Advances In Anatomic Pathology最新文献_第2页

Mesenchymal Tumors of the Human Body: A Targeted Practical Review (Part II).

IF 5.1 2区医学

Advances In Anatomic Pathology Pub Date : 2025-03-01 Epub Date: 2025-02-19 DOI: 10.1097/PAP.0000000000000490

Andrew Rosenberg, Andre Pinto

引用次数: 0

Lipomatous Neoplasms of Soft Tissue: A Contemporary Review. 软组织脂肪瘤：当代回顾。

IF 5.1 2区医学

Advances In Anatomic Pathology Pub Date : 2025-03-01 Epub Date: 2024-10-22 DOI: 10.1097/PAP.0000000000000468

Kshitij Arora, Andrew E Rosenberg

引用次数: 0

Pediatric Mesenchymal Tumors. 儿童间充质肿瘤。

IF 5.1 2区医学

Advances In Anatomic Pathology Pub Date : 2025-03-01 Epub Date: 2024-12-11 DOI: 10.1097/PAP.0000000000000480

Omar Aljuboori, Ali G Saad

引用次数: 0

Updated Classification of Cutaneous Lymphoma.

IF 5.1 2区医学

Advances In Anatomic Pathology Pub Date : 2025-02-27 DOI: 10.1097/PAP.0000000000000487

John R Goodlad

{"title":"Updated Classification of Cutaneous Lymphoma.","authors":"John R Goodlad","doi":"10.1097/PAP.0000000000000487","DOIUrl":"https://doi.org/10.1097/PAP.0000000000000487","url":null,"abstract":"The International Consensus Classification (ICC) of myeloid and lymphoid neoplasms follows the precedent set in the Revised European-American lymphoma classification for modern lymphoma classifications by defining specific diseases on the basis of all the available morphologic, immunophenotypic, genetic, and clinical findings. Primary cutaneous lymphomas exhibit a broad range of clinical behavior ranging from lesions which spontaneously regress to those which run an aggressive, often fatal course. Accurate separation of entities is therefore essential for prognostication and to ensure appropriate treatment is administered. However, despite marked differences in clinical course, many subtypes of primary cutaneous lymphoma exhibit remarkably similar, often overlapping, and sometimes indistinguishable pathologic features. While molecular analysis has furthered our understanding of some of these disease entities, it does not yet facilitate robust distinction. Thus, clinical correlation retains a central role in both the diagnosis and classification of primary cutaneous lymphoma. This review aims to draw attention to problem areas in differential diagnosis and hopefully offer some practical suggestions for resolving difficult cases. It will also highlight recent advances in the field and discuss how they reinforce the current classification system and how they might impact of future classifications and treatment strategies.","PeriodicalId":7305,"journal":{"name":"Advances In Anatomic Pathology","volume":" ","pages":""},"PeriodicalIF":5.1,"publicationDate":"2025-02-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143603361","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Rare Liver Diseases With Near-Normal Histology: A Review Focusing on Metabolic, Storage, and Inclusion Disorders.

IF 5.1 2区医学

Advances In Anatomic Pathology Pub Date : 2025-02-17 DOI: 10.1097/PAP.0000000000000488

Xiaotang Du, Hanlin L Wang

{"title":"Rare Liver Diseases With Near-Normal Histology: A Review Focusing on Metabolic, Storage, and Inclusion Disorders.","authors":"Xiaotang Du, Hanlin L Wang","doi":"10.1097/PAP.0000000000000488","DOIUrl":"https://doi.org/10.1097/PAP.0000000000000488","url":null,"abstract":"Despite the growing availability of noninvasive and faster diagnostic modalities, biopsy remains an important tool in the diagnosis and management of liver diseases. However, it is not uncommon that liver biopsies reveal normal or near normal histologic findings in patients with abnormal liver biochemistries, elevated autoantibodies, clinical findings suggestive of portal hypertension, systemic autoimmune or inflammatory diseases, hepatomegaly, cirrhosis by imaging, or other indications. These scenarios present significant diagnostic challenges and are rarely discussed in detail in the literature or textbooks. This article aims to provide a comprehensive review of a group of selected rare liver diseases, with a focus on metabolic, storage and inclusion disorders, that may exhibit a near-normal histology on biopsy. By recognizing subtle histologic features and correlating with clinical history, laboratory results and imaging findings, it is often possible to narrow down the differential diagnosis. In many cases, this integrative approach can yield a definitive diagnosis, allowing for tailored treatment and better patient outcomes.","PeriodicalId":7305,"journal":{"name":"Advances In Anatomic Pathology","volume":" ","pages":""},"PeriodicalIF":5.1,"publicationDate":"2025-02-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143456464","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The Classification of Hematopoietic Neoplasms: The Why, How, and Who?

IF 5.1 2区医学

Advances In Anatomic Pathology Pub Date : 2025-02-11 DOI: 10.1097/PAP.0000000000000489

Daniel A Arber, James R Cook

引用次数: 0

The Diagnostic Spectrum of Myelodysplastic Syndromes and Acute Myeloid Leukemia.

IF 5.1 2区医学

Advances In Anatomic Pathology Pub Date : 2025-02-03 DOI: 10.1097/PAP.0000000000000485

Daniel A Arber, Attilio Orazi

{"title":"The Diagnostic Spectrum of Myelodysplastic Syndromes and Acute Myeloid Leukemia.","authors":"Daniel A Arber, Attilio Orazi","doi":"10.1097/PAP.0000000000000485","DOIUrl":"https://doi.org/10.1097/PAP.0000000000000485","url":null,"abstract":"The International Consensus Classification (ICC) of myelodysplastic syndromes (MDS) and acute myeloid leukemia (AML) expands on the work of prior classifications to refine the diagnostic criteria for MDS and AML and to identify specific genetic disease subtypes. This review summarizes the approach to the diagnosis of MDS and AML from the ICC perspective. For MDS, the significance of detecting mutations in SF3B1, usually associated with ring sideroblasts, as well as the poor prognosis of mutations of TP53 are now included. For AML, new genetic categories are included, and the classification now incorporates additional clinically significant gene mutations by recognizing AML with TP53 mutation and AML with mutations in genes associated with prior therapy or MDS. Finally, the new category of MDS/AML is introduced for adult patients without recurrent de novo genetic abnormalities with 10% to 19% peripheral blood or bone marrow blasts that allow for more treatment flexibility based on clinical findings. While the increase in genetic categories and changes in blast cell requirements can be confusing, a stepwise approach is provided to allow easy use of the classification.","PeriodicalId":7305,"journal":{"name":"Advances In Anatomic Pathology","volume":" ","pages":""},"PeriodicalIF":5.1,"publicationDate":"2025-02-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143078323","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Steatotic Liver Disease: Navigating Pathologic Features, Diagnostic Challenges, and Emerging Insights.

IF 5.1 2区医学

Advances In Anatomic Pathology Pub Date : 2025-01-17 DOI: 10.1097/PAP.0000000000000483

Jingjing Jiao, Xuchen Zhang

引用次数: 0

Diagnosis and Classification of Follicular Lymphoma and Related Entities.

IF 5.1 2区医学

Advances In Anatomic Pathology Pub Date : 2025-01-17 DOI: 10.1097/PAP.0000000000000481

Camille Laurent, James R Cook

引用次数: 0

Advances in the Classification of Aggressive B-cell Lymphomas. 侵袭性b细胞淋巴瘤分类研究进展。