Enfermedades infecciosas y microbiologia clinica (English ed.)最新文献

{"title":"The trade-off between speed and accuracy: immunochromatographic diagnosis of Clostridioides difficile.","authors":"Aina Mena Ribas","doi":"10.1016/j.eimce.2026.503250","DOIUrl":"https://doi.org/10.1016/j.eimce.2026.503250","url":null,"abstract":"","PeriodicalId":72916,"journal":{"name":"Enfermedades infecciosas y microbiologia clinica (English ed.)","volume":" ","pages":"503250"},"PeriodicalIF":0.0,"publicationDate":"2026-08-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148762933","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Case report: Myocarditis secondary to MPOX infection.","authors":"Mario Dávila Panzano, Adrián Alfonso Álvarez, María Del Mar Arcos Rueda, Elena Sendagorta Cudos","doi":"10.1016/j.eimce.2026.503262","DOIUrl":"https://doi.org/10.1016/j.eimce.2026.503262","url":null,"abstract":"","PeriodicalId":72916,"journal":{"name":"Enfermedades infecciosas y microbiologia clinica (English ed.)","volume":" ","pages":"503262"},"PeriodicalIF":0.0,"publicationDate":"2026-08-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148762552","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Bull-horn wound infected by Lacrimispora celerecrescens: First case reported.","authors":"Berta Requejo Baruque, Jesús E Guevara Osorio, Teresa Nebreda Mayoral, Silvia Rojo Rello","doi":"10.1016/j.eimce.2026.503260","DOIUrl":"https://doi.org/10.1016/j.eimce.2026.503260","url":null,"abstract":"","PeriodicalId":72916,"journal":{"name":"Enfermedades infecciosas y microbiologia clinica (English ed.)","volume":" ","pages":"503260"},"PeriodicalIF":0.0,"publicationDate":"2026-08-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148765456","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Rothia spp.: An unusual cause of infective endocarditis","authors":"Javier Martínez de Victoria Carazo,&nbsp;Antonio García-Chamón Boronat,&nbsp;Francisco Anguita Santos,&nbsp;Alberto Vázquez-Blanquiño,&nbsp;Andrés Luís Ruíz Sancho","doi":"10.1016/j.eimce.2026.503199","DOIUrl":"10.1016/j.eimce.2026.503199","url":null,"abstract":"<div><h3>Introduction</h3><div><em>Rothia</em> spp. are commensal organisms involved in serious infections such as infective endocarditis (IE). There is a significant lack of information regarding de clinical course and management of <em>Rothia</em> spp. IE in immunocompetent patients.</div></div><div><h3>Methods</h3><div>This study describes 11 cases of <em>Rothia</em> spp. bacteremia over a 10-year period in a secondary hospital, analyzing clinical, demographic, and microbiological data. True infection was defined based on clinical signs, microbiological criteria, and radiological evidence.</div></div><div><h3>Results</h3><div>Three cases (27.3%) were confirmed as true infections, all presenting as infective endocarditis. All three infections were caused by <em>Rothia mucilaginosa</em> in non-immunocompromised patients. Identified risk factors included type 2 diabetes, pre-existing valvular disease, prosthetic implants, and odontogenic foci. 100% of cases developed severe central nervous system complications. Total bacterial eradication without recurrence was achieved, and no acute valve surgery was required.</div></div><div><h3>Conclusions</h3><div><em>Rothia</em> spp. can cause true bacteremia and IE in non-immunocompromised patients. Time to positivity (TTP) and clinical correlation are fundamental to distinguish between true infection and contamination. Individualized shorter antibiotic regimens might be explored in selected cases, although conventional durations remain the standard due to the severity of complications.</div></div>","PeriodicalId":72916,"journal":{"name":"Enfermedades infecciosas y microbiologia clinica (English ed.)","volume":"44 7","pages":"Article 503199"},"PeriodicalIF":0.0,"publicationDate":"2026-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148651576","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Persistent generalized lymphadenopathy in a young woman: What is the diagnosis?","authors":"Burak Kizilcay,&nbsp;Yusuf Emre Ozdemir","doi":"10.1016/j.eimce.2026.503226","DOIUrl":"10.1016/j.eimce.2026.503226","url":null,"abstract":"","PeriodicalId":72916,"journal":{"name":"Enfermedades infecciosas y microbiologia clinica (English ed.)","volume":"44 7","pages":"Article 503226"},"PeriodicalIF":0.0,"publicationDate":"2026-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148355014","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Five years-real-world experience with FilmArray Pneumonia Plus Panel in the diagnosis of pneumonia in an intensive care unit in a tertiary hospital: Lights and shadows in pandemic and postpandemic COVID periods","authors":"Juan M. García-Lechuz,&nbsp;Antonina Arias,&nbsp;Pilar Alonso,&nbsp;David Badenas-Alzugaray,&nbsp;Victor Viñeta,&nbsp;Luis Claraco,&nbsp;Marta Gurpegui,&nbsp;Andrés Carrillo,&nbsp;Jesús Viñuelas","doi":"10.1016/j.eimce.2026.503107","DOIUrl":"10.1016/j.eimce.2026.503107","url":null,"abstract":"<div><h3>Introduction</h3><div>The main objective of the study is to evaluate the performance of the <em>FilmArray</em>® <em>Pneumonia Plus</em> (<em>FA-PP</em>) panel in critically ill patients with suspected pneumonia compared to conventional culture, in both pandemic and pospandemic periods, and its impact on therapeutic decision-making.</div></div><div><h3>Methods</h3><div>Observational study including 225 patients (314 samples) during COVID-19 pandemic and post-pandemic periods. FA-PP and culture results were compared assessing sensitivity (Se), specificity, predictive values, level of concordance between them and the impact on antibiotic prescription.</div></div><div><h3>Results</h3><div>FA-PP detected 133% more bacterial targets than culture and 48% more positive samples. Excluding off-panel bacteria, the panel showed high sensitivity of up to 100% in patients with pneumonia and a negative predictive value (NPV) of over 98%. In the post-pandemic period, the overall Se (78.6%) and Se in patients with pneumonia (81%), as well as the overall NPV and in pneumonia (94%), were higher than in the pandemic period, with significant differences (<em>p</em> <!-->&lt;<!--> <!-->0.05). Twenty-six per cent of pneumonia episodes involved bacteria not included in the panel. The positive concordance between the two tests was 72%. In 56% of cases with pneumonia, antibiotic was modified after the results. During the pandemic period, the panel served to modify treatment towards initiation or escalation.</div></div><div><h3>Conclusions</h3><div>The FA-PP is a valuable tool for optimizing the diagnosis and management of pneumonia in the ICU, with a clinical impact on the appropriateness of antibiotic treatment. There were differences in the impact of the panel between the pandemic and post-pandemic periods.</div></div>","PeriodicalId":72916,"journal":{"name":"Enfermedades infecciosas y microbiologia clinica (English ed.)","volume":"44 7","pages":"Article 503107"},"PeriodicalIF":0.0,"publicationDate":"2026-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148651631","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Solitary umbilicated lesion on the finger: An atypical presentation","authors":"Filipe Monteiro,&nbsp;Inês Tribolet-Abreu,&nbsp;Gustavo Almeida-Silva,&nbsp;Sónia Fernandes,&nbsp;Joana Antunes","doi":"10.1016/j.eimce.2026.503220","DOIUrl":"10.1016/j.eimce.2026.503220","url":null,"abstract":"","PeriodicalId":72916,"journal":{"name":"Enfermedades infecciosas y microbiologia clinica (English ed.)","volume":"44 7","pages":"Article 503220"},"PeriodicalIF":0.0,"publicationDate":"2026-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148651632","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Can I rely on the negativity of my liquid media for mycobacteria (BACTEC™ MGIT™)?","authors":"Ramiro López-Medrano,&nbsp;Isabel Burgos-Asurmendi,&nbsp;Octavio Rivero-Lezcano","doi":"10.1016/j.eimce.2026.503221","DOIUrl":"10.1016/j.eimce.2026.503221","url":null,"abstract":"<div><div>Automated liquid media have represented a major advance in the culture of mycobacteria, limiting the use of solid media and even removing them. In this study, we investigated whether the Bactec MGIT automated system fails to detect mycobacteria and their possible causes. Over a period of three years (2023–2025), a total of 9.111 cultures for mycobacteria were performed using automated liquid media (Bactec MGIT). All negative tubes were inspected visually, and those with suspected growth were stained with Ziehl-Neelsen. Those that were positive were reinoculated, and the grown colonies were identified by molecular detection (Xpert MTB/RIF) and proteomics (MALDI-TOF). A total of 0.2% of all tubes incubated in this system were considered a detection failure, representing 11.1% of all mycobacterial isolates. A total of 22 cases were recorded, of which 8 (36.3%) were identified as <em>M. tuberculosis</em> complex (MTC) and the remaining 14 as NTMs (63.6%): <em>M. lentiflavum, M. gordonae</em>, <em>M. avium, M. abscessus subsp. abscessus, M. chelonae, M. mageritense, M. celatum, and M. paragordonae</em>. In 6 out of 8 patients who were undergoing anti-tuberculosis treatment an MTC species was isolated. When an MNT was isolated, only those isolated in non-respiratory samples were considered clinically significant. A final visual inspection of these negative tubes in the absence of molecular techniques, would be the only way to detect these cases.</div></div>","PeriodicalId":72916,"journal":{"name":"Enfermedades infecciosas y microbiologia clinica (English ed.)","volume":"44 7","pages":"Article 503221"},"PeriodicalIF":0.0,"publicationDate":"2026-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148407270","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Measles microbiological diagnosis in vaccinated persons: new times, new challenges","authors":"Ana Garrido Buenache,&nbsp;Fernando Martín Martínez,&nbsp;Aurora Fernández García,&nbsp;Juan Carlos Sanz Moreno","doi":"10.1016/j.eimce.2026.503204","DOIUrl":"10.1016/j.eimce.2026.503204","url":null,"abstract":"","PeriodicalId":72916,"journal":{"name":"Enfermedades infecciosas y microbiologia clinica (English ed.)","volume":"44 7","pages":"Article 503204"},"PeriodicalIF":0.0,"publicationDate":"2026-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148240746","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Prosthetic knee joint infection due to Streptococcus canis","authors":"Altea Martínez García,&nbsp;Óscar Pérez Olaso,&nbsp;Rosa González Pellicer,&nbsp;Juan J. Camarena Miñana","doi":"10.1016/j.eimce.2026.503217","DOIUrl":"10.1016/j.eimce.2026.503217","url":null,"abstract":"","PeriodicalId":72916,"journal":{"name":"Enfermedades infecciosas y microbiologia clinica (English ed.)","volume":"44 7","pages":"Article 503217"},"PeriodicalIF":0.0,"publicationDate":"2026-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148407246","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}