Diabetology最新文献_第5页

Dietary Sugars during Critical Phases of Development and Long-Term Risk of Non-Communicable Diseases 发育关键阶段的膳食糖和非传染性疾病的长期风险

Diabetology Pub Date : 2023-06-25 DOI: 10.3390/diabetology4030021

M. D. Ferreira-Junior, K. N. Cavalcante, Ariel Penha Carvalho da Mota, R. Gomes

引用次数: 0

Development of a Modified Global Physical Activity Questionnaire and Its Construct Validity among Adults in Kerala, India 印度喀拉拉邦成人改良的全球身体活动问卷编制及其结构效度

Diabetology Pub Date : 2023-06-20 DOI: 10.3390/diabetology4020020

Thirunavukkarasu Sathish, Elezebeth Mathews

{"title":"Development of a Modified Global Physical Activity Questionnaire and Its Construct Validity among Adults in Kerala, India","authors":"Thirunavukkarasu Sathish, Elezebeth Mathews","doi":"10.3390/diabetology4020020","DOIUrl":"https://doi.org/10.3390/diabetology4020020","url":null,"abstract":"There is a need for a modified Global Physical Activity Questionnaire (GPAQ) to estimate physical activity levels more accurately in populations. We aimed to develop a modified GPAQ and examine its construct validity among adults in Kerala, India. We incorporated locality-specific, metabolic equivalent task (MET)-based activities into the original GPAQ and administered this modified GPAQ among randomly selected 451 individuals (age ≥ 20 years) residing in the Trivandrum district of Kerala. Construct validity of the modified GPAQ was assessed using generalized linear models by examining the association of total moderate-to-vigorous physical activity (MVPA) MET-minutes per week with clinical measures. The mean age of participants was 45.4 (SD: 14.1) years, and 52.6% were female. Increasing total MVPA MET-minutes per week was associated with decreasing weight (β = −0.011 kg, 95% CI: −0.020, −0.002), waist circumference (β = −0.013 cm, 95% CI: −0.023, −0.004), and systolic blood pressure (β = −0.009 mmHg, 95% CI: −0.015, −0.002), independent of age, sex, education, occupation, current smoking, current alcohol use, and fruit and vegetable intake. The validity coefficients and associations between total MVPA MET-minutes per week and theoretical constructs of physical activity agreed with those predicted, providing evidence of construct validity for the modified GPAQ.","PeriodicalId":72798,"journal":{"name":"Diabetology","volume":"94 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-06-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135187533","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Diabetes Mellitus Management: An Extensive Review of 37 Medicinal Plants 糖尿病管理:37种药用植物的广泛综述

Diabetology Pub Date : 2023-06-12 DOI: 10.3390/diabetology4020019

Khwaja Zohura Zanzabil, Md. Sabbir Hossain, Md. Kamrul Hasan

{"title":"Diabetes Mellitus Management: An Extensive Review of 37 Medicinal Plants","authors":"Khwaja Zohura Zanzabil, Md. Sabbir Hossain, Md. Kamrul Hasan","doi":"10.3390/diabetology4020019","DOIUrl":"https://doi.org/10.3390/diabetology4020019","url":null,"abstract":"Plants have been used as sources of medicine since ancient times. Natural products have been used extensively in Chinese, ayurvedic and folk medicine. In addition, a significant portion of the world’s population still utilizes herbal medicine. Diabetes is a common ailment affecting almost 463 million people in the world. However, current medications exert harmful after-effects on patients, while herbal medicines have fewer adverse effects. Plants possess secondary metabolites, such as alkaloids, flavonoids, tannins, steroids, etc., which exert numerous beneficial effects on health. Extensive research has been conducted over the years investigating and proving the hypoglycemic potential of various plants. The present paper reviews 37 such plants that are rich in phytoconstituents that possess a variety of pharmacological activities and have been experimentally proven to possess potentially hypoglycemic properties in animal models: Ficus racemosa, Agremone mexicana, Bombax ceiba, Cajanus cajan, Coccinia cordifolia, Momordica charantia, Syzygium cumini, Neolamarckia cadamba, Mangifera indica, Cocos nucifera, Tamarindus indica, Punica granatum, Azadirachta indica, Costus speciosus, Moringa oleifera, Andrographis paniculata, Ficus benghalensis, Anacardium occidentale, Annona squamosa, Boerhaavia diffusa, Catharanthus roseus, Cocculus hirsutus, Ficus hispida, Terminalia chebula, Terminalia catappa, Amaranthus tricolor, Blumea lacera, Piper betle leaves, Achyranthes aspera, Kalanchoe pinnata, Nelumbo nucifera, Mikania cordata, Wedelia chinensis, Murraya koenigii, Aloe barbadensis, Bryophyllum pinnatum and Asparagus racemosus. These 37 plant extracts exhibit antidiabetic activities through different mechanisms, including α-amylase and α-glucosidase inhibition, increases in glucose uptake and the stimulation of insulin secretion.","PeriodicalId":72798,"journal":{"name":"Diabetology","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-06-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"89607377","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

Nutritional Modulation of Dietary Sugars as a Strategy to Improve Insulin Resistance and Energy Balance in Diabetes 膳食糖的营养调节作为改善糖尿病胰岛素抵抗和能量平衡的策略

Diabetology Pub Date : 2023-06-10 DOI: 10.3390/diabetology4020018

P. Matafome

引用次数: 0

Impact of Dietary Sugars on β-Cell Function 膳食糖对β细胞功能的影响

Diabetology Pub Date : 2023-05-01 DOI: 10.3390/diabetology4020017

A. Malta, L. Saavedra, S. Raposo, Gabriel kian Guimarães Lopes, Maryana Debossan Fernandes, L. Barbosa, D. Almeida, P. C. F. Mathias

引用次数: 0

Feasibility and Acceptability of a Cognitive Training Study in Individuals with Type 2 Diabetes Mellitus 2型糖尿病患者认知训练研究的可行性和可接受性

Diabetology Pub Date : 2023-04-19 DOI: 10.3390/diabetology4020016

Sam Cooke, K. Pennington, C. Bridle, Ffion Curtis

{"title":"Feasibility and Acceptability of a Cognitive Training Study in Individuals with Type 2 Diabetes Mellitus","authors":"Sam Cooke, K. Pennington, C. Bridle, Ffion Curtis","doi":"10.3390/diabetology4020016","DOIUrl":"https://doi.org/10.3390/diabetology4020016","url":null,"abstract":"Individuals with type 2 diabetes mellitus (T2DM) are at an increased risk of cognitive dysfunction. Growing evidence supports the use of cognitive training to target cognitive dysfunction in T2DM, but only limited evidence exists surrounding its feasibility and acceptability. The primary aim of this research is to determine the feasibility and acceptability of a cognitive training study in T2DM. Adults diagnosed with T2DM were randomly allocated to either a 6-week cognitive training group or a usual care control group. Feasibility outcomes (recruitment, adherence, retention, motivation, data collection, and intervention design) were evaluated using a traffic light progression criterion. Qualitative interviews were conducted to explore study acceptability. Cognition was measured at baseline and post-intervention. Forty-one participants completed the study (age 66 ± 9.8 years; HbA1c 54.0 ± 13.3 mmol.mol). Feasibility was shown in the adherence, retention, and motivation of participants, whilst minor amendments were proposed to the study design, recruitment, and data collection. Participants described cognitive training as highly enjoyable, with study components broadly reported as acceptable. Data signalled improvements in cognition, with large improvements observed in executive function. This study provides evidence for the potential feasibility, acceptability, and efficacy for cognitive training in T2DM. Recommendations for future studies are provided.","PeriodicalId":72798,"journal":{"name":"Diabetology","volume":"47 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-04-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"86015094","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Progress in Understanding Metabolic Syndrome and Knowledge of Its Complex Pathophysiology 代谢综合征及其复杂病理生理的研究进展

Diabetology Pub Date : 2023-04-12 DOI: 10.3390/diabetology4020015

Birendra Kumar Jha, Mingma Lhamu Sherpa, Mohammad Imran, Yousuf Mohammed, Laxmi Akhileshwar Jha, Keshav Raj Paudel, Saurav Kumar Jha

{"title":"Progress in Understanding Metabolic Syndrome and Knowledge of Its Complex Pathophysiology","authors":"Birendra Kumar Jha, Mingma Lhamu Sherpa, Mohammad Imran, Yousuf Mohammed, Laxmi Akhileshwar Jha, Keshav Raj Paudel, Saurav Kumar Jha","doi":"10.3390/diabetology4020015","DOIUrl":"https://doi.org/10.3390/diabetology4020015","url":null,"abstract":"The metabolic syndrome (MetS), first introduced by Haller in 1975, was sometimes also known as insulin resistance syndrome, syndrome X, and plurimetabolic syndrome. In 1989, it was rechristened by Kaplan as the “Deadly Quartet” based on a consolidation of central obesity, impaired glucose tolerance, dyslipidemia, and systemic hypertension. MetS is positively associated with a pro-inflammatory and pro-thrombotic state, attributed to increased pro-thrombotic and inflammatory marker activity. Moreover, MetS is frequently associated with increased atherosclerotic cardiovascular disease, impaired glucose tolerance, hyperuricemia, obstructive sleep apnea, and chronic kidney disease. Despite concerted endeavors worldwide, the complexity of the pathophysiology of metabolic syndrome still needs to be clearly understood. Currently, therapeutic possibilities are confined to individual therapy for hyperglycemia, hypertension, hypertriglyceridemia, hyperuricemia, regular physical exercise, and a restricted diet. In this review, progress regarding the understanding and pathophysiology of MetS; recent emerging technologies, such as metabolomics and proteomics; the relation of MetS with obesity, diabetes, and cardiovascular diseases; and the association of MetS with COVID-19 are discussed.","PeriodicalId":72798,"journal":{"name":"Diabetology","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-04-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"134953262","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

Increasing the Representation of Women in Diabetes Research 增加女性在糖尿病研究中的代表性

Diabetology Pub Date : 2023-03-30 DOI: 10.3390/diabetology4020014

K. Riches-Suman

引用次数: 0

Lipodystrophies from Insulin Injection: An Update of the Italian Consensus Statement of AMD-OSDI Study Group on Injection Technique 胰岛素注射引起的脂肪营养不良:AMD-OSDI研究组关于注射技术的意大利共识声明的更新

Diabetology Pub Date : 2023-03-03 DOI: 10.3390/diabetology4010013

S. Gentile, E. Satta, G. Guarino, F. Strollo

{"title":"Lipodystrophies from Insulin Injection: An Update of the Italian Consensus Statement of AMD-OSDI Study Group on Injection Technique","authors":"S. Gentile, E. Satta, G. Guarino, F. Strollo","doi":"10.3390/diabetology4010013","DOIUrl":"https://doi.org/10.3390/diabetology4010013","url":null,"abstract":"The causes and metabolic consequences of lipohypertrophy (LH) from incorrect insulin injection techniques have been well-known for a long time and are the subject of countless publications. However, only some researchers propose structured research modalities for LH and programs to teach patients how to prevent them and minimize their effects, thus contributing to complete rehabilitation. Experts and scientific societies have produced consensus documents and recommendations to spread the culture of LH and its complications among clinicians. However, they should go deeper into LH detection methods. This short article analyzes the recent literature on the best way to explore and find more or less evident LH lesions by using a structured and validated clinical methodology to benefit the many clinicians without access to technological equipment such as ultrasonography. This text also aims to bring awareness that since the last published recommendations on injection techniques, new needles for insulin injection, more technologically advanced and suitable for specific populations, have come to market but still need a thorough evaluation.","PeriodicalId":72798,"journal":{"name":"Diabetology","volume":"22 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-03-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"81831208","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

Diabetes Management in Danish Primary School: A Survey of Experiences of Parents of Children with Type 1 Diabetes 丹麦小学糖尿病管理:1型糖尿病儿童家长的经验调查

Diabetology Pub Date : 2023-03-02 DOI: 10.3390/diabetology4010012

M. Iken, N. C. Mateu, L. Johansen, K. A. Pilgaard, A. K. Mouritsen, A. Schou, Line S. Høst, A. Ø. Nannsen, Kurt Kristensen, S. Hangaard, M. Madsen, D. Grabowski

{"title":"Diabetes Management in Danish Primary School: A Survey of Experiences of Parents of Children with Type 1 Diabetes","authors":"M. Iken, N. C. Mateu, L. Johansen, K. A. Pilgaard, A. K. Mouritsen, A. Schou, Line S. Høst, A. Ø. Nannsen, Kurt Kristensen, S. Hangaard, M. Madsen, D. Grabowski","doi":"10.3390/diabetology4010012","DOIUrl":"https://doi.org/10.3390/diabetology4010012","url":null,"abstract":"Supporting diabetes self-care in school is important for optimal glycemic control and mental health. The aim of this study was to investigate parental experiences of diabetes management in Danish schools, with an emphasis on the importance of school staff support in self-care. This cross-sectional study surveyed parents of schoolchildren with type 1 diabetes aged 6 to 16 years in Denmark. The parents were identified among members of the Danish Diabetes Association and were invited to complete an online questionnaire. A total of 252 parents of schoolchildren with type 1 diabetes answered the questionnaire. Only 28% of the children had a designated staff member responsible for support in diabetes self-care during school hours. Having a designated staff member responsible for support in self-care was positively associated with parental experiences of better school–parent cooperation (p < 0.001), better experience of diabetes management in school (p < 0.001), and larger proportions of children and parents feeling comfortable in school (p = 0.022 and p = 0.049, respectively). School staff support was positively associated with better parental experience of diabetes management and with some parameters of mental health in schoolchildren with type 1 diabetes and their parents in Denmark.","PeriodicalId":72798,"journal":{"name":"Diabetology","volume":"178 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-03-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"74877637","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1