Frontiers in sleep最新文献

{"title":"The modulation of emotional memory consolidation by dream affect","authors":"Liëtte du Plessis, Gosia Lipinska","doi":"10.3389/frsle.2023.1239530","DOIUrl":"https://doi.org/10.3389/frsle.2023.1239530","url":null,"abstract":"Introduction Research in the field of cognitive neuroscience has focused on the role of sleep in various neurocognitive processes such as memory consolidation. However, an area that has not been adequately researched is the role of dreaming in this memory process. This study aimed to determine the relationship between affect experienced in dreams and emotional memory consolidation. Considering that REM dreams are laden with emotion and that emotion enhances memory, one possibility is that dream affect could also play a role in emotional memory consolidation. We hypothesised that greater dream-related affect would be associated with greater memory retention of emotional but not neutral information. Methods 126 healthy participants, aged 18–35, were recruited for the online study, of which 103 participants had valid data (female: n =73). On the night of the study, participants viewed a series of pictures from the South African Affective Picture System (SA-APS) in an online session. Afterwards, they verbally recalled as many pictures as possible. The following morning, they were asked to recall any dreams and rate the emotional intensity of their dreams. Participants then again verbally recalled all the pictures that they could remember from the previous night. Results Contrary to the prediction, dream-related affect, regardless of valence, did not predict memory consolidation of positive or negative information. Instead, increases in dream-related affect, and especially anxiety were predictive of better memory retention of all information. The findings also showed that an increase in negative affect in dreams predicted better memory retention of negative information. Discussion Our results suggest that dream affect is an important modulator of memory consolidation processes occurring during sleep. Furthermore, increased negative affect may indicate which experiences are salient and require consolidation to form long-lasting memories that can guide future behaviour. Conclusion These findings have implications for psychiatric disorders, such as major depression, which is characterised by negative affect and increased memory sensitivity to negative stimuli.","PeriodicalId":73106,"journal":{"name":"Frontiers in sleep","volume":"53 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-10-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"136210724","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Optimizing intervention components for sleep promotion in children in the context of obesity prevention: the SLEEPY 2.0 study protocol","authors":"Maddy Fair, Jessica Decker, Alexander G. Fiks, Stephanie Mayne, Knashawn H. Morales, Ariel A. Williamson, Jonathan A. Mitchell","doi":"10.3389/frsle.2023.1264532","DOIUrl":"https://doi.org/10.3389/frsle.2023.1264532","url":null,"abstract":"Background Insufficient sleep duration is highly prevalent in childhood and is associated with obesity, especially among middle school-aged children. The primary care setting has enormous potential to promote sleep, but limited time and sleep resources at in person appointments are key barriers. Digital health innovations offer solutions to these barriers. Mobile health platforms can be developed to deliver behavioral sleep promotion remotely in the home setting, with tailoring to individual and contextual factors to help ensure equitable effectiveness across sociodemographic groups. This paper presents the protocol for a randomized optimization trial using the Multiphase Optimization Strategy (MOST) to develop a mobile health platform for the pediatric care setting to promote longer sleep duration for childhood obesity prevention. Methods This is a single-site study being conducted at the Children's Hospital of Philadelphia. We will randomize 325 children, aged 8–12 y, with a body mass index (BMI) between the 50th−95th percentile, and who sleep <8.5 h per night. The Way to Health mobile platform will facilitate remote communication and data collection. A sleep tracker will estimate sleep patterns for 12-months (2-week run-in; 6-month intervention; ≈5.5-month follow-up). A randomized 2 4 factorial design will assess four components: sleep goal (≥9 h or ≥30 min above baseline sleep duration), digital guidance (active or active with virtual study visits), caregiver incentive (inactive or active), and performance feedback (inactive or active). Fat mass will be measured at baseline, 6-, and 12-months using dual energy X-ray absorptiometry. Total energy intake and the timing and composition of meals will be measured using 24-h dietary recalls at baseline, 6-, and 12-months. Sociodemographic data (e.g., sex, race, ethnicity) will be measured using self-report and home addresses will be geocoded for geospatial analyses. Discussion We anticipate that this innovative optimization trial will identify optimal component settings for sleep promotion in children, with clinically meaningful improvements in fat mass trajectories. Importantly, the platform will have broad impact by promoting sleep health equity across sociodemographic groups. With the optimal settings identified, we will be able to determine the effectiveness of the final intervention package under the evaluation phase of the MOST framework in a future randomized controlled trial. Our proposed research will greatly advance the field of behavioral sleep medicine and reimagine how insufficient sleep duration and obesity are prevented in pediatric healthcare. Trial registration ClinicalTrials.gov NCT05703347 registered on 30 January 2023.","PeriodicalId":73106,"journal":{"name":"Frontiers in sleep","volume":"15 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-10-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135591631","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Enhanced expiratory rebreathing space for high loop gain sleep apnea treatment","authors":"Thomas Quinn, Robert Joseph Thomas, Eric James Heckman","doi":"10.3389/frsle.2023.1248371","DOIUrl":"https://doi.org/10.3389/frsle.2023.1248371","url":null,"abstract":"The pathophysiology of sleep apnea goes beyond anatomic predisposition to airway collapse and includes additional factors such as arousal threshold and loop gain. High loop gain is a prominent feature in central and complex sleep apnea (with a mixture of obstructive and central features) where relative hypocapnia can lead to respiratory instability and periodic breathing. Existing therapies, including continuous positive airway pressure (CPAP) and adaptive servo-ventilators, often inadequately treat sleep apnea with high loop gain features. Enhanced expiratory rebreathing space (EERS) targets prevention of the hypocapnia that triggers central events in sleep by increasing dead space in amounts less than typical tidal volumes. This is accomplished by covering traditional exhalation ports on positive airway pressure masks and adding small additional tubing with distal exhalation and safety valves. This technique reduces carbon dioxide (CO 2 ) blow-off during arousals and the associated large recovery breaths, typically producing a maximal increase in resting CO 2 by 1–2 mmHg, thus increasing the CO 2 reserve and making it less likely to encounter the hypocapnic apneic threshold. Typically, the amount of EERS is titrated in response to central events and periodic breathing rather than aiming for a goal CO 2 level. Ideally CO 2 monitoring is used during titration of EERS and the technique is avoided in the setting of baseline hypercapnia. This method has been used in clinical practice at our sleep center for over 15 years, and retrospective data suggests an excellent safety profile and high rates of successful therapy including in patients who have previously failed CPAP therapy. Limitations include decreased effectiveness in the setting of leak and decreased tolerance of the bulkier circuit. EERS represents a simple, affordable modification of existing positive airway pressure modalities for treatment of central and complex sleep apnea. Areas of future study include randomized controlled trials of the technique and study of use of EERS in combination with adaptive ventilation, and pharmacologic adjuncts targeting high loop gain physiology.","PeriodicalId":73106,"journal":{"name":"Frontiers in sleep","volume":"5 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-09-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135193451","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A nap consolidates generalized perceptual learning","authors":"Katherine S. Reis, Shannon Heald, Sophia Uddin, Kimberly M. Fenn, Howard C. Nusbaum","doi":"10.3389/frsle.2023.1168511","DOIUrl":"https://doi.org/10.3389/frsle.2023.1168511","url":null,"abstract":"Previous research has demonstrated that a night's sleep can consolidate rote and generalized perceptual learning. Over a waking retention period following training, performance gains from learning significantly decline, but sleep can restore performance to levels found immediately after learning. Furthermore, when sleep precedes a waking retention period following training, performance is protected against loss. Other research demonstrating that rote learning can be consolidated by a night's sleep has shown that a relatively brief nap can consolidate rote learning. This suggests that short periods of sleep can produce consolidation, indicating that consolidation may not require successive sleep cycles over an entire night to emerge. However, previous research has demonstrated that there can be differences in sleep-dependent consolidation for rote and generalized learning. In this study, we investigated whether an opportunity for a 90-min midday nap was sufficient to consolidate generalized perceptual learning of synthetic speech. We recruited 75 participants from the University of Chicago community (mean age of 20.83) who completed a pretest, training, and posttest in the morning on perception of synthetic speech. Training and testing in this manner are known to result in substantial generalized learning of synthetic speech. Participants then returned in the afternoon and were either given an opportunity for a 90-min nap or remained awake for 90-min. Participants were then given another posttest later that evening, never hearing the same words twice during the experiment. Results demonstrated that participants who did not nap showed significant loss of learning at the evening posttest. In contrast, individuals who napped retained what they learned, and did not show loss of learning at the evening posttest. These results are consistent with the view that an opportunity for a 90-min midday nap can consolidate generalized learning, as only individuals with consolidated learning should be able to retain what they learned despite an intervening waking retention period. This is the first demonstration that generalized skill learning is subject to sleep-dependent consolidation in short durations of sleep and does not require a full night of sleep. This work has implications for understanding the basic neural mechanisms that operate to stabilize short-term learning experiences.","PeriodicalId":73106,"journal":{"name":"Frontiers in sleep","volume":"7 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-09-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135864632","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Feasibility of neck electrical impedance tomography to monitor upper airway dynamics during sleep","authors":"Vivien S. Piccin, Erick D. L. B. de Camargo, Rafaela G. S. Andrade, Vinícius Torsani, Fabíola Schorr, Priscilla S. Sardinha, Fernanda Madeiro, Pedro R. Genta, Marcelo G. Gregório, Carlos R. R. de Carvalho, Marcelo B. P. Amato, Geraldo Lorenzi-Filho","doi":"10.3389/frsle.2023.1238508","DOIUrl":"https://doi.org/10.3389/frsle.2023.1238508","url":null,"abstract":"Background There is a lack of non-invasive methods for monitoring the upper airway patency during sleep. Electrical impedance tomography (EIT) is a non-invasive, radiation-free tool that has been validated to monitor lung ventilation. We hypothesized that electrical impedance tomography (EIT) can be used for monitoring upper airway patency during sleep. Methods Sleep was induced in 21 subjects (14 males, age 43 ± 13 years, body mass index 32.0 ± 5.3 kg/m 2 ) with suspected obstructive sleep apnea (apnea-hypopnea index: 44 ± 37 events/h, range: 1–122 events/h) using low doses of midazolam. Patients wore a nasal mask attached to a modified CPAP device, allowing variable and controlled degrees of upper airway obstruction. Confirmation of upper airway patency was obtained with direct visualization of the upper airway using nasofibroscopy ( n = 6). The changes in total neck impedance and in impedance in four cranio-caudal regions of interest (ROIs) were analyzed. Results Total neck impedance varied in concert with breathing cycles and peaked during expiration in all patients. Group data showed a high cross-correlation between flow and impedance curves ( r = −0.817, p < 0.001). Inspiratory peak flow correlated with simultaneous neck impedance ( r = 0.866, p < 0.001). There was a high correlation between total neck impedance and velopharynx area ( r = 0.884, p < 0.001), and total neck impedance and oropharynx area ( r = 0.891, p < 0.001). Conclusions Neck EIT is sensitive and captures pharyngeal obstruction under various conditions. Neck EIT is a promising method for real-time monitoring of the pharynx during sleep.","PeriodicalId":73106,"journal":{"name":"Frontiers in sleep","volume":"15 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-09-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"136130984","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Sleep disorders and suicide attempts following discharge from residential treatment","authors":"Todd M. Bishop, Westley A. Youngren, John S. Klein, Katrina J. Speed, Wilfred R. Pigeon","doi":"10.3389/frsle.2023.1173650","DOIUrl":"https://doi.org/10.3389/frsle.2023.1173650","url":null,"abstract":"Introduction Suicide is a significant public health concern and its prevention remains a top clinical priority of the Veterans Health Administration. Periods of transition in care (e.g., moving from inpatient to outpatient care) represent a period of increased risk. Sleep disorders are prevalent amongst Veterans and are modifiable risk factor for suicide. The present study examined the relationship of sleep disorders to time to suicide attempt amongst Veterans known to have attempted suicide in the 180 days following discharge from a Mental Health Residential Rehabilitation Treatment Program. Method The present sample was comprised of all Veterans enrolled in services with the Veterans Health Administration known to have attempted suicide following discharge from a Mental Health Residential Rehabilitation Treatment Program during Fiscal Years 13 and 14 ( N = 1,489). To create this sample, electronic medical record data were extracted from two VHA data sources: the Corporate Data Warehouse and the Suicide Prevention Application Network. Results Cox regression models revealed that Veterans with a sleep disturbance ( N = 1,211) had a shorter time to suicide attempt than those without a sleep disturbance [Hazard Ratio (HR) = 1.16, CI (1.02–1.32)]. A subsequent Cox regression model including age, insomnia, nightmare disorder, and alcohol dependence revealed that sleep-related breathing disorders [HR = 1.19, CI (1.01–1.38)], alcohol dependence [HR = 1.16, CI (1.02–1.33)], and age group were associated with increased risk. Conclusion Findings indicate that sleep disturbance, primarily driven by sleep-related breathing disorders, was associated with time to suicide attempt in this sample of high-risk Veterans known to have attempted suicide in the 180 days following their discharge from a Mental Health Residential Rehabilitation Treatment Program. These findings reveal an opportunity to reduce risk through the screening and treatment of sleep disorders in high-risk populations.","PeriodicalId":73106,"journal":{"name":"Frontiers in sleep","volume":"70 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-09-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135015605","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Case report: A case of complete resolution of obstructive and central sleep apnea with Cheyne Stokes breathing in a patient with heart failure 60 days post-left ventricular assist device implantation","authors":"S. Mashaqi, Michael William, Stuart F. Quan, D. Combs, L. Estep, Salma I. Patel, Jyotsna Sahni, S. Parthasarathy","doi":"10.3389/frsle.2023.1228038","DOIUrl":"https://doi.org/10.3389/frsle.2023.1228038","url":null,"abstract":"Sleep-disordered breathing (obstructive and central sleep apnea) are common in patients with heart failure with reduced ejection fraction. Herein, we report a 69-year-old patient with a history of severe heart failure and refractory ventricular arrhythmia who was diagnosed with a moderate degree of obstructive and central sleep apnea with Cheyne Stokes breathing. He underwent a successful implantation of left ventricular assist device. Our patient had a complete resolution of both obstructive and central sleep apnea 60 days post-LVAD implantation as confirmed by home sleep apnea test.","PeriodicalId":73106,"journal":{"name":"Frontiers in sleep","volume":"24 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-09-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"87027351","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Chronic insomnia: are patients also suffering from PTSD symptoms?","authors":"Emma Lardant, François Vialatte, Céline Ramdani, Frédéric Chauveau, C. Gauriau, Léna Storms, Marion Trousselard, Damien Léger","doi":"10.3389/frsle.2023.1207232","DOIUrl":"https://doi.org/10.3389/frsle.2023.1207232","url":null,"abstract":"Insomnia is highly prevalent in the general population, and is commonly associated with somatic and psychiatric comorbidities. However, its origins remain poorly-understood. Recently, adverse childhood events (ACE), including traumatic experiences, have been found to be significantly associated with both insomnia and Post-Traumatic Stress Disorders (PTSD). Many patients with PTSD suffer from sleep disorders. However, we know much less about traumatic childhood experiences in patients with insomnia and PTSD.Our exploratory study investigated a cohort of 43 patients (14 males, 29 females) clinically diagnosed with chronic insomnia at a sleep center, and systematically evaluated their condition using the trauma history questionnaire (THQ), and the PTSD checklist (PCL-5).Our results show that 83.72% of insomnia patients reported at least one traumatic event, while the prevalence of PTSD symptoms was 53.49%. For 11.6% of patients, insomnia began in childhood, while for 27.07% it began in adolescence. PCL-5 scores were associated with higher Insomnia Severity Index (ISI) scores, but not trauma. ISI scores were also higher for women, and positive relationships were observed between ISI scores, PCL-5 scores and the number of self-reported traumatic events among women.These exploratory results highlight that the relationship between PTSD symptoms and insomnia could be sex-specific. They also highlight the importance of PTSD symptoms screening for patients diagnosed with chronic insomnia.","PeriodicalId":73106,"journal":{"name":"Frontiers in sleep","volume":"80 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-09-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"89402524","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Obstructive sleep apnea phenotypes eligible for pharmacological treatment","authors":"Marie Bruyneel","doi":"10.3389/frsle.2023.1261276","DOIUrl":"https://doi.org/10.3389/frsle.2023.1261276","url":null,"abstract":"Obstructive sleep apnea (OSA) is a common disorder. Its prevalence is increasing worldwide, partially due to increasing rates of obesity, and OSA has a well-documented impact on physical health (increased risk of cardiovascular and metabolic disorders) and mental health, as well as major socioeconomic implications. Although continuous positive airway pressure treatment (CPAP) remains the primary therapeutic intervention for moderate to severe OSA, other treatment strategies such as weight loss, positional therapy, mandibular advancement devices (MAD), surgical treatment, myofunctional therapy of upper airways (UA) muscles and hypoglossal nerve stimulation are increasingly used. Recently, several trials have demonstrated the clinical potential for various pharmacological treatments that aim to improve UA muscle dysfunction, loop gain, or excessive daytime sleepiness. In line with the highly heterogeneous clinical picture of OSA, recent identification of different clinical phenotypes has been documented. Comorbidities, incident cardiovascular risk, and response to CPAP may vary significantly among phenotypes. With this in mind, the purpose of this review is to summarize the data on OSA phenotypes that may respond to pharmacological approaches.","PeriodicalId":73106,"journal":{"name":"Frontiers in sleep","volume":"277 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"80071415","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Sleep, internalizing symptoms, and health-related quality of life in children with neurodevelopmental disorders: a cross-sectional analysis of cohort data from three research programs in Canada","authors":"P. Mcphee, S. Georgiades, Andrea Andrade, P. Corkum, A. Vaccarino, Heena Cheema, Rachel Chepesiuk, A. Iaboni, J. Gorter","doi":"10.3389/frsle.2023.1224610","DOIUrl":"https://doi.org/10.3389/frsle.2023.1224610","url":null,"abstract":"The objectives of this study were to determine rates of sleep disturbances in children with neurodevelopmental disorders (NDDs) within and across disorders and compared to typically developing (TD) children and to describe differences above and below the clinical cut-off for sleep disturbances. In addition, we explored the associations between demographic variables, severity of disorder, sleep disturbances, internalizing symptoms, and health-related quality of life (HRQOL) in children with NDDs.We conducted cross-sectional data analyses of an existing database with community-dwelling children with NDDs (n = 1438) and TD children (n = 140) aged 4–12 years. Parent-reported measures on sleep disturbances using the Children's Sleep Habits Questionnaire (CSHQ), internalizing symptoms using the Revised Children's Anxiety and Depression Scale, and HRQOL using the KINDL-R were assessed. Hierarchical linear regression examined the associations between demographic variables, severity of disorder, sleep disturbances, internalizing symptoms, and HRQOL in children with NDDs.Children with NDDs (8.5 ± 2.1 years, 69.9% M) had significantly greater total sleep disturbance index (TSDI) than TD children [(8.6 ± 2.3 years, 60.0% M) (mean difference = 6.88 [95% CI 5.37, 8.40]; p < 0.001) (n = 838 NDDs (58.3%); n = 120 TD (86.7%)]. Children with severe NDDs reported significantly greater TSDI above the clinical cut-off (i.e., ≥41; CSHQ) than those with less severe NDDs (p < 0.001). Internalizing symptoms (β = −0.082 [95% CI −0.144, −0.019]; p = 0.011) and TSDI (β = −0.226 [95% CI −0.380, −0.073]; p = 0.004) were significantly associated with HRQOL in children with NDDs.Surveillance and management of sleep and internalizing symptoms are needed to improve HRQOL in children with NDDs. Commonalities in sleep disturbances for children with NDDs support transdiagnostic interventions to treat sleep.","PeriodicalId":73106,"journal":{"name":"Frontiers in sleep","volume":"150 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-08-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"77393097","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}