Alejandro Cumplido , Jesús Aramburu , María Font , Marina Montes , Raquel Abad , Eric López , Albert Bernet , Saray Mormeneo , Iván Prats , Mercè García , Elena Sánchez , Alba Bellés
{"title":"Antimicrobial resistance and epidemiological aspects of Neisseria gonorrhoeae in the province of Lleida, Spain (2017–2024)","authors":"Alejandro Cumplido , Jesús Aramburu , María Font , Marina Montes , Raquel Abad , Eric López , Albert Bernet , Saray Mormeneo , Iván Prats , Mercè García , Elena Sánchez , Alba Bellés","doi":"10.1016/j.eimce.2024.06.012","DOIUrl":"10.1016/j.eimce.2024.06.012","url":null,"abstract":"<div><h3>Introduction</h3><div><em>Neisseria gonorrhoeae</em> (NG) is one of the main causes of sexually transmitted infections and it is reaching high resistance levels worldwide. The aim of this study was to describe the antibiotic resistance, incidence and circulating sequence types of NG in the province of Lleida (Spain).</div></div><div><h3>Methods</h3><div>A total of 487 NG isolates were included in the study (2017–2024). Antibiotic susceptibility testing was performed by gradient diffusion following EUCAST criteria. NG-MAST was performed to 211 isolates in Centro Nacional de Microbiología (Majadahonda, Spain). The study of co-infections was done by real-time PCR (Allplex™ STI, Seegene®).</div></div><div><h3>Results</h3><div>All NG isolates remained susceptible to third-generation cephalosporins. The percentages of resistance to tetracycline, ciprofloxacin and penicillin G were 89.1%, 69.2% and 22.6% respectively. A 7.8% of isolates presented a MIC >1<!--> <!-->mg/L for azithromycin. A decrease in the incidence of gonococcal infections was detected during 2020, followed by a pronounced increase in next years. Ninety-seven different sequence types were detected. ST14994 (14.7%) and ST19792 (6.6%), were the most frequent ST detected in our study. NG appeared as a single STI agent in most cases (77.7%) and <em>Chlamydia trachomatis</em> was the most frequently detected STI agent (74.8%) in samples with co-infections.</div></div><div><h3>Conclusions</h3><div>NG incidence is increasing in our area. The lack of resistance to third-generation cephalosporins and the low level of azithromycin resistance suggest that the use of these antibiotics is a suitable option. Continuous surveillance is essential to prevent the emergence and spread of resistant NG isolates.</div></div>","PeriodicalId":72916,"journal":{"name":"Enfermedades infecciosas y microbiologia clinica (English ed.)","volume":"43 3","pages":"Pages 156-161"},"PeriodicalIF":0.0,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143526839","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Carles Rubio Maturana , Marta Guerrero , Maria Casas Claramunt , Susana Nuria Ayala-Cortés , Victoria López , Patricia Martínez-Vallejo , Begoña Treviño , Elena Sulleiro , Juliana Esperalba , Ariadna Rando , Diana Pou , Maria Luisa Aznar , Pau Bosch-Nicolau , Fernando Salvador , Inés Oliveira-Souto , Israel Molina , Núria Serre-Delcor
{"title":"Seroprevalence status of vaccine-preventable diseases in migrants living in shelter centers in Barcelona, Spain","authors":"Carles Rubio Maturana , Marta Guerrero , Maria Casas Claramunt , Susana Nuria Ayala-Cortés , Victoria López , Patricia Martínez-Vallejo , Begoña Treviño , Elena Sulleiro , Juliana Esperalba , Ariadna Rando , Diana Pou , Maria Luisa Aznar , Pau Bosch-Nicolau , Fernando Salvador , Inés Oliveira-Souto , Israel Molina , Núria Serre-Delcor","doi":"10.1016/j.eimce.2024.04.010","DOIUrl":"10.1016/j.eimce.2024.04.010","url":null,"abstract":"<div><h3>Introduction</h3><div>Almost 281 million people were living in a foreign country in 2022, and more than 100 million were displaced because of war conflicts and human right violations. Vaccination coverage of infectious diseases in migrants from some disadvantaged settings could be lower than reception countries populations, consequently seroprevalence studies and better access to vaccination could contribute to reducing these differences.</div></div><div><h3>Methods</h3><div>A descriptive retrospective cross-sectional study was conducted including migrants, living ≤5 years in the reception country and ≥16 years old, who requested a medical exam between January 1st, 2020 and January 31st, 2021. Seroprevalence assessment was performed, and vaccination was offered to those individuals without immunity to hepatitis B, hepatitis A, varicella, measles, mumps, and rubella.</div></div><div><h3>Results</h3><div>A total of 315 migrants were attended during the study period. Immunity protection at arrival was 252/296 (85.1%) for measles, 274/295 (92.9%) for rubella, 257/296 (86.8%) for mumps, 264/295 (89.5%) for varicella, 267/313 (85.3%) for hepatitis A, and 104/300 (34.6%) for hepatitis B. The final immunity protection after full vaccination schedules was 278/296 (93.9%) for measles, 287/295 (97.3%) for rubella, 274/296 (92.6%) for mumps, 276/295 (93.6%) for varicella, 280/313 (89.5%) for hepatitis A, and 139/300 (46.3%) for hepatitis B.</div></div><div><h3>Conclusions</h3><div>The vaccination intervention has increased immunity rates for the studied diseases in the attended migrants in our center, however, such interventions should be maintained to reach local population immunization levels. Moreover, the collaboration between shelter and reference specialized health centers is fundamental to implement such vaccination programs.</div></div>","PeriodicalId":72916,"journal":{"name":"Enfermedades infecciosas y microbiologia clinica (English ed.)","volume":"43 3","pages":"Pages 139-147"},"PeriodicalIF":0.0,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141433560","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Ana Cotos Suárez, Fernando García-Garrote, Laura Sancha Domínguez, Ana María Blázquez de Castro, María del Mar Collado Llano, Eva María Lorenzo Iglesias
{"title":"Prevalence and antimicrobial susceptibility profile of Corynebacterium glucuronolyticum in genitourinary tract samples","authors":"Ana Cotos Suárez, Fernando García-Garrote, Laura Sancha Domínguez, Ana María Blázquez de Castro, María del Mar Collado Llano, Eva María Lorenzo Iglesias","doi":"10.1016/j.eimce.2024.10.008","DOIUrl":"10.1016/j.eimce.2024.10.008","url":null,"abstract":"<div><h3>Introduction</h3><div><em>Corynebacterium glucuronolyticum</em> (<em>C. glucuronolyticum</em>) is a species recently recognized as a potential pathogen of the male genitourinary tract. The objective is to determine the prevalence of <em>C. glucuronolyticum</em> in genitourinary tract samples as well as their antimicrobial susceptibility profile.</div></div><div><h3>Methods</h3><div>A prospective study was conducted from 1st of November 2021 to the 30th of November 2022, for all genitourinary tract samples collected from male patients with suspicion of balanitis, prostatitis and urethritis. Antimicrobial susceptibility testing was performed in all <em>C. glucuronolyticum</em> isolates.</div></div><div><h3>Results</h3><div>A total of 73 <em>C. glucuronolyticum</em> isolates from 693 clinical specimens were obtained. This represents an overall <em>C. glucuronolyticum</em> prevalence of 10.5%. All strains were susceptible to vancomycin, linezolid and rifampicin, whereas 94%, 68% and 65% were resistant to clindamycin, tetracycline and ciprofloxacin, respectively.</div></div><div><h3>Conclusion</h3><div>Clinical microbiology laboratories should perform antimicrobial susceptibility testing against <em>C. glucuronolyticum</em> due to the significant rate of resistance to ciprofloxacin and tetracycline.</div></div>","PeriodicalId":72916,"journal":{"name":"Enfermedades infecciosas y microbiologia clinica (English ed.)","volume":"43 3","pages":"Pages 162-164"},"PeriodicalIF":0.0,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143526840","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Sofía De la Villa , Verónica Parras , Leire Pérez-Latorre , Pablo Martín-Rabadán
{"title":"An exceptional cause of brain abscess","authors":"Sofía De la Villa , Verónica Parras , Leire Pérez-Latorre , Pablo Martín-Rabadán","doi":"10.1016/j.eimce.2024.09.012","DOIUrl":"10.1016/j.eimce.2024.09.012","url":null,"abstract":"","PeriodicalId":72916,"journal":{"name":"Enfermedades infecciosas y microbiologia clinica (English ed.)","volume":"43 3","pages":"Pages 177-178"},"PeriodicalIF":0.0,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143526965","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Luis Gago , Elvira Baos , Mercedes Martínez-Rodríguez , Alberto Delgado-Iribarren
{"title":"Parvovirus B19 and central nervous system: A case series","authors":"Luis Gago , Elvira Baos , Mercedes Martínez-Rodríguez , Alberto Delgado-Iribarren","doi":"10.1016/j.eimce.2024.10.007","DOIUrl":"10.1016/j.eimce.2024.10.007","url":null,"abstract":"","PeriodicalId":72916,"journal":{"name":"Enfermedades infecciosas y microbiologia clinica (English ed.)","volume":"43 3","pages":"Pages 183-184"},"PeriodicalIF":0.0,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143526967","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
M. Eulalia Valencia , Tatiana Pirogova , Delia Romera , Marta Montero , María Tasías , José Sanz , Alberto Arranz , Jorge Vergas , M. Jesús Tellez , Francisco Fanjul , Antoni Campins , Miguel Cervero , Inmaculada Jarrín , Marta de Miguel , Luz Martín Carbonero , María Yllescas , Juan González
{"title":"Prospective study for the early detection of lung carcinoma in patients with HIV infection (GESIDA study 8815)","authors":"M. Eulalia Valencia , Tatiana Pirogova , Delia Romera , Marta Montero , María Tasías , José Sanz , Alberto Arranz , Jorge Vergas , M. Jesús Tellez , Francisco Fanjul , Antoni Campins , Miguel Cervero , Inmaculada Jarrín , Marta de Miguel , Luz Martín Carbonero , María Yllescas , Juan González","doi":"10.1016/j.eimce.2024.05.005","DOIUrl":"10.1016/j.eimce.2024.05.005","url":null,"abstract":"<div><h3>Introduction</h3><div>Lung cancer (LC) screening detects tumors early. The prospective GESIDA 8815 study was designed to assess the usefulness of this strategy in HIV + people (PLHIV) by performing a low-radiation computed tomography (CT) scan.</div></div><div><h3>Patients and methods</h3><div>371 heavy smokers patients were included (>20 packs/year), >45 years old and with a CD4+ <200 mm<sup>3</sup> nadir. One visit and CT scan were performed at baseline and 4 for follow-up time annually.</div></div><div><h3>Results</h3><div><span><span><span>329 patients underwent the baseline visit and CT (CT0) and 206 completed the study (CT1 = 285; CT2 = 259; CT3 = 232; CT4 = 206). All were receiving ART. A total >8 mm </span>lung nodules were detected, and 9 early-stage PCs were diagnosed (4 on CT1, 2 on CT2, 1 on CT3 and 2 on CT4). There were no differences between those who developed LC and those who did not in sex, age, CD4+ nadir, previous </span>lung disease<span>, family history, or amount of packets/year. At each visit, other pathologies were diagnosed, mainly COPD, calcified </span></span>coronary artery<span> and residual tuberculosis lesions. At the end of the study, 38 patients quit smoking and 75 reduced their consumption. Two patients died from LC and 16 from other causes (p = 0.025).</span></div></div><div><h3>Conclusions</h3><div>The design of the present study did not allow us to define the real usefulness of the strategy. Adherence to the test progressively decreased over time. The diagnosis of other thoracic pathologies is very frequent. Including smokers in an early diagnosis protocol for LC could help to quit smoking.</div></div>","PeriodicalId":72916,"journal":{"name":"Enfermedades infecciosas y microbiologia clinica (English ed.)","volume":"43 3","pages":"Pages 125-132"},"PeriodicalIF":0.0,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140913582","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Abelardo Claudio Fernández Chávez, Guillermo Yovany Ordoñez León, Eva Elisa Álvarez León, Paloma Moreno Núñez, José Porto Tomás, Jesús María Aranaz Andrés
{"title":"Similar risk of hospitalization and lethality from COVID-19 in transplant recipients and waitlisted patients: A comparative analysis.","authors":"Abelardo Claudio Fernández Chávez, Guillermo Yovany Ordoñez León, Eva Elisa Álvarez León, Paloma Moreno Núñez, José Porto Tomás, Jesús María Aranaz Andrés","doi":"10.1016/j.eimce.2025.02.005","DOIUrl":"https://doi.org/10.1016/j.eimce.2025.02.005","url":null,"abstract":"<p><strong>Introduction: </strong>In 2022, Spanish health authorities recommended passive immunisation against COVID-19 for solid organ transplant recipients (SOT), due to their deficient post-vaccination humoral response. Patients on the transplant waiting list (SOTwl) were excluded from this strategy.</p><p><strong>Objective: </strong>To compare the risk of hospitalisation, ICU admission, and mortality due to COVID-19 between SOT and SOTwl patients.</p><p><strong>Methodology: </strong>Patients seen in the Preventive Medicine Department at Ramón y Cajal Hospital between 03/14/2020 and 04/13/2022. The relative risk (RR) of hospitalisation, ICU admission, and mortality was estimated among SOT and SOTwl patients, adjusted for age, sex, and vaccine doses.</p><p><strong>Results: </strong>A total of 1292 patients were analyzed. SOT patients (n=1153) were older and had similar risks of hospitalisation (RR 0.97, 95% CI 0.57-1.64), ICU admission (RR 1.74, 95 % CI 0.44-6.86), and death (RR 0.89, 95% CI 0.45-1.77) compared to SOTwl patients (n=139).</p><p><strong>Conclusions: </strong>The risks of hospitalisation, ICU admission, and mortality were similar between SOT and SOTwl patients.</p>","PeriodicalId":72916,"journal":{"name":"Enfermedades infecciosas y microbiologia clinica (English ed.)","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-02-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143538116","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
M Angeles Gutiérrez Rodríguez, Cristina Rodríguez Luque, Amaya Sánchez Gómez, M Dolores Lasheras Carbajo, Soledad Cañellas Llabrés, Beatriz Lopez Centeno, Diego Morales Irala, María C Vázquez Torres, Marta Molina Olivas
{"title":"Factors associated with vaccination against mpox in people under preexposure prophylaxis against HIV in the Community of Madrid.","authors":"M Angeles Gutiérrez Rodríguez, Cristina Rodríguez Luque, Amaya Sánchez Gómez, M Dolores Lasheras Carbajo, Soledad Cañellas Llabrés, Beatriz Lopez Centeno, Diego Morales Irala, María C Vázquez Torres, Marta Molina Olivas","doi":"10.1016/j.eimce.2025.02.003","DOIUrl":"https://doi.org/10.1016/j.eimce.2025.02.003","url":null,"abstract":"<p><strong>Introduction: </strong>In May 2022, a mpox outbreak was identified in Europe. The majority of those affected are young men with risky sexual relations. In Spain, to control the outbreak, vaccination is recommended, among others, for people on HIV pre-exposure prophylaxis (PrEP). The objective of the study is to determine the factors associated with vaccination against mpox in people included in PrEP in the Community of Madrid.</p><p><strong>Methods: </strong>Descriptive study. The sources of information used are: the PrEP Registry, Health Card, the Vaccine Registry and the Primary Care Clinical History. The 2011 deprivation index of the Spanish Society of Epidemiology is used as a socioeconomic indicator. Factors related to vaccination against mpox are analysed and a conditional logistic regression model is fitted.</p><p><strong>Results: </strong>6690 people were registered for PrEP. The average age was 37.7 years, 98.8% were men and 25.1% were foreigners. 39.9% had received vaccination against mpox, 47.6% had vaccination against hepatitis A, 32.8% vaccination against hepatitis B, 53.3% vaccination against COVID-19 and 24.3% vaccination against a complaint. The variables associated with mpox vaccination were age, country of birth, influenza vaccination, hepatitis A vaccination, COVID-19 vaccination, and deprivation index.</p><p><strong>Conclusions: </strong>Men who had sex with men (MSM) on PrEP treatment, young adults, born in Spain, with a history of vaccination against influenza, hepatitis A and COVID-19 have a greater probability of vaccination against mpox. The proportion of vaccinated subjects decreases as the deprivation index increases (as socioeconomic level decreases).</p>","PeriodicalId":72916,"journal":{"name":"Enfermedades infecciosas y microbiologia clinica (English ed.)","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-02-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143538111","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}