Frontiers in reproductive health最新文献

{"title":"Successful live birth of a healthy infant by preimplantation genetic testing for aneuploidy in a couple with recurrent spontaneous abortion: a case report.","authors":"Yuqin Zhu, Zhuoyao Mai, Ruiqi Li, Zaowen Liao, Nengyong Ouyang, Hui Chen, Haijing Zhao","doi":"10.3389/frph.2025.1627160","DOIUrl":"10.3389/frph.2025.1627160","url":null,"abstract":"<p><p>Recurrent spontaneous abortion (RSA), characterized by the occurrence of three or more pregnancy losses prior to the 28th week of gestation, stands as a formidable challenge in the realm of assisted reproductive medicine, presenting significant difficulties in both clinical diagnosis and treatment. In recent years, there has been a discernible upward trend in the incidence of RSA, and its etiology is multifaceted and intricate. Pinpointing the root causes of RSA remains an arduous task that urgently demands resolution within the field of reproductive medicine. Through a comprehensive and in-depth analysis of the RSA-related case report, embryonic chromosomal abnormalities were identified as the highest-risk factor. Utilizing preimplantation genetic testing for aneuploidy (PGT-A) technology, an euploid blastocyst was selected for transfer, which led to successful pregnancy and healthy birth. This case holds significant reference value for the clinical treatment of RSA.</p>","PeriodicalId":73103,"journal":{"name":"Frontiers in reproductive health","volume":"7 ","pages":"1627160"},"PeriodicalIF":2.9,"publicationDate":"2025-08-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12370523/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144981074","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Use of modern contraceptives on the basis of disability severity in Uganda: analysis of the 2016 demographic and health survey.","authors":"Tara Casebolt, Molly Hardiman, Taylor Diaz-Leon Guerrero","doi":"10.3389/frph.2025.1611713","DOIUrl":"10.3389/frph.2025.1611713","url":null,"abstract":"<p><strong>Background: </strong>Women with disabilities have faced difficulties with accessing family planning services for decades and in many different settings. These women have both been denied access to contraception because of an inaccurate belief of the asexuality of people with disabilities and been forced or coerced into using contraceptives because of the belief they should not have children.</p><p><strong>Objective: </strong>This study uses Demographic and Health Survey data to analyze the association between disability and modern contraceptive use in Uganda. A disability severity indicator was used based upon recommendations from the Washington Group on Disability Statistics.</p><p><strong>Methods: </strong>Bivariate analysis was performed using chi-squares to determine if a significant association exists between modern contraceptive use and disability. Logistic regressions were run to generate odds ratios for crude adjusted models which took demographic data and covariates into consideration.</p><p><strong>Results: </strong>Disability was not found to be significantly associated with modern contraceptive use. Women with disabilities did not have significantly different odds of using a modern form of contraceptive when compared to women without disabilities in both the crude and adjusted models.</p><p><strong>Conclusions: </strong>These findings are inconsistent with previous studies conducted in Uganda. Additional research should be conducted to determine if there are disparities in the type of contraceptive used, sustainability of the method, and whether there is an unmet need for contraceptives. Based on the findings of this study, it is clear that women with disabilities use contraceptives. Therefore, it is essential for family planning services to be accessible to women regardless of functional limitations.</p>","PeriodicalId":73103,"journal":{"name":"Frontiers in reproductive health","volume":"7 ","pages":"1611713"},"PeriodicalIF":2.9,"publicationDate":"2025-08-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12367744/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144981137","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Breaking barriers, changing paradigms: Africa's radical agenda for HIV sustainability.","authors":"Mumbi Chola, Magda Robalo, Kent Buse, Pokuaa Oduro-Bonsrah, Jekwu Ozoemene, Abdoul Dieng, Ruth Akulu, Bernard Madzima, Awa Marie Coll-Seck, Robb Sheneberger, Sesupo Makakole Nene, Izukanji Sikazwe, Michel Sidibe","doi":"10.3389/frph.2025.1612902","DOIUrl":"10.3389/frph.2025.1612902","url":null,"abstract":"<p><p>Despite significant progress in the HIV response, the sustainability of this journey is threatened by over-reliance on external support and imported and often inappropriate models. The recent sudden shifts in the United States Government's foreign aid policy have heightened the urgency for independence. Africa is at a critical point, which presents an opportunity to move from dependency on external assistance to establishing itself as a self-sustaining center of innovation and sustainable growth. Africa must reshape its approach to the HIV response by addressing the continent's over-reliance on external funding and shift towards self-sustainability and inclusiveness. For Africa to sustain its HIV response, it is critical to have African voices and leadership in the HIV response, adopt African-centric approaches in moving from silos to the integration of programme governance, ensure renewed governance and accountability frameworks, Africanizing research and development and also ensure African medicines security and sovereignty. Africa must leverage Ubuntu approaches to empowering communities, women, youth, and key and vulnerable populations, and work with community networks for service delivery. There must also be sustained HIV Programmes in Fragile and Post-conflict Settings. It is also critical to secure domestic financing through a continental approach to financing health and well-being. For Africa to realize the vision of a sustainable, African-led, and owned HIV response and health agenda, collective action is imperative. African stakeholders must fully support this agenda and claim it as their own in the spirit of Ubuntu, within the context of continental plans for transformation and revitalization. Together, we can realize the vision of the \"Africa we want.\"</p>","PeriodicalId":73103,"journal":{"name":"Frontiers in reproductive health","volume":"7 ","pages":"1612902"},"PeriodicalIF":2.9,"publicationDate":"2025-08-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12367654/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144980955","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Spatial variation of correct knowledge of the ovulatory cycle and its associated factors among reproductive age women in Ethiopia: geographically weighted regression analysis.","authors":"Werkneh Melkie Tilahun, Lamrot Yohannes Abay, Fantu Mamo Aragaw, Zenebe Abebe Gebreegziabher, Tigabu Kidie Tesfie","doi":"10.3389/frph.2025.1505749","DOIUrl":"10.3389/frph.2025.1505749","url":null,"abstract":"<p><strong>Background: </strong>Information about reproductive physiology like the ovulatory cycle helps women to understand their pregnancy risk and appropriately plan their pregnancies, which can reduce unintended pregnancy and the true risk of conception. Thus, this study aimed to explore the spatial variation of correct knowledge of the ovulatory cycle (KOC) across regions of Ethiopia and identify associated factors.</p><p><strong>Methods: </strong>A cross-sectional study design was employed based on the 2016 Ethiopian demographic and health survey. A total of 15,683 weighted samples were included. Geographically weighted regression and ordinary least square analysis were conducted. Models were compared using AICc & adjusted <i>R</i> ². A <i>P</i>-value of less than 0.05 was used to declare statistically significant spatial predictors.</p><p><strong>Results: </strong>In our study, only 23.58% [95% CI; 22.92-24.25%] of reproductive-age women had correct KOC. Significant hot spots were identified in Addis Ababa, Dire Dawa, and Hareri. Different factors showed a spatially significant effect on correct KOC. Media exposure showed positive effects ranging from 0.34 to 0.57 in the Somali, Amhara, Oromia, Addis Ababa, and SNNPR regions. Rich wealth status showed a positive spatial effect ranging from 0.13 to 0.54 in Benishangul Gumuz, most of Gambela, western Oromia, western Amhara, and Northwestern SNNPR. Proximity to health facilities had a positive effect ranging from 0.15 to 0.227 in Dire Dawa, Harari, eastern Oromia, and eastern and southeastern Somali. In most of the Amhara, Afar, Gambela, western and central Oromia, Benishangul, and Somali regions, education had a significant positive effect range of 0.23-0.36. In Dire Dawa, Harari, Somali, the majority of Oromia, and SNNPR regions, high community-level FP messages had a positive effect with a range of 0.28-0.39.</p><p><strong>Conclusion: </strong>In this study, the correct KOC among reproductive-aged women was found to be low. Significant spatial variation of the correct KOC among reproductive-age women was observed. Given the importance of formal education, rich household wealth status, media exposure, high community-level FP media exposure, and proximity to a health institution, area-based interventions that can take into account these important factors are needed to promote appropriate KOC.</p>","PeriodicalId":73103,"journal":{"name":"Frontiers in reproductive health","volume":"7 ","pages":"1505749"},"PeriodicalIF":2.9,"publicationDate":"2025-08-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12364825/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144981130","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Clinical observation of transurethral reconstruction of urethral meatus and navicularis fossa short strictures with annular inlay oral mucosa graft urethroplasty.","authors":"Zhenyu Li, Zhiguang Zhao, Geng Zhang, He Wang, Bo Zhang, Wei Zhang","doi":"10.3389/frph.2025.1555597","DOIUrl":"10.3389/frph.2025.1555597","url":null,"abstract":"<p><strong>Objective: </strong>This study aims to explore the clinical efficacy and safety of a urethroplasty technique for fossa navicularis (FN) strictures using a transurethral annular inlay oral mucosa graft.</p><p><strong>Methods: </strong>A retrospective analysis was conducted on clinical data from patients with urethral meatus and navicular fossa stricture who underwent transurethral reconstruction using annular inlay oral mucosa graft urethroplasty in Tangdu Hospital from July 2021 to October 2024. Operation success was defined as the ability to pass the F24 urethral probe, and the secondary outcome is the urinary flow rate and patient satisfaction at 1, 3, 6, and 12 months.</p><p><strong>Results: </strong>All 12 patients successfully completed the surgery. The average age was 56.8 ± 6.8 years, and the average length of urethral stricture was 1.6 ± 0.2 cm. Three patients had a history of transurethral endoscopic surgery, eight had penile lichen sclerosus (LS), and one had no obvious causes. Over a median follow-up of 19 months, the average maximum urinary flow rate was 21.2 ± 3.2 ml/s at 3 months, and the average maximum urinary flow rate was 19.5 ± 4.2 ml/s at 12 months. One patient experienced urine pain with a thin stream and spraying urination after 3 months. Physical examination of the urethral meatus opening scar was found, and the symptoms disappeared after urethral incision. The follow-up survey of sexual life after 1 year showed that seven patients (58.3%) had successful life within 1 year compared with two patients (16.7%) before surgery. There were no cases of erectile dysfunction and poor wound healing. The patients were either very satisfied (75%) or satisfied (25%) with the operation. All patients would recommend urethroplasty to others.</p><p><strong>Conclusion: </strong>Transurethral annular inlay oral mucosa urethroplasty for urethral meatus and navicular fossa stricture reconstruction is a safe, feasible, and effective surgical method, cosmetic effect on the penile head. This technique has advantages in improving sexual function and better penile head cosmesis.</p>","PeriodicalId":73103,"journal":{"name":"Frontiers in reproductive health","volume":"7 ","pages":"1555597"},"PeriodicalIF":2.9,"publicationDate":"2025-08-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12361236/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144980952","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Editorial: Highlights in assisted reproduction 2023/24.","authors":"Eitan Lunenfeld, Johnny S Younis","doi":"10.3389/frph.2025.1648172","DOIUrl":"10.3389/frph.2025.1648172","url":null,"abstract":"","PeriodicalId":73103,"journal":{"name":"Frontiers in reproductive health","volume":"7 ","pages":"1648172"},"PeriodicalIF":2.9,"publicationDate":"2025-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12354581/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144877111","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Advertising support in healthcare settings for survivors of sexual violence: findings from a population-based survey in England.","authors":"Aliyu Abubakar, Jonathan D C Ross, Rachel J Caswell","doi":"10.3389/frph.2025.1642585","DOIUrl":"10.3389/frph.2025.1642585","url":null,"abstract":"<p><strong>Introduction: </strong>Sexual violence (SV) is common, but accessing appropriate support is frequently a challenge. Understanding how best to advertise healthcare support after SV could potentially improve access and long-term outcomes. This study investigates factors associated with increasing the visibility of advertisements for SV support in healthcare settings, and variations in the relevance of advertisements to different population sub-groups.</p><p><strong>Methods: </strong>An online, population-based survey was conducted in England. The survey collected demographic data, history of whether they had seen SV support information and its perceived relevance.</p><p><strong>Results: </strong>Overall, 2,007 respondents aged 18 years and above completed the survey. On multivariate analysis, younger age groups were significantly more likely to report seeing SV support advertisements compared to those aged 55 or older-individuals aged 18-24 years (AOR = 2.23, 95% CI = 1.36-3.65) and 25-34 years (AOR = 2.26, 95% CI = 1.43-3.57). Ethnicity and prior experience of SV were also significant predictors, with White respondents more likely to have seen the advertisements (AOR = 5.52, 95% CI = 1.81-16.85), as were those with a history of SV (AOR = 1.66, 95% CI = 1.34-2.05). Respondents aged 18-24 years (AOR = 3.29, 95% CI = 1.80-6.04) and 25-34 years (AOR = 2.32, 95% CI = 1.34-4.04) reported SV support information to be more relevant to them than those aged 55 or older, as did individuals with a history of SV (AOR = 1.82, 95% CI = 1.42-2.33).</p><p><strong>Conclusions: </strong>The findings suggest younger people and those of White ethnicity and with a history of SV are more likely to see SV support information and perceive it as relevant. Advertising strategies targeting high-risk populations are essential to ensure equitable access to care.</p>","PeriodicalId":73103,"journal":{"name":"Frontiers in reproductive health","volume":"7 ","pages":"1642585"},"PeriodicalIF":2.9,"publicationDate":"2025-07-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12350387/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144877110","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Exploring the temporal shift in menstrual hygiene practices among young women across India: a micro and macro perspectives.","authors":"S K Singh, Bharti Singh","doi":"10.3389/frph.2025.1532178","DOIUrl":"10.3389/frph.2025.1532178","url":null,"abstract":"<p><strong>Background: </strong>Lack of menstrual hygiene practices (MHP) is one of the primary causes of reproductive morbidities among young women. The recent National Family Health Survey (NFHS) showed a significant increase in the use of hygienic menstrual methods in India. This paper aims to investigate the spatial and temporal changes in the prevalence of hygienic menstrual practices from 2016 to 2021, considering micro and macro perspectives.</p><p><strong>Method: </strong>The study is based on women aged 15-24. The Datasets used in this study are from two recent rounds of the National Family Health Survey, NFHS-4 and NFHS-5. Descriptive, bivariate, multilevel, spatial, and Fairlie decomposition methods have been used to analyze spatial and temporal changes in MHP.</p><p><strong>Results: </strong>The study illustrates that the prevalence of MHP has increased by 20% points over the past five years, with a significant rise in the use of sanitary napkins, even among marginalized groups. Spatial variation and temporal changes reveal the influence of geospatial attributes, awareness, education, sanitation, and economic prosperity on MHP. Multilevel analysis portrays the maximum clustering in the MHP at the household level in both survey years. Further, Fairlie decomposition reveals that media exposure, followed by the educational attainment of women, contributes highest to the increase in MHP from NFHS-4 to NFHS-5.</p><p><strong>Conclusion: </strong>The findings of the study present a significant amount of influence of geospatial attributes, including culture and tradition. The extent of \"awareness\" regarding menstrual hygiene emerged as the most critical driver of escalating MHP in the country. Therefore, addressing socio-economic disparities and implementing interventions through community-level programs, preferably by adopting peer-based approaches with the active participation of self-help groups and frontline workers, is necessary to ensure universal access to sanitary methods.</p>","PeriodicalId":73103,"journal":{"name":"Frontiers in reproductive health","volume":"7 ","pages":"1532178"},"PeriodicalIF":2.9,"publicationDate":"2025-07-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12343603/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144849923","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Editorial: Oxidative stress and male fertility.","authors":"Roland E Akhigbe","doi":"10.3389/frph.2025.1657872","DOIUrl":"10.3389/frph.2025.1657872","url":null,"abstract":"","PeriodicalId":73103,"journal":{"name":"Frontiers in reproductive health","volume":"7 ","pages":"1657872"},"PeriodicalIF":2.9,"publicationDate":"2025-07-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12336187/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144823345","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Lived experiences of adults living With HIV/AIDS receiving antiretroviral therapy at werabe comprehensive specialized hospital in Silte zone, Ethiopia.","authors":"Abdulmejid Mustefa, Lonsako Abute, Kemal Lemnuro, Abdulkerim Badgeba, Delwana Bedru, Bisrat Feleke Bubamo, Gizachew Beykaso, Feleke Doyore Agide, Abinet Arega Sadore","doi":"10.3389/frph.2025.1494390","DOIUrl":"10.3389/frph.2025.1494390","url":null,"abstract":"<p><strong>Background: </strong>The HIV/AIDS pandemic has had a profound impact on patients' lives on all fronts, as well as on society. Examining adult PLWHA experiences from various angles helps find gaps, develop plans, and put policies and coping mechanisms in place. Therefore, this study aimed to explore the lived experiences of adult patients receiving ART at Werabe Comprehensive Specialized Hospital in Ethiopia.</p><p><strong>Method: </strong>A qualitative approach with a phenomenological study design was used from March to June 2022 among 12 purposively selected adults on ART at the Worabe Comprehensive Specialized Hospital. Data were collected using semi-structured, open-ended questions. In-depth interviews were audiotaped, transcribed verbatim, and analyzed using qualitative data management software (ATLAS Ti version 7.1.4). The findings were summarized under five themes by applying inductive thematic analysis.</p><p><strong>Results: </strong>This study explored five themes that included (I) experiences at the time of diagnosis of their positive HIV Status with two sub-themes: inappropriate counseling and difficulty in accepting positive results; (II) disease management skills with three sub-themes: ART Initiation, Perceived health importance of ART; (III) Enacted stigma with two sub-themes: Stigma & Discrimination and Disclosure; (IV) Experiences towards gaining support with three sub-themes: Family care, Peer/social support from organizations and Hospital and Health professionals' care; and (V) perceptions towards health status and feelings about their status with three sub-themes of living as normal life, feeling about their HIV status and vision of purposeful life.</p><p><strong>Conclusions: </strong>Creating educational initiatives and consistently educating the public about health issues can greatly increase public knowledge of HIV, alter perceptions of the virus, and influence how others behave when interacting with people with HIV/AIDS. This mental shift fosters social support and lessens the obstacles to the acceptance of infection by PLWHA.</p>","PeriodicalId":73103,"journal":{"name":"Frontiers in reproductive health","volume":"7 ","pages":"1494390"},"PeriodicalIF":2.9,"publicationDate":"2025-07-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12336256/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144823346","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}