Diabetology最新文献_第6页

Achieving Remission in the Era of Clinical Inertia: What Is Preventing Us from Treating Type 2 Diabetes? 在临床惰性时代实现缓解:是什么阻碍了我们治疗2型糖尿病?

Diabetology Pub Date : 2023-02-24 DOI: 10.3390/diabetology4010011

A. Suits, Ridhi R. Gudoor, J. Shubrook

引用次数: 0

Managing Hospitalized Patients Taking SGLT2 Inhibitors: Reducing the Risk of Euglycemic Diabetic Ketoacidosis 管理服用SGLT2抑制剂的住院患者:降低血糖型糖尿病酮症酸中毒的风险

Diabetology Pub Date : 2023-02-21 DOI: 10.3390/diabetology4010010

Julia Selwyn, Ariana R. Pichardo-Lowden

引用次数: 3

Knowledge of Diabetes among Adults at High Risk for Type 2 Diabetes in the Trivandrum District of Kerala, India 印度喀拉拉邦Trivandrum地区2型糖尿病高危人群的糖尿病知识

Diabetology Pub Date : 2023-02-16 DOI: 10.3390/diabetology4010009

T. Sathish, K. Thankappan, Jeemon Panniyammakal, B. Oldenburg

{"title":"Knowledge of Diabetes among Adults at High Risk for Type 2 Diabetes in the Trivandrum District of Kerala, India","authors":"T. Sathish, K. Thankappan, Jeemon Panniyammakal, B. Oldenburg","doi":"10.3390/diabetology4010009","DOIUrl":"https://doi.org/10.3390/diabetology4010009","url":null,"abstract":"We aimed to study the knowledge of diabetes among individuals with a high risk for developing type 2 diabetes in the Trivandrum district of the Indian state of Kerala. The baseline data collected from 1007 participants of the Kerala Diabetes Prevention Program were analyzed. Diabetes knowledge was assessed using a scale adapted from a large nationwide study conducted in India. The composite score of the scale ranged from 0 to 8. The mean age of the participants was 46.0 (SD: 7.5) years, and 47.2% were women. The mean diabetes knowledge score was 6.9 (SD: 2.1), with 59.5% having the maximum possible score of 8. Of the 1007 participants, 968 (96.1%) had heard the term diabetes, and of them, 87.2% knew that the prevalence of diabetes is increasing, 92.9% knew at least one risk factor for diabetes, 79.6% knew that diabetes can cause complications in organs, and 75.9% knew that diabetes can be prevented. While the overall level of knowledge of diabetes about its risk factors, complications, and prevention was generally high, an alarmingly low proportion of participants knew that diabetes can affect key organs such as the eyes (24.0%), heart (20.1%), feet (10.2%), and nerves (2.9%), and nearly a quarter (24.1%) were not aware that diabetes can be prevented. It is essential to educate high-risk individuals about diabetes complications and the importance of and strategies for diabetes prevention in the Trivandrum district of Kerala.","PeriodicalId":72798,"journal":{"name":"Diabetology","volume":"54 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-02-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"81916796","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The Lipids and Volume in Satiation and Satiety (LIVES) Hypothesis: A Proposed Alternative Model for the Pathogenesis of Obesity 饱腹和饱腹的脂质和体积(LIVES)假说:肥胖发病机制的另一种建议模型

Diabetology Pub Date : 2023-02-14 DOI: 10.3390/diabetology4010008

A. Warrilow, K. Pumpa, S. Somerset, N. Naumovski

{"title":"The Lipids and Volume in Satiation and Satiety (LIVES) Hypothesis: A Proposed Alternative Model for the Pathogenesis of Obesity","authors":"A. Warrilow, K. Pumpa, S. Somerset, N. Naumovski","doi":"10.3390/diabetology4010008","DOIUrl":"https://doi.org/10.3390/diabetology4010008","url":null,"abstract":"Obesity is one of the most important factors responsible for the marked increase in both the incidence and prevalence of type 2 diabetes mellitus (T2DM) in recent decades. Addressing the lifestyle factors associated with the progression to T2DM would present a potential rational early prevention strategy. The current evidence suggests that excessive energy intake is mediated via dietary fat. Biochemical signals released in response to the ingestion of food require supportive signalling from the presence of food in the stomach. The degree of supportive volume signalling emanating from the stomach influences both the satiation and satiety phases. The Lipids and Volume in Satiation and Satiety (LIVES) Hypothesis proposes that the biological feedback from fat intake appears to be influenced by the other macronutrients with which it is consumed. By identifying the various possible macronutrient combinations with fat, it is possible to construct a matrix of food composition/volume scenarios, which may help elucidate dysfunction in the human food energy regulation system within the context of the modern food environment.","PeriodicalId":72798,"journal":{"name":"Diabetology","volume":"82 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-02-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"82401684","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

Editorial to “Gender Differences in Diabetes” 《糖尿病的性别差异》社论

Diabetology Pub Date : 2023-02-03 DOI: 10.3390/diabetology4010007

G. Tonolo

引用次数: 0

Transitioning to Telehealth during COVID-19: Experiences and Insights from Diabetes Prevention and Management Program Providers in Los Angeles County 2019冠状病毒病期间向远程医疗过渡:洛杉矶县糖尿病预防和管理项目提供者的经验和见解

Diabetology Pub Date : 2023-01-31 DOI: 10.3390/diabetology4010006

S. Bullock, Telma Menendez, Liz Schwarte, Lisa Craypo, Jennifer T. Mosst, Gabrielle Green, N. Barragan, T. Kuo

{"title":"Transitioning to Telehealth during COVID-19: Experiences and Insights from Diabetes Prevention and Management Program Providers in Los Angeles County","authors":"S. Bullock, Telma Menendez, Liz Schwarte, Lisa Craypo, Jennifer T. Mosst, Gabrielle Green, N. Barragan, T. Kuo","doi":"10.3390/diabetology4010006","DOIUrl":"https://doi.org/10.3390/diabetology4010006","url":null,"abstract":"The onset of the COVID-19 pandemic in March 2020 accelerated the efforts of several organizations providing the National Diabetes Prevention Program (National DPP) and the Diabetes Self-Management Education and Support (DSMES) program to rapidly transition from in-person service delivery to program administration via telehealth. Semi-structured interviews were conducted with 35 National DPP and DSMES experts and providers in Los Angeles County to gain a better understanding of the challenges and benefits associated with this transition. Interviews were completed during June to October 2021. Thematic analyses were performed using the Social-Ecological Model as a guiding framework. The analyses revealed several factors that influenced the transition, including at the individual (e.g., technology and health behaviors), interpersonal (e.g., social connections and support), organizational (e.g., provider workload and program enrollment and retention), community (e.g., recruitment), and policy (e.g., government support and reimbursement for telehealth services) levels. Findings suggest that the transition to telehealth was challenging for most National DPP and DSMES providers. However, because of its lower cost, ability to reach long distances virtually, and potential efficiency when employed as part of a hybrid approach, this delivery modality remains viable, offering benefits beyond the traditional program models.","PeriodicalId":72798,"journal":{"name":"Diabetology","volume":"30 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-01-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"91120015","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 2

Acknowledgment to the Reviewers of Diabetology in 2022 对2022年《糖尿病学》审稿人的感谢

Diabetology Pub Date : 2023-01-19 DOI: 10.3390/diabetology4010004

引用次数: 0

Are Dietary Sugars Potent Adipose Tissue and Immune Cell Modulators? 膳食糖是有效的脂肪组织和免疫细胞调节剂吗?

Diabetology Pub Date : 2023-01-19 DOI: 10.3390/diabetology4010005

P. Barbosa, E. Carvalho

{"title":"Are Dietary Sugars Potent Adipose Tissue and Immune Cell Modulators?","authors":"P. Barbosa, E. Carvalho","doi":"10.3390/diabetology4010005","DOIUrl":"https://doi.org/10.3390/diabetology4010005","url":null,"abstract":"Glucose, fructose, and galactose are widely used in the food industry as sweeteners and food additives. The over-consumption of these carbohydrates has been identified as a possible trigger of non-communicable diseases. These include insulin resistance, obesity, and type 2 diabetes. These sugars induce an energy overload with consequent adipose tissue (AT) expansion, contributing to the development of obesity. Furthermore, a common feature of these non-communicable diseases is the detrimental, chronic, low-grade inflammation contributing to their onset. In the present review, we identify the most widely used dietary free sugars and their direct impacts on AT metabolism and inflammation, as well as their involvement in systemic inflammation and effects on the immune cell phenotype and function. Additionally, we discuss the capacity of the free sugars to induce immune modulation, enhancing inflammation, an underlying hallmark of insulin resistance, obesity, and T2DM. Dietary sugars have an important and deleterious metabolic impact on AT and also on immune cells. More research is needed to effectively understand the impact of chronic exposure to high levels of individual or combined sugars on metabolism, with the impact on immunomodulation being especially important.","PeriodicalId":72798,"journal":{"name":"Diabetology","volume":"68 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-01-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"90906751","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Glycemia and New-Onset Diabetes among COVID-19 Patients with Prediabetes: A Follow-Study of Case Series in India 2019冠状病毒病前驱糖尿病患者的血糖和新发糖尿病:印度病例系列的随访研究

Diabetology Pub Date : 2023-01-06 DOI: 10.3390/diabetology4010003

Nirmala Chandrasekaran, T. Sathish

{"title":"Glycemia and New-Onset Diabetes among COVID-19 Patients with Prediabetes: A Follow-Study of Case Series in India","authors":"Nirmala Chandrasekaran, T. Sathish","doi":"10.3390/diabetology4010003","DOIUrl":"https://doi.org/10.3390/diabetology4010003","url":null,"abstract":"Studies have shown that COVID-19 patients with prediabetes frequently present with high plasma glucose levels on hospital admission. However, whether the glycemic abnormalities are temporary or persist after recovery from the illness is unclear. We conducted a follow-up study of the case series of 69 COVID-19 patients with prediabetes (HbA1c 5.7–6.4%) who were admitted to a tertiary care hospital in Chennai, India, from May to October 2020 and were discharged alive. Over a mean follow-up of 146.6 (SD: 72.5) days, the mean fasting plasma glucose rose significantly by 16.8 mg/dL (from 119.3–136.1 mg/dL), 2-hr post-prandial glucose by 61.0 mg/dL (from 176.2–237.2 mg/dL), and HbA1c by 0.6% (5.9–6.5%). Of the 49 (84.5%) patients who were discharged with glucose-lowering medications, 40 (81.6%) continued taking them at the first follow-up visit (mean of 50.1 days from admission), and 39 (79.6%) continued taking them at the second follow-up visit (mean of 114.3 days from the first follow-up visit). In addition, 12.1% of patients developed new-onset diabetes after recovery from the illness. These findings underscore the importance of regular monitoring of glycemic parameters in COVID-19 patients with prediabetes after recovery.","PeriodicalId":72798,"journal":{"name":"Diabetology","volume":"220 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-01-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"81381073","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The Impact of Moderate-to-High-Intensity Exercise Protocols on Glycated Hemoglobin Levels in Type 2 Diabetes Patients 中高强度运动方案对2型糖尿病患者糖化血红蛋白水平的影响

Diabetology Pub Date : 2022-12-28 DOI: 10.3390/diabetology4010002

A. Pedrosa, G. Furtado, M. P. de Barros, A. Bachi, J. P. Ferreira, V. Sardão, L. Rama, A. Teixeira

{"title":"The Impact of Moderate-to-High-Intensity Exercise Protocols on Glycated Hemoglobin Levels in Type 2 Diabetes Patients","authors":"A. Pedrosa, G. Furtado, M. P. de Barros, A. Bachi, J. P. Ferreira, V. Sardão, L. Rama, A. Teixeira","doi":"10.3390/diabetology4010002","DOIUrl":"https://doi.org/10.3390/diabetology4010002","url":null,"abstract":"Type 2 diabetes mellitus (T2DM) is a growing global health issue that is closely linked to the epidemic of obesity. In addition to genetic factors, environmental and health-risk behaviours (i.e., high-carbohydrate diet and physical inactivity) contribute to a variety of pathophysiological disorders. Advanced exercise protocols, such as Moderate-to-intensity (MIT) and High Intensity Interval Training (HIIT), revealed a strategy for mitigating and/or attenuating the DTMII’s harmful effects by controlling glycated haemoglobin (HbA1c) levels. The goals of this review were to summarize the most recent evidence on the impact of HIIT on HbA1c levels. A mini-review protocol was performed through the PubMed/Medline database. The search comprised experimental and randomized controlled trial studies published in English between 2016 and 2021. The terms HbA1c, T2DM, MIT and HIIT, and their analogues were used. A total of seven studies were finally included. Our findings showed that the HIIT protocol is an effective strategy to induce HbA1c balance and improve glycaemic control than moderate training. The HIIT conducted in the laboratory and involving aerobic exercise on a cycle ergometer appears to be more efficient that MIT. Additional findings include improved beta-cell function, decreased low-grade inflammation, and the induction of cardiovascular benefits. More research is required to investigate the feasibility and safety of HIIT protocols in T2DM patients.","PeriodicalId":72798,"journal":{"name":"Diabetology","volume":"52 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-12-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"83955199","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1