Enfermedades infecciosas y microbiologia clinica (English ed.)最新文献

{"title":"Norovirus GII.17 gastroenteritis outbreak in a nursing home.","authors":"Paula Martín Bazarra, Óscar Esparcia Rodríguez, Angélica Gómez Martínez, Regina Azancot Carballo, Caridad Sainz de Baranda Camino, Nerea García Ibáñez, María Dolores Fernández García, Rafael Carranza González","doi":"10.1016/j.eimce.2025.02.004","DOIUrl":"https://doi.org/10.1016/j.eimce.2025.02.004","url":null,"abstract":"<p><strong>Introduction: </strong>Gastrointestinal norovirus infections are highly prevalent, causing outbreaks especially in institutions such as nursing homes. We describe an outbreak caused by an emerging norovirus genotype.</p><p><strong>Material and methods: </strong>We defined a case as a resident or worker of the centre with clinical signs and symptoms of AGE from 14 to 29 May 2022, with no underlying pathology to justify it. A clinical-epidemiological survey was carried out and stool samples were collected from patients with diarrhoea at the time of the study. Virological analysis was performed at the Microbiology Department of our hospital by antigenic detection (Certest®, Biotec SL) and/or multiplex PCR (AllplexTM GI-Virus Assay, Seegene®). Viral genotyping by sequencing was performed by the Centro Nacional de Microbiología (CNM).</p><p><strong>Results: </strong>The outbreak totaled 114 cases (99 residents, 15 workers), extending over 16 days. The most frequent symptoms were vomiting and diarrhoea. The overall attack rate was 30.8% (in workers 12.7%). Cases increased rapidly in the first 48h, falling progressively over successive days. Food contamination was ruled out, with person-to-person transmission being the most likely. Those affected improved clinically in less than 72h, with no deaths. We tested 14 samples from residents, which were positive for norovirus GII. The CNM received 8 samples, detecting norovirus genogroup GII, genotype 17 [P17] in 6.</p><p><strong>Conclusions: </strong>Outbreaks of norovirus GEA in nursing homes can affect numerous users. In our case, norovirus genotype GII.17 was the aetiological agent, confirming its widespread dissemination in the last decade worldwide.</p>","PeriodicalId":72916,"journal":{"name":"Enfermedades infecciosas y microbiologia clinica (English ed.)","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-02-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143538115","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Recovery of the increasing pattern of sexually transmitted infections (STI) after the COVID-19 pandemic: The case of gonorrhea in Catalonia, Spain.","authors":"Evelin López-Corbeto, Julia Valera Paloma, Marcos Montoro Fernández, Rossie Lugo Colón, Laura Clotet Romero, Víctor Guadalupe Fernandez, Pilar Ciruela Navas, Jordi Casabona Barbara","doi":"10.1016/j.eimce.2025.02.001","DOIUrl":"https://doi.org/10.1016/j.eimce.2025.02.001","url":null,"abstract":"<p><strong>Introduction: </strong>Sexually transmitted infections (STI) have shown a sustained increase in recent years. Changes in epidemiological patterns highlight the need to adapt public health strategies for their prevention and control. The objective of this study is to describe the trend of reported gonorrhea cases in Catalonia (Spain) from 2017 to 2023 and to compare the epidemiological pattern of reported cases before, during, and after the COVID-19 pandemic.</p><p><strong>Methods: </strong>Descriptive analysis of reported gonorrhea cases in Catalonia among individuals aged ≥ 14 years between 2017 and 2023. Incidence rates (IR) were calculated overall and by sex, age, and origin. A descriptive analysis was conducted to compare reported cases across the pre-pandemic (2017-2019), pandemic (2020), and post-pandemic (2021-2023) periods.</p><p><strong>Results: </strong>The IR of gonorrhea showed an average increase of 32.9% between 2017-2019 and 37.9% between 2021-2023, reaching 164.0 cases per 100,000 inhabitants in 2023. During the pandemic, there was an increase in the proportion of cases among MSM (13.3%), alcohol use (40.0%), having ≥ 6 sexual partners (30.5%), and new sexual partners (74.3%). In the post-pandemic period, the highest percentage increase was observed in women (115.7%), Spanish nationals (124.9%), cases reported in sexual and reproductive health units (30.9%), symptomatic cases (58.0%), and reinfections (33.0%). Additionally, there was a decrease in the average age, particularly among women, in contact tracing studies (13.1%), and in antibiotic resistance.</p><p><strong>Conclusions: </strong>Gonorrhea continues to rise, especially among young people and women. Strengthening its visibility and prioritizing it in STI prevention and control programs is crucial to mitigate its impact on public health.</p>","PeriodicalId":72916,"journal":{"name":"Enfermedades infecciosas y microbiologia clinica (English ed.)","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-02-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143484918","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Dermatitis caused by tiny invaders.","authors":"Karol Nicole Sabas Ortega, José Asensio Gómez, Isabel Zárate Tejero, Javier Sánchez Bernal","doi":"10.1016/j.eimce.2025.02.002","DOIUrl":"https://doi.org/10.1016/j.eimce.2025.02.002","url":null,"abstract":"","PeriodicalId":72916,"journal":{"name":"Enfermedades infecciosas y microbiologia clinica (English ed.)","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-02-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143477284","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Fever and skin lesions in a patient undergoing chemotherapy.","authors":"José González Fernández, Alejandro Tomás Esteban Escudero, Mar García García","doi":"10.1016/j.eimce.2025.01.001","DOIUrl":"https://doi.org/10.1016/j.eimce.2025.01.001","url":null,"abstract":"","PeriodicalId":72916,"journal":{"name":"Enfermedades infecciosas y microbiologia clinica (English ed.)","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-02-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143371448","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Impact of the passive immunization campaign with nirsevimab in 2023-24 in Castellón. Final results.","authors":"Eulalia Gregori-García, Juan Carlos Gascó-Laborda, Lledó Lluch-Bacas, Oscar Pérez-Olaso, Iris Gómez-Alfaro, Juan B Bellido-Blasco","doi":"10.1016/j.eimce.2025.01.006","DOIUrl":"https://doi.org/10.1016/j.eimce.2025.01.006","url":null,"abstract":"<p><strong>Introduction: </strong>In the 2023-2024 season, systematic immunization with the monoclonal antibody nirsevimab was recommended in Spain. The impact that this immunization program had on the target population of the program is analyzed.</p><p><strong>Methods: </strong>Pre-post ecological study comparing 2023-24 vs 2022-23 season. The variation in incidence is described by age groups (0-5, 6-11 and 12-59 months) and hospitalization. Incidence rates were calculated and relative risks (RR) were estimated for each group.</p><p><strong>Results: </strong>The results were very heterogeneous depending on the age group. In children 0-5 months old the RR was 0.16 (0.10-0.25); in those aged 6-11 months, RR of 0.90 (0.56-1.42); and in those aged 12-59 months, RR 1.36 (1.06-1.74). The greatest decrease in risk was in hospitalized children under 6 months, RR 0.13 (0.07-0.22).</p><p><strong>Conclusion: </strong>The results support the positive impact that this campaign had, especially on hospitalizations.</p>","PeriodicalId":72916,"journal":{"name":"Enfermedades infecciosas y microbiologia clinica (English ed.)","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-02-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143371449","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The ghost fly attacks unseen.","authors":"Yolanda García Gambín, María Asunción Iborra-Bendicho, Laura Moreno Parrado, Manuel Segovia-Hernández","doi":"10.1016/j.eimce.2025.01.005","DOIUrl":"https://doi.org/10.1016/j.eimce.2025.01.005","url":null,"abstract":"","PeriodicalId":72916,"journal":{"name":"Enfermedades infecciosas y microbiologia clinica (English ed.)","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-02-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143371180","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Infection by Saksenaea vasiformis in Spain: Case report and literature review.","authors":"Iker Villanueva, Laura Guío, Lara Mourelle, Patricia Martín-Playa, Eduardo Vicario, Laura Zaldumbide, Leyre López-Soria, Josune Goikoetxea","doi":"10.1016/j.eimce.2025.01.004","DOIUrl":"https://doi.org/10.1016/j.eimce.2025.01.004","url":null,"abstract":"<p><strong>Introduction: </strong>Saksenaea vasiformis is a filamentous fungus from the Mucorales family, responsible for isolated infections with high morbidity and mortality, especially in tropical or subtropical areas. The objective is to describe the clinical characteristics of the cases reported in Spain.</p><p><strong>Methods: </strong>In addition to presenting a case of S. vasiformis infection treated at Hospital Universitario Cruces in 2023, a systematic literature review was conducted on 17/04/2024, analyzing a total of 11 cases. Epidemiological and clinical data were obtained, and a descriptive analysis was performed.</p><p><strong>Results: </strong>The average age was 64.9 years, with most being male (72.7%) and immunocompetent. Acquisition was related to severe trauma (45.5%) or insect bites (36.4%). 90.1% suffered from skin and soft tissue infections. The diagnostic process was complex, with the following being useful: direct staining (36.4%), culture in specific media (27.3%), molecular techniques (54.5%), and histopathological findings (90.9%). MICs of antifungals was determined in 3 cases, with low MICs for liposomal amphotericin B (L-AMB) and posaconazole, and variable MICs for voriconazole. L-AMB was the most commonly used antifungal, combined in all cases with extensive surgical debridement. Mortality was 45.5%.</p><p><strong>Conclusion: </strong>Infection by S. vasiformis is rare in our environment but clinically significant due to its severity and difficult diagnosis. Rapid recognition, along with early and aggressive debridement and appropriate antifungal treatment, are essential.</p>","PeriodicalId":72916,"journal":{"name":"Enfermedades infecciosas y microbiologia clinica (English ed.)","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-02-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143371450","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Unexpected cause of heart failure in male with prosthetic mitral and aortic valves","authors":"Yolanda García Collado,&nbsp;Lourdes Balderas Fernández,&nbsp;Laura Mora Navas,&nbsp;María Victoria García López","doi":"10.1016/j.eimce.2024.10.001","DOIUrl":"10.1016/j.eimce.2024.10.001","url":null,"abstract":"","PeriodicalId":72916,"journal":{"name":"Enfermedades infecciosas y microbiologia clinica (English ed.)","volume":"43 2","pages":"Pages 113-114"},"PeriodicalIF":0.0,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142514089","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"New ST6423 sequence type of hypervirulent Klebsiella pneumoniae carrying carbapenemase OXA-48-like causing bacteraemia in an immunocompromised patient","authors":"Carmen Palacios Clar,&nbsp;Diego García Martínez de Artola,&nbsp;Julia Alcoba Flórez","doi":"10.1016/j.eimce.2024.12.004","DOIUrl":"10.1016/j.eimce.2024.12.004","url":null,"abstract":"","PeriodicalId":72916,"journal":{"name":"Enfermedades infecciosas y microbiologia clinica (English ed.)","volume":"43 2","pages":"Pages 116-117"},"PeriodicalIF":0.0,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142866743","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Complete genome characterization of mcr-1-mediated colistin-resistant Escherichia coli from outpatients in Bulgaria","authors":"Stefana Sabtcheva ,&nbsp;Ivan Stoikov ,&nbsp;Deyan Donchev ,&nbsp;Sylvia Georgieva ,&nbsp;Elina Dobreva ,&nbsp;Ivan Nikolaev Ivanov","doi":"10.1016/j.eimce.2024.10.006","DOIUrl":"10.1016/j.eimce.2024.10.006","url":null,"abstract":"<div><h3>Introduction</h3><div>This study reports the emergence of <em>mcr-1</em>-mediated colistin resistance in human <em>Escherichia coli</em> isolates from Bulgaria.</div></div><div><h3>Methods</h3><div>Three colistin-resistant <em>E. coli</em> isolates were obtained from outpatient urine specimens. They were subjected to PCR for detection of <em>mcr</em> genes and conjugation experiments. Whole-genome sequencing was employed to analyze the genomic characteristics of the isolates.</div></div><div><h3>Results</h3><div>PCR identified <em>mcr-1</em> in all isolates. In <em>E. coli</em> of sequence type (ST) 2067, <em>mcr-1.1</em> was found on a self-transmissible IncI2 plasmid, while <em>mcr-1.32</em> was chromosomal in the remaining two ST131 <em>E. coli</em> isolates. <em>E. coli</em> ST2067 co-harbored quinolones resistance mutations (<em>gyrA</em>^D87N, <em>gyrA</em>^S83L, <em>parC</em>^S80I), β-lactam (<em>bla</em>_TEM-30) and aminoglycoside (<em>aadA1</em>, <em>aac(3)-IId</em>) resistance genes.</div></div><div><h3>Conclusion</h3><div>This report further confirms the role of IncI2 conjugative plasmids in the dissemination of <em>mcr</em> genes. Our findings involving chromosomal <em>mcr-1</em> in high-risk ST131 <em>E. coli</em> strains from outpatients underscores the need for enhanced surveillance and systematic screening to combat colistin resistance.</div></div>","PeriodicalId":72916,"journal":{"name":"Enfermedades infecciosas y microbiologia clinica (English ed.)","volume":"43 2","pages":"Pages 97-101"},"PeriodicalIF":0.0,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143165032","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}