Acta Odontologica Scandinavica最新文献

筛选
英文 中文
E-cadherin expression in the tongue epithelium of streptozotocin-induced diabetic rats: an exploratory study. 链脲佐菌素诱导的糖尿病大鼠舌上皮中e -钙粘蛋白表达的探索性研究。
IF 1.4 4区 医学
Acta Odontologica Scandinavica Pub Date : 2025-05-13 DOI: 10.2340/aos.v84.43564
Hassan Hamed Kaabi, Abdullah Mohamed Alsoghier, Islam Abdulrahim Alredah, Rayan Mohammed Alqahtani, Ibrahim Suliman Alsanie, Hanan Abdulgafour Balto
{"title":"E-cadherin expression in the tongue epithelium of streptozotocin-induced diabetic rats: an exploratory study.","authors":"Hassan Hamed Kaabi, Abdullah Mohamed Alsoghier, Islam Abdulrahim Alredah, Rayan Mohammed Alqahtani, Ibrahim Suliman Alsanie, Hanan Abdulgafour Balto","doi":"10.2340/aos.v84.43564","DOIUrl":"https://doi.org/10.2340/aos.v84.43564","url":null,"abstract":"<p><strong>Objective: </strong>Little was found on the association between diabetes and its effect on epithelial intercellular adhesion. However, no study reported the association between hyperglycemia and E-cadherin-mediated cell adhesion in tongue epithelium. This study aimed to explore the potential impacts of hyperglycemia on the epithelial E-cadherin expression in the tongue's epithelial tissue in streptozotocin (STZ)-induced diabetic rats.</p><p><strong>Material and methods: </strong>Twelve male Wistar albino rats were randomly allocated into control and STZ-induced diabetic groups. At the 5-week post-STZ injection, rats were euthanized, and the tongues were harvested and preserved in formalin. Epithelial thickness was assessed using hematoxylin and eosin (H&E) staining, while immunohistochemistry (IHC) was employed to analyze the expression of E-cadherin. Statistical analysis was performed using unpaired t-tests and two-proportion Z-tests, with a significance level determined at p < 0.05.</p><p><strong>Results: </strong>The results showed a significant reduction in epithelial thickness in the dorsal tongue of STZ-diabetic rats compared to the control group (p = 0.0173). Additionally, E-cadherin expression in the dorsal tongue epithelium was markedly weaker in the diabetic group than in the control (p < 0.0001).</p><p><strong>Conclusions: </strong>This exploratory study is the first to report that hyperglycemia reduces E-cadherin expression in the dorsal tongue epithelium, possibly contributing to oral epithelial alterations observed in diabetes. These findings not only highlight the potential diagnostic value of E-cadherin as a biomarker for oral complications in diabetic patients but also provide a foundation for future translational and clinical studies exploring therapeutic interventions targeting epithelial integrity in diabetes.</p>","PeriodicalId":7313,"journal":{"name":"Acta Odontologica Scandinavica","volume":"84 ","pages":"226-231"},"PeriodicalIF":1.4,"publicationDate":"2025-05-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143952805","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
A questionnaire-based survey of COVID-19 transmission in dental practice during the pandemic: comparison between the 1st-5th and the 6th-8th surges in Japan. 基于问卷的大流行期间牙科诊所COVID-19传播调查:日本第1 -5次与第6 -8次高峰的比较
IF 1.4 4区 医学
Acta Odontologica Scandinavica Pub Date : 2025-05-13 DOI: 10.2340/aos.v84.43420
Hironori Sakai, Eiji Kondo, Hirokazu Tanaka, Akinobu Shibata, Shizuka Nakatani, Hiroshi Kurita
{"title":"A questionnaire-based survey of COVID-19 transmission in dental practice during the pandemic: comparison between the 1st-5th and the 6th-8th surges in Japan.","authors":"Hironori Sakai, Eiji Kondo, Hirokazu Tanaka, Akinobu Shibata, Shizuka Nakatani, Hiroshi Kurita","doi":"10.2340/aos.v84.43420","DOIUrl":"https://doi.org/10.2340/aos.v84.43420","url":null,"abstract":"<p><strong>Objectives: </strong>A previous questionnaire survey on infection control measures and infection status among practicing dentists during the 1st-5th surge of coronavirus disease 2019 (COVID-19) cases in Japan indicated a low risk of COVID-19 infection spreading through dental care. However, the low number of infected patients during the survey period may have been a contributing factor, and a sharp increase in the number of infected patients was subsequently observed. We re-examined the spread of infections in dental care settings and compared the results with those of previous reports.</p><p><strong>Materials and methods: </strong>An online questionnaire-based survey was administered in March 2023 to examine the situation from February 2022 to March 2023, when the 6th-8th surge of COVID-19 infection was observed in Japan. The survey was conducted via an online platform (Google Forms; San Mateo, California, USA). The call for participation was publicized to members of the Nagano Dental Association. The survey consisted of questions on clinical activities, infection control measures, and confirmed or probable COVID-19 cases among patients and clinical staff.</p><p><strong>Results: </strong>The number of COVID-19-positive patients increased approximately 50-fold between the study periods. There was a 3.5-fold increase in the rate of dental treatment for infected patients.</p><p><strong>Conclusion: </strong>Even with the increased likelihood of contact with COVID-19 patients, no cases of infection during dental treatment were observed. The results of this study indicate that even with the possibility of contact with COVID-19 during dental treatment, the likelihood of COVID-19 clusters occurring in dental practices is low if appropriate infection prevention measures are in place.</p>","PeriodicalId":7313,"journal":{"name":"Acta Odontologica Scandinavica","volume":"84 ","pages":"212-217"},"PeriodicalIF":1.4,"publicationDate":"2025-05-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143961971","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Quality of life among adults with less severe malocclusions seeking orthodontic treatment. 寻求正畸治疗的轻度错颌成人的生活质量。
IF 1.4 4区 医学
Acta Odontologica Scandinavica Pub Date : 2025-05-13 DOI: 10.2340/aos.v84.43536
Narmina Sandlund, Idil Burt, Robert Schibbye
{"title":"Quality of life among adults with less severe malocclusions seeking orthodontic treatment.","authors":"Narmina Sandlund, Idil Burt, Robert Schibbye","doi":"10.2340/aos.v84.43536","DOIUrl":"https://doi.org/10.2340/aos.v84.43536","url":null,"abstract":"<p><strong>Objective: </strong>Severe malocclusions affect Oral Health Related Quality of Life (OHRQoL), but the effects of less severe malocclusions are underexplored. This study investigates OHRQoL and psychological well-being in adults with less severe malocclusion, but high subjective need of orthodontic treatment.</p><p><strong>Material and methods: </strong>This cross-sectional study included 130 study participants aged 18-75 years, with less severe malocclusion. Two groups were assessed: 65 with high subjective orthodontic treatment need and 65 in a control group. Patients with malocclusions graded with Index of Orthodontic Treatment Need-Dental Health Component (IOTN-DHC) index 1, 2, or 3 were included. Three questionnaires were used: Oral Health Impact Profile (OHIP-14), Hospital Anxiety and Depression Scale (HADS), and a general appearance perception survey.</p><p><strong>Results: </strong>The high subjective need group showed significantly higher OHIP-14 scores, reflecting poorer OHRQoL, compared to the control group. When age was considered, only the orofacial appearance subscale remained significant. No clinical signs of depression or anxiety were found among participants. However, a subset in the high subjective need group spent over an hour daily on their oral appearance.</p><p><strong>Conclusions: </strong>Adults seeking orthodontic treatment despite low objective treatment need may have impacted OHRQoL and an impairment from the time spent on their oral appearance. Dentist should consider patients' subjective treatment needs and impact on daily functioning when treating patients with mild malocclusions.</p>","PeriodicalId":7313,"journal":{"name":"Acta Odontologica Scandinavica","volume":"84 ","pages":"251-257"},"PeriodicalIF":1.4,"publicationDate":"2025-05-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143970348","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Efficacy of nonsurgical periodontal treatment on patients with periodontitis and type 2 diabetes mellitus: a systematic review and Bayesian network meta-analysis. 非手术牙周治疗对2型糖尿病合并牙周炎患者的疗效:一项系统综述和贝叶斯网络meta分析。
IF 1.4 4区 医学
Acta Odontologica Scandinavica Pub Date : 2025-05-13 DOI: 10.2340/aos.v84.43344
Xuejie Xie, Jun Xu, Yiming Li, Li Tang, Gulinuer Awuti
{"title":"Efficacy of nonsurgical periodontal treatment on patients with periodontitis and type 2 diabetes mellitus: a systematic review and Bayesian network meta-analysis.","authors":"Xuejie Xie, Jun Xu, Yiming Li, Li Tang, Gulinuer Awuti","doi":"10.2340/aos.v84.43344","DOIUrl":"https://doi.org/10.2340/aos.v84.43344","url":null,"abstract":"<p><strong>Objective: </strong>This study aimed to evaluate the effects of periodontal basic therapy combined with various adjunctive treatments on periodontal inflammation and glycemic control in patients with periodontitis and type 2 diabetes mellitus (T2DM) using network meta-analysis.</p><p><strong>Methods: </strong>Randomized controlled trials (RCTs) involving patients with periodontitis and T2DM were retrieved from PubMed, Embase, Cochrane Library, and Web of Science up to February 29, 2024. The Cochrane quality scoring system was applied to assess study quality, and data were analyzed using R and Stata. The study was registered in PROSPERO (Registration No.: CRD42024501722).</p><p><strong>Results: </strong>Thirty-seven RCTs involving 1,989 patients were included. Among the adjunctive therapies, scaling and root planing (SRP) with local satranidazole gel (SZ) achieved the best improvement in probing depth (PD) and clinical attachment level (CAL); SRP with systemic amoxicillin (AMX) significantly improved bleeding on probing (BOP); SRP with systemic doxycycline (Doxy) or antimicrobial photodynamic therapy (aPDT) was most effective for reducing glycated hemoglobin (HbA1c%); and SRP with diode laser (DL) improved fasting blood sugar (FBS) most effectively.</p><p><strong>Conclusion: </strong>SRP combined with local SZ may improve PD and CAL in patients with periodontitis and T2DM. Systemic AMX may enhance BOP outcomes, while DOXY or aPDT may help reduce HbA1c. DL may contribute to better FBS improvement.</p>","PeriodicalId":7313,"journal":{"name":"Acta Odontologica Scandinavica","volume":"84 ","pages":"201-211"},"PeriodicalIF":1.4,"publicationDate":"2025-05-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143970347","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Is the presence of accessory mandibular canals associated with the dimensions of the mandibular canal? 下颌副管的存在与下颌管的大小有关吗?
IF 1.4 4区 医学
Acta Odontologica Scandinavica Pub Date : 2025-05-13 DOI: 10.2340/aos.v84.43600
Emre Sözen, Hasan Akpınar
{"title":"Is the presence of accessory mandibular canals associated with the dimensions of the mandibular canal?","authors":"Emre Sözen, Hasan Akpınar","doi":"10.2340/aos.v84.43600","DOIUrl":"https://doi.org/10.2340/aos.v84.43600","url":null,"abstract":"<p><strong>Aim: </strong>The aim of this study is to classify accessory mandibular canals (AMC) and investigate their association with the dimensions of the mandibular canal (MC) to enhance surgical planning and prevent complications in dental treatments.</p><p><strong>Methods: </strong>Cone-beam computed tomography (CBCT) images were evaluated. AMC's frequency, length, and diameter, including dental, superior, inferior, forward-open, forward-closed, and retromolar types, were determined. Additionally, the dimensions of the MC, including its length and diameter, were measured, and the relationship between the AMC and MC was statistically analyzed. Descriptive statistics, chi-square test, independent samples t-test (for normally distributed data), Kruskal-Wallis test (for non-normally distributed data), and Tamhane post hoc test were used for statistical analysis of the data.</p><p><strong>Results: </strong>AMC was identified in 82 of the 222 hemimandibles examined (36.9%). It was found that the length and diameter of AMCs varied significantly depending on the AMC type (p = 0.000). The diameter of the dental type AMCs (mean 0.40 ± 0.22 mm) was considerably smaller than that of other AMC types (mean 0.86 ± 0.37 mm). The length and diameter of the MC were measured as 69.20 ± 5.10 mm and 2.96 ± 0.57 mm, respectively. While MC length was not found to influence the presence of AMC (p = 0.785), MC diameter was significantly associated with the occurrence of AMC (p = 0.000).</p><p><strong>Conclusions: </strong>AMC, which is critical for improving surgical planning and reducing the risk of complications in dental procedures, is not uncommon. Their presence should be carefully evaluated, particularly in cases where the MC has a larger diameter.</p>","PeriodicalId":7313,"journal":{"name":"Acta Odontologica Scandinavica","volume":"84 ","pages":"241-249"},"PeriodicalIF":1.4,"publicationDate":"2025-05-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143958123","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Comments on oral lesions and disorders and their prevalence arising from the use of illicit drugs in a prison population. 关于监狱人口中因使用非法药物而引起的口腔病变和紊乱及其流行情况的评论。
IF 1.4 4区 医学
Acta Odontologica Scandinavica Pub Date : 2025-05-13 DOI: 10.2340/aos.v84.43601
Manas Bajpai
{"title":"Comments on oral lesions and disorders and their prevalence arising from the use of illicit drugs in a prison population.","authors":"Manas Bajpai","doi":"10.2340/aos.v84.43601","DOIUrl":"https://doi.org/10.2340/aos.v84.43601","url":null,"abstract":"","PeriodicalId":7313,"journal":{"name":"Acta Odontologica Scandinavica","volume":"84 ","pages":"250"},"PeriodicalIF":1.4,"publicationDate":"2025-05-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144075279","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Association between subjective orthodontic treatment need, oral health-related quality of life, and occlusal deviations in a cohort of 17-year-old adolescents in Finland. 芬兰一组17岁青少年主观正畸治疗需求、口腔健康相关生活质量和咬合偏差之间的关系
IF 1.4 4区 医学
Acta Odontologica Scandinavica Pub Date : 2025-05-13 DOI: 10.2340/aos.v84.43565
Heidi Arponen, Eija Latvakoski, Linnea Närhi, Anna-Sofia Silvola
{"title":"Association between subjective orthodontic treatment need, oral health-related quality of life, and occlusal deviations in a cohort of 17-year-old adolescents in Finland.","authors":"Heidi Arponen, Eija Latvakoski, Linnea Närhi, Anna-Sofia Silvola","doi":"10.2340/aos.v84.43565","DOIUrl":"https://doi.org/10.2340/aos.v84.43565","url":null,"abstract":"<p><strong>Objective: </strong>To investigate the relationship between self-perceived orthodontic treatment need, satisfaction with dental esthetics and occlusion, oral health-related quality of life (OHRQoL), occlusal deviations, and orthodontic treatment history of 17-year-olds.</p><p><strong>Material and methods: </strong>Clinical examination and standardized questionnaire were completed by 108 adolescents from two municipal clinics. OHRQoL was measured with the Oral Health Impact Profile (OHIP-14) and malocclusion severity using the Peer Assessment Rating (PAR) Index. Associations between the variables were analyzed with Spearman's rank correlation and linear regression.</p><p><strong>Results: </strong>Of the participants, 55% had either undergone orthodontic treatment or were in treatment. The level of self-perceived treatment need was low and satisfaction with esthetics and functionality of occlusion high. Painful aching in the mouth was the most reported OHIP item, followed by self-consciousness. Subjective treatment need and PAR correlated positively (rs(95) = 0.389, p < 0.001), whereas the OHIP score and PAR score showed no association. Subjective treatment need, satisfaction, or treatment history did not predict the OHIP score.</p><p><strong>Conclusions: </strong>Majority of the adolescents were satisfied with their dental esthetics and occlusal function irrespective of past orthodontic treatment history. OHRQoL was poorer in adolescents with subjective orthodontic treatment need. Those with the greatest subjective treatment need had the most severe malocclusion.</p>","PeriodicalId":7313,"journal":{"name":"Acta Odontologica Scandinavica","volume":"84 ","pages":"232-240"},"PeriodicalIF":1.4,"publicationDate":"2025-05-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143959735","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Plasma levels of immune system activation markers Neopterin and Kynurenine-to-Tryptophan Ratio, and oral health among community-dwelling adults in Norway: a population-based, cohort study. 免疫系统激活标志物新蝶呤和犬尿氨酸与色氨酸比的血浆水平与挪威社区居住成年人的口腔健康:一项基于人群的队列研究
IF 1.4 4区 医学
Acta Odontologica Scandinavica Pub Date : 2025-05-13 DOI: 10.2340/aos.v84.43535
Sarala Banjara, Ellen Berggreen, Jannicke Igland, Anne-Kristine Åstrøm, Øivind Midttun, Dagmar Bunæs, Gerhard Sulo
{"title":"Plasma levels of immune system activation markers Neopterin and Kynurenine-to-Tryptophan Ratio, and oral health among community-dwelling adults in Norway: a population-based, cohort study.","authors":"Sarala Banjara, Ellen Berggreen, Jannicke Igland, Anne-Kristine Åstrøm, Øivind Midttun, Dagmar Bunæs, Gerhard Sulo","doi":"10.2340/aos.v84.43535","DOIUrl":"https://doi.org/10.2340/aos.v84.43535","url":null,"abstract":"<p><strong>Objective: </strong>Periodontitis is a condition characterised by inflammation. Neopterin and kynurenine-to-tryptophan ratio (KTR) are markers of immune system activation in response to inflammation whose elevated levels are linked to higher incidence and poorer prognosis of various systemic diseases. Their potential association with oral health remains underexplored. The aim of this study was to prospectively investigate the associations between these biomarkers and periodontal health status among community-dwelling adults in Hordaland County, Norway.</p><p><strong>Materials and methods: </strong>Neopterin and KTR were measured in 1,298 participants of the Hordaland Health Study, 1997-1999. Information on oral health indicators was obtained from the 'Hordaland-Oral Health Survey', 2020-2022. Ordinal logistic regression and negative binomial regression were used to explore the association between biomarkers and periodontitis, tooth loss, and current inflammation (extend of sites with pocket depth ≥4mm and bleeding on probing) and odds ratios (OR) and incidence rate ratios (IRR), along with respective 95% confidence intervals (CI) were reported.</p><p><strong>Results: </strong>No association was found between biomarker levels and periodontitis [neopterin: OR = 0.96, 95% CI: 0.69-1.33 for fourth (Q4) vs. first quartile (Q1); KTR: OR = 0.85, 95% CI: 0.61-1.18 for Q4 vs. Q1], tooth loss [neopterin: IRR = 1.00, 95% CI: 0.94-1.06 for Q4 vs. Q1; KTR: IRR = 0.97, 95% CI: 0.91-1.03 for Q4 vs. Q1) or extend of inflammation [neopterin: OR = 0.87, 95% CI: 0.70-1.09 for Q4 vs. Q1; KTR: OR = 0.98, 95% CI: 0.78-1.23 for Q4 vs. Q1].</p><p><strong>Conclusion: </strong>Plasma levels of neopterin and KTR were not prospectively associated with periodontal health and number of missing teeth.</p>","PeriodicalId":7313,"journal":{"name":"Acta Odontologica Scandinavica","volume":"84 ","pages":"218-225"},"PeriodicalIF":1.4,"publicationDate":"2025-05-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143959562","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Is there an association between superoxide dismutase gene polymorphisms, antioxidants in oxidative stress pathway, and oral health-related quality of life after root canal treatment? 超氧化物歧化酶基因多态性、氧化应激途径中的抗氧化剂与根管治疗后口腔健康相关生活质量之间是否存在关联?
IF 1.4 4区 医学
Acta Odontologica Scandinavica Pub Date : 2025-04-22 DOI: 10.2340/aos.v84.43426
Ludmila Da Silva Guimarães, Erlange Andrade Borges da Silva, Juliana Miranda Bonelli, Heitor Ganier Ribeiro, Alice Corrêa Silva-Sousa, Manoel Damião Sousa-Neto, Erika Calvano Küchler, Lívia Azeredo Alves Antunes, Fernanda Signorelli Calazans, Leonardo Santos Antunes
{"title":"Is there an association between superoxide dismutase gene polymorphisms, antioxidants in oxidative stress pathway, and oral health-related quality of life after root canal treatment?","authors":"Ludmila Da Silva Guimarães, Erlange Andrade Borges da Silva, Juliana Miranda Bonelli, Heitor Ganier Ribeiro, Alice Corrêa Silva-Sousa, Manoel Damião Sousa-Neto, Erika Calvano Küchler, Lívia Azeredo Alves Antunes, Fernanda Signorelli Calazans, Leonardo Santos Antunes","doi":"10.2340/aos.v84.43426","DOIUrl":"https://doi.org/10.2340/aos.v84.43426","url":null,"abstract":"<p><strong>Objective: </strong>To evaluate the association between genetic polymorphisms in SOD2 and SOD3 and oral health-related quality of life (OHRQoL).  Material and methods: The cohort study included 109 participants, all of whom underwent root canal treatment on a single-rooted maxillary or mandibular tooth with asymptomatic periapical periodontitis. The OHRQoL was assessed using the Oral Health Impact Profile-14 at three intervals: prior to root canal treatment (T0), 7 (T7), and 30 (T30) days post-treatment. Genomic DNA was extracted from buccal cells for genotyping of polymorphisms in SOD2 (rs5746136, rs4880, and rs10370) and SOD3 (rs2855262 and rs13306703) using real-time PCR. Both Univariate and Multivariate Poisson Regression analyses were conducted, with p < 0.05 indicating statistical significance.  Results: The rs2855262 polymorphism in the SOD3 gene showed a significant difference in the functional limitation domain in both codominant (p = 0.037) and recessive (p = 0.040) models. The rs13306703 polymorphism in SOD3 demonstrated a significant difference in physical pain [in codominant (p = 0.001) and recessive (p < 0.001) models], psychological discomfort [in codominant (p = 0.002) and recessive (p = 0.002) models], handicap [in codominant (p = 0.011) and dominant (p = 0.015) models], and total score [in codominant (p = 0.011) and recessive (p = 0.007) models]. In the Multivariate Poisson Regression analysis, SOD2 (rs5746136) was associated with the psychological disability domain [in codominant (p = 0.049) and recessive (p = 0.040) models] and SOD3 (rs13306703), in the handicap domain [in codominant (p = 0.028) and dominant (p = 0.037) models].  Conclusions: Genetic polymorphisms in SOD2 and SOD3 genes can influence the OHRQoL response in patients with asymptomatic periapical periodontitis.</p>","PeriodicalId":7313,"journal":{"name":"Acta Odontologica Scandinavica","volume":"84 ","pages":"191-200"},"PeriodicalIF":1.4,"publicationDate":"2025-04-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12056317/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143957908","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Changes in the electromyographic activity of masticatory muscles in patients undergoing bimaxillary surgery. 双颌手术患者咀嚼肌肌电图活动的变化。
IF 1.4 4区 医学
Acta Odontologica Scandinavica Pub Date : 2025-04-22 DOI: 10.2340/aos.v84.43408
Ali Kağan Özen, İsmail Ceylan
{"title":"Changes in the electromyographic activity of masticatory muscles in patients undergoing bimaxillary surgery.","authors":"Ali Kağan Özen, İsmail Ceylan","doi":"10.2340/aos.v84.43408","DOIUrl":"https://doi.org/10.2340/aos.v84.43408","url":null,"abstract":"<p><strong>Objective: </strong>The aim of this study is to investigate short-term changes in the electromyographic (EMG) activity of masticatory muscles in individuals with skeletal Class III malocclusion undergo double-jaw orthognathic surgery.</p><p><strong>Material and methods: </strong>In patients with skeletal Class III anomaly, EMG activity changes in the anterior temporalis and masseter muscles were measured before T0 and at 3 (T1) and 6 (T2) months after bimaxillary orthognathic surgery. Recordings were obtained using the 'MP100' device and circular Ag-AgCl electrodes during closure, clenching, chewing and swallowing. Data from 26 individuals (12 males, 14 females) with a mean age of 21.7 years were analysed using the Friedman test.</p><p><strong>Results: </strong>A significant decrease was observed in the right/left masseter muscles during clenching/chewing from T1 to T0 (right and left masseter clenching: p < 0.001, left masseter chewing: p < 0.01, right masseter chewing: p < 0.05), while a significant increase was noted in the right masseter's clenching function from T2 to T1 (p < 0.01). The EMG activity of the right anterior temporal muscle decreased during clenching at T1-T0 (p < 0.001), increased at T2-T1 (p < 0.05), and decreased during chewing/swallowing at T1-T0 (chewing: p < 0.001, swallowing: p < 0.05) and T2-T0 (p < 0.05). The left anterior temporal muscle showed decreased EMG activity during clenching at T1-T0 (p < 0.001), increased at T2-T1 (p < 0.05), and decreased during chewing at T1-T0 (p < 0.001). During swallowing, a decrease was observed at T2-T0 (p < 0.001).</p><p><strong>Conclusions: </strong>Partial changes in EMG activity were observed during some functions in the 3-month period; however, no significant overall change was recorded in the 6-month period.</p>","PeriodicalId":7313,"journal":{"name":"Acta Odontologica Scandinavica","volume":"84 ","pages":"182-190"},"PeriodicalIF":1.4,"publicationDate":"2025-04-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12056318/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144058282","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
0
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
确定
请完成安全验证×
相关产品
×
本文献相关产品
联系我们:info@booksci.cn Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。 Copyright © 2023 布克学术 All rights reserved.
京ICP备2023020795号-1
ghs 京公网安备 11010802042870号
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术官方微信