a massive impact on the OHRQoL of this group of vulnerable migrants. Despite the need for essential dental treatments, participants rarely used the Danish dental care system. Our findings highlight the need for multi-sectoral interventions for this population.</p>","PeriodicalId":7313,"journal":{"name":"Acta Odontologica Scandinavica","volume":"84 ","pages":"501-508"},"PeriodicalIF":1.9,"publicationDate":"2025-09-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12409961/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144938627","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The three-dimensional influence and clinical significance of anterior traction with rapid expansion during dental replacement.","authors":"Naizheng Gou, Xiaoqin Wang, Haiyan Li, Zuoying Dong","doi":"10.2340/aos.v84.44580","DOIUrl":"https://doi.org/10.2340/aos.v84.44580","url":null,"abstract":"<p><strong>Objectives: </strong>This study aimed to investigate the effects of rapid maxillary expansion using a Hyrax-type appliance (RME-Hyrax) with anterior traction on the maxillary arch during mixed dentition and its clinical significance, focusing on changes in arch dimensions, occlusal stability, and masticatory function.</p><p><strong>Materials and methods: </strong>Forty-two patients with transverse maxillary deficiency were treated with RME-Hyrax, while an untreated control group of 40 received no treatment. Pre- and post-treatment dental casts were analyzed using a 3D scanner. Arch length, width, and occlusal stability were measured. Statistical analysis was performed using paired t-tests and linear regression.</p><p><strong>Results: </strong>RME significantly increased maxillary arch widths at all measured points: 3CW: +4.06 mm, 4CW: +4.88 mm, 5CW: +4.09 mm, 6MCW: +3.00 mm (all p  <  0.001). Mandibular arch widths similarly increased (3CW: +3.18 mm, 4CW: +4.00 mm, 5CW: +4.61 mm, 6MCW: +3.07 mm; all p  <  0.001). Buccal movement of first permanent molars was significant in both arches (maxillary: 1.61-1.78 mm, mandibular: 1.52-1.68 mm; all p  <  0.001). Occlusal stability improved clinically, evidenced by increased maximum bite area (+19.66 mm², exceeding the 15% threshold for functional gain; p  <  0.001) and force (+1.06 kg, surpassing the 0.5 kg minimum meaningful change; p  <  0.001), with reduced asymmetry index (-22.03%, p  <  0.001). Masticatory efficiency improved from 54.22 to 84.61% (Δ30.39%, < 25% threshold; p  <  0.001).</p><p><strong>Conclusions: </strong>Hyrax-type RME is effective for correcting transverse maxillary deficiencies, expanding both the maxillary and mandibular arches, and improving occlusal and masticatory function. Early intervention can significantly enhance dental and functional health.</p>","PeriodicalId":7313,"journal":{"name":"Acta Odontologica Scandinavica","volume":"84 ","pages":"491-500"},"PeriodicalIF":1.9,"publicationDate":"2025-08-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12398110/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144938639","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Regenerative potential of the intermediate filaments of albino rat parotid glands subjected to fractionated radiotherapy: an immunohistochemical analysis.","authors":"Sherif S Hassan, Ehab T Azab, Alaa W Alqutub, Mashael S Alqahtani, Abrar K Demyati, Abdullah A Holdar, Fatma M Alkassimi, Mahmoud A Attia, Reda A Nofal","doi":"10.2340/aos.v84.44182","DOIUrl":"https://doi.org/10.2340/aos.v84.44182","url":null,"abstract":"<p><strong>Objectives: </strong>Radiotherapy is a common treatment for head and neck malignancies; however, it frequently affects salivary glands, leading to xerostomia. This study evaluated the effects of radiotherapy on cytokeratin localization in the parotid gland, examining whether changes indicate recovery or progressive damage over a year.</p><p><strong>Methods: </strong>The study included eight control rats and 16 irradiated rats exposed to 30 Gy of radiation over 6 days. The experiment was conducted from January 2023 to April 2024. Subgroup IIa rats were sacrificed 1 month after radiation exposure, while subgroup IIb rats were sacrificed after 1 year. The parotid gland was prepared for histological and immunohistochemical analysis of intermediate filaments.</p><p><strong>Results: </strong>In the control parotid gland, immunohistochemical analysis revealed mild cytokeratin in ductal and serous cells. Subgroup IIa exhibited strong cytokeratin expression in the acini and duct cells, which was significantly different from the control group. One year after radiation, the cytokeratin of subgroup IIb was comparable to that of the control, with no significant difference.</p><p><strong>Conclusion: </strong>In subgroup IIa, cytokeratin staining was notably stronger in ductal and acinar cells, leading to disrupted distribution that impaired saliva production and transport. In subgroup IIb, the redistribution of cytokeratin exhibited distinct recovery patterns in ductal and acinar cells.</p>","PeriodicalId":7313,"journal":{"name":"Acta Odontologica Scandinavica","volume":"84 ","pages":"472-478"},"PeriodicalIF":1.9,"publicationDate":"2025-08-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12382380/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144938604","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Advanced glycation end products induce inflammaging in periodontal ligament fibroblasts through RAGE/AKT/mTOR/glycolysis pathway.","authors":"Lin Xiong, Jiayu Shu, Hongli Gao, Yufeng Qin, Yuehan Zhang, Xuelian Chang, Qiang Dong, Helin Chen","doi":"10.2340/aos.v84.44581","DOIUrl":"https://doi.org/10.2340/aos.v84.44581","url":null,"abstract":"<p><strong>Background: </strong>Inflammaging plays a pivotal role in the pathogenesis of multiple age-related diseases, including periodontitis. Advanced glycation end products (AGEs) are known to induce inflammaging and exacerbate periodontitis. However, the mechanisms by which AGEs promote inflammaging remain unclear. This study aimed to investigate the mechanisms underlying AGE-induced inflammaging.</p><p><strong>Methods and results: </strong>Human periodontal ligament fibroblasts (hPDLFs) were extracted and stimulated with lipopolysaccharide (LPS), with prior treatment using AGEs. The expression of pro-inflammatory cytokines was measured to explore the role of AGEs in LPS-induced inflammation. Subsequently, hPDLFs were treated with AGEs and pre-incubated with 2-deoxyglucose (2-DG, a glycolysis inhibitor), Ly294002 (an AKT/mTOR pathway inhibitor), and FPS-ZM1 (a receptor for advanced glycation end product [RAGE] antagonist) to assess the levels of inflammaging markers, glycolysis, AKT/mTOR pathway activation, and RAGE expression, along with the potential relationships among these factors. Our findings demonstrated that AGEs significantly increased the expression of pro-inflammatory cytokines in response to LPS stimulation. Additionally, AGEs alone elevated the levels of inflammaging factors, including cell senescence, senescence-associated secretory phenotype factors, SA-β-Gal expression, glycolysis markers, and AKT/mTOR pathway activation. Furthermore, inhibiting glycolysis reduced AGE-induced inflammaging, while blocking the AKT/mTOR pathway, suppressed both AGE-induced inflammaging and glycolysis. Antagonizing RAGE effectively blocked AGE-induced inflammaging, glycolysis, and AKT/mTOR pathway activation.</p><p><strong>Conclusions: </strong>Our study indicated that AGE-induced inflammaging through binding to RAGE to activate the AKT/mTOR pathway and eventually enhancing glycolysis level, which may contribute to the increased inflammatory response triggered by LPS. These findings suggest that inflammaging is a critical mechanism through which AGEs exacerbate periodontitis.</p>","PeriodicalId":7313,"journal":{"name":"Acta Odontologica Scandinavica","volume":"84 ","pages":"479-490"},"PeriodicalIF":1.9,"publicationDate":"2025-08-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12382382/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144938602","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Laypersons' esthetic assessment of teeth with de- or hypomineralization - a web-based survey.","authors":"Laura Ståhl, Nina Sabel, Julia Naoumova","doi":"10.2340/aos.v84.44231","DOIUrl":"10.2340/aos.v84.44231","url":null,"abstract":"<p><strong>Objective: </strong>To investigate young individuals' esthetic perception of color on the buccal surface of maxillary anterior teeth, self-perception of own tooth color, and general dental esthetic estimates by using a web-based survey.</p><p><strong>Methods: </strong>A digital questionnaire was advertised on social media in 2024, targeting 18-30-year-olds in Sweden. The questionnaire included attitudes toward own tooth color, cases with molar incisor hypomineralization (MIH), fluorosis (F), white spot lesions (WSL), and general dental esthetic estimates. Chi2 assessed differences between groups, and the independent sample T-test calculated mean differences in responses. Statistical significance was set at p < 0.05.</p><p><strong>Results: </strong>Out of 2,082 respondents (55% women, 43% men, mean age 25.1 years), 77% rated their tooth color as acceptable, with no gender or age differences (p > 0.05). Pigmented fluorosis was rated as nonacceptable by 94% of the respondents, followed by cases with WSLs. At least 90% cited deviant color on a part of a tooth (DCP) as a reason for nonacceptance. Even tooth color (mean, standard deviation [SD]: 8.02, 2.36) was rated more important than white teeth (mean, SD: 7.25, 2.04), p < 0.001.</p><p><strong>Conclusion: </strong>De- and hypomineralization on maxillary anterior teeth are perceived negatively by young individuals in terms of dental esthetics. An even tooth color was valued higher than white teeth.</p>","PeriodicalId":7313,"journal":{"name":"Acta Odontologica Scandinavica","volume":"84 ","pages":"446-456"},"PeriodicalIF":1.9,"publicationDate":"2025-08-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144870844","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Retraction of article: Effectiveness and safety of Bifidobacterium in preventing dental caries: a systematic review and meta-analysis.","authors":"Yan Wang, Jiahe Wang, Siyuan Hao","doi":"10.2340/aos.v84.43064","DOIUrl":"10.2340/aos.v84.43064","url":null,"abstract":"<p><p>N/A.</p>","PeriodicalId":7313,"journal":{"name":"Acta Odontologica Scandinavica","volume":"84 ","pages":"471"},"PeriodicalIF":1.9,"publicationDate":"2025-08-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12398101/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145013722","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}