COVID Pub Date : 2024-02-14 DOI: 10.3390/covid4020018

Davide J. Testa, Zaheer A. S. H. Nagarwala, J. Vale, Andres E. Carrillo, Cagney T. Sargent, Sharon Amollo, Mutono Nyamai, Belén Carballo-Leyenda, B. Onyima, Ibukun Afolabi, Tiago S. Mayor, Sally Hargreaves, Marija Marković, A. Flouris

{"title":"Measuring the Impact of the Coronavirus Disease 2019 Pandemic on Mobility Aspirations and Behaviours","authors":"Davide J. Testa, Zaheer A. S. H. Nagarwala, J. Vale, Andres E. Carrillo, Cagney T. Sargent, Sharon Amollo, Mutono Nyamai, Belén Carballo-Leyenda, B. Onyima, Ibukun Afolabi, Tiago S. Mayor, Sally Hargreaves, Marija Marković, A. Flouris","doi":"10.3390/covid4020018","DOIUrl":"https://doi.org/10.3390/covid4020018","url":null,"abstract":"The coronavirus disease 2019 (COVID-19) pandemic prompted tens of thousands of people worldwide to migrate from cities in its early stages, leading to an increased spread of the virus. Understanding the factors driving relocation during a pandemic is crucial for effective outbreak control. We investigated how the pandemic influenced people’s aspirations and preparations to move, both domestically and internationally, surveying individuals in Greece, India, Italy, Kenya, Nigeria, Portugal, Serbia, Spain, and the United States of America. Out of 4448 eligible responses, 765 participants (17.2%) had a strong aspiration to move due to COVID-19, and 155 (3.5%) had already prepared. Those considering relocation were statistically significantly more likely to perceive moving to an area with fewer COVID-19 cases as protective against the virus (OR = 1.3, p < 0.05) or to know others who intended to relocate because of COVID-19 (OR = 1.5, p < 0.05). Conversely, a strong sense of being ‘at home’ reduced statistically significantly the strength of mobility aspirations (OR = 0.7, p < 0.01). Social alienation, social imitation, and the perceived efficacy of mobility increased aspirations to move due to COVID-19. This study emphasizes the rapid population movements at pandemic onset and their potential contribution to disease transmission, urging future pandemic planning to take account of such mobility dynamics.","PeriodicalId":72714,"journal":{"name":"COVID","volume":"165 ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-02-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139837684","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Measuring the Impact of the Coronavirus Disease 2019 Pandemic on Mobility Aspirations and Behaviours 衡量 2019 年冠状病毒疾病大流行对流动性愿望和行为的影响

COVID Pub Date : 2024-02-14 DOI: 10.3390/covid4020018

Davide J. Testa, Zaheer A. S. H. Nagarwala, J. Vale, Andres E. Carrillo, Cagney T. Sargent, Sharon Amollo, Mutono Nyamai, Belén Carballo-Leyenda, B. Onyima, Ibukun Afolabi, Tiago S. Mayor, Sally Hargreaves, Marija Marković, A. Flouris

{"title":"Measuring the Impact of the Coronavirus Disease 2019 Pandemic on Mobility Aspirations and Behaviours","authors":"Davide J. Testa, Zaheer A. S. H. Nagarwala, J. Vale, Andres E. Carrillo, Cagney T. Sargent, Sharon Amollo, Mutono Nyamai, Belén Carballo-Leyenda, B. Onyima, Ibukun Afolabi, Tiago S. Mayor, Sally Hargreaves, Marija Marković, A. Flouris","doi":"10.3390/covid4020018","DOIUrl":"https://doi.org/10.3390/covid4020018","url":null,"abstract":"The coronavirus disease 2019 (COVID-19) pandemic prompted tens of thousands of people worldwide to migrate from cities in its early stages, leading to an increased spread of the virus. Understanding the factors driving relocation during a pandemic is crucial for effective outbreak control. We investigated how the pandemic influenced people’s aspirations and preparations to move, both domestically and internationally, surveying individuals in Greece, India, Italy, Kenya, Nigeria, Portugal, Serbia, Spain, and the United States of America. Out of 4448 eligible responses, 765 participants (17.2%) had a strong aspiration to move due to COVID-19, and 155 (3.5%) had already prepared. Those considering relocation were statistically significantly more likely to perceive moving to an area with fewer COVID-19 cases as protective against the virus (OR = 1.3, p < 0.05) or to know others who intended to relocate because of COVID-19 (OR = 1.5, p < 0.05). Conversely, a strong sense of being ‘at home’ reduced statistically significantly the strength of mobility aspirations (OR = 0.7, p < 0.01). Social alienation, social imitation, and the perceived efficacy of mobility increased aspirations to move due to COVID-19. This study emphasizes the rapid population movements at pandemic onset and their potential contribution to disease transmission, urging future pandemic planning to take account of such mobility dynamics.","PeriodicalId":72714,"journal":{"name":"COVID","volume":"52 10","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-02-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139777933","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Differential Diagnosis in the Management of Acute Respiratory Infections through Point-of-Care Rapid Testing in a Post-Pandemic Scenario in Latin America: Special Focus on COVID-19, Influenza, and Respiratory Syncytial Virus 在拉丁美洲大流行后通过护理点快速检测对急性呼吸道感染进行鉴别诊断：特别关注 COVID-19、流感和呼吸道合胞病毒

COVID Pub Date : 2024-02-10 DOI: 10.3390/covid4020017

C. Álvarez-Moreno, Evaldo Stanislau Affonso de Araújo, Elsa Baumeister, Katya A. Nogales Crespo, A. Kalergis, José Esteban Muñoz Medina, P. Tsukayama, C. Ugarte-Gil

{"title":"Differential Diagnosis in the Management of Acute Respiratory Infections through Point-of-Care Rapid Testing in a Post-Pandemic Scenario in Latin America: Special Focus on COVID-19, Influenza, and Respiratory Syncytial Virus","authors":"C. Álvarez-Moreno, Evaldo Stanislau Affonso de Araújo, Elsa Baumeister, Katya A. Nogales Crespo, A. Kalergis, José Esteban Muñoz Medina, P. Tsukayama, C. Ugarte-Gil","doi":"10.3390/covid4020017","DOIUrl":"https://doi.org/10.3390/covid4020017","url":null,"abstract":"This review provides a comprehensive summary of evidence to explore the role and value of differential diagnosis in the management of Acute Respiratory Infections (ARIs) through point-of-care (POC) rapid testing in a post-pandemic scenario, paying particular attention to coronavirus disease 2019 (COVID-19), influenza, and respiratory syncytial virus (RSV). The document builds on a review of literature and policies and a process of validation and feedback by a group of seven experts from Latin America (LATAM). Evidence was collected to understand scientific and policy perspectives on the differential diagnosis of ARIs and POC rapid testing, with a focus on seven countries: Argentina, Brazil, Chile, Colombia, Costa Rica, Mexico, and Peru. The evidence indicates that POC rapid testing can serve to improve ARI case management, epidemiological surveillance, research and innovation, and evidence-based decision-making. With multiple types of rapid tests available for POC, decisions regarding which tests to use require the consideration of the testing purpose, available resources, and test characteristics regarding accuracy, accessibility, affordability, and results turnaround time. Based on the understanding of the current situation, this document provides a set of recommendations for the implementation of POC rapid testing in LATAM, supporting decision-making and guiding efforts by a broad range of stakeholders.","PeriodicalId":72714,"journal":{"name":"COVID","volume":"19 3","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-02-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139846161","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Differential Diagnosis in the Management of Acute Respiratory Infections through Point-of-Care Rapid Testing in a Post-Pandemic Scenario in Latin America: Special Focus on COVID-19, Influenza, and Respiratory Syncytial Virus 在拉丁美洲大流行后通过护理点快速检测对急性呼吸道感染进行鉴别诊断：特别关注 COVID-19、流感和呼吸道合胞病毒

COVID Pub Date : 2024-02-10 DOI: 10.3390/covid4020017

C. Álvarez-Moreno, Evaldo Stanislau Affonso de Araújo, Elsa Baumeister, Katya A. Nogales Crespo, A. Kalergis, José Esteban Muñoz Medina, P. Tsukayama, C. Ugarte-Gil

{"title":"Differential Diagnosis in the Management of Acute Respiratory Infections through Point-of-Care Rapid Testing in a Post-Pandemic Scenario in Latin America: Special Focus on COVID-19, Influenza, and Respiratory Syncytial Virus","authors":"C. Álvarez-Moreno, Evaldo Stanislau Affonso de Araújo, Elsa Baumeister, Katya A. Nogales Crespo, A. Kalergis, José Esteban Muñoz Medina, P. Tsukayama, C. Ugarte-Gil","doi":"10.3390/covid4020017","DOIUrl":"https://doi.org/10.3390/covid4020017","url":null,"abstract":"This review provides a comprehensive summary of evidence to explore the role and value of differential diagnosis in the management of Acute Respiratory Infections (ARIs) through point-of-care (POC) rapid testing in a post-pandemic scenario, paying particular attention to coronavirus disease 2019 (COVID-19), influenza, and respiratory syncytial virus (RSV). The document builds on a review of literature and policies and a process of validation and feedback by a group of seven experts from Latin America (LATAM). Evidence was collected to understand scientific and policy perspectives on the differential diagnosis of ARIs and POC rapid testing, with a focus on seven countries: Argentina, Brazil, Chile, Colombia, Costa Rica, Mexico, and Peru. The evidence indicates that POC rapid testing can serve to improve ARI case management, epidemiological surveillance, research and innovation, and evidence-based decision-making. With multiple types of rapid tests available for POC, decisions regarding which tests to use require the consideration of the testing purpose, available resources, and test characteristics regarding accuracy, accessibility, affordability, and results turnaround time. Based on the understanding of the current situation, this document provides a set of recommendations for the implementation of POC rapid testing in LATAM, supporting decision-making and guiding efforts by a broad range of stakeholders.","PeriodicalId":72714,"journal":{"name":"COVID","volume":"117 22","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-02-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139786274","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Development of Mouse Hepatitis Virus Chimeric Reporter Viruses Expressing the 3CLpro Proteases of Human Coronaviruses HKU1 and OC43 Reveals Susceptibility to Inactivation by Natural Inhibitors Baicalin and Baicalein 表达人类冠状病毒 HKU1 和 OC43 的 3CLpro 蛋白酶的小鼠肝炎病毒嵌合报告病毒的开发揭示了天然抑制剂黄芩苷和黄芩素对灭活的敏感性

COVID Pub Date : 2024-02-09 DOI: 10.3390/covid4020016

Elise R Huffman, Jared X. Franges, Jayden M. Doster, Alexis R. Armstrong, Yara S Batista, Cameron M. Harrison, Jon D. Brooks, Morgan N. Thomas, Butler Student Virology Group, Sakshi Tomar, Christopher C. Stobart, Dia C. Beachboard

{"title":"Development of Mouse Hepatitis Virus Chimeric Reporter Viruses Expressing the 3CLpro Proteases of Human Coronaviruses HKU1 and OC43 Reveals Susceptibility to Inactivation by Natural Inhibitors Baicalin and Baicalein","authors":"Elise R Huffman, Jared X. Franges, Jayden M. Doster, Alexis R. Armstrong, Yara S Batista, Cameron M. Harrison, Jon D. Brooks, Morgan N. Thomas, Butler Student Virology Group, Sakshi Tomar, Christopher C. Stobart, Dia C. Beachboard","doi":"10.3390/covid4020016","DOIUrl":"https://doi.org/10.3390/covid4020016","url":null,"abstract":"The recent emergence of SARS-CoV-2 in 2019 has highlighted the necessity of antiviral therapeutics for current and future emerging coronaviruses. Recently, the traditional herbal medicines baicalein, baicalin, and andrographolide have shown inhibition against the main protease of SARS-CoV-2. This provides a promising new direction for COVID-19 therapeutics, but it remains unknown whether these three substances inhibit other human coronaviruses. In this study, we describe the development of novel chimeric mouse hepatitis virus (MHV) reporters that express firefly luciferase (FFL) and the 3CLpro proteases of human coronaviruses HKU1 and OC43. These chimeric viruses were used to determine if the phytochemicals baicalein, baicalin, and andrographolide are inhibitory against human coronavirus strains HKU1 and OC43. Our data show that both baicalein and baicalin exhibit inhibition towards the chimeric MHV strains. However, andrographolide induces cytotoxicity and failed to demonstrate selective toxicity towards the viruses. This study reports the development and use of a safe replicating reporter platform to investigate potential coronavirus 3CLpro inhibitors against common-cold human coronavirus strains HKU1 and OC43.","PeriodicalId":72714,"journal":{"name":"COVID","volume":" 14","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-02-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139789288","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Development of Mouse Hepatitis Virus Chimeric Reporter Viruses Expressing the 3CLpro Proteases of Human Coronaviruses HKU1 and OC43 Reveals Susceptibility to Inactivation by Natural Inhibitors Baicalin and Baicalein 表达人类冠状病毒 HKU1 和 OC43 的 3CLpro 蛋白酶的小鼠肝炎病毒嵌合报告病毒的开发揭示了天然抑制剂黄芩苷和黄芩素对灭活的敏感性

COVID Pub Date : 2024-02-09 DOI: 10.3390/covid4020016

Elise R Huffman, Jared X. Franges, Jayden M. Doster, Alexis R. Armstrong, Yara S Batista, Cameron M. Harrison, Jon D. Brooks, Morgan N. Thomas, Butler Student Virology Group, Sakshi Tomar, Christopher C. Stobart, Dia C. Beachboard

{"title":"Development of Mouse Hepatitis Virus Chimeric Reporter Viruses Expressing the 3CLpro Proteases of Human Coronaviruses HKU1 and OC43 Reveals Susceptibility to Inactivation by Natural Inhibitors Baicalin and Baicalein","authors":"Elise R Huffman, Jared X. Franges, Jayden M. Doster, Alexis R. Armstrong, Yara S Batista, Cameron M. Harrison, Jon D. Brooks, Morgan N. Thomas, Butler Student Virology Group, Sakshi Tomar, Christopher C. Stobart, Dia C. Beachboard","doi":"10.3390/covid4020016","DOIUrl":"https://doi.org/10.3390/covid4020016","url":null,"abstract":"The recent emergence of SARS-CoV-2 in 2019 has highlighted the necessity of antiviral therapeutics for current and future emerging coronaviruses. Recently, the traditional herbal medicines baicalein, baicalin, and andrographolide have shown inhibition against the main protease of SARS-CoV-2. This provides a promising new direction for COVID-19 therapeutics, but it remains unknown whether these three substances inhibit other human coronaviruses. In this study, we describe the development of novel chimeric mouse hepatitis virus (MHV) reporters that express firefly luciferase (FFL) and the 3CLpro proteases of human coronaviruses HKU1 and OC43. These chimeric viruses were used to determine if the phytochemicals baicalein, baicalin, and andrographolide are inhibitory against human coronavirus strains HKU1 and OC43. Our data show that both baicalein and baicalin exhibit inhibition towards the chimeric MHV strains. However, andrographolide induces cytotoxicity and failed to demonstrate selective toxicity towards the viruses. This study reports the development and use of a safe replicating reporter platform to investigate potential coronavirus 3CLpro inhibitors against common-cold human coronavirus strains HKU1 and OC43.","PeriodicalId":72714,"journal":{"name":"COVID","volume":"90 9-10","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-02-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139848982","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Patient-Perceived Impact of the COVID-19 Pandemic on Medication Adherence and Access to Care for Long-Term Diseases: A Cross-Sectional Online Survey 患者认为 COVID-19 大流行对坚持用药和获得长期疾病护理的影响：横断面在线调查

COVID Pub Date : 2024-02-08 DOI: 10.3390/covid4020015

Beatriz Santos, Younes Boulaguiem, H. Baysson, N. Pullen, I. Guessous, Stéphane Guerrier, S. Stringhini, Marie P. Schneider

{"title":"Patient-Perceived Impact of the COVID-19 Pandemic on Medication Adherence and Access to Care for Long-Term Diseases: A Cross-Sectional Online Survey","authors":"Beatriz Santos, Younes Boulaguiem, H. Baysson, N. Pullen, I. Guessous, Stéphane Guerrier, S. Stringhini, Marie P. Schneider","doi":"10.3390/covid4020015","DOIUrl":"https://doi.org/10.3390/covid4020015","url":null,"abstract":"The COVID-19 pandemic has been associated with lifestyle changes, reduced access to care and potential impacts on medication self-management. Our main objectives are to evaluate the impact of the pandemic on patient adherence and access to care and long-term medications and determine its association with sociodemographic and clinical factors. This study is part of the Specchio-COVID-19 longitudinal cohort study in Geneva, Switzerland, conducted through an online questionnaire. Among the 982 participants (median age: 56; 61% female), 827 took long-term medications. There were 76 reported changes in medication dosages, of which 24 (31%) were without a physician’s recommendation, and 51 delays in initiation or premature medication interruptions, of which 24 (47%) were without a physician’s recommendation. Only 1% (9/827) of participants faced medication access issues. Participants taking a respiratory medication had a four-times greater odds of reporting more regular medication (OR = 4.27; CI 95%: 2.11–8.63) intake, whereas each year increase in age was significantly associated with 6% fewer relative risks of discontinuation (OR = 0.94; CI 95%: 0.91–0.97) and 3% fewer relative risks of changes in medication dosage (OR = 0.97; CI 95%: 0.95–1.00). Despite the limited impact of the pandemic on adherence and access to medications, our results emphasize the need for understanding patient challenges when self-managing their long-term medication, notably during public health crises.","PeriodicalId":72714,"journal":{"name":"COVID","volume":" 31","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-02-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139791237","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Patient-Perceived Impact of the COVID-19 Pandemic on Medication Adherence and Access to Care for Long-Term Diseases: A Cross-Sectional Online Survey 患者认为 COVID-19 大流行对坚持用药和获得长期疾病护理的影响：横断面在线调查

COVID Pub Date : 2024-02-08 DOI: 10.3390/covid4020015

Beatriz Santos, Younes Boulaguiem, H. Baysson, N. Pullen, I. Guessous, Stéphane Guerrier, S. Stringhini, Marie P. Schneider

{"title":"Patient-Perceived Impact of the COVID-19 Pandemic on Medication Adherence and Access to Care for Long-Term Diseases: A Cross-Sectional Online Survey","authors":"Beatriz Santos, Younes Boulaguiem, H. Baysson, N. Pullen, I. Guessous, Stéphane Guerrier, S. Stringhini, Marie P. Schneider","doi":"10.3390/covid4020015","DOIUrl":"https://doi.org/10.3390/covid4020015","url":null,"abstract":"The COVID-19 pandemic has been associated with lifestyle changes, reduced access to care and potential impacts on medication self-management. Our main objectives are to evaluate the impact of the pandemic on patient adherence and access to care and long-term medications and determine its association with sociodemographic and clinical factors. This study is part of the Specchio-COVID-19 longitudinal cohort study in Geneva, Switzerland, conducted through an online questionnaire. Among the 982 participants (median age: 56; 61% female), 827 took long-term medications. There were 76 reported changes in medication dosages, of which 24 (31%) were without a physician’s recommendation, and 51 delays in initiation or premature medication interruptions, of which 24 (47%) were without a physician’s recommendation. Only 1% (9/827) of participants faced medication access issues. Participants taking a respiratory medication had a four-times greater odds of reporting more regular medication (OR = 4.27; CI 95%: 2.11–8.63) intake, whereas each year increase in age was significantly associated with 6% fewer relative risks of discontinuation (OR = 0.94; CI 95%: 0.91–0.97) and 3% fewer relative risks of changes in medication dosage (OR = 0.97; CI 95%: 0.95–1.00). Despite the limited impact of the pandemic on adherence and access to medications, our results emphasize the need for understanding patient challenges when self-managing their long-term medication, notably during public health crises.","PeriodicalId":72714,"journal":{"name":"COVID","volume":"84 4","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-02-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139851134","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The Effects of a Collegiate Recovery Community Psychotherapy Program Incorporating Equine Interaction during the COVID-19 Pandemic on Young Adults with Substance Abuse Disorder COVID-19 大流行期间融入马匹互动的高校康复社区心理治疗计划对药物滥用失调症青少年的影响

COVID Pub Date : 2024-01-25 DOI: 10.3390/covid4020013

K. Holtcamp, M. C. Nicodemus, Tommy Phillips, David Christiansen, B. Rude, Peter L. Ryan, K. Galarneau

{"title":"The Effects of a Collegiate Recovery Community Psychotherapy Program Incorporating Equine Interaction during the COVID-19 Pandemic on Young Adults with Substance Abuse Disorder","authors":"K. Holtcamp, M. C. Nicodemus, Tommy Phillips, David Christiansen, B. Rude, Peter L. Ryan, K. Galarneau","doi":"10.3390/covid4020013","DOIUrl":"https://doi.org/10.3390/covid4020013","url":null,"abstract":"While psychotherapy incorporating equine interaction (PIE) has proven to be a viable therapeutic intervention, it is not a common mental health service found on college campuses. Nevertheless, with the rise of mental health challenges on campuses after the COVID-19 pandemic, a need for effective therapeutic solutions is warranted. Therefore, the objective of this study was to determine the effect of a collegiate recovery community (CRC) PIE program for substance abuse disorder (SUD) compared to that of traditional cognitive behavioral therapy (CBT) and to determine whether physiological synchronization occurs between the human and horse during the therapy process. College-aged adults were recruited during the COVID-19 pandemic for two types of short-term SUD therapeutic interventions, CRC-PIE and CBT. Both groups completed a self-reporting survey assessing emotional safety. Vital signs measurements for human and horse participants within the CRC-PIE were collected prior to and after the first and last therapeutic sessions. Results concluded that although emotional safety did not improve significantly for PIE participants by the last therapy session (p = 0.85), emotional safety scores were significantly different between therapy types, with lower post-therapy scores for PIE (p = 0.04). As for physiological measures for PIE participants, respiratory rates (Human: p = 0.01; Horse: p = 0.01) and pain rating scores (Human: p = 0.03; Horse: p = 0.01) significantly decreased post-therapy and a strong positive correlation (R = 0.73, R2 = 0.53) associated with vital signs was observed between humans and horses. This human–horse physiological synchronization during the therapeutic intervention suggests that the horse may be a viable tool within campus CRC programs for the development of therapeutic alliances within the therapy process.","PeriodicalId":72714,"journal":{"name":"COVID","volume":"43 19","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-01-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139598151","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Addressing Inequality in the COVID-19 Pandemic in Africa: A Snapshot from Clinical Symptoms to Vaccine Distribution 解决非洲 COVID-19 大流行中的不平等问题：从临床症状到疫苗分发的缩影

COVID Pub Date : 2024-01-25 DOI: 10.3390/covid4020014

A. Pêgo, I. Lima, R. Gozzelino

{"title":"Addressing Inequality in the COVID-19 Pandemic in Africa: A Snapshot from Clinical Symptoms to Vaccine Distribution","authors":"A. Pêgo, I. Lima, R. Gozzelino","doi":"10.3390/covid4020014","DOIUrl":"https://doi.org/10.3390/covid4020014","url":null,"abstract":"On 30 January 2020, WHO declared COVID-19 a public health emergency of global concern. COVID-19 became pandemic on 11 March 2020, and spread unprecedently. No country was prepared to face its impact. Major fears started to be expressed for Africa, where dramatic consequences were expected, due to the weakness of health systems. In this review, we related major concerns, at that time but still present, regarding the limited resources in terms of qualified physicians and researchers, as well as the scarce funds to purchase essential medical equipment and improve hospital infrastructures. The difficulties to provide proper care became an undeniable mark of inequality, highlighting the need to empower local capacity and raise preparedness against infection outbreaks. The transmissibility of genetic variants affecting African nations, the immunopathology underlying comorbidities, sequelae, and pre-existing conditions, often related to changes in iron metabolism and enhancing COVID-19 severity, were described. The obstacles in adopting standardized prevention measures were highlighted, along with testing capacity biases and inequity of healthcare access and vaccine distribution. By providing a better understanding of the COVID-19 pandemic in Africa, we draw attention to the need for collaborative efforts to leverage the quality of healthcare and research in this continent.","PeriodicalId":72714,"journal":{"name":"COVID","volume":"39 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-01-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139598250","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

COVID最新文献