ECS sensors plus最新文献_第6页

Towards Modern-Age Advanced Sensors for the Management of Neurodegenerative Disorders: Current Status, Challenges and Prospects 走向现代用于神经退行性疾病治疗的先进传感器：现状、挑战和前景

ECS sensors plus Pub Date : 2022-10-04 DOI: 10.1149/2754-2726/ac973e

Akash Gautam

引用次数: 6

A Paradigm of Internet-of-Nano-Things Inspired Intelligent Plant Pathogen-Diagnostic Biosensors 基于纳米物联网的智能植物病原体诊断生物传感器

ECS sensors plus Pub Date : 2022-09-19 DOI: 10.1149/2754-2726/ac92ed

S. Sonu, Vishal Chaudhary

引用次数: 36

Review—Interleukins Profiling for Biosensing Applications: Possibilities and the Future of Disease Detection 综述——白细胞介素谱在生物传感应用中的应用：疾病检测的可能性和未来

ECS sensors plus Pub Date : 2022-09-15 DOI: 10.1149/2754-2726/ac9227

Shashank Shekhar, Ajay Kumar, A. Khosla, P. Solanki

{"title":"Review—Interleukins Profiling for Biosensing Applications: Possibilities and the Future of Disease Detection","authors":"Shashank Shekhar, Ajay Kumar, A. Khosla, P. Solanki","doi":"10.1149/2754-2726/ac9227","DOIUrl":"https://doi.org/10.1149/2754-2726/ac9227","url":null,"abstract":"Interleukins (ILs) are a major subclass of cytokines acting as molecular messengers playing role in immune system responses via a cascade of signaling pathways. Belonging to the cytokine family, the ILs play a crucial role in the theranostics of various diseases. Their abnormal expression leads to the development of various diseases such as cancer, neurodegenerative diseases, allergies, asthma, autoimmune diseases, and other physiological abnormalities. This paves the path of exploring the ILs for the development of sensitive and efficient biosensors and promoting them for clinical testing in a wide array of diseases. Further, detecting the level of ILs is very important for their early diagnosis and their progression within the body, and simultaneously their possible immunotherapeutic approaches. To achieve this goal, multidisciplinary scientific approaches involving immunology, electrochemistry, nanotechnology, photometry, etc. are already being put into action. The advancements in nanoscience and nanotechnology are aiding the development of highly sensitive biosensors for ILs detection. This review focuses on giving a detailed description of all the presently discovered ILs and their role in various diseases. Simultaneously, it also discusses the various electrochemical biosensors that can be employed for the detection of ILs in body fluids. Moreover, the role of nanomaterials in electrochemical biosensing is also discussed in this review.","PeriodicalId":72870,"journal":{"name":"ECS sensors plus","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-09-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44934531","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 6

Suppression of Impedimetric Baseline Drift for Stable Biosensing 抑制阻抗基线漂移用于稳定生物传感

ECS sensors plus Pub Date : 2022-09-06 DOI: 10.1149/2754-2726/ac8fa1

Hilena F. Gezahagne, E. L. Brightbill, Decarle S. Jin, Siamalan Krishnathas, B. Brown, M. Mooney, A. O’Riordan, Niamh Creedon, Caoimhe Robinson, E. Vogel

{"title":"Suppression of Impedimetric Baseline Drift for Stable Biosensing","authors":"Hilena F. Gezahagne, E. L. Brightbill, Decarle S. Jin, Siamalan Krishnathas, B. Brown, M. Mooney, A. O’Riordan, Niamh Creedon, Caoimhe Robinson, E. Vogel","doi":"10.1149/2754-2726/ac8fa1","DOIUrl":"https://doi.org/10.1149/2754-2726/ac8fa1","url":null,"abstract":"Biosensors based on Electrochemical Impedance Spectroscopy (EIS) detect the binding of an analyte to a receptor functionalized electrode by measuring the subsequent change in the extracted charge-transfer resistance (RCT). In this work, the stability of a long chain alkanethiol, 16-mercaptohexadecanoic acid was compared to that of a polymer-based surface linker, ortho-aminobenzoic acid (o-ABA). These two classes of surface linkers were selected due to the marked differences in their structural properties. The drift in RCT observed for the native SAM functionalized gold electrodes was observed to correlate to the drift in the subsequent receptor functionalized SAM. This indicates the importance of the gold-molecule interface for reliable biosensing. Additionally, the magnitude of the baseline drift correlated to the percentage of thiol molecules improperly bound to the gold electrode as evaluated using X-ray Photoelectron Spectroscopy (XPS). Alternatively, the o-ABA functionalized gold electrodes demonstrated negligible drift in the RCT. Furthermore, these polymer functionalized gold electrodes do not require a stabilization period in the buffer solution prior to receptor functionalization. This work emphasizes the importance of understanding and leveraging the structural properties of various classes of surface linkers to ensure the stability of impedimetric measurements.","PeriodicalId":72870,"journal":{"name":"ECS sensors plus","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-09-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"45300252","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

Flow Injection Analysis-Based Electrochemiluminescence: An Overview of Experimental Design and Its Biosensing Applications 基于流动注射分析的电化学发光:实验设计及其生物传感应用综述

ECS sensors plus Pub Date : 2022-08-29 DOI: 10.1149/2754-2726/ac8d70

C. Venkateswara Raju, Gokana Mohana Rani, J. Haribabu, Shanmugam Senthil Kumar

{"title":"Flow Injection Analysis-Based Electrochemiluminescence: An Overview of Experimental Design and Its Biosensing Applications","authors":"C. Venkateswara Raju, Gokana Mohana Rani, J. Haribabu, Shanmugam Senthil Kumar","doi":"10.1149/2754-2726/ac8d70","DOIUrl":"https://doi.org/10.1149/2754-2726/ac8d70","url":null,"abstract":"Over the past few decades, electrochemiluminescence (ECL) has been used as a powerful analytical tool for in vitro diagnosis due to its promising potential in light-emitting and, which has greatly promoted recent for biosensor studies. Plenty of research articles on the ECL technique have been published by various researchers around the globe. On the other hand, studies on the coupling of ECL sensing strategies with other techniques are recently getting widespread attention. ECL strategies have been effectively coupled with scanning electrochemical microscope (SECM), flow injection analysis (FIA), and capillary electrophoresis. These coupled techniques have been effectively employed for various health care applications. Among these techniques, FIA coupled ECL sensing strategies have been designated as the most emerging technique, especially sensing of clinical samples. This critical review discusses the vibrant developments in FIA-ECL, the mechanism of ECL, the design of FIA-ECL, and highlights the application of FIA-ECL for the detection of immunoassays, catecholamines, antioxidant compounds, choline, tetracyclines, and pharmaceutical drugs. The current review will pave the way for the design and development of FIA-ECL for efficient point-of-care applications.","PeriodicalId":72870,"journal":{"name":"ECS sensors plus","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-08-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44505140","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 3

Detection of Methylparaben in Cosmetics by Poly L–Lysine/Reduced Graphene Oxide-Based Sensor 聚l -赖氨酸/还原氧化石墨烯传感器检测化妆品中对羟基苯甲酸甲酯

ECS sensors plus Pub Date : 2022-08-18 DOI: 10.1149/2754-2726/ac8aa7

D. Nguyen, Tran Thanh Tam Toan

引用次数: 8

Multimodal Single-Entity Electrochemical Fluoride Sensor for Fuel Cell Membrane Degradation Diagnostics 用于燃料电池膜降解诊断的多模态单实体电化学氟化物传感器

ECS sensors plus Pub Date : 2022-08-18 DOI: 10.1149/2754-2726/ac8aa8

R. López, Justin Fuentes, Adrian Gonzalez-Camps, T. Benhaddouch, A. Kaushik, Christopher Lloyd Metler, S. Bhansali, D. Dong

{"title":"Multimodal Single-Entity Electrochemical Fluoride Sensor for Fuel Cell Membrane Degradation Diagnostics","authors":"R. López, Justin Fuentes, Adrian Gonzalez-Camps, T. Benhaddouch, A. Kaushik, Christopher Lloyd Metler, S. Bhansali, D. Dong","doi":"10.1149/2754-2726/ac8aa8","DOIUrl":"https://doi.org/10.1149/2754-2726/ac8aa8","url":null,"abstract":"To the best of our knowledge, very few works have been done for the continuous real-time monitoring of Proton Exchange Membrane Fuel Cells (PEMFCs) membrane degradation based on fluoride-specific electrochemical microsensors. PEMFCs are eco-smart energy sources for efficient transportation but experience variable degradation rates that wear the Membrane Electrode Assembly (MEA), a critical component of the fuel cell’s functionality. Current market options lack specific diagnostics and a legitimate indication of when exactly the membrane needs to be replaced. As such, this work focused on manufacturing a sensor for measuring MEA degradation in real-time by selectively monitoring fluoride concentration in effluent water, a signature PEMFCs degradation status, through functionalized LaF3:(Au nanoparticle) thin films (∼60 nm). The sensor’s exceptional specificity/sensitivity has been achieved in real-time at a sub 10 ppb level, optimized through spin-coating deposition and post-annealing process. Its multimodal readout has been achieved and studied through the characterizations of open circuit potential, cyclic voltammetry, chronoamperometry, and differential pulse voltammetry revealing a consistent linear decrease of 15.7 mA cm−2 at 0 ppb to 10.2 mA cm−2, while also maintaining its low-cost, small size, and robustness.","PeriodicalId":72870,"journal":{"name":"ECS sensors plus","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-08-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43714808","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

Proof Before Submission 提交前证明

ECS sensors plus Pub Date : 2022-08-16 DOI: 10.1149/2754-2726/ac865b

P. Cooper

引用次数: 0

Review—Electrochemical Sensors Used for the Determination of Some Antifungal Azoles 电化学传感器测定某些抗真菌唑类药物的研究进展

ECS sensors plus Pub Date : 2022-08-11 DOI: 10.1149/2754-2726/ac88e3

Bianca-Maria Ţuchiu, Raluca-Ioana Ștefan-van Staden, J. V. van Staden

引用次数: 2

Numerical Investigation on Photon Sensing Parameters for Some Thermoluminescence Dosimeters: A Comparative Study 几种热致发光剂量计光子传感参数的数值研究——比较研究

ECS sensors plus Pub Date : 2022-08-01 DOI: 10.1149/2754-2726/ac85ca

Harjot Kaur, Pardeep Kaur, Preet Kaur, T. Singh

{"title":"Numerical Investigation on Photon Sensing Parameters for Some Thermoluminescence Dosimeters: A Comparative Study","authors":"Harjot Kaur, Pardeep Kaur, Preet Kaur, T. Singh","doi":"10.1149/2754-2726/ac85ca","DOIUrl":"https://doi.org/10.1149/2754-2726/ac85ca","url":null,"abstract":"In the present work, twelve inorganic thermoluminescence dosimeteric (TLD) materials doped with some rare earth elements (LiF:Sm, LiBaP2O7:Eu, CaCO3:Eu, CaSO4:Dy, SrSO4:Sm, CdSO4:Dy, BaSO4:Eu, Li2B4O7:Dy, MgB4O7:Gd, Al2O3:Gd, MgAl2O4:Ce and LiCaAlF6:Eu) and three organic TLD materials (C3H7NO2, C7H8O2 and C4H6BaO4) were selected for comparative analysis on the basis of different photon sensing parameters. About nine photon sensing parameters viz. mass attenuation coefficient (MAC), linear attenuation coefficient (LAC), mean free path (mfp), half value layer (HVL), tenth value layer (TVL), effective atomic number (EAN), effective electron number (EEN), exposure buildup factor (EBF) and energy absorption buildup factor (EABF) were obtained for the selected fifteen TLDs. The simultaneous variation of these photon sensing parameters for the selected TLDs with photon energy and composition has been analyzed. The results of present comparative analysis help radiation physicists to easily select a particular dosimeter for their research laboratory from different existing compositions. All photon sensing parameters viz. MAC, LAC, mfp, HVL, TVL, EAN, EEN, EBF and EABF for selected TLDs strongly depend upon incident energy and chemical composition in lower and higher energy regions. Among the selected TLDs; BaSO4: Eu3+ offers best results (maximum values for MAC, EAN, EEN; and minimum values for mfp, HVL, TVL, EBF, EABF); whereas MgB4O7:Gd3+ offers EAN value close to tissue and less variation in most of the sensing parameters with respect to photon energy.","PeriodicalId":72870,"journal":{"name":"ECS sensors plus","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42053648","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1