Frontiers in reproductive health最新文献

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Scoping review of social norms interventions to reduce violence and improve SRHR outcomes among adolescents and young people in sub-Saharan Africa. 对撒哈拉以南非洲青少年和年轻人减少暴力和改善SRHR结果的社会规范干预措施进行范围审查。
IF 2.3
Frontiers in reproductive health Pub Date : 2025-05-15 eCollection Date: 2025-01-01 DOI: 10.3389/frph.2025.1592696
Luciana Leite, Rachel Yates, Gaia Chiti Strigelli, Jenny Yi-Chen Han, Jenny Chen-Charles, Maria Rotaru, Elona Toska
{"title":"Scoping review of social norms interventions to reduce violence and improve SRHR outcomes among adolescents and young people in sub-Saharan Africa.","authors":"Luciana Leite, Rachel Yates, Gaia Chiti Strigelli, Jenny Yi-Chen Han, Jenny Chen-Charles, Maria Rotaru, Elona Toska","doi":"10.3389/frph.2025.1592696","DOIUrl":"https://doi.org/10.3389/frph.2025.1592696","url":null,"abstract":"<p><strong>Introduction: </strong>Despite growing interest, guidance to inform effective social norms interventions that improve adolescents and young people's sexual and reproductive health and rights (SRHR) is needed.</p><p><strong>Methods: </strong>We conducted a scoping review of experimental and quasi-experimental studies of social norms interventions in sub-Saharan Africa. Single and multi-component interventions that included a social norms component and assessed impacts on SRHR outcomes among 10- to 24-year-old adolescents and young people were included. We mapped interventions across eight programmatic strategies and six SRHR outcomes, drawing programmatic insights.</p><p><strong>Results: </strong><i>N</i> = 40 interventions from 12 countries reported effectiveness on intimate partner and non-partner sexual, physical and emotional violence (<i>N</i> = 14), child marriage (<i>N</i> = 6), sexual risk behaviours (<i>N</i> = 20), contraception and family planning (<i>N</i> = 23), prevention and treatment of HIV and other sexually transmitted infections (<i>N</i> = 17), and early pregnancy (<i>N</i> = 10). Intervention strategies included life skills approaches (<i>N</i> = 23), community dialogues (<i>N</i> = 14), school-based SRHR programming (<i>N</i> = 10), parenting programmes (<i>N</i> = 8), training of healthcare professionals on youth-friendly services (<i>N</i> = 7), media or digital-based approaches (<i>N</i> = 7), interventions with community leaders (<i>N</i> = 5), and rights-based advocacy (<i>N</i> = 2). Norms interventions can improve multiple SRHR outcomes, including reducing gender-based and intimate partner violence and child marriage, increasing HIV testing, and contraceptive use. Effective programmes were often implemented in combined interventions, and included life skills, community conversations, mass media and digital programmes with norms components.</p><p><strong>Discussion: </strong>Integrating gender-transformative approaches such as reflections on gender roles and inequalities, youth sexuality, and gendered power relations, and engaging with reference groups were key to the success of programmes. Effective approaches delivered SRHR information alongside reflections on social norms, and combined participatory methods with a structured curriculum guiding activities led by trained facilitators. Most interventions focused on changing social expectations and awareness, but few reported clear diffusion strategies to ensure the spread of the new norms and behaviours for the expected change. Key evidence gaps identified include integrating implementation research to inform the scale-up and sustainability of effective social norms interventions. Social norms interventions that effectively address the needs of high-risk adolescents and young people are needed.</p>","PeriodicalId":73103,"journal":{"name":"Frontiers in reproductive health","volume":"7 ","pages":"1592696"},"PeriodicalIF":2.3,"publicationDate":"2025-05-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12119623/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144182497","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
"One's life becomes even more miserable when we hear all those hurtful words". A mixed methods systematic review of disrespect and abuse in abortion care. “当我们听到那些伤人的话时,一个人的生活变得更加悲惨。”人工流产护理中不尊重和虐待的混合方法系统综述。
IF 2.3
Frontiers in reproductive health Pub Date : 2025-05-15 eCollection Date: 2025-01-01 DOI: 10.3389/frph.2025.1561707
Meghana Munnangi, Priya Shreedhar, Regina Gilyan, Hedda Lippus, Dabney P Evans, Lauren Maxwell
{"title":"\"One's life becomes even more miserable when we hear all those hurtful words\". A mixed methods systematic review of disrespect and abuse in abortion care.","authors":"Meghana Munnangi, Priya Shreedhar, Regina Gilyan, Hedda Lippus, Dabney P Evans, Lauren Maxwell","doi":"10.3389/frph.2025.1561707","DOIUrl":"https://doi.org/10.3389/frph.2025.1561707","url":null,"abstract":"<p><strong>Background: </strong>Disrespect and abuse during facility-based abortion and postabortion care (PAC) manifests in various forms, including disrespect, abuse (physical, verbal, and sexual), stigma, discrimination, failure to meet standards of care, neglect, breaches in privacy and confidentiality, misinformation or a lack of information, mistreatment or undignified care, and the presence of protestors. The objective of this mixed methods systematic review was to describe the various forms of disrespect and abuse that women face based on their personal experiences during facility-based abortion care or PAC.</p><p><strong>Methods: </strong>We conducted a comprehensive literature search in Embase, Medline, and PubMed using Medical Subject Headings (MeSH) and text-based terms targeting disrespect and abuse in facility-based abortion care. The initial search was conducted in 2019, followed by an updated search in 2023. Thirty-eight studies conducted in 20 countries met the inclusion criteria and were included in this review.</p><p><strong>Results: </strong>The most frequently observed form of disrespect and abuse, identified in 33 studies, was the failure to meet care standards in providing quality abortion care or PAC, particularly in terms of offering adequate and accurate information to women before, during and after the procedures which was identified in 21 studies. Additionally, stigma was reported in 22 studies, disrespect in 19 studies, discrimination in 10 studies, and verbal, physical and sexual abuse, as well as humiliation and condescension, each in 9 studies. The presence and impact of abortion protestors were also looked at in 8 studies.</p><p><strong>Conclusions: </strong>Our results indicate the need for multi-level strategies to transform healthcare providers' perceptions and attitudes towards women seeking abortion care and other actions at the individual, institutional, and policy levels to provide quality, respectful abortion care and PAC. This systematic measurement of disrespect and abuse in facility-based abortion care and PAC can help understand the distribution of experiences across different groups.</p>","PeriodicalId":73103,"journal":{"name":"Frontiers in reproductive health","volume":"7 ","pages":"1561707"},"PeriodicalIF":2.3,"publicationDate":"2025-05-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12119581/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144183137","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Barriers to sexual and reproductive health communication in Southwest Ethiopia: perspectives of parents, youths, and teachers. 埃塞俄比亚西南部性健康和生殖健康交流的障碍:父母、青年和教师的观点。
IF 2.3
Frontiers in reproductive health Pub Date : 2025-05-13 eCollection Date: 2025-01-01 DOI: 10.3389/frph.2025.1444603
Abraham Tamirat Gizaw, Sualiha Abdulkader Muktar, Yohannes Addisu Wondimagegene, Mengistu Abayneh, Belay Zeleke Sefere, Kasahun Girma Tareke, Abebayehu N Yilma
{"title":"Barriers to sexual and reproductive health communication in Southwest Ethiopia: perspectives of parents, youths, and teachers.","authors":"Abraham Tamirat Gizaw, Sualiha Abdulkader Muktar, Yohannes Addisu Wondimagegene, Mengistu Abayneh, Belay Zeleke Sefere, Kasahun Girma Tareke, Abebayehu N Yilma","doi":"10.3389/frph.2025.1444603","DOIUrl":"https://doi.org/10.3389/frph.2025.1444603","url":null,"abstract":"<p><strong>Background: </strong>Youths throughout the world face considerable challenges related to their sexual and reproductive health (SRH). In Ethiopia, the adolescent and youth groups account for nearly half the population. Parents play a vital role in SRH communication. Parents' communication with their children regarding SRH is considered an important part of adolescent development, as this contributes to optimizing safe SRH. Therefore, this study aimed to explore barriers to SRH communication from the perspectives of parents, youths, and teachers in Southwest Ethiopia.</p><p><strong>Methods: </strong>A qualitative research approach was used in four schools (two private and two public) in Jimma town. Data collection entailed 16 focused group discussions with parents and youths (15-24 years) and 12 key informant interviews with school directors, unit leaders, and school media coordinators. The interviews were audio-recorded, transcribed, and translated into English. Thematic analysis was conducted using ATLAS_ti software.</p><p><strong>Results: </strong>Participants recognized the crucial role parents play in SRH issues; however, only a few parents were involved in SRH communications, and there were many barriers raised by the participants. Barriers to SRH communications were parental lack of knowledge, cultural and religious beliefs, the effect of social media use, shame and stigma, and parental attitudes towards SRH communication.</p><p><strong>Conclusions: </strong>In summary, addressing barriers to sexual and reproductive health communication between parents and youth is crucial for fostering better health outcomes. Parents should be encouraged to have open discussions with their children from an early age. High schools should implement regular SRH education sessions with healthcare providers, while youth-friendly service clubs should focus on changing attitudes towards SRH communications through social and behavioral changes in communication.</p>","PeriodicalId":73103,"journal":{"name":"Frontiers in reproductive health","volume":"7 ","pages":"1444603"},"PeriodicalIF":2.3,"publicationDate":"2025-05-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12106455/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144163792","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Multipurpose prevention technologies for the prevention of unintended pregnancy, HIV, and other sexually transmitted infections: regulatory pathways and challenges. 预防意外怀孕、艾滋病毒和其他性传播感染的多用途预防技术:监管途径和挑战。
IF 2.3
Frontiers in reproductive health Pub Date : 2025-05-13 eCollection Date: 2025-01-01 DOI: 10.3389/frph.2025.1591232
Logan Donaldson, Robin Schaefer, Sarah Alhakimi, Ruth Akulu, Thesla Palanee-Phillips, Bethany Young Holt, Veronica Miller
{"title":"Multipurpose prevention technologies for the prevention of unintended pregnancy, HIV, and other sexually transmitted infections: regulatory pathways and challenges.","authors":"Logan Donaldson, Robin Schaefer, Sarah Alhakimi, Ruth Akulu, Thesla Palanee-Phillips, Bethany Young Holt, Veronica Miller","doi":"10.3389/frph.2025.1591232","DOIUrl":"https://doi.org/10.3389/frph.2025.1591232","url":null,"abstract":"&lt;p&gt;&lt;p&gt;Multipurpose prevention technologies (MPTs) are multi-indication products commonly focusing on the prevention of unintended pregnancy, HIV, and/or other sexually transmitted infections (STIs). MPTs have the potential to simplify product use and service delivery with reduced clinic visits, thus supporting improved product uptake, effective use, and cost-effectiveness. MPTs are complex products that typically include multiple active pharmaceutical ingredients (APIs), with two or more indications, and often use a device to deliver these APIs. These complexities create challenges when seeking regulatory approval. Products with previously approved APIs may be able to rely on bioequivalence (BE) studies, but still face challenges in formulation variation, drug-drug interaction, and fulfilling strict standards. MPTs that use new APIs and devices cannot rely on BE studies for approval and thus face further uncertainty, including clinical trial design for products with multiple indications and outcomes of interest. Efficacious standards of care for HIV prevention and contraception also necessitate active-control designs for registrational clinical trials, thus innovative trial designs may be needed. Compounding these challenges are special regulatory requirements for combination products, in addition to standards applied to individual API and device. Possible approval pathways for combination products exist within the US Food and Drug Administration and other global regulatory authorities, but their complexities and challenges are untested for MPTs. They are highlighted in this article to raise awareness around regulatory pathways for MPTs. In Sub-Saharan Africa, women of reproductive age are the largest percentage of new HIV infections. This, in combination with considerable rates of unintended pregnancy and rising sexually transmitted infection (STI) rates, highlights the need for products that address these complex sexual and reproductive health needs. Multipurpose prevention technologies (MPTs) commonly focus on the prevention of unintended pregnancy, HIV, and/or other STIs in one product. MPTs combine the use of multiple pharmaceutical drugs and often a medical device to address these interrelated challenges. This creates complications in the design of studies for MPTs and in understanding the process of approval from regulatory authorities. Regulatory authorities are responsible for ensuring the safety and effectiveness of health products, and in MPTs this is complicated by targeting the prevention of multiple indications, with differing study designs and challenges, in one product. There are mechanisms in place at some regulatory authorities to evaluate MPTs, but these pathways are untested by product developers and regulatory authorities alike. Some of these pathways are highlighted below. Collaboration between diverse stakeholders like regulators, academics, product developers, and community members is necessary to build consensus on the be","PeriodicalId":73103,"journal":{"name":"Frontiers in reproductive health","volume":"7 ","pages":"1591232"},"PeriodicalIF":2.3,"publicationDate":"2025-05-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12106464/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144163846","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The development of cervical intraepithelial neoplasia in three members of the same family: a case report. 宫颈上皮内瘤变的发展在同一家族的三个成员:一个病例报告。
IF 2.3
Frontiers in reproductive health Pub Date : 2025-05-13 eCollection Date: 2025-01-01 DOI: 10.3389/frph.2025.1542480
M A Vinokurov, A V Minaeva, G V Leshkina, T N Romanyuk, K O Mironov, V G Akimkin
{"title":"The development of cervical intraepithelial neoplasia in three members of the same family: a case report.","authors":"M A Vinokurov, A V Minaeva, G V Leshkina, T N Romanyuk, K O Mironov, V G Akimkin","doi":"10.3389/frph.2025.1542480","DOIUrl":"https://doi.org/10.3389/frph.2025.1542480","url":null,"abstract":"<p><strong>Background: </strong>Cervical cancer is the fourth most common cancer and cause of cancer-related death among women globally. Familial cases of cervical cancer highlight the potential role of genetic factors in its development. This study aims to present a clinical case of cervical intraepithelial neoplasia (CIN) affecting a woman and her two daughters.</p><p><strong>Case description: </strong>This report describes a familial case involving three patients diagnosed with cervical lesions: (1) Patient A: A 27-year-old woman presented with complaints of postcoital bleeding. She was diagnosed with high-grade squamous intraepithelial lesion (HSIL, CIN3). Radiowave conization of the cervix was performed, and histological examination confirmed the diagnosis of CIN3. (2) Patient B: A 25-year-old woman, the sister of Patient A, also presented with contact bleeding. She was similarly diagnosed with HSIL (CIN3). A radiowave conization procedure was performed successfully, with histopathological analysis confirming the diagnosis. (3) Patient C: A 52-year-old woman, the mother of Patients A and B, was diagnosed with low-grade squamous intraepithelial lesion (LSIL, CIN1) following cytological examination. She declined further diagnostic and therapeutic interventions. Genetic testing for all three patients revealed the presence of risk alleles associated with cervical cancer predisposition (rs10175462, rs1048943, rs4646903) and the absence of protective genotypes.</p><p><strong>Discussion: </strong>Familial cases of CIN are rare and suggest a potential genetic predisposition to the disease. The identification of common genetic polymorphisms underscores the role of hereditary factors in cervical cancer pathogenesis. These findings emphasize the importance of incorporating family history and genetic assessments into screening, diagnosis, and treatment strategies.</p><p><strong>Conclusion: </strong>This case highlights the significant influence of genetic factors in the development of cervical intraepithelial neoplasia. It underscores the need for further research to enhance strategies for early detection, prevention, and management of cervical cancer in individuals with elevated genetic risk.</p>","PeriodicalId":73103,"journal":{"name":"Frontiers in reproductive health","volume":"7 ","pages":"1542480"},"PeriodicalIF":2.3,"publicationDate":"2025-05-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12106530/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144163895","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Impact of menopause hormone therapy, exercise, and their combination on bone mineral density and mental wellbeing in menopausal women: a scoping review. 绝经期激素治疗、运动及其联合对绝经期妇女骨密度和心理健康的影响:范围综述
IF 2.3
Frontiers in reproductive health Pub Date : 2025-05-12 eCollection Date: 2025-01-01 DOI: 10.3389/frph.2025.1542746
Olivia Platt, James Bateman, Shagaf Bakour
{"title":"Impact of menopause hormone therapy, exercise, and their combination on bone mineral density and mental wellbeing in menopausal women: a scoping review.","authors":"Olivia Platt, James Bateman, Shagaf Bakour","doi":"10.3389/frph.2025.1542746","DOIUrl":"https://doi.org/10.3389/frph.2025.1542746","url":null,"abstract":"<p><strong>Background: </strong>Osteoporosis, a condition marked by low bone mineral density (BMD) and structural deterioration, affects more women than men over 50 globally. In women, declining estrogen during the menopause accelerates bone resorption, heightening fracture risk. An association between osteoporosis and depression, frailty fractures and poor quality of life has been identified. Both menopause hormone therapy (MHT) and exercise are shown to improve BMD, with MHT reducing bone resorption and exercise promoting bone formation. This review examines the effectiveness of MHT, exercise, and their combination in managing menopausal osteoporosis.</p><p><strong>Method: </strong>A multifactor scoping review was conducted to address osteoporosis and MHT, osteoporosis and exercise, and osteoporosis and MHT and exercise combined.</p><p><strong>Results: </strong>Initial searches identified 15,158 studies, narrowed to 20 meeting the inclusion criteria. MHT and exercise are effective in preserving BMD in menopausal women. Combined estrogen and progesterone MHT is more effective than estrogen-only, with studies suggesting that MHT prescribed at low doses for longer durations more effectively preserves BMD. Resistance training (RT) completed 2-3 days per week at a moderate-to-high intensity combined with impact activity completed at a minimum of 3 days per week is optimal for improving BMD in menopausal women, while low-impact exercises provide supplemental benefits. Combining MHT with exercise enhances BMD more than either alone.</p><p><strong>Conclusion: </strong>This review highlights that combining MHT and structured exercise is most effective for enhancing BMD in menopausal women. Given certain safety considerations surrounding MHT in some women, exercise remains a cornerstone for the prevention and management of osteoporosis as well as for promoting overall wellness.</p>","PeriodicalId":73103,"journal":{"name":"Frontiers in reproductive health","volume":"7 ","pages":"1542746"},"PeriodicalIF":2.3,"publicationDate":"2025-05-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12104296/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144152524","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Editorial: Cervical cancer awareness - volume I: screening, vaccines, and prevention. 社论:宫颈癌认识-第一卷:筛查、疫苗和预防。
IF 2.3
Frontiers in reproductive health Pub Date : 2025-05-12 eCollection Date: 2025-01-01 DOI: 10.3389/frph.2025.1579018
Anayawa Nyambe, Mwansa Ketty Lubeya
{"title":"Editorial: Cervical cancer awareness - volume I: screening, vaccines, and prevention.","authors":"Anayawa Nyambe, Mwansa Ketty Lubeya","doi":"10.3389/frph.2025.1579018","DOIUrl":"https://doi.org/10.3389/frph.2025.1579018","url":null,"abstract":"","PeriodicalId":73103,"journal":{"name":"Frontiers in reproductive health","volume":"7 ","pages":"1579018"},"PeriodicalIF":2.3,"publicationDate":"2025-05-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12104251/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144152521","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Unlocking the potential of embryos: insight of systematic review and meta-analysis into laser-assisted hatching's role in conquering recurrent implantation failure. 解锁胚胎的潜力:激光辅助孵化在克服复发性植入失败中的作用的系统回顾和荟萃分析的见解。
IF 2.3
Frontiers in reproductive health Pub Date : 2025-05-09 eCollection Date: 2025-01-01 DOI: 10.3389/frph.2025.1581529
Tingting Du, Yang Ma, Zanche Huang, Xiaoxuan Zhao, Qin Zhang, Ning Ren
{"title":"Unlocking the potential of embryos: insight of systematic review and meta-analysis into laser-assisted hatching's role in conquering recurrent implantation failure.","authors":"Tingting Du, Yang Ma, Zanche Huang, Xiaoxuan Zhao, Qin Zhang, Ning Ren","doi":"10.3389/frph.2025.1581529","DOIUrl":"10.3389/frph.2025.1581529","url":null,"abstract":"<p><strong>Introduction: </strong>The journey of assisted reproductive technology (ART) for couples facing recurrent implantation failure (RIF) is fraught with emotional and physical challenges. RIF, often characterized by the failure of high-quality embryos to implant after multiple ART cycles, has directed attention towards interventions like laser-assisted hatching (LAH). However, discrepancies in the literature necessitate a comprehensive review of LAH's efficacy and safety.</p><p><strong>Materials and methods: </strong>Following a thorough search of PubMed, Embase, Cochrane, and Web of Science databases up to November 2023, retrospective studies or RCT were considered for inclusion. Summary effect sizes [odds ratio (OR) or risk ratio (RR) with 95% confidence interval (CI)] were calculated for each outcome.</p><p><strong>Results and conclusion: </strong>Eight studies comprising 2,634 patients were included. LAH significantly improved implantation rates (OR: 1.26, 95% CI: 1.05-1.51). Clinical pregnancy rates increased in patients who had fresh embryos transferred (OR: 1.29, 95% CI: 1.05-1.58). Notably, LAH was associated with higher miscarriage rates in frozen embryo transfers (OR: 1.45, 95% CI: 1.04-2.02). No significant increase in ectopic or multiple pregnancy rates was observed. For patients with RIF, especially older women, LAH presents a potential avenue to improve implantation. Its impact on clinical pregnancy rates is less substantial. However, its impact on final live birth rates and the increased miscarriage risk in frozen transfers necessitate a cautious and individualized approach. The technique's safety, while generally upheld, requires careful application and consideration of the specific challenges RIF patients face. <b>Systematic Review Registration:</b> https://www.crd.york.ac.uk/PROSPERO/view/CRD42024497329, PROSPERO (CRD42024497329).</p>","PeriodicalId":73103,"journal":{"name":"Frontiers in reproductive health","volume":"7 ","pages":"1581529"},"PeriodicalIF":2.3,"publicationDate":"2025-05-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12098289/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144144774","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Efficacy of a cluster randomized controlled parental HIV disclosure intervention trial among parents living with HIV in China: evaluation based on the health action process approach. 中国艾滋病毒携带者父母艾滋病信息披露干预试验的聚类随机对照疗效:基于健康行动过程方法的评价
IF 2.3
Frontiers in reproductive health Pub Date : 2025-05-09 eCollection Date: 2025-01-01 DOI: 10.3389/frph.2025.1499481
Xiaoming Li, Ran Zhang, Wendi Da, Yuejiao Zhou, Zhiyong Shen, Shan Qiao
{"title":"Efficacy of a cluster randomized controlled parental HIV disclosure intervention trial among parents living with HIV in China: evaluation based on the health action process approach.","authors":"Xiaoming Li, Ran Zhang, Wendi Da, Yuejiao Zhou, Zhiyong Shen, Shan Qiao","doi":"10.3389/frph.2025.1499481","DOIUrl":"10.3389/frph.2025.1499481","url":null,"abstract":"<p><strong>Introduction: </strong>Parents living with HIV (PLH) face psychosocial challenges, including disclosing their HIV status to their children. Parental HIV disclosure is critical for reducing stigma, improving psychosocial well-being, and enhancing family cohesion. This study employed the Health Action Process Approach (HAPA) to assess the efficacy of a theory-based intervention aimed at facilitating HIV disclosure among PLH with children aged 6-15 in Guangxi, China.</p><p><strong>Method: </strong>Data from a randomized controlled trial involving 791 PLH were analyzed using a multigroup first-order manifest Markov Chain model to investigate transitions through the pre-intention, intention, and action stages over two follow-up periods (6 and 12 months).</p><p><strong>Results: </strong>The intervention significantly facilitated progression from pre-intention to action (OR = 3.43; 95% CI: 1.17, 10.01) but did not affect the transition from pre-intention to intention (OR = 1.02; 95% CI: 0.47, 2.20) or influence movement within the intention stage.</p><p><strong>Discussion: </strong>These findings suggest the need for stage-specific interventions to enhance disclosure practices. Future research should focus on identifying psychosocial predictors of disclosure and adapt interventions to the distinct stages of the disclosure decision-making process.</p>","PeriodicalId":73103,"journal":{"name":"Frontiers in reproductive health","volume":"7 ","pages":"1499481"},"PeriodicalIF":2.3,"publicationDate":"2025-05-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12098564/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144144771","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Healthcare workers' attitudes and factors affecting provision of sexual and reproductive health services to adolescents in refugee settlements, Western Uganda. 保健工作者的态度和影响向乌干达西部难民定居点的青少年提供性健康和生殖健康服务的因素。
IF 2.3
Frontiers in reproductive health Pub Date : 2025-05-08 eCollection Date: 2025-01-01 DOI: 10.3389/frph.2025.1498305
Simon Binezero Mambo, Moazzam Mohiuddin Lodhi, Isa Asiimwe, Gloria Neema Bizimana, Amos M'yisa Makelele, Solomom Adomi Mbina, Mathew Chibunna Igwe, Umar Ibrahim
{"title":"Healthcare workers' attitudes and factors affecting provision of sexual and reproductive health services to adolescents in refugee settlements, Western Uganda.","authors":"Simon Binezero Mambo, Moazzam Mohiuddin Lodhi, Isa Asiimwe, Gloria Neema Bizimana, Amos M'yisa Makelele, Solomom Adomi Mbina, Mathew Chibunna Igwe, Umar Ibrahim","doi":"10.3389/frph.2025.1498305","DOIUrl":"10.3389/frph.2025.1498305","url":null,"abstract":"<p><strong>Background: </strong>Provision of sexual and reproductive health services has an important impact on the adolescents standard of life. Healthcare workers interactions with clients has been highlighted as one of the main barriers keeping adolescents from seeking sexual and reproductive health services. This study aimed to assess the Healthcare workers' attitudes and factors affecting provision of sexual and reproductive health services in the Nakivale, Kyaka II, and Rwamwanja refugee settlements.</p><p><strong>Methods: </strong>This was a cross-sectional quantitative study in which healthcare workers from public and private health facilities refugee communities in south-western Uganda responded to a questionnaire. Binary logistic regression was done to assess the baseline characteristics associated with provision of these services using SPSS version 26.</p><p><strong>Results: </strong>Of the 386 medical professionals enrolled, 194(50.3%) were females with a mean age of 30.9 years (SD = 6.9). The services that were most commonly offered were contraception counselling/provision (81.3%) and comprehensive sexuality education provision (75.1%). The least offered services were safe abortion care (40.9%). The good attitudes were highest towards comprehensive sexuality education and antenatal, intrapartum plus postnatal care while the bad attitudes were highest toward safe abortion care. Residence, designation and type of facility had a significant association with offering of the different services (<i>P</i> < 0.05 for all at multivariate level of analysis). Being from rural area was positively associated with ASRH services (cOR = 2.685, 95% CI = 1.414-5.098). Being a nurse was associated with reduced provision of services as compared to being a counselor (cOR = 0.295, 95% CI = 099-0.882). Government facilities were more likely to offer adolescent sexual and reproductive health services compared to private facilities (cOR = 2.155, 95% CI = 1.169-4.075).</p><p><strong>Conclusion: </strong>In this study, majority of the study participants had a good attitude towards comprehensive sexuality education provision and antenatal, intrapartum and postnatal care while the bad attitudes were highest toward safe abortion care. More efforts are still required toward provision of safe abortion care and harmful traditional practices prevention. This will be achieved by providing training which will be vital in improving knowledge and attitude toward these services. The training should be more focused on the older professionals and non-councilors.</p>","PeriodicalId":73103,"journal":{"name":"Frontiers in reproductive health","volume":"7 ","pages":"1498305"},"PeriodicalIF":2.3,"publicationDate":"2025-05-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12096846/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144129689","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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