Discover mental health最新文献

{"title":"Polygenic scores and symptom severity change after internet-delivered cognitive behaviour therapy for depression and anxiety.","authors":"Julia Bäckman, John Wallert, Matthew Halvorsen, James J Crowley, David Mataix-Cols, Christian Rück","doi":"10.1007/s44192-025-00213-6","DOIUrl":"10.1007/s44192-025-00213-6","url":null,"abstract":"<p><p>Depressive and anxiety disorders are leading causes of disability globally. Therapist-guided, Internet-delivered cognitive behaviour therapy (ICBT) is an established treatment for depression and anxiety, but a considerable proportion of treated patients do not achieve sufficient improvement. Predicting symptom changes based solely on clinical variables is challenging, and genetic data could offer additional insights into who might benefit most from ICBT. We conducted a study of 2,668 adults (62% women, average age 35.6) from the Swedish MULTI-PSYCH cohort, to investigate the association between polygenic scores (PGS) for eight psychiatric and cognitive traits and symptom change after ICBT. All participants had been diagnosed with depression, panic disorder or social anxiety disorder. The primary outcome was a harmonised symptom score. Using large discovery data sets, PGSs were computed for ADHD, autism spectrum disorder, bipolar disorder, major depressive disorder and schizophrenia, cross-disorder psychopathology, educational attainment, and intelligence. Linear mixed-effects models identified a significant negative association between PGS for educational attainment (PGS-EDU) and symptom severity in the adjusted model (B = - 0.69, p = 0.034), suggesting that a higher PGS-EDU was associated with lower symptom severity. There was also a significant PGS-EDU*time interaction, indicating that PGS-EDU also influenced the symptom change rate. When excluding outliers, these effects remained statistically significant. No other PGSs were statistically significant. Sensitivity analysis showed that self-reported education level provided a stronger association to the outcome than PGS-EDU, indicating that the potential clinical applications of PGS are currently limited. While these results await replication, they could have important implications for how the ICBT could be adapted to suit a wider portion of the population.</p>","PeriodicalId":72827,"journal":{"name":"Discover mental health","volume":"5 1","pages":"82"},"PeriodicalIF":0.0,"publicationDate":"2025-06-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12130394/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144200934","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The devastating impact of conflict in Sudan on mental health services: a rapid review.","authors":"Wagd Mutaz Osman, Leena Abdelghani Mohamed, Abdulqadir J Nashwan","doi":"10.1007/s44192-025-00207-4","DOIUrl":"10.1007/s44192-025-00207-4","url":null,"abstract":"<p><p>Sudan's healthcare system teeters on the brink of collapse as the country continues to reel from political instability and conflict that escalated in April 2023. The latest outbreak of violence between the national army and the Rapid Support Forces has exacerbated an already fragile healthcare infrastructure. This review provides a narrative synthesis of the existing literature and reports on the current state of mental health services in Sudan. The ongoing conflict has triggered widespread displacement, economic instability, and trauma, which have in turn contributed to increased rates of mental illness. While mental health services were limited even before the conflict, the current crisis has significantly reduced access to care, especially for vulnerable populations. In this review, we highlight the urgent need for comprehensive mental health interventions and sustained support for healthcare providers under increasingly dangerous conditions.</p>","PeriodicalId":72827,"journal":{"name":"Discover mental health","volume":"5 1","pages":"81"},"PeriodicalIF":0.0,"publicationDate":"2025-06-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12130403/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144200980","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"An investigation into the prevalence and perceptions of mental health disorders in Appalachian West Virginia.","authors":"Tyann Dotson, Jerry Derringer, Lauren Hudson Rose, Nathan L Vanderford, Amanda Hinkle, Lindsay E Cormier","doi":"10.1007/s44192-025-00218-1","DOIUrl":"10.1007/s44192-025-00218-1","url":null,"abstract":"<p><strong>Introduction: </strong>Appalachian West Virginia's population is disproportionately afflicted by mental illness, with Logan County having the highest depression rates in the United States. To further understand the mental health situation in Appalachian West Virginia, this research study aims to evaluate the prevalence and perceptions of mental health disorders among patients of Coalfield Health Center.</p><p><strong>Methods: </strong>An online survey was administered to patients at Coalfield Health Center containing 25 questions categorized into three parts: demographic, beliefs/perceptions about behavioral health, and behavioral healthcare access.</p><p><strong>Findings: </strong>The data demonstrated that 37% of participants had received a mental illness diagnosis and 82% knew someone with a mental illness. Nearly 10% of participants denied having reliable transportation or health insurance coverage. Patients reported lacking mental health knowledge and a majority indicated a need for mental health education.</p><p><strong>Conclusions: </strong>The data affirm a high prevalence of mental illness in Logan County, with barriers to care including a negative community perception, low socioeconomic status, lack of access to resources, and low health literacy.</p>","PeriodicalId":72827,"journal":{"name":"Discover mental health","volume":"5 1","pages":"80"},"PeriodicalIF":0.0,"publicationDate":"2025-05-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12125426/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144188621","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The association between physical activity and depressive symptoms in U.S. adults is modulated by sleep duration: gender disparities.","authors":"Juxiang Yang, Xi Zheng, Yi Wang, Hongchu Wang, Gang Song","doi":"10.1007/s44192-025-00212-7","DOIUrl":"10.1007/s44192-025-00212-7","url":null,"abstract":"<p><strong>Background: </strong>The joint effects of physical activity and sleep duration on depression remain unclear. The aim of this study is to explore the independent and joint associations between physical activity (PA) and sleep duration with depressive symptoms.</p><p><strong>Methods: </strong>We included and analyzed 18,052 participants (age ≥ 20 years) from the cross-sectional National Health and Nutrition Examination Survey (NHANES) conducted between 2007 and 2014.</p><p><strong>Results: </strong>After adjustment, both males and females showed a significant correlation between PA, sleep duration, and depressive symptoms. In the joint association analysis, we found: 1. The interaction between PA and sleep duration was statistically significant in males but not significant in females (P = 0.380). 2. Compared to individuals with the lowest PA level and not meeting the National Sleep Foundation's (NSF) guidelines, those with the highest PA level and recommended sleep duration had a 79% decrease in depression risk in males (odds ratio [OR] 0.21, 95% confidence interval [CI] 0.14-0.32) and a 74% decrease in females (OR 0.26, 95% CI 0.20-0.35). 3. In male participants adhering to NSF guidelines, each increase in PA quartile is associated with a 19% reduction in the risk of depression (OR 0.81, 95% CI 0.71-0.92). Conversely, among male participants not adhering to NSF guidelines, there is a 23% decrease in depression risk (OR 0.77, 95% CI 0.69-0.86). For female participants, the respective reductions in depression risk are 20% (OR 0.80, 95% CI 0.73-0.89) and 14% (OR 0.86, 95% CI 0.80-0.93).</p><p><strong>Conclusion: </strong>For males, adherence to recommended sleep duration weakens the relationship between physical activity and depression, while the opposite is observed for females.</p>","PeriodicalId":72827,"journal":{"name":"Discover mental health","volume":"5 1","pages":"79"},"PeriodicalIF":0.0,"publicationDate":"2025-05-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12125408/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144188622","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A summary review of the development of using a brief imagery-competing task intervention (ICTI) for reducing intrusive memories of psychological trauma: applications in healthcare settings for both staff and patients.","authors":"Julie Highfield, Lalitha Iyadurai, Emily A Holmes","doi":"10.1007/s44192-025-00205-6","DOIUrl":"10.1007/s44192-025-00205-6","url":null,"abstract":"<p><p>Psychological trauma for those utilising and delivering healthcare is common, and in particular the experience of repeated and unwanted intrusive memories (IM) of the trauma can occur. There are several psychological interventions that have been shown to be effective with the full syndrome of Post Traumatic Stress Disorder (PTSD), but researchers have only recently explored targeted interventions for IMs. This review provides a summary of a body of work on a behavioural technique called \"Imagery Competing Task Intervention\" (ICTI) for intrusive memories after trauma by Holmes and colleagues. The papers presented outline the underlying cognitive science, the historical development of the intervention, and its application to various different populations in healthcare settings including clinical tests of efficacy. Settings and populations include traumatic events experienced by emergency department patients and emergency caesarean section patients, as well as after work-related trauma experienced by intensive care staff and wider healthcare staff. Timing of ICTI intervention delivery has included the same day of trauma, within 72 h and for older memories weeks, months (or years) post-trauma. The intervention has been delivered with a guided session, which in some studies is in person and some remotely via digital health application. There is a brief overview of other related interventions. The ICTI approach shows potential scalability in trauma laden environments such as healthcare, where exposure is unlikely to be limited or managed and symptoms such as subclinical IMs are common. As such the intervention could be used in a preventing-and-treating approach and in subclinical-to-clinical samples who have IMs after exposure to psychological trauma. Future research would be needed to test ICTI as an intervention for the full syndrome of PTSD.</p>","PeriodicalId":72827,"journal":{"name":"Discover mental health","volume":"5 1","pages":"78"},"PeriodicalIF":0.0,"publicationDate":"2025-05-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12116969/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144164152","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Understanding root causes of homelessness in Marin County, CA and prevention strategies through semi-structured interviews and constant comparative analysis.","authors":"Michaela F George, Kelsey M Bas, Joseph A Blakely, Naila I Saghir, Garrett T Siebels, Liliana Valle-Contreras, Sehrish Khan","doi":"10.1007/s44192-025-00208-3","DOIUrl":"10.1007/s44192-025-00208-3","url":null,"abstract":"<p><strong>Introduction: </strong>Even with the increased prevalence of homelessness in the US, there is limited research that investigates circumstances that can lead to homelessness, especially in affluent communities in California. This lack of understanding, even when resources are available, perpetuates the inequities in health and wellbeing statewide, connection to basic necessities, effective prevention strategies, and meaningful policy changes.</p><p><strong>Methods: </strong>This qualitative analysis consisted of a total of 24, semi-structured interviews conducted in the Spring of 2023 by public health researchers. Participants (18 and older) who were seeking support from a local community partner (the Ritter Center) were interviewed. Interviews consisted of a verbal consent in English and a set of IRB approved questions about the participants life circumstances and background that may have led to homelessness. Transcribed interviews were coded, and several themes emerged.</p><p><strong>Results: </strong>Thematic analysis supports three main themes: lack of resources, mental health struggles and past trauma, and safety and health issues. Lack of resources draws attention for more access to sustainable housing opportunities to prevent homeless in the first place. Struggles with mental health stemmed from extreme childhood trauma including stories of abandonment. Substance use and misuse were reported both before and after experiencing homelessness. Many participants expressed current concerns about their relationship with safety and overall health for many years.</p><p><strong>Conclusions: </strong>Common themes suggest that there are recurrent circumstances that lead to individuals experiencing homelessness. Understanding the root causes of homelessness can help public health departments, local government and organizations implement upstream interventions to prevent the perpetuation of homelessness.</p>","PeriodicalId":72827,"journal":{"name":"Discover mental health","volume":"5 1","pages":"77"},"PeriodicalIF":0.0,"publicationDate":"2025-05-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12106166/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144144729","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Trauma type affects the perceived severity of symptoms and intensity of the recommended intervention in laypeople's perspective on PTSD.","authors":"Mariam Katsarava, Julia Schilcher-Freier, Robert Gaschler","doi":"10.1007/s44192-025-00199-1","DOIUrl":"10.1007/s44192-025-00199-1","url":null,"abstract":"<p><p>Post-Traumatic Stress Disorder (PTSD) is a prevalent mental health condition that can significantly impair individual's daily life. PTSD literacy can help not only those affected cope with the condition but also facilitate laypeople's interactions with those who have experienced or currently suffer from PTSD. However, it is not well-established whether and how the perceived severity of the traumatic event and the supposed need for intervention depend on the causes of PTSD. In the present experiment, we systematically varied the cause across vignettes while holding other aspects constant. Analyses revealed significant differences in severity ratings of the traumatic experience across conditions. The sexual assault and military combat conditions stood out with the highest ratings. Furthermore, severity ratings predicted the intensity of the intervention participants recommended, and both ratings were higher for female participants compared to male participants. While the study confirms the impact of the cause of PTSD on the severity assumed by laypeople, our results diverge from earlier findings in that sexual assault led to particularly high ratings in the current study.</p>","PeriodicalId":72827,"journal":{"name":"Discover mental health","volume":"5 1","pages":"75"},"PeriodicalIF":0.0,"publicationDate":"2025-05-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12098217/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144121520","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Rethinking on the interplay of substance abuse and mental health in Indian prisons: a critical analysis.","authors":"Sruti Bansal, Prachi Motiyani","doi":"10.1007/s44192-025-00198-2","DOIUrl":"10.1007/s44192-025-00198-2","url":null,"abstract":"<p><p>The intricate relationship between substance addiction and mental health among India's prison population is a formidable task for these institutions. These disorders include psychotic illness, neurotic disorders, substance abuse, personality disorders, and mood disorders. High levels of depression and anxiety, in which substance addiction and mental illness frequently coexist, exacerbate the issue and worsen the outlook for those who are affected. In India, there are many obstacles in the way of inmates with mental health issues facing inappropriate care and inadequate medication administration within the prison system. There are still gaps in the quality of care for people with mental health concerns since the integration of jail health services with the larger National Health Service is still being worked out. A further layer of complexity is created by the proliferation of novel psychoactive substances in prisons, as more research is needed to determine how these drugs affect prisoners mental health. Another area of concern is the disproportionate impact that substance misuse and mental health disorders have on female convicts in India. Research has repeatedly demonstrated that women in prison have greater rates of drug abuse and depression, underscoring the need for assistance and interventions tailored to each gender. One major reason is the inadequate counselling and treatment available in prison which is due to the lack of staff, training and over crowdedness of prisoners. A more thorough and integrated approach is required to solve this complex issue by initiating mental health counselling and treatment plans including de-addiction centres and providing good medical assistance to all irrespective of gender discrimination and barriers to assessing care. This study will highlight the issues that substance abuse causes for prisoners, including how it affects their mental health and will offer various policies and recommendations for the same.</p>","PeriodicalId":72827,"journal":{"name":"Discover mental health","volume":"5 1","pages":"76"},"PeriodicalIF":0.0,"publicationDate":"2025-05-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12098245/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144129594","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Spiritual well-being mediates between psychological capital and emotional experiences: evidence from college students at a private residential university in India.","authors":"Jerin V Philipose, Rajneesh Choubisa, Akash Dubey","doi":"10.1007/s44192-025-00203-8","DOIUrl":"10.1007/s44192-025-00203-8","url":null,"abstract":"<p><p>College students worldwide are encountering significant mental health challenges and positive psychological approaches are effective in addressing these issues. Psychological capital as a construct having origin from organizational psychology plays an important role in young people's education and mental health. The dimensions of psychological capital and spiritual well-being play an important role in manifesting emotional experiences, both positive and negative, among young individuals. In the contemporary scenario, where social and economic factors act as deciding factors in deciphering and influencing emotions, there is a dire need to focus on the positive developmental aspects of human behavior. We, thus, explore the interconnection between psychological capital and spiritual well-being and quantitatively investigate how both of them influence the emotional experiences of college students (N = 214). Results from the regression analysis suggest that psychological capital predicts positive emotions, whereas spiritual well-being mediates this relationship. One of the practical implications of our results suggest that these three variables have good interventional potential for well-being promotion studies.</p>","PeriodicalId":72827,"journal":{"name":"Discover mental health","volume":"5 1","pages":"74"},"PeriodicalIF":0.0,"publicationDate":"2025-05-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12089015/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144103253","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Perinatal depression, perinatal mental health, and legal interventions: a medico-legal anthropological concept.","authors":"Ritika Behl","doi":"10.1007/s44192-025-00204-7","DOIUrl":"10.1007/s44192-025-00204-7","url":null,"abstract":"<p><p>Perinatal depression (PND), and perinatal mental health (PMH) are regarded as an underestimated public health concern. A doctoral study was undertaken to analyze the efficacy of existing health laws and policies in India in addressing and managing PND, and the implications of non-recognition of PND as a public health issue. The interdisciplinary and transdisciplinary study involved four disciplines: Psychiatry, Medical Anthropology, Public Health Law, and International Human Rights Law. The study highlighted the need for synergistic assimilation of knowledge from the four disciplines to read mental health, PND, and PMH. The study novelly emphasized the need to read PND as a 'medico-legal anthropological' concept, which manifests medically, results largely, and is strongly influenced by psychosocial factors, making it imperative to recognize perinatal women as a vulnerable population and safeguard their human rights. This approach will facilitate assessments about interventions for addressing and/or managing PND when policy-making/policy reforms regarding PND are in progress.</p>","PeriodicalId":72827,"journal":{"name":"Discover mental health","volume":"5 1","pages":"73"},"PeriodicalIF":0.0,"publicationDate":"2025-05-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12081797/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144082504","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}