Dermatologie (Heidelberg, Germany)最新文献_第9页

[Pyoderma gangrenosum: pathogenesis, diagnosis, and treatment]. 坏疽性脓皮病：发病机制、诊断与治疗。

Dermatologie (Heidelberg, Germany) Pub Date : 2025-07-01 Epub Date: 2025-06-23 DOI: 10.1007/s00105-025-05522-z

Joachim Dissemond, Maurice Moelleken, Alpaslan Tasdogan

{"title":"[Pyoderma gangrenosum: pathogenesis, diagnosis, and treatment].","authors":"Joachim Dissemond, Maurice Moelleken, Alpaslan Tasdogan","doi":"10.1007/s00105-025-05522-z","DOIUrl":"10.1007/s00105-025-05522-z","url":null,"abstract":"Pyoderma gangrenosum (PG) is a skin disease that rapidly develops from papules or primarily sterile pustules. It is characterized by the formation of extremely painful wounds with a reddish-livid edge and surrounding areas. It can be triggered by trauma, bacteria or drugs in genetically predisposed people. In 70% of cases, the predilection sites manifest at the extensor sides of the lower extremities. Although the exact pathophysiology of this rare neutrophilic dermatosis has not yet been fully elucidated, an autoinflammatory genesis with increased neutrophil granulocyte activity is currently being discussed. Patients often have inflammatory comorbidities such as chronic inflammatory bowel disease or cancer. To confirm the diagnosis, the validated PARACELSUS score, which summarizes the nonspecific criteria, should be used. In addition to the administration of immunosuppressive drugs such as prednisolone and/or ciclosporin, patients with proven PG are treated systemically with biologics, small molecules, or intravenous immunoglobulins. Utilization of these pharmaceutical agents has seen a marked increase in recent cases of PG. This should be accompanied by topical pharmacological treatment of the wound surroundings as well as modern wound and pain therapy.","PeriodicalId":72786,"journal":{"name":"Dermatologie (Heidelberg, Germany)","volume":" ","pages":"449-458"},"PeriodicalIF":0.0,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144478057","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

[Genital herpes, paronychia, and lymphangitis of the arm-HSV 1 as the missing link]. [生殖器疱疹，甲沟炎和手臂淋巴管炎- hsv 1作为缺失环节]。

Dermatologie (Heidelberg, Germany) Pub Date : 2025-07-01 Epub Date: 2025-03-11 DOI: 10.1007/s00105-025-05490-4

Rika Kluck, Ulrike Raap, Maike Marleen Holtsche

引用次数: 0

[Novel foods-What must be considered?] 新奇的食物——必须考虑什么？］

Dermatologie (Heidelberg, Germany) Pub Date : 2025-07-01 Epub Date: 2025-05-06 DOI: 10.1007/s00105-025-05504-1

Frédéric Toussaint, Nicola Wagner

引用次数: 0

[Eosinophilic esophagitis-an underestimated food allergy?] 嗜酸性食道炎——被低估的食物过敏？]

Dermatologie (Heidelberg, Germany) Pub Date : 2025-07-01 Epub Date: 2025-05-26 DOI: 10.1007/s00105-025-05513-0

A Hörning, A Madisch

引用次数: 0

[Food allergy as occupational disease]. 【作为职业病的食物过敏】。

Dermatologie (Heidelberg, Germany) Pub Date : 2025-07-01 Epub Date: 2025-05-26 DOI: 10.1007/s00105-025-05509-w

Julia Zarnowski, R Treudler

{"title":"[Food allergy as occupational disease].","authors":"Julia Zarnowski, R Treudler","doi":"10.1007/s00105-025-05509-w","DOIUrl":"10.1007/s00105-025-05509-w","url":null,"abstract":"Background: Food-induced allergic reactions not only occur in private settings but also in occupational context. In these cases, the presence of an occupational disease should be investigated. We provide an overview of selected food-associated occupational diseases.Methods: A literature search was conducted on food-associated occupational dermatoses (contact urticaria, protein contact dermatitis) and occupational food anaphylaxis.Results: Food allergy as an occupational disease is usually manifested as respiratory or cutaneous symptoms, while food anaphylaxis is rarely reported. Employees in food processing industries, in particular cooks and workers in the fishing and meat industry as well as employees in the bakery and pastry industries, represent a highly exposed group for food-associated occupational dermatoses, occupational asthma and food anaphylaxis.Conclusion: The possible triggers for occupational food allergies are diverse and can range from foods of animal origin (meat, fish, dairy products) to various plant-derived allergens and food additives (e.g. carmine E120, enzymes). A precise exposure history and allergological diagnostics are crucial in cases of suspected occupational food allergy.","PeriodicalId":72786,"journal":{"name":"Dermatologie (Heidelberg, Germany)","volume":" ","pages":"414-421"},"PeriodicalIF":0.0,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144144788","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

[Disseminated atrophoderma of Pasini and Pierini with blaschkoid appearance]. [伴有囊胚样外观的弥散性帕西尼和皮里尼萎缩皮病]。

IF 0.7

Dermatologie (Heidelberg, Germany) Pub Date : 2025-07-01 Epub Date: 2025-05-21 DOI: 10.1007/s00105-025-05503-2

Thilo Gambichler, Kathrin Noldes, Andrea von Stemm, Ocko Kautz, Stefanie Boms

引用次数: 0

[Training in the age of digitalization- evaluation of the digital Münster dermatopathology course]. 【数字化时代的培训——数字化<s:1> nster皮肤病理学课程评价】。

Dermatologie (Heidelberg, Germany) Pub Date : 2025-07-01 Epub Date: 2025-05-23 DOI: 10.1007/s00105-025-05516-x

Paul Schmidle, Dieter Metze, Ole Hätscher, Stephan Alexander Braun

{"title":"[Training in the age of digitalization- evaluation of the digital Münster dermatopathology course].","authors":"Paul Schmidle, Dieter Metze, Ole Hätscher, Stephan Alexander Braun","doi":"10.1007/s00105-025-05516-x","DOIUrl":"10.1007/s00105-025-05516-x","url":null,"abstract":"Background: Dermatopathology is an important component in diagnosing dermatological diseases. For more than 20 years, training courses have been offered in Münster to provide structured insight into dermatopathology. Since 2021 these courses have been offered in a digital format.Objectives: Goals were (i) to present the new digital course format, (ii) to systematically analyze the evaluation of the online courses by the participants and (iii) to discuss the general advantages and disadvantages of an increasingly digital training in dermatopathology.Materials and methods: From 2021-2024, annual online courses were evaluated by participants using a standardized questionnaire. Questions were asked about specialist title, level of training, country of origin, technical implementation of the digital format, and course content. Responses were statistically analyzed.Results: The conversion of the courses to a digital format was rated very positively overall. Participants had no problems with the technical implementation. The participants would like to see more digital courses in dermatopathology in the future and even prefer digital courses to analogue ones.Conclusion: The future also belongs to complementary digital teaching formats in dermatopathology. Our example shows that these are already technically feasible and have been consistently positively evaluated by participants. However, purely online events also have disadvantages, particularly due to the lack of personal interaction. A combination of various face-to-face and digital formats seems to be the best way forward.","PeriodicalId":72786,"journal":{"name":"Dermatologie (Heidelberg, Germany)","volume":" ","pages":"434-440"},"PeriodicalIF":0.0,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12226643/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144129395","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

[From adjuvant to neoadjuvant treatment: New options in systemic therapy for melanoma]. [从辅助治疗到新辅助治疗：黑色素瘤全身治疗的新选择]。

Dermatologie (Heidelberg, Germany) Pub Date : 2025-06-01 Epub Date: 2025-05-20 DOI: 10.1007/s00105-025-05512-1

Miriam Mengoni, Christoffer Gebhardt, Sebastian Haferkamp

引用次数: 0

Erratum zu: OMW: Leishmaniasis.

Dermatologie (Heidelberg, Germany) Pub Date : 2025-06-01 DOI: 10.1007/s00105-025-05501-4

V L Müller, M Vidakovic, A Kreuter, C Sunderkötter, E von Stebut

引用次数: 0

[Diffuse hyperpigmentation in systemic sclerosis]. 系统性硬化症的弥漫性色素沉着。

Dermatologie (Heidelberg, Germany) Pub Date : 2025-06-01 Epub Date: 2025-03-26 DOI: 10.1007/s00105-025-05494-0

Sven-Niklas Burmann, Johanna Matull, Frank Oellig, Jörg H W Distler, Alexander Kreuter, Andrea-Hermina Györfi

引用次数: 0