Joey Lam, A. Williamson, Zainab Salih, Megan Heere, J. Mindell
{"title":"Bedtime routines, development, and caregiver educational attainment in toddlerhood","authors":"Joey Lam, A. Williamson, Zainab Salih, Megan Heere, J. Mindell","doi":"10.3389/frsle.2023.1197297","DOIUrl":"https://doi.org/10.3389/frsle.2023.1197297","url":null,"abstract":"Implementing a consistent bedtime routine is an empirically supported intervention to improve sleep in toddlers, but little is known about its association with social-emotional outcomes, and among children living in lower socioeconomic status (SES) contexts.This study examined the longitudinal associations between bedtime routines, social-emotional development, and caregiver educational attainment in toddlers presenting to primary care.Caregivers of 40 toddlers (Mage = 12.85 months, 57.5% female, 62.5% Black/African American) completed questionnaires on sociodemographic factors and child bedtime routine consistency at their 12-month well visit. At the 15- and 24-month well visits, data were collected on child bedtime routine consistency and social-emotional development, including the Brief Infant-Toddler Social and Emotional Assessment (BITSEA) for social-emotional problems and competency and the Ages and Stages Questionnaire (3rd edition; ASQ-3) to assess communication and personal-social skills.Overall, the majority of families engaged in a consistent bedtime routine (≥5 nights/week) at all time points (63% at 12 months, 75% at 15 months, and 86% at 24 months). Controlling for concurrent bedtime routine consistency, toddlers with a more consistent bedtime routine at 12 months exhibited less dysregulation at age 15 months. Toddlers without a consistent bedtime routine at 15 months exhibited more externalizing and internalizing problems and dysregulation at 24 months. Furthermore, there was a significant interaction between bedtime routine consistency at 15 months and caregiver education for internalizing problems at 24 months, such that toddlers of caregivers with a high school education or less who lacked a consistent bedtime routine showed the most internalizing problems.Clinicians should consider recommending that families with toddlers incorporate a nightly bedtime routine not only to improve overall sleep health, but also to potentially optimize toddlers' positive social-emotional and behavioral trajectories, especially in families with lower educational attainment.","PeriodicalId":73106,"journal":{"name":"Frontiers in sleep","volume":"42 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-08-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"90519205","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"The role of the WatchPAT device in the diagnosis and management of obstructive sleep apnea","authors":"C. D. Campbell, I. Sulaiman","doi":"10.3389/frsle.2023.1148316","DOIUrl":"https://doi.org/10.3389/frsle.2023.1148316","url":null,"abstract":"Obstructive sleep apnea (OSA) is a common condition affecting an estimated 936 million individuals worldwide, leading to a considerable demand for diagnostic services. Polysomnography, the current gold standard for diagnosis, is resource intensive and inconvenient for patients and healthcare providers. The WatchPAT is an unobtrusive device for home OSA diagnosis. It utilizes peripheral arterial tomography in conjunction with heart rate, oximetry, actingraphy, and respiratory movements for the diagnosis of OSA. It has good correlation with polysomnography for OSA diagnosis and also reports sleep time and sleep staging. The WatchPAT device has reported sensitivities of 81–95%, specificities of 66–100%, positive predictive values of 79–96%, and negative predictive values of 92% for the determination of the apnea–hypopnea index (AHI). It has also been studied and its use validated in a variety of patient populations, including children, older adults, pregnant women, and those with comorbid medical conditions. The device has also been adopted for use in screening for cardiac arrhythmia and central sleep apnea, although neither use has become widespread. With the emergence of telemedicine and an increasing demand for sleep services, the WatchPAT device can be a useful aid in OSA diagnostics.","PeriodicalId":73106,"journal":{"name":"Frontiers in sleep","volume":"2015 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-08-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"73742439","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
A. Chung, Leone Farquharson, A. Gopalkrishnan, S. Honaker
{"title":"“Something is wrong!” A qualitative study of racial disparities in parental experiences of OSA detection in their child","authors":"A. Chung, Leone Farquharson, A. Gopalkrishnan, S. Honaker","doi":"10.3389/frsle.2023.1193539","DOIUrl":"https://doi.org/10.3389/frsle.2023.1193539","url":null,"abstract":"Approximately 3% of American children are affected by obstructive sleep apnea (OSA), yet Black children are 2–4 times more likely to experience OSA compared to White children. Little is known about parental experiences in detection, diagnosis, and treatment of OSA in their child, and how these experiences may differ by race. The study objective was to highlight convergent and divergent experiences between and across Black and White parents in the OSA detection process for their child.We conducted 27 semi-structured interviews with mothers whose child was referred for a diagnostic overnight polysomnogram (PSG) to assess for OSA. Parents described how their child was referred for a PSG and their perceptions and feelings throughout the detection process. Data were analyzed using a thematic descriptive approach. Frequency of themes were examined by race. Themes that were unique to one racial group were categorized as divergent, whereas themes described by individuals from both groups were categorized as convergent. Within the convergent themes, we examined the prevalence within each racial group, noting those that were more prevalent (>10% difference in prevalence) in one race or the other.The sample included 19 Black and 8 White mothers, who were 36 years old on average. Qualitative analysis yielded 21 themes across 5 categories that captured divergent and convergent experiences across Black and White mothers during the OSA detection process for their child. Divergent themes that were unique to Black mothers included It Takes a Village—Teacher, Misplaced Blame, Missing the Day/night Connection, Trust in Provider, and the belief that Snoring is Normal. Only one divergent theme among White parents emerged, worries about Dying in Ones Sleep. Additional convergent themes were identified that were more prevalent in one race compared to the other.Black and White mothers experienced different paths to detection and diagnosis for their child's sleep disordered breathing, that are affected by individual awareness, education, patient-provider interactions, and experiences with the healthcare system. Divergent themes such as Misplaced Blame among Black mothers were a potential indication of racism and health disparities.","PeriodicalId":73106,"journal":{"name":"Frontiers in sleep","volume":"16 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-08-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"77166309","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Maureen E. McQuillan, Ian C. Jones, Haneen F. Abu Mayyaleh, Shajna Khan, S. Honaker
{"title":"Health disparities in the detection and prevalence of pediatric obstructive sleep apnea","authors":"Maureen E. McQuillan, Ian C. Jones, Haneen F. Abu Mayyaleh, Shajna Khan, S. Honaker","doi":"10.3389/frsle.2023.1225808","DOIUrl":"https://doi.org/10.3389/frsle.2023.1225808","url":null,"abstract":"Pediatric Obstructive Sleep Apnea (OSA) is associated with negative health outcomes, behavior problems, and poor academic performance when left untreated. Prior research has shown that children from racial and ethnic minority backgrounds and those living in lower socioeconomic status (SES) homes or neighborhoods have higher prevalence of OSA but lower likelihood of receiving evidence-based care for OSA. Disparities in pediatric OSA detection (e.g., timely assessment and diagnosis) likely contribute to this observed inequity in receiving treatment. A polysomnogram (PSG) is the gold standard for diagnosing OSA but completing PSG can be challenging. Study aims were to examine racial, ethnic, and SES differences in (1) OSA prevalence and severity and (2) OSA detection, specifically PSG completion rates, timing since referral, and age of diagnosis.Children (aged 1–18, N = 1,860, 56% male) were referred for PSG during a 6-month period. Participants' racial/ethnic background were as follows: 64.8% White non-Hispanic, 23.5% Black non-Hispanic, 9.4% White Hispanic, and 2.4% other. Children predominantly had Medicaid insurance (64.5%). SES was measured by insurance type and neighborhood SES using the Distressed Communities Index (DCI) for each participant's zip code (Economic Innovations Group; https://eig.org/dc). Covariates included child age and sex, BMI, premature birth status, and smoke exposure in the home.We replicated previous research by showing that children from minority racial/ethnic backgrounds and lower SES backgrounds had higher prevalence rates of OSA and worse disease severity. Across racial, ethnic, and socioeconomic backgrounds, only 31.6% of the children referred successfully completed PSG. Insurance coverage (Medicaid or private vs. self-pay), was an important factor in predicting earlier timing and better completion rates of PSG, which is essential for successful diagnosis and treatment of pediatric OSA.","PeriodicalId":73106,"journal":{"name":"Frontiers in sleep","volume":"8 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-08-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"78492827","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
S. Mashaqi, Anas Rihawi, P. Rangan, K. Ho, Mateen Khokhar, Sonia Helmick, Y. Ashouri, D. Combs, Iman Ghaderi, S. Parthasarathy
{"title":"The impact of bariatric surgery on breathing-related polysomnography parameters—Updated systematic review and meta-analysis","authors":"S. Mashaqi, Anas Rihawi, P. Rangan, K. Ho, Mateen Khokhar, Sonia Helmick, Y. Ashouri, D. Combs, Iman Ghaderi, S. Parthasarathy","doi":"10.3389/frsle.2023.1212936","DOIUrl":"https://doi.org/10.3389/frsle.2023.1212936","url":null,"abstract":"We conducted this systematic review and meta-analysis (SRMA) to evaluate the impact of bariatric surgery on obstructive sleep apnea (OSA) as represented by the following polysomnography (PSG) parameters: apnea-hypopnea index (AHI), oxygen desaturation index (ODI), mean oxygen desaturation (mean SpO2), total sleep time spent with SpO2 < 90% (T-90), and the nadir of oxygen saturation (L SpO2).A comprehensive search of the literature was conducted in Ovid MEDLINE, Embase, and Scopus databases from inception to March 31, 2023. Only articles written in English were reviewed. The analysis of all outcomes was performed using a random-effects model. We included 30 studies (two randomized controlled trials and 28 observational studies) in the final quantitative synthesis with a total of 1,369 patients.We concluded that bariatric surgery (regardless of the type) was associated with reduction in AHI [MD 23.2 events/h (95%CI 19.7, 26.8)], ODI [MD 26.8 events/h (95%CI 21.6, 32.1)], mean SpO2 [MD−1.94% (95%CI −2.5, −1.4)], T-90 [MD 7.5min (95%CI 5.0, 10.0)], and L SpO2 [MD 9.0% (95%CI −11.8, −6.3)].Our SRMA results are updates to previously published results and continue to support the positive impact of bariatric surgery on OSA and sleep-related hypoxia.","PeriodicalId":73106,"journal":{"name":"Frontiers in sleep","volume":"25 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-08-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"81041366","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Sleep and happiness: socio-economic, population and cultural correlates of sleep duration and subjective well-being in 52 countries","authors":"T. Lajunen, E. Gaygısız, Wen Wang","doi":"10.3389/frsle.2023.1118384","DOIUrl":"https://doi.org/10.3389/frsle.2023.1118384","url":null,"abstract":"Getting enough sleep is one of the essential lifestyle factors influencing health and well-being. However, there are considerable differences between countries in how much people sleep on average. The present study investigated how socio-economic factors, population variables, and cultural value dimensions are related to sleep duration in a sample of 52 countries.The study design was ecological, i.e., the aggregate values for each country were obtained, and their correlations to national average sleep duration were analysed. The sleep duration estimates were based on Sleep Cycle Application (Sleep Cycle AB, Gothenburg, Sweden) data. The socio-economic variables included the economic health of a country (GDP per capita), how well a country is governed (governance quality measured with WGI), and the economic inequality (the gap between rich and poor measured with the Gini index) within a nation. The population variables included the urbanisation rate (proportion of people living in urbanised areas), life expectancy at birth, mean years of schooling among the population aged 25 years and older, median age of the population, and the prevalence of obesity (% of adults with BMI ≥ 30). The cultural value dimensions were measured with Hofstede's cultural value dimensions (power distance, individualism, masculinity, uncertainty avoidance, long-term orientation, and indulgence). The data were analysed by using zero-order correlations, partial correlations, and canonical correlation analyses.Results showed a relatively strong intercorrelation between the national average of sleep duration and national happiness, i.e., subjective well-being. Among the socio-economic variables, WGI had the strongest relationship to sleep, whereas among population variables, schooling and obesity had the strongest correlations with sleep. Zero-order correlations between sleep and power distance and individualism were statistically significant, whereas in the partial correlations, individualism and masculinity appeared as important factors. Canonical correlation analysis showed strong correlations between the well-being variables (sleep and happiness) and the socio-economic variables, well-being variables and population variables, and cultural values and well-being variables.The present study is an opening for a new line of research in which sleep is seen as an essential part of societal life and collective well-being.","PeriodicalId":73106,"journal":{"name":"Frontiers in sleep","volume":"97 ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-07-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"72544886","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Olivia Bruce, Sayedeh Fatemeh Sajjadi, B. Galland, J. Gross, G. Dainty
{"title":"Exercise and autism: exploring caregiver insights on exercise participation and sleep patterns in autistic children in Aotearoa New Zealand","authors":"Olivia Bruce, Sayedeh Fatemeh Sajjadi, B. Galland, J. Gross, G. Dainty","doi":"10.3389/frsle.2023.1132935","DOIUrl":"https://doi.org/10.3389/frsle.2023.1132935","url":null,"abstract":"Autistic children experience sleep disturbances at a higher rate than do neurotypical children. It has been argued that sleep disturbances negatively impact behavior, exacerbate learning difficulties, and decrease the quality of life among autistic children. Increasing exercise has been proposed to address sleep disturbances, however, little is known about how exercise might best be promoted for autistic children in Aotearoa New Zealand. Here, we explored caregivers' lived experiences of their autistic child's sleep disturbances and participation in exercise.Semi-structured interviews were conducted with 15 mothers of autistic children aged between 5 and 10. Mothers also completed the Sleep Disturbances Scale for Children (SDSC).Scores on the SDSC indicated that there was considerable variation in sleep disturbance severity. Eight themes were identified from the interviews: sleep disturbances, the impact of exercise on sleep, exercise activities, whānau involvement in exercise, barriers for participation in exercise, support for participation in exercise, sensory considerations for participation in exercise, and activities specifically for children with special needs.Our findings highlight how challenging sleep disturbances can be for autistic children and their families and how participation in exercise can be promoted to potentially minimize their negative impact.","PeriodicalId":73106,"journal":{"name":"Frontiers in sleep","volume":"177 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-07-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"85435947","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
T. Strasser, Inga Rothert, Thomas Heine, T. Peters
{"title":"AuReTim: an inexpensive and extensible open-source auditory psychomotor vigilance test","authors":"T. Strasser, Inga Rothert, Thomas Heine, T. Peters","doi":"10.3389/frsle.2023.1168209","DOIUrl":"https://doi.org/10.3389/frsle.2023.1168209","url":null,"abstract":"Within a large joint research project aiming for characterizing the nonvisual effects of light (NiviL), AuReTim, a low-cost and extensible open-source portable psychomotor vigilance test using auditory stimuli was developed, tailored for field testing. Currently, an unprepared simple reaction time and a go/no-go paradigm using acoustic stimuli are implemented. AuReTim is based on inexpensive hardware, e.g., its core is a Raspberry Pi leveraging a touch screen as input. Its software is developed in Java™ using open-source libraries, therefore providing connectivity with other research setups, e.g., EEG, and easy extensibility with other stimulus paradigms. A simulation study proved the precise timing of AuReTim with limits of agreement between −1.86 and 1.67 ms. AuReTim combines the mobility of tablet-based psychomotor vigilance tests with the usability of conventional computer-based tests, which is especially helpful in field studies. AuReTim was successfully applied to study the effects of different lighting on alertness and proved to be a valuable tool for studies using the central nervous activation level as an outcome measure.","PeriodicalId":73106,"journal":{"name":"Frontiers in sleep","volume":"14 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-07-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"83545192","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
P. Castellanos, P. Satashia, Mantavya Punj, P. Castillo, B. Colaco, B. Dredla, E. Festic, J. Kaplan, C. Ruoff, L. Speicher, K. Walsh, N. Werninck, Mingyuan Yin, C. Burger, V. Arunthari, Joseph Cheung
{"title":"Assessment of sleep quality and sleep disordered breathing among post-hospitalized patients with COVID-19","authors":"P. Castellanos, P. Satashia, Mantavya Punj, P. Castillo, B. Colaco, B. Dredla, E. Festic, J. Kaplan, C. Ruoff, L. Speicher, K. Walsh, N. Werninck, Mingyuan Yin, C. Burger, V. Arunthari, Joseph Cheung","doi":"10.3389/frsle.2023.1214036","DOIUrl":"https://doi.org/10.3389/frsle.2023.1214036","url":null,"abstract":"We conducted a cross-sectional study to identify the presence of sleep disturbance and sleep disordered breathing in post-hospitalized patients with COVID-19 compared to a cohort of patients with no prior COVID-19 infection.Patients who were discharged from Mayo Clinic after hospitalization for COVID-19 and who had no existing diagnosis of sleep apnea or other sleep disorders were recruited for this study as cases. Patients who never had COVID-19 infection, nor any existing diagnosis of sleep apnea or other sleep disorders, were recruited from outpatient clinics as controls. Participants completed Pittsburgh Sleep Quality Index, Epworth Sleepiness Scale, and Fatigue Severity Scale questionnaires, as well as a home sleep apnea test.Forty-seven COVID-19 cases and 46 controls completed questionnaires. Cases were significantly older, with a median age of 56.0 vs. controls (50.5) and were found to have slightly worse sleep quality, a higher degree of daytime sleepiness, and a slightly higher degree of fatigue. In terms of sleep disordered breathing, 39 cases and 40 controls completed the home sleep apnea test. Obstructive sleep apnea, defined by an AHI score of 5 or higher, was found in a remarkable 97.4% of cases vs. 72.5% in controls. Severity of OSA also trended higher in the case group. However, the difference in AHI was not significant after adjusting for age and BMI.Patients who were hospitalized with COVID-19 showed a very high prevalence of OSA. In addition, they had a slightly higher degree of sleep disturbance, daytime sleepiness, and fatigue when compared to controls. Our results suggest that sleep medicine assessment in patients who had COVID-19 requiring hospitalization is warranted.","PeriodicalId":73106,"journal":{"name":"Frontiers in sleep","volume":"4 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-07-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"84674358","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
T. Kendzerska, A. Malhotra, A. Gershon, M. Povitz, D. McIsaac, S. Aaron, G. Bryson, R. Talarico, Michael Godbout, P. Tanuseputro, F. Chung
{"title":"Association between opioid prescription profiles and adverse health outcomes in opioid users referred for sleep disorder assessment: a secondary analysis of health administrative data","authors":"T. Kendzerska, A. Malhotra, A. Gershon, M. Povitz, D. McIsaac, S. Aaron, G. Bryson, R. Talarico, Michael Godbout, P. Tanuseputro, F. Chung","doi":"10.3389/frsle.2023.1161857","DOIUrl":"https://doi.org/10.3389/frsle.2023.1161857","url":null,"abstract":"Information is needed to guide safe opioid prescribing in adults referred for a sleep disorder assessment. Previous studies have shown that individuals referred for a sleep disorder assessment have a higher likelihood of long-acting opioids and higher opioid dosages prescription than the general population, suggesting that these individuals are more at risk for opioid-related adverse health consequences.We included all adults who underwent a diagnostic sleep study (index date) in Ontario, Canada, between 2013 and 2016 (n = 300,663) and filled an opioid prescription overlapping the index date (n = 15,713). Through provincial health administrative databases, individuals were followed over time to assess the association between opioid use characteristics and 1-year all-cause mortality, hospitalizations and emergency department (ED) visits, and opioid-related hospitalizations and ED visits within extended follow-up to 2018.Controlling for covariates, chronic opioid use (vs. not) was significantly associated with increased hazards of all-cause mortality [adjusted hazard ratio(aHR): 1.84; 95% confidence interval (CI): 1.12–3.02], hospitalization (aHR: 1.14; 95% CI: 1.02–1.28) and ED visit (aHR: 1.09; 95% CI: 1.01–1.17). A higher opioid dosage [morphine equivalent daily dose (MED) >90 vs. ≤ 90 mg/day] was significantly associated with increased hazards of all-cause or opioid-related hospitalization (aHR: 1.13; 95% CI: 1.02–1.26 and aHR: 2.27; 95% CI: 1.53–3.37, respectively). Morphine or hydromorphone prescription (vs. oxycodone) was significantly associated with an increased hazard of all-cause hospitalization (aHR: 1.30; 1.07–1.59 and aHR: 1.43; 95% CI: 1.20–1.70, respectively). Hydromorphone or fentanyl prescription (vs. oxycodone) was significantly associated with an increased hazard of opioid-related ED visit and/or hospitalization (aHR: 2.28, 95% CI: 1.16–4.47 and aHR: 2.47, 95% CI: 1.16–5.26, respectively).Findings from this retrospective study may inform the safe prescribing of opioids in adults referred for a sleep disorder assessment.","PeriodicalId":73106,"journal":{"name":"Frontiers in sleep","volume":"4 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-07-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"89766440","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}