Discover mental health最新文献

{"title":"Exploring mental health of Italian college students: a systematic review and meta-analysis.","authors":"Luca Gambolò, Roberta Pireddu, Marta D'Angelo, Elena Maria Ticozzi, Lorenzo Bellini, Daniele Solla, Nazzareno Fagoni, Giuseppe Stirparo","doi":"10.1007/s44192-025-00229-y","DOIUrl":"10.1007/s44192-025-00229-y","url":null,"abstract":"<p><strong>Introduction: </strong>The transition from adolescence to adulthood is characterized by changes and challenges for students, that can affect their mental well-being. Furthermore, mental disorders often emerge before the age of 24, underscoring the significance of addressing mental health during the college years. The study's objective is to conduct a systematic review of the mental health of Italian university students, exploring the prevalence of psychopathological dimensions, identifying risk and protective factors, and investigating the impact on academic performance.</p><p><strong>Methods: </strong>The initial search yielded 842 papers. After the screening process, a total of 27 studies were included (22,928 participants).</p><p><strong>Results: </strong>The prevalence of mental distress is notable: stress affects 72.6%, anxiety 61.8%, depression 41.6%, sleep disorders 63.9%, and suicide risk 6.1%.</p><p><strong>Discussion: </strong>Biological factors like chronic illness and family history increase the risk of psychological disorders. Psychological factors, including sexual orientation, play a role. Dysfunctional personality traits, adverse events, financial concerns, and the pandemic amplify distress. Resilience, coping strategies, peer support, inclusive environments, physical activity, and balanced lifestyles act as protective factors. Mental distress impacts academic performance and often is exacerbated by the pressure to excel. Interventions encompass targeted support, cognitive-behavioral therapy, and the promotion of inclusive and supportive environments.</p>","PeriodicalId":72827,"journal":{"name":"Discover mental health","volume":"5 1","pages":"91"},"PeriodicalIF":0.0,"publicationDate":"2025-06-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12179042/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144334535","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Exposure to pollution and climate change-induced food insecurity on depressive symptoms among adolescents in rural areas of Afghanistan.","authors":"Conrad Murendo","doi":"10.1007/s44192-025-00172-y","DOIUrl":"10.1007/s44192-025-00172-y","url":null,"abstract":"<p><strong>Background: </strong>Research into how pollution and climate change-induced food insecurity affect adolescents' mental health in Afghanistan is still in its infancy. This study analyses the association between pollution exposure, climate change-induced food insecurity and, depressive symptoms among adolescents in Afghanistan.</p><p><strong>Methods: </strong>A cross-sectional study was conducted among 1416 adolescents and their 1416 parents and/or caregivers in seven provinces of Afghanistan. Exposure to pollution and climate change-induced food insecurity are the explanatory variables of interest. Mental health was measured by the occurrence of depression. Multivariate logistic regression analysis was used for estimation.</p><p><strong>Results: </strong>The multivariate logistic regression results revealed that adolescents exposed to pollution were 2.66 times more likely to exhibit depressive symptoms (OR = 2.66; <math><mrow><mi>p</mi> <mo><</mo> <mn>0.001</mn></mrow> </math> ), and the effects were significant for both boys and girls. Adolescents experiencing climate change (drought and floods) induced food insecurity were 1.39 times more likely to exhibit depressive symptoms (OR = 1.30; <math><mrow><mi>p</mi> <mo><</mo> <mn>0.05</mn></mrow> </math> ). In addition, the study found that the effects of drought and flood induced food insecurity on mental health were pronounced among girls than boys.</p><p><strong>Conclusion: </strong>Exposure to pollution and climate change-induced food insecurity were associated with depressive symptoms among adolescents. The public, private sector, and international organizations should promote pollution, drought, and flood mitigation strategies, as these environmental factors may contribute to mental health challenges among adolescents. There is need for interventions that specifically target female adolescents given their vulnerabilities to climate change-induced food insecurity. There is scope to integrate mental health services, with food security, pollution and climate mitigation interventions in Afghanistan. Policymakers should focus on regular community-based mental health screening programs, training local mental health professionals, and educating adolescents about the symptoms of depression.</p>","PeriodicalId":72827,"journal":{"name":"Discover mental health","volume":"5 1","pages":"92"},"PeriodicalIF":0.0,"publicationDate":"2025-06-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12179013/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144334536","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Comparative child mental health and academic outcomes after primary school teachers deliver task-shifted mental health care in India.","authors":"Priscilla Giri, Molly M Lamb, Venessa C Fuentes, Arpana Thapa, Surekha Bhattarai, Choden Dukpa, Catherine C Shrestha, Setareh Ekhteraei, Juliana L Vanderburg, Breanna Windsor, Abhishek K Rauniyar, Karen Hampanda, Bradley N Gaynes, Rinzi Lama, Michael Matergia, Christina M Cruz","doi":"10.1007/s44192-025-00217-2","DOIUrl":"10.1007/s44192-025-00217-2","url":null,"abstract":"<p><p>Teachers are promising lay counselors but have limited time for traditional therapy. To viably leverage teachers to deliver care, we developed Teachers Leading the Frontlines (Tealeaf), where teachers deliver a novel therapy, \"education as mental health therapy\" (Ed-MH); measures are an extension of classroom management, not an added task. We investigated whether Tealeaf teachers improved child mental health symptoms and academic achievement versus teachers delivering an enhanced usual care (EUC) comparator, Responding to Students' Emotions through Education (RE-SEED), a truncated version of Tealeaf. We conducted a pragmatic, mixed methods, post hoc analysis using data from 2019 of an open trial of Tealeaf running in parallel with the all-EUC first step of a stepped wedge cluster randomized controlled trial (SW-CRCT). We compared postintervention child mental health symptom scores and academic achievement. Semi-structured interviews and focus groups were analyzed using inductive content analyses. Tealeaf teachers observed lower mental health symptom severity (n = 23 children in Tealeaf, n = 104 in RE-SEED; Cohen's d = 0.70; p = 0.024). Students in Tealeaf (n = 26, n = 183 in RE-SEED) performed better in math (d = 0.63; p = 0.0006) and reading (d = 0.83; p = 0.001). Caregivers of children in RE-SEED (n = 177), the comparator condition, reported lower severity of overall mental health difficulties and internalizing difficulties for their children compared to caregivers' reports of their children in Tealeaf (n = 25). Tealeaf teachers displayed a greater depth in mental health understanding in mixed methods findings. Evidence supports teachers' potential to improve child mental health and academics in school while underscoring the need for additional home-based supports. Tealeaf Clinical Trials Registry-India (CTRI) Reg. No. CTRI/2018/01/011471, Ref. No. REF/2017/11/015895; date of registration 2018-01-01. RE-SEED TRN NCT04723277; date of registration 2021-01-25.</p>","PeriodicalId":72827,"journal":{"name":"Discover mental health","volume":"5 1","pages":"90"},"PeriodicalIF":0.0,"publicationDate":"2025-06-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12176721/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144327964","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Panacea for improving mental health: the influential roles of social capital, resilience and job embeddedness on nurses' mental health.","authors":"Obinna O Ike, Ngozi U Chuke, Onyedikachi C Nnamchi","doi":"10.1007/s44192-025-00222-5","DOIUrl":"10.1007/s44192-025-00222-5","url":null,"abstract":"<p><strong>Background: </strong>Given the high demands and stressors associated with the profession, mental health issues among nurses have become a growing concern. Nurses frequently encounter a combination of emotional, physical, and mental challenges that contribute to burnout, anxiety, depression, and other mental-health problems. Limited research has addressed the endogenous and exogenous precipitating factors that influence mental health among healthcare professionals, particularly nurses, in the healthcare sector. However, addressing mental health concerns among nurses is crucial for their well-being and the quality of care they provide. This study investigated the influence of social capital, resilience, and job embeddedness on positive mental health among nurses.</p><p><strong>Methods: </strong>This study employed a cross-sectional design, involving 613 nurses aged 29-55 years (M = 34.78, SD = 6.52) recruited through snowball sampling from government-owned hospitals in Southeast Nigeria. Data were collected via an online survey utilizing standardized measures, including the Personal Social Capital Scale, Brief Resilience Scale, Global Job Embeddedness Scale, and Positive Mental Health Scale. Hierarchical multiple regression was used for the data analysis. The STROBE checklist guidelines were used to ensure quality and transparency.</p><p><strong>Results: </strong>Hierarchical multiple regression analysis was conducted to test the hypotheses. Results revealed that Social capital (β = .27; t = 2.29, p < .05), resilience (β = .30; t = 4.40, p < .05), and job embeddedness (β = .21; t = 3.37, p < .05) were independently and positively correlated with positive mental health among the nurses.</p><p><strong>Conclusions: </strong>The study findings revealed that social capital, resilience, and job embeddedness are recipes for enhancing and harnessing positive mental health among nurses. The findings of this study underscore the intricate interplay between these endogenous and exogenous factors-job embeddedness, social capital, and resilience-in promoting mental health among nurses in their organizational context. These factors emerge as critical elements that facilitate employees' capacity to navigate workplace challenges and mitigate stressors that may affect their mental wellbeing.</p>","PeriodicalId":72827,"journal":{"name":"Discover mental health","volume":"5 1","pages":"89"},"PeriodicalIF":0.0,"publicationDate":"2025-06-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12174030/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144318797","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Emerging and accumulating safety signals for the use of estrogen among transgender women.","authors":"Lauren Schwartz, M Lal, J Cohn, Carrie D Mendoza, Leslie MacMillan","doi":"10.1007/s44192-025-00216-3","DOIUrl":"10.1007/s44192-025-00216-3","url":null,"abstract":"<p><p>Efforts to alleviate the psychological distress of gender dysphoria have included the use of exogenous estrogen (often with anti-androgens) to alter secondary sex characteristics of natal males. In response to the rapid increase in presenting cases among young people, extensive scrutiny has now been brought to bear on these medical interventions for minors, with ESCAP reporting \"an urgent need for safeguarding clinical, scientific, and ethical standards.\" However, due to the lack of systematic outcome data, the associated risk-benefit profile is unknown. Several recent systematic reviews have found the evidence of benefit to be of low or very low certainty, while some risks, such as infertility, have been long recognized. This paper compiles several emerging and accumulating safety signals in the medical literature. These range from increased rates of previously associated adverse outcomes with long-term estrogen use (e.g., acute cardiovascular events) to associations of estrogen use with newly identified adverse outcomes. Estrogen also induces changes in the brain, raising concerns for negative impacts on mood (e.g., depression) and cognition. These safety signals indicate the need for further investigation and a thorough systematic search for others, which may now be more evident due to the increased number of young people receiving these treatments. There is an urgent need for the evidence base to be improved with more studies, especially those with systematic long-term follow-up and those that can disentangle possible confounders, as well as systematic reviews to help interpret their reliability.</p>","PeriodicalId":72827,"journal":{"name":"Discover mental health","volume":"5 1","pages":"88"},"PeriodicalIF":0.0,"publicationDate":"2025-06-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12162459/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144287427","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Awareness and involvement of Nigerian Family Physicians in WHO's Mental Health Gap Action Programme: a qualitative study.","authors":"Olumide Thomas Adeleke, Wulaimat Abimbolanle Adekunle, Oludaisi Adeshina Oduniyi, Akeem Opeyemi Akinbode, Alarape Naomi Oluwasanya, Omorovbiye Aibangbee, Eloho Joy Orji, Temitayo Olabode Aderemi, Adekunle Joseph Ariba","doi":"10.1007/s44192-025-00221-6","DOIUrl":"10.1007/s44192-025-00221-6","url":null,"abstract":"<p><strong>Background: </strong>The World Health Organization's Mental Health Gap Action Programme (mhGAP) intervention guide (IG) offers evidence-based recommendations and instruments for evaluating and comprehensive care of priority disorders. Its objective is to close the mental health gap; yet, this gap remains, characterized by substantial differences in access to and quality of care. Family physicians are essential in bridging this gap; nevertheless, their awareness and engagement in executing mhGAP remain ambiguous. This study explored family physicians' awareness and involvement levels in the implementation of mental health services in Nigeria as well as the perceived facilitators and barriers affecting their participation in the \"Mental Health Gap Action Programme\".</p><p><strong>Methods: </strong>This study employed a descriptive participatory action research design, utilizing semi-structured key informant interviews with 24 family physicians nationwide, representing all six geopolitical zones. Interviews were transcribed verbatim and analysed using inductive coding and content analysis, revealing key themes and patterns that informed the study's findings, which were represented thematically.  RESULTS: Family physicians demonstrated varying awareness of mental health guidelines and interventions. Involvement levels ranged from minimal to proactive as there was no national unified guide. Facilitators to mhGAP involvement and implementation included training of physicians, patient relationships, and multidisciplinary collaboration while barriers included time constraints, stigma, and systemic gaps.</p><p><strong>Conclusions: </strong>This study reveals the varying levels of mhGAP awareness and involvement among Nigerian family physicians. While some are proactive, many show limited engagement. Training, patient relationships, and collaboration facilitate involvement, while time constraints, stigma, and systemic gaps hinder it. Targeted interventions are needed to bridge the mental health action gap.</p>","PeriodicalId":72827,"journal":{"name":"Discover mental health","volume":"5 1","pages":"87"},"PeriodicalIF":0.0,"publicationDate":"2025-06-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12162395/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144276922","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Mediating effect of risk propensity between impulsivity and psychotic experiences among Lebanese young adults.","authors":"Lea Kanbar, Diana Malaeb, Fouad Sakr, Mariam Dabbous, Feten Fekih-Romdhane, Souheil Hallit, Sahar Obeid","doi":"10.1007/s44192-025-00223-4","DOIUrl":"10.1007/s44192-025-00223-4","url":null,"abstract":"<p><strong>Background: </strong>Psychotic experiences pose a significant public health concern among young adults. These subclinical symptoms can disrupt daily functioning and are often linked to risk propensity. Impulsivity, a multidimensional construct involving traits such as sensation seeking and lack of premeditation, has been implicated in various psychopathologies, including psychotic disorders. This study investigates the mediating role of risk propensity in the relationship between impulsivity and psychotic experiences among Lebanese young adults.</p><p><strong>Methods: </strong>It was a cross-sectional study conducted with 433 participants recruited through a snowball sampling technique. The following scales have been used: General Risk Propensity scale (GRiPS), Prodromal Questionnaire-Brief scale (PQ-B), and Impulsive Behavior Short Scale-8 (I-8).</p><p><strong>Results: </strong>The results of this mediation analysis revealed that risk propensity fully mediated the relationship between impulsivity and psychotic experiences (indirect effect: Beta = 0.08, Boot SE = 0.02; 95% CI 0.04; 0.11). Higher impulsivity was significantly associated with increased engagement in risk propensity, which, in turn, was significantly associated with greater severity of psychotic experiences. Direct association between impulsivity and psychotic experiences was not significant.</p><p><strong>Conclusion: </strong>These findings highlight the pivotal role of risk propensity in the link between impulsivity and psychotic experiences among Lebanese adults. Future research should explore longitudinal designs to establish causality and investigate intervention strategies aimed at reducing risk propensity to mitigate the impact of impulsivity on psychotic symptoms.</p>","PeriodicalId":72827,"journal":{"name":"Discover mental health","volume":"5 1","pages":"85"},"PeriodicalIF":0.0,"publicationDate":"2025-06-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12151974/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144259459","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Exploring mental health in Iranian children: insights from a cohort dataset by using the strengths and difficulties questionnaire.","authors":"Sulmaz Ghahramani, Mona Torkaman Cheh, Ahmad Nemati, Mohammad Sayari, Kamran Bagheri Lankarani","doi":"10.1007/s44192-025-00228-z","DOIUrl":"10.1007/s44192-025-00228-z","url":null,"abstract":"<p><strong>Introduction: </strong>This study examines the mental health of Iranian children aged 9-12 by evaluating data extracted from a cohort dataset that includes various variables from pregnancy to the mentioned age.</p><p><strong>Method: </strong>Data from the Fars Birth Cohort (FBC) was used, involving 714 children aged 9-12 in 2021. The study recorded various characteristics, including parental sociodemographics and child health, and assessed behavioral difficulties using the Strengths and Difficulties Questionnaire (SDQ) through parent-reported phone interviews. A multivariate logistic regression model identified factors linked to SDQ scores, categorized as normal or borderline/abnormal.</p><p><strong>Results: </strong>The average age of participants was 10.06 years, with a majority being girls (51.68%). Breastfeeding varied, with 42.30% breastfeeding for 4-6 months. Physical health was generally good, although common diagnoses included allergies (12.04%) and anemia (12.61%). Mental health evaluations indicated that 3.08% of children were diagnosed with depression or anxiety, while 2.52% were identified as having ADHD. Additionally, 94.96% of participants reported using technology for at least one hour daily. In terms of SDQ scores, 10.78% and 13.16% of children fell into the \"Borderline\" and \"Abnormal\" categories, respectively. Among subscales, the highest percentage of children scored within the \"normal\" range for prosocial behavior, while the highest proportion for the \"abnormal\" was emotional difficulties. Higher education levels of fathers (OR = 6.95), household smoking (OR = 1.89), ADHD diagnoses (OR = 22.87), and frequent technology use (OR = 3.92) were all significantly associated with increased abnormal scores. Also, child's age was a predictor of higher odds of an abnormal SDQ score (OR = 1.77).</p><p><strong>Conclusion: </strong>The study highlights complex relationships among parental, environmental, and child-specific factors affecting childhood behavioral difficulties. It underscores the need for comprehensive interventions targeting multiple risk factors, particularly household smoking, hyperactivity, and excessive technology use.</p>","PeriodicalId":72827,"journal":{"name":"Discover mental health","volume":"5 1","pages":"86"},"PeriodicalIF":0.0,"publicationDate":"2025-06-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12151934/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144259458","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Social context in the development of problematic gaming habits: a narrative exploration.","authors":"Benediktas Gelūnas","doi":"10.1007/s44192-025-00220-7","DOIUrl":"10.1007/s44192-025-00220-7","url":null,"abstract":"<p><p>This qualitative study explores the development of problematic gaming habits outside of the dominant diagnostic framework of gaming addiction, synthesizing insights from narrative interviews with 30 adult males recruited from the online community \"Stop Gaming\". Participants revealed diverse patterns of early gaming experiences, influenced by family and peer dynamics. Problematic gaming emerged as a coping mechanism during stressful life periods, defined by factors such as social isolation, lack of direction, or health issues. Game-intrinsic attractions such as professional ambitions, the feeling of productivity, and safety from real risk also played significant roles in intensifying gaming habits. The findings challenge the conventional addiction model by highlighting how the development of problematic gaming habits is dependent on social and cultural factors. The study emphasizes the need to address underlying circumstances when it comes to understanding and managing the personal and social distress associated with problematic gaming.</p>","PeriodicalId":72827,"journal":{"name":"Discover mental health","volume":"5 1","pages":"84"},"PeriodicalIF":0.0,"publicationDate":"2025-06-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12144011/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144251153","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The impact of epidermolysis bullosa on quality of life and mental health.","authors":"Guilherme Martins Freitas, Louise Hernandes Claure, Fabiana Antunes de Andrade, Kátia Sheylla Malta Purim","doi":"10.1007/s44192-025-00209-2","DOIUrl":"10.1007/s44192-025-00209-2","url":null,"abstract":"<p><strong>Introduction: </strong>Epidermolysis bullosa (EB) is a rare, chronic, incurable, multisystemic genetic disorder characterized by skin fragility, resulting in blistering from minimal trauma or spontaneously. Despite its physical impact, little is known about the mental health and quality of life (QoL) of those affected. This study aims to investigate these aspects in individuals with EB.</p><p><strong>Methods: </strong>A cross-sectional study was conducted in Brazil using a self-administered questionnaire and a convenience sample. Data on clinical-epidemiological characteristics, QoL (DLQI-BRA and QoLEB), and depression indicators (PHQ-9) were collected. Descriptive statistics and the Chi-square test were used, with a significance level of p < 0.05.</p><p><strong>Results: </strong>The sample consisted of 31 patients, predominantly women (89.3%), with a mean age of 33.32 ± 11.3 years. The recessive dystrophic subtype was most common (54.8%), and depressive symptoms were present in 71%. PHQ-9 results revealed 29% had \"mild depression,\" 16.1% \"moderate depression,\" 22.6% \"moderately severe depression,\" and 3.2% \"severe depression.\" QoLEB indicated significant impairment in functional domains, while DLQI showed that 45.2% of patients experienced severe QoL impact. The most affected domains were leisure, symptoms and feelings, and daily activities.</p><p><strong>Conclusion: </strong>The findings highlight the substantial impact of EB on mental health, QoL, and personal relationships. These results reinforce the need for early mental health screening and the integration of multidisciplinary care to optimize patient outcomes. Implementing structured psychological support, along with comprehensive dermatological and medical management, could mitigate the burden of the disease and enhance the overall well-being of affected individuals.</p>","PeriodicalId":72827,"journal":{"name":"Discover mental health","volume":"5 1","pages":"83"},"PeriodicalIF":0.0,"publicationDate":"2025-06-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12133663/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144210398","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}