Frontiers in fungal biology最新文献

New insights into carbon metabolism in Spathaspora passalidarum for second-generation ethanol production. passalidarum碳代谢对第二代乙醇生产的新认识。

IF 3.8

Frontiers in fungal biology Pub Date : 2025-09-19 eCollection Date: 2025-01-01 DOI: 10.3389/ffunb.2025.1657121

Sofía Racca, Rodrigo J Leonardi, Raúl N Comelli

{"title":"New insights into carbon metabolism in Spathaspora passalidarum for second-generation ethanol production.","authors":"Sofía Racca, Rodrigo J Leonardi, Raúl N Comelli","doi":"10.3389/ffunb.2025.1657121","DOIUrl":"10.3389/ffunb.2025.1657121","url":null,"abstract":"Bioethanol is a sustainable, low-impact energy source with the potential to reduce or even replace fossil fuel consumption. Second-generation (2G) bioethanol exploits lignocellulosic agro-industrial residues, contributing to circular economy strategies by valorizing these waste streams. However, conventional Saccharomyces cerevisiae strains are unable to efficiently metabolize the pentose sugars abundant in lignocellulose, prompting growing interest in non-conventional yeasts such as Spathaspora passalidarum. This species, recognized for its innate ability to assimilate pentoses, remains underexplored, particularly regarding its metabolic performance in mixed-sugar environments containing hexoses, pentoses, and disaccharides. Our results demonstrate that S. passalidarum's xylose metabolism is strongly inhibited by pulses of hexoses such as glucose, galactose, and mannose, as well as by the disaccharide maltose. Notably, inhibition was also triggered by the non-metabolizable glucose analog 2-deoxyglucose (2DG), indicating that the regulatory signal originates during the early stages of glucose uptake into the cytosol rather than from downstream glycolytic pathways. In contrast, xylose metabolism was prioritized over fructose and sucrose. Furthermore, S. passalidarum was able to metabolize arabinose and glycerol, although these pathways favored biomass production through oxygen-dependent processes. Arabinose could be co-metabolized with xylose, but its assimilation was markedly suppressed in the presence of glucose. Collectively, these findings provide new insights into the metabolic regulation of S. passalidarum and highlight its potential role in the design of robust strategies for 2G bioethanol production.","PeriodicalId":73084,"journal":{"name":"Frontiers in fungal biology","volume":"6 ","pages":"1657121"},"PeriodicalIF":3.8,"publicationDate":"2025-09-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12491191/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145234339","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Microbial communities from distinct Vitis species shape volatile profiles of fermenting juices while preserving varietal typicity. 来自不同葡萄品种的微生物群落在保持品种典型的同时塑造了发酵果汁的挥发性特征。

IF 3.8

Frontiers in fungal biology Pub Date : 2025-09-18 eCollection Date: 2025-01-01 DOI: 10.3389/ffunb.2025.1643880

María Laura Raymond Eder, Laura Fariña, Francisco Carrau, Alberto Luis Rosa

{"title":"Microbial communities from distinct Vitis species shape volatile profiles of fermenting juices while preserving varietal typicity.","authors":"María Laura Raymond Eder, Laura Fariña, Francisco Carrau, Alberto Luis Rosa","doi":"10.3389/ffunb.2025.1643880","DOIUrl":"10.3389/ffunb.2025.1643880","url":null,"abstract":"Spontaneously fermenting grape juices represent complex ecosystems resulting from the dynamic interaction between the unique characteristics of a grape varietal and its indigenous associated microbiota. The extent to which specific grape variety volatile compounds versus microbially derived ones shape wine identity remains incompletely understood. In this work, we explored this issue by characterizing the volatile compound profiles at early stages of fermentation of the highly aromatic Isabella (V. labrusca L.) grape juice, conducted by native microbial communities prepared from either Isabella (homologous fermentation) or Malbec (V. vinifera L., heterologous fermentation) grapes. Results revealed that microbial starters derived from V. labrusca L. and V. vinifera L. markedly influenced the volatile profiles of the resulting fermented Isabella grape juices. Joint analysis of volatile profiles from Malbec and Isabella juices fermented with the same set of Vitis-specific microbial communities showed that, despite the strong influence of the microbial consortia, the fermented juices retained traits consistent with their original grape varietal identity. Characterization and identification of cultivable yeast species in these homologous and heterologous fermentations of Isabella grape juice showed H. uvarum, H. opuntiae, and S. bacillaris as dominant species in Malbec and Isabella microbial ecosystems. Our results highlight the potential of this innovative experimental approach to examine the relative roles of microbial communities and grape varietals in shaping wine identity. Moreover, they show that different Vitis-specific microbiota can distinctly influence the volatile profiles of a fermenting grape juice without altering its varietal identity.","PeriodicalId":73084,"journal":{"name":"Frontiers in fungal biology","volume":"6 ","pages":"1643880"},"PeriodicalIF":3.8,"publicationDate":"2025-09-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12489950/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145234240","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Roles of non-specific lipid transfer proteins in plant defense: structural and functional perspectives. 非特异性脂质转移蛋白在植物防御中的作用：结构和功能观点。

IF 3.8

Frontiers in fungal biology Pub Date : 2025-09-16 eCollection Date: 2025-01-01 DOI: 10.3389/ffunb.2025.1640465

John E McLaughlin, Nilgun E Tumer

{"title":"Roles of non-specific lipid transfer proteins in plant defense: structural and functional perspectives.","authors":"John E McLaughlin, Nilgun E Tumer","doi":"10.3389/ffunb.2025.1640465","DOIUrl":"10.3389/ffunb.2025.1640465","url":null,"abstract":"Non-specific lipid transfer proteins (nsLTPs) are vital and versatile components of plant cellular systems. They are characterized by a conserved eight-cysteine motif and are increasingly recognized for their dual roles in direct defense and stress modulation. nsLTPs serve critical structural and signaling functions in plant immunity. In contrast, other lipid transfer proteins, which lack the conserved cysteine motif, are primarily localized at membrane contact sites, specialized inter-organelle junctions that act as central hubs for lipid trafficking and signaling. This review explores the diverse roles of nsLTPs from structural, functional, and evolutionary perspectives, and examines current classification methodologies for the plant nsLTP superfamily. Functionally, nsLTPs contribute to the formation of protective barriers by transporting cutin monomers and other lipids, while also possessing lipid-specific antimicrobial properties that disrupt pathogen membranes. They support redox balance by scavenging reactive oxygen species, thereby minimizing oxidative stress. Additionally, nsLTPs are involved in defense signaling by transporting lipid-derived molecules essential to systemic acquired resistance. Their structural adaptability enables binding to a wide range of lipid species, underpinning their involvement in cuticle integrity, immune responses, and abiotic stress tolerance. These attributes position nsLTPs as promising targets for engineering durable, broad-spectrum disease resistance in crops. However, significant knowledge gaps remain regarding their structure-function relationships, lipid transport mechanisms, and roles in defense signaling and pathogen resistance. Addressing these challenges through advanced molecular and genetic tools could unlock the potential of nsLTPs to enhance crop resilience and contribute significantly to global food security.","PeriodicalId":73084,"journal":{"name":"Frontiers in fungal biology","volume":"6 ","pages":"1640465"},"PeriodicalIF":3.8,"publicationDate":"2025-09-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12480973/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145208135","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Peritoneal dialysis-related peritonitis caused by Fusarium: a case report and literature review. 镰孢菌所致腹膜透析相关性腹膜炎1例报告并文献复习。

IF 3.8

Frontiers in fungal biology Pub Date : 2025-09-16 eCollection Date: 2025-01-01 DOI: 10.3389/ffunb.2025.1637498

Qin Peng, Wenfeng Wu, Lirong Deng, Huanyue Tong, Huiyi Wu

引用次数: 0

Nanotechnology for fungal pathogen control in crops: innovations, public health impacts, and disease prevention. 纳米技术用于作物真菌病原体控制：创新、公共卫生影响和疾病预防。

IF 3.8

Frontiers in fungal biology Pub Date : 2025-09-01 eCollection Date: 2025-01-01 DOI: 10.3389/ffunb.2025.1653214

Matthew Chidozie Ogwu, Sylvester Chibueze Izah

{"title":"Nanotechnology for fungal pathogen control in crops: innovations, public health impacts, and disease prevention.","authors":"Matthew Chidozie Ogwu, Sylvester Chibueze Izah","doi":"10.3389/ffunb.2025.1653214","DOIUrl":"10.3389/ffunb.2025.1653214","url":null,"abstract":"Fungal pathogens continue to devastate global agriculture, causing significant crop losses, compromising food security, and posing emerging threats to public health. This paper critically examines the revolutionary role of nanotechnology-driven innovations in combating fungal diseases in crops, offering an integrative framework that bridges plant health, environmental sustainability, and human well-being. We synthesize recent advancements in agricultural nanomaterials, including silver, zinc oxide, and copper oxide nanoparticles, as well as green-synthesized nanoformulations. We examine their antifungal mechanisms, including membrane disruption, induction of oxidative stress, targeted delivery, and inhibition of spore germination. The review highlights how nanosensors can facilitate early detection of pathogens, while nano-enabled packaging and innovative delivery systems prevent post-harvest contamination and extend shelf life. Crucially, we underscore the public health benefits of reduced chemical pesticide use, lowered mycotoxin exposure, and the potential for mitigating antimicrobial resistance. The paper advances the discourse on environmentally responsible, high-precision disease control strategies in agriculture by linking nanotechnology to broader sustainability goals. Furthermore, we identify key challenges, including regulatory ambiguity, ecotoxicological concerns, and barriers to equitable adoption, especially among smallholder farmers in the Global South. This paper contributes a forward-looking agenda for integrating nanotechnology into holistic pest management systems through inclusive policies, interdisciplinary research, and stakeholder-driven implementation pathways. Overall, this review positions nanotechnology as a transformative tool in reengineering crop protection paradigms that align innovation with sustainability, resilience, and public health imperatives in the face of escalating global challenges.","PeriodicalId":73084,"journal":{"name":"Frontiers in fungal biology","volume":"6 ","pages":"1653214"},"PeriodicalIF":3.8,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12434137/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145076658","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Regulation of melanin production in fungi. 真菌中黑色素生成的调节。

IF 3.8

Frontiers in fungal biology Pub Date : 2025-08-29 eCollection Date: 2025-01-01 DOI: 10.3389/ffunb.2025.1621764

Kamaldeep Chhoker, Georg Hausner, Steven D Harris

引用次数: 0

Extreme UV sensitivity of native Metarhizium spp. as potential biocontrol agent for False Codling Moth (Thaumatotibia leucotreta Meyrick) on chili pepper in Ghana. 加纳土生绿僵菌对辣椒的紫外线敏感性研究。

IF 3.8

Frontiers in fungal biology Pub Date : 2025-08-25 eCollection Date: 2025-01-01 DOI: 10.3389/ffunb.2025.1660692

Patricia Akua Sitsofe Nyahe, Vincent Yao Eziah, Laith Khalil Tawfeeq Al-Ani, Monica Akumyoungta, Candice Anne Coombes, Drauzio Eduardo Naretto Rangel, Alene Alder-Rangel, Dalia Sukmawati, Owusu Fordjour Aidoo, Mavis Agyeiwaa Acheampong

{"title":"Extreme UV sensitivity of native Metarhizium spp. as potential biocontrol agent for False Codling Moth (Thaumatotibia leucotreta Meyrick) on chili pepper in Ghana.","authors":"Patricia Akua Sitsofe Nyahe, Vincent Yao Eziah, Laith Khalil Tawfeeq Al-Ani, Monica Akumyoungta, Candice Anne Coombes, Drauzio Eduardo Naretto Rangel, Alene Alder-Rangel, Dalia Sukmawati, Owusu Fordjour Aidoo, Mavis Agyeiwaa Acheampong","doi":"10.3389/ffunb.2025.1660692","DOIUrl":"10.3389/ffunb.2025.1660692","url":null,"abstract":"Chili pepper exports from Ghana are subject to stringent chemical residue regulations in key export destinations. Consequently, microbial biopesticides are urgently needed to complement current nonchemical control options for key pests of chili pepper, particularly the phytosanitary insect, False Codling Moth (FCM). Thus, the search for native entomopathogenic fungi in Ghanaian farms was initiated in 2023. Seven Metarhizium isolates (UGSUHCI, UGJKCS9, UGJKCS10, UGAFMF8, UGAFM F12, UGNAKC1 and UGKAP1), obtained from agricultural soils in Ghana, showed high virulence against the soil-dwelling stages of FCM under laboratory conditions. To facilitate the selection of these virulent isolates for development into a mycoinsecticide for FCM, the UV sensitivity and virulence following UV exposure were investigated for all seven isolates in this study. All isolates exhibited extreme susceptibility to UV radiation in comparison to similar research. Exposure to simulated full-spectrum solar radiation at 0.6 W/m2 for 30 min reduced relative conidial germination by 28-40% 48 h following exposure, while 60 min exposure killed all isolates. High insect mortalities were recorded for four isolates, regardless of UV radiation. The findings suggest that an effective UV-protectant formulation could be required for success in the field against fruit and foliar pests of chili pepper, including those of FCM.","PeriodicalId":73084,"journal":{"name":"Frontiers in fungal biology","volume":"6 ","pages":"1660692"},"PeriodicalIF":3.8,"publicationDate":"2025-08-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12415697/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145030792","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The transcriptional coordination of functional gene clusters is dependent on multiple chromatin remodelers in a haploid strain of the budding yeast, Saccharomyces cerevisiae. 在单倍体芽殖酵母中，功能基因簇的转录协调依赖于多个染色质重塑子。

IF 3.8

Frontiers in fungal biology Pub Date : 2025-08-15 eCollection Date: 2025-01-01 DOI: 10.3389/ffunb.2025.1634150

Abtsam A Baadani, Gabrielle F Coon, Christopher Bui, Mary C Chidester, Reem S Eldabagh, James T Arnone

{"title":"The transcriptional coordination of functional gene clusters is dependent on multiple chromatin remodelers in a haploid strain of the budding yeast, Saccharomyces cerevisiae.","authors":"Abtsam A Baadani, Gabrielle F Coon, Christopher Bui, Mary C Chidester, Reem S Eldabagh, James T Arnone","doi":"10.3389/ffunb.2025.1634150","DOIUrl":"10.3389/ffunb.2025.1634150","url":null,"abstract":"The organization of functionally related gene families oftentimes exhibits a non-random genomic distribution as gene clusters that are prevalent throughout divergent eukaryotic organisms. The molecular and cellular functions of the gene families where clustering has been identified vary, and include those involved in basic metabolism, secondary metabolite biosynthesis, and large gene families (e.g. ribosomal proteins). Many of these gene families exhibit transcriptional coregulation, however the roles that clustering plays and the mechanism(s) underlying co-expression are currently understudied. A comprehensive characterization of these relationships would allow for a greater understanding of the implications of genetic editing and engineering to minimize undesired consequences. Here we report the impact of gene clustering and genomic positioning on the expression of large, coregulated gene families in a haploid strain of the budding yeast, Saccharomyces cerevisiae. Computational analysis identifies a significant and complex role for chromatin remodeling as a mechanism underlying cluster transcription. Functional dissection of the 'vitamin metabolic process', 'ribosome biogenesis', and 'ribosomal protein' gene families, characterized the roles for SNF2, JHD2, HIR2, EAF3, and yKU70 dependent chromatin remodeling during steady state transcription as well as the transcriptional response to glucose replenishment. Finally, mining and analysis of transcription profiles reveals significant transcriptional differences between the clustered and unclustered subsets within coregulated families under specific stressors.","PeriodicalId":73084,"journal":{"name":"Frontiers in fungal biology","volume":"6 ","pages":"1634150"},"PeriodicalIF":3.8,"publicationDate":"2025-08-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12394982/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144981085","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Multi-loci phylogeny reveals unexpected novelty of the Thelephora palmata complex (Thelephoraceae, Thelephorales) from China. 多位点系统发育揭示了中国掌象群（象科，象科）出人意料的新颖性。

IF 3.8

Frontiers in fungal biology Pub Date : 2025-08-14 eCollection Date: 2025-01-01 DOI: 10.3389/ffunb.2025.1599905

Tai-Jie Yu, Rou Xue, Lin-Jie Su, Jia Li, Xing Xia, Chang Xu, Han-Chi Lei, Wen-Hao Zhang, Jing Ma, Hong-Yan Huang, Xiu-Juan Li, Yu-Xian Gao, Zhi-Xiang Zhang, Li Li, Guo-Li Zhang, Li-Ping Tang

{"title":"Multi-loci phylogeny reveals unexpected novelty of the Thelephora palmata complex (Thelephoraceae, Thelephorales) from China.","authors":"Tai-Jie Yu, Rou Xue, Lin-Jie Su, Jia Li, Xing Xia, Chang Xu, Han-Chi Lei, Wen-Hao Zhang, Jing Ma, Hong-Yan Huang, Xiu-Juan Li, Yu-Xian Gao, Zhi-Xiang Zhang, Li Li, Guo-Li Zhang, Li-Ping Tang","doi":"10.3389/ffunb.2025.1599905","DOIUrl":"10.3389/ffunb.2025.1599905","url":null,"abstract":"Thelephora palmata is a well-known species morphologically characterized by coralloid and leathery basidiomata with numerous fuscous purple to blackish-brown branches. It was once considered to exhibit a wide ecological range and distribution area. However, comprehensive phylogenetic analysis based on four loci (ITS, nrLSU, rpb2, and nrSSU) revealed that T. palmata sensu lato represents a species complex consisting of at least 12 cryptic taxa, with a biogeographic distribution pattern bounded by geographic regions: Asia, Eurasia, Europe, and North America. In this study, we proposed eight new taxa based on available specimens. Of these, seven new species and one forma from China were described here based on phylogenetic analyses, morphological examinations, and environmental niche comparisons, viz., T. apiculata, T. cornu-damae, T. densa, T. esculenta, T. fuscidula, T. sinopalmata, T. truncicola, and T. truncicola f. pallescens.","PeriodicalId":73084,"journal":{"name":"Frontiers in fungal biology","volume":"6 ","pages":"1599905"},"PeriodicalIF":3.8,"publicationDate":"2025-08-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12391122/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144981136","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Orthrus: a Pumilio-family gene involved in fruiting body and dark stipe development in Coprinopsis cinerea. 直柄：一个参与铜opsis cinerea子实体和暗柄发育的矮穗家族基因。

IF 3.8

Frontiers in fungal biology Pub Date : 2025-07-30 eCollection Date: 2025-01-01 DOI: 10.3389/ffunb.2025.1633301

Benedek Szathmári, Balázs Bálint, Botond Hegedüs, Máté Virágh, Zhihao Hou, Xiao-Bin Liu, Hongli Wu, Csenge Földi, Julien Gagneur, Johann Promeuschel, Árpád Csernetics, László G Nagy

{"title":"Orthrus: a Pumilio-family gene involved in fruiting body and dark stipe development in Coprinopsis cinerea.","authors":"Benedek Szathmári, Balázs Bálint, Botond Hegedüs, Máté Virágh, Zhihao Hou, Xiao-Bin Liu, Hongli Wu, Csenge Földi, Julien Gagneur, Johann Promeuschel, Árpád Csernetics, László G Nagy","doi":"10.3389/ffunb.2025.1633301","DOIUrl":"10.3389/ffunb.2025.1633301","url":null,"abstract":"Fruiting bodies of mushroom-forming fungi (Agaricomycetes) are complex multicellular structures whose formation is regulated by a developmental program that dynamically responds to environmental changes, such as light intensity. However, the genetic architecture and regulation of this developmental program are poorly known. Here, we characterize a novel Pumilio family gene, ort2, which influences fruiting body development, particularly the formation of dark stipes, a light-dependent alternative developmental trajectory. Phylogenetic analysis of this RNA-binding protein family in fungi revealed a distinct subfamily structure, with high conservation of each subfamily within Agaricomycetes. Reverse genetics experiments in the model species Coprinopsis cinerea revealed that ort2 disruptants produced fruiting bodies, but were deficient in dark stipe formation, whereas the overexpression mutants produced significantly more dark stipes. The gene was named after Orthrus, the two-headed dog of classical mythology, based on rare but reproducible branching fruiting body phenotypes observed upon overexpression. Our findings reveal fruiting-related functions for ort2, a novel conserved RNA-binding protein, and may serve as a novel entry point for understanding the molecular basis of dark stipe development.","PeriodicalId":73084,"journal":{"name":"Frontiers in fungal biology","volume":"6 ","pages":"1633301"},"PeriodicalIF":3.8,"publicationDate":"2025-07-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12344735/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144849919","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0