Clinical nutrition research最新文献

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The Association Between Dietary Acidity and Clinical Symptoms in Patients With Rheumatoid Arthritis. 类风湿性关节炎患者饮食酸度与临床症状的关系
Clinical nutrition research Pub Date : 2022-10-28 eCollection Date: 2022-10-01 DOI: 10.7762/cnr.2022.11.4.277
Arezoo Amjadi, Yahya Pasdar, Shahab Rezaeian, Mostafa Nachvak, Saeid Ghavamzadeh, Mohammad Alizadeh, Hadi Abdollahzad, Jafar Navabi
{"title":"The Association Between Dietary Acidity and Clinical Symptoms in Patients With Rheumatoid Arthritis.","authors":"Arezoo Amjadi,&nbsp;Yahya Pasdar,&nbsp;Shahab Rezaeian,&nbsp;Mostafa Nachvak,&nbsp;Saeid Ghavamzadeh,&nbsp;Mohammad Alizadeh,&nbsp;Hadi Abdollahzad,&nbsp;Jafar Navabi","doi":"10.7762/cnr.2022.11.4.277","DOIUrl":"https://doi.org/10.7762/cnr.2022.11.4.277","url":null,"abstract":"<p><p>This study aimed to investigate the relationship between dietary acidity load and clinical symptoms in the patients with rheumatoid arthritis (RA). This case-control study examined 55 patients with RA and 215 healthy individuals in a Ravansar non-communicable diseases (RaNCDs) cohort study, Iran. Participants' food intakes were assessed using a validated food frequency questionnaire. The dietary acidity was calculated using potential renal acid load (PRAL), net endogenous acid production (NEAP), and dietary acid load (DAL) scores. The patients with RA were identified based on the self-reporting, medications history, and the approval of the cohort center physician following patients' examination. The odds ratio (OR) of joint stiffness in fully adjusted model was greater in the upper median of dietary acidity than in the lower median (PRAL: odds ratio [OR], 1.18; 95% confidence interval [CI], 0.59-2.36), but there was no statistically significant difference. The OR of joint pain in the upper median of dietary acidity was less than in the lower median in fully adjusted model (PRAL: OR, 0.70; 95% CI, 0.46-1.29), but the difference was not statistically significant. After adjusting potential confounders, people in the upper median of dietary acidity had a higher OR of developing RA than those in the lower median (PRAL: OR, 1.39; 95% CI, 0.70-2.76); however, it was not statistically significant. There was not any statistically significant relationship among dietary acidity and the odds of joint pain, joint stiffness, and developing RA.</p>","PeriodicalId":72617,"journal":{"name":"Clinical nutrition research","volume":"11 4","pages":"277-288"},"PeriodicalIF":0.0,"publicationDate":"2022-10-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/70/f3/cnr-11-277.PMC9633968.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40704737","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Use of Complementary and Alternative Medicine (CAM) in Patients With Colorectal Cancer. 大肠癌患者使用补充和替代医学 (CAM)。
Clinical nutrition research Pub Date : 2022-10-27 eCollection Date: 2022-10-01 DOI: 10.7762/cnr.2022.11.4.255
Jeongwon Yeom, Jung Mi Lee
{"title":"Use of Complementary and Alternative Medicine (CAM) in Patients With Colorectal Cancer.","authors":"Jeongwon Yeom, Jung Mi Lee","doi":"10.7762/cnr.2022.11.4.255","DOIUrl":"10.7762/cnr.2022.11.4.255","url":null,"abstract":"<p><p>This study was conducted to analyze the relationship between cancer-related stress and the types of complementary and alternative medicine (CAM) used by subjects diagnosed with colorectal cancer. The number of study subjects was 142, and for data analysis, descriptive statistics, t-test, χ<sup>2</sup> test, logistic regression procedures were performed. Of the subjects, 114 were CAM users, who accounted for 79.6%. When it came to using CAM, 82 (72.6%) said they did \"to prevent cancer recurrence.\" The most popular reason for not using CAM was \"to focus on treatment as instructed by the doctor,\" with 22 (75.8%) respondents selecting the answer. Of those who used CAM, 79 (55.6%) said they took \"dietary supplements,\" followed by 65 (45.8%) who picked \"vitamins and minerals.\" Regarding CAM usage, ginger, aloe, swimming, and walking had the highest satisfaction (4.25 ± 0.71). The cancer-related stress of subjects who use CAM (18.21 ± 15.37) was higher than that of subjects who did not use CAM (10.11 ± 12.08). Logistic regression analysis determined that cancer-related stress were factors significantly associated with CAM use. Patients using CAM had higher cancer-related stress, suggesting that stress on cancer increased CAM interest. Safe and reliable CAM information and standardized recommendations should be provided to cancer survivors. We propose the development of training programs for CAM to improve communication between medical staff and patients and to protect patients.</p>","PeriodicalId":72617,"journal":{"name":"Clinical nutrition research","volume":"11 4","pages":"255-263"},"PeriodicalIF":0.0,"publicationDate":"2022-10-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/fa/db/cnr-11-255.PMC9633969.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40687680","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Iron Homeostasis and Energy Metabolism in Obesity. 肥胖中的铁稳态和能量代谢。
Clinical nutrition research Pub Date : 2022-10-27 eCollection Date: 2022-10-01 DOI: 10.7762/cnr.2022.11.4.316
Se Lin Kim, Sunhye Shin, Soo Jin Yang
{"title":"Iron Homeostasis and Energy Metabolism in Obesity.","authors":"Se Lin Kim,&nbsp;Sunhye Shin,&nbsp;Soo Jin Yang","doi":"10.7762/cnr.2022.11.4.316","DOIUrl":"https://doi.org/10.7762/cnr.2022.11.4.316","url":null,"abstract":"<p><p>Iron plays a role in energy metabolism as a component of vital enzymes and electron transport chains (ETCs) for adenosine triphosphate (ATP) synthesis. The tricarboxylic acid (TCA) cycle and oxidative phosphorylation are crucial in generating ATP in mitochondria. At the mitochondria matrix, heme and iron-sulfur clusters are synthesized. Iron-sulfur cluster is a part of the aconitase in the TCA cycle and a functional or structural component of electron transfer proteins. Heme is the prosthetic group for cytochrome c, a principal component of the respiratory ETC. Regarding fat metabolism, iron regulates mitochondrial fat oxidation and affects the thermogenesis of brown adipose tissue (BAT). Thermogenesis is a process that increases energy expenditure, and BAT is a tissue that generates heat via mitochondrial fuel oxidation. Iron deficiency may impair mitochondrial fuel oxidation by inhibiting iron-containing molecules, leading to decreased energy expenditure. Although it is expected that impaired mitochondrial fuel oxidation may be restored by iron supplementation, its underlying mechanisms have not been clearly identified. Therefore, this review summarizes the current evidence on how iron regulates energy metabolism considering the TCA cycle, oxidative phosphorylation, and thermogenesis. Additionally, we relate iron-mediated metabolic regulation to obesity and obesity-related complications.</p>","PeriodicalId":72617,"journal":{"name":"Clinical nutrition research","volume":"11 4","pages":"316-330"},"PeriodicalIF":0.0,"publicationDate":"2022-10-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/a8/36/cnr-11-316.PMC9633967.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40687682","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 3
Self-care Through Dynamic Appetite Alteration: A Grounded Theory Study of Patient Experience on Maintenance Hemodialysis. 通过动态食欲改变的自我护理:维持性血液透析患者体验的扎根理论研究。
Clinical nutrition research Pub Date : 2022-10-26 eCollection Date: 2022-10-01 DOI: 10.7762/cnr.2022.11.4.264
Wonsun Hwang, Ji-Hyun Lee, Juha Nam, Jieun Oh, Inwhee Park, Mi Sook Cho
{"title":"Self-care Through Dynamic Appetite Alteration: A Grounded Theory Study of Patient Experience on Maintenance Hemodialysis.","authors":"Wonsun Hwang,&nbsp;Ji-Hyun Lee,&nbsp;Juha Nam,&nbsp;Jieun Oh,&nbsp;Inwhee Park,&nbsp;Mi Sook Cho","doi":"10.7762/cnr.2022.11.4.264","DOIUrl":"https://doi.org/10.7762/cnr.2022.11.4.264","url":null,"abstract":"<p><p>Hemodialysis (HD) patients can experience appetite alterations that affect meals and nutritional status. Few qualitative studies have assessed the chronic impact of HD on the everyday diet. This study aimed to characterise comprehensively the experiences of HD patients adapting to appetite alteration. Semi-structured, face-to-face interviews were conducted in a unit of a tertiary hospital to understand patient experiences with appetite alteration. An interview guide was used to consider adaptive processes developed after reviewing the literature and based on the researchers' clinical experiences. A single researcher conducted all interviews to maintain consistency in data collection. The interview content was analysed using Nvivo 11 based on grounded theory and constant comparison analysis. As a results, the mean age and HD vintage of 14 participants were 60 and 5.8 years, respectively. We developed a self-care model based on HD patient experiences with appetite alteration based on axial and selective coding. Differences in urea sensitivity, taste alteration, and social support could be explained by timing of transitions, life events, and responses to stress. Self-care processes are adapted through the processes of \"self-registration\" and \"self-reconstruction,\" starting with \"disruption.\" At the stage of adjustment, 4 self-management types were derived based on pattern of self-care: self-initiator, follower, realist, and pessimist. The results of this study provide unique qualitative insight into the lived experiences of HD patients experiencing appetite alteration and their self-care processes. By recognising dietary challenges, health teams can better support HD patients in the transition from dietary education to self-care.</p>","PeriodicalId":72617,"journal":{"name":"Clinical nutrition research","volume":"11 4","pages":"264-276"},"PeriodicalIF":0.0,"publicationDate":"2022-10-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/65/ba/cnr-11-264.PMC9633972.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40687683","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Obesity, Diabetes Mellitus, and Metabolic Syndrome: Review in the Era of COVID-19. 肥胖、糖尿病和代谢综合征:在COVID-19时代的回顾
Clinical nutrition research Pub Date : 2022-10-24 eCollection Date: 2022-10-01 DOI: 10.7762/cnr.2022.11.4.331
Behnaz Abiri, Amirhossein Ramezani Ahmadi, Mahdi Hejazi, Shirin Amini
{"title":"Obesity, Diabetes Mellitus, and Metabolic Syndrome: Review in the Era of COVID-19.","authors":"Behnaz Abiri,&nbsp;Amirhossein Ramezani Ahmadi,&nbsp;Mahdi Hejazi,&nbsp;Shirin Amini","doi":"10.7762/cnr.2022.11.4.331","DOIUrl":"https://doi.org/10.7762/cnr.2022.11.4.331","url":null,"abstract":"<p><p>Coronavirus disease 2019 (COVID-19), a novel coronavirus named severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is now at pandemic levels leading to considerable morbidity and mortality throughout the globe. Patients with obesity, diabetes, and metabolic syndrome (MetS) are mainly susceptible and more probably to get severe side effects when affected by this virus. The pathophysiologic mechanisms for these notions have not been completely known. The pro-inflammatory milieu observed in patients with metabolic disruption could lead to COVID-19-mediated host immune dysregulation, such as immune dysfunction, severe inflammation, microvascular dysfunction, and thrombosis. The present review expresses the current knowledge regarding the influence of obesity, diabetes mellitus, and MetS on COVID-19 infection and severity, and their pathophysiological mechanisms.</p>","PeriodicalId":72617,"journal":{"name":"Clinical nutrition research","volume":"11 4","pages":"331-346"},"PeriodicalIF":0.0,"publicationDate":"2022-10-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/00/e8/cnr-11-331.PMC9633974.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40687681","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 4
The Effects of Capsinoids and Fermented Red Pepper Paste Supplementation on Lipid Profile: A Systematic Review and Meta-Analysis of Randomized Controlled Trials. 补充辣椒素和发酵红辣椒酱对血脂的影响:随机对照试验的系统评价和荟萃分析。
Clinical nutrition research Pub Date : 2022-10-24 eCollection Date: 2022-10-01 DOI: 10.7762/cnr.2022.11.4.302
Mohammad Reza Amini, Nastaran Payandeh, Fatemeh Sheikhhossein, Mohsen Alvani, Alireza Talebyan, Fatemeh Mohtashaminia, Azita Hekmatdoost
{"title":"The Effects of Capsinoids and Fermented Red Pepper Paste Supplementation on Lipid Profile: A Systematic Review and Meta-Analysis of Randomized Controlled Trials.","authors":"Mohammad Reza Amini,&nbsp;Nastaran Payandeh,&nbsp;Fatemeh Sheikhhossein,&nbsp;Mohsen Alvani,&nbsp;Alireza Talebyan,&nbsp;Fatemeh Mohtashaminia,&nbsp;Azita Hekmatdoost","doi":"10.7762/cnr.2022.11.4.302","DOIUrl":"https://doi.org/10.7762/cnr.2022.11.4.302","url":null,"abstract":"<p><p>The present systematic review and meta-analysis were conducted in order to investigate the effects of capsinoids and fermented red pepper paste (FRPP) supplementation on lipid profile. Relevant studies were identified by searches of five databases from inception to November 2021 using relevant keywords. All clinical trials investigating the effect of capsinoids and FRPP on total cholesterol (TC), triglycerides (TG), high-density lipoprotein cholesterol (HDL-C), and low-density lipoprotein cholesterol (LDL-C) were included. Out of 1,203 citations, eight trials that enrolled 393 participants were included. Capsinoids and FRPP resulted in a significant reduction in TC (weighted mean differences [WMD], -9.92 mg/dL; 95% confidence interval [CI], -17.92 to -1.92; p = 0.015) but no significant changes in TG (WMD, -19.38 mg/dL; 95% CI, -39.94 to 1.18; p = 0.065), HDL-C (WMD, 0.83 mg/dL; 95% CI, -0.76 to 2.42; p = 0.305) and LDL-C (WMD, -0.59 mg/dL; 95% CI, -4.96 to 3.79; p = 0.793). Greater effects on TC were detected in trials performed on duration lasting less than twelve weeks, mean age of > 40, both sexes, and sample size of > 50. TG was reduced by using FRPP in studies conducted on mean age of > 40. HDL-C increased by using FRPP in studies conducted on duration of < 12 weeks, mean age of > 40, and sample size of ≤ 50. Overall, these data provided evidence that capsinoids and FRPP supplementation has beneficial effects on TC but not TG, HDL-C, and LDL-C.</p>","PeriodicalId":72617,"journal":{"name":"Clinical nutrition research","volume":"11 4","pages":"302-315"},"PeriodicalIF":0.0,"publicationDate":"2022-10-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/69/f1/cnr-11-302.PMC9633970.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40704735","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 8
The Association Between Dietary Diversity Score and Cardiovascular Risk Factors Among Patients With Pemphigus Vulgaris: A Cross Sectional Study. 寻常型天疱疮患者饮食多样性评分与心血管危险因素的相关性:一项横断面研究
Clinical nutrition research Pub Date : 2022-10-24 eCollection Date: 2022-10-01 DOI: 10.7762/cnr.2022.11.4.289
Atefeh Seifollahi, Mahboubeh Rezaei Fazl, Leila Setayesh, Mohammad Hassan Javanbakht, Maryam Daneshpazhooh, Sakineh Shab-Bidar, Mehdi Yaseri
{"title":"The Association Between Dietary Diversity Score and Cardiovascular Risk Factors Among Patients With Pemphigus Vulgaris: A Cross Sectional Study.","authors":"Atefeh Seifollahi,&nbsp;Mahboubeh Rezaei Fazl,&nbsp;Leila Setayesh,&nbsp;Mohammad Hassan Javanbakht,&nbsp;Maryam Daneshpazhooh,&nbsp;Sakineh Shab-Bidar,&nbsp;Mehdi Yaseri","doi":"10.7762/cnr.2022.11.4.289","DOIUrl":"https://doi.org/10.7762/cnr.2022.11.4.289","url":null,"abstract":"<p><p>This study was conducted to evaluate the associations between dietary diversity score (DDS) and cardiovascular risk factors in this population. In this cross-sectional study, 187 patients, aged 18-65 years with pemphigus vulgaris were included. DDS was assessed by a 24-hour dietary recall method. Anthropometric measures and biochemical parameters assessed according to standard protocols. Multivariate linear regression analyses used for detecting any associations between DDS and cardiovascular risk factors. The mean ± standard deviation age and body mass index of studied participants were (46.71 ± 11.49 years) and (27.83 ± 4.39 kg/m<sup>2</sup>) respectively. Our findings showed that a higher DDS intake was related with higher consumption of vegetables (p = 0.001), dairy products (p < 0.001), cereals (p = 0.002), red and processed meat (p < 0.001), sweets and desserts (p < 0.001). After controlling for confounding variables, the results showed positive associations between DDS and high-density lipoprotein cholesterol (HDL-C, β = 1.87, 95% confidence interval [CI], 0.30-3.45, p = 0.02) and total cholesterol (TC) levels (β = 6.41, 95% CI, 1.62-11.03, p = 0.02) (β = 1.75, 95% CI, 0.20-3.30, p = 0.02). However, there were no associations between DDS and prevalence of obesity and glucose homeostasis. The results of this cross-sectional study showed that DDS might be associated with increased HDL-C and TC. However, further prospective studies are needed to prove these findings.</p>","PeriodicalId":72617,"journal":{"name":"Clinical nutrition research","volume":"11 4","pages":"289-301"},"PeriodicalIF":0.0,"publicationDate":"2022-10-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/58/21/cnr-11-289.PMC9633973.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40687679","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Pre-treatment Nutritional Risk Assessment by NRS-2002 Predicts Prognosis in Patients With Advanced Biliary Tract Cancer: A Single Center Retrospective Study. NRS-2002治疗前营养风险评估预测晚期胆道癌患者预后:一项单中心回顾性研究
Clinical nutrition research Pub Date : 2022-07-28 eCollection Date: 2022-07-01 DOI: 10.7762/cnr.2022.11.3.183
Se Eung Oh, Juong Soon Park, Hei-Cheul Jeung
{"title":"Pre-treatment Nutritional Risk Assessment by NRS-2002 Predicts Prognosis in Patients With Advanced Biliary Tract Cancer: A Single Center Retrospective Study.","authors":"Se Eung Oh,&nbsp;Juong Soon Park,&nbsp;Hei-Cheul Jeung","doi":"10.7762/cnr.2022.11.3.183","DOIUrl":"https://doi.org/10.7762/cnr.2022.11.3.183","url":null,"abstract":"<p><p>We investigated the predictors of survival in patients with advanced BTC according to their baseline nutritional status estimated by the Nutritional Risk Screening (NRS)-2002. From September 2006 to July 2017, we reviewed the data of 601 inpatients with BTC. Data on demographic and clinical parameters was collected from electronic medical records, and overall survival (OS) and progression-free survival were analyzed using the Kaplan-Meier method and the stepwise Cox regression analysis. Patients with an NRS-2002 score of ≤ 2, 3, and ≥ 4 were respectively classified as \"no risk,\" \"moderate risk,\" \"high risk.\" Following initial NRS-2002 score, 333 patients (55%) were classified as \"no-risk,\" 109 patients (18%) as \"moderate-risk,\" and 159 patients (27%) as \"high-risk.\" Survival analysis demonstrated significant differences in the median OS: \"no-risk\": 12.6 months (95% confidence interval [CI], 11.5-13.7); \"moderate-risk\": 6.1 months (95% CI, 4.3-8.0); and \"high-risk\": 3.9 months (95% CI, 3.2-4.6) (p < 0.001). NRS-2002 score was an independent factor for OS (hazard ratio [HR], 1.616 for \"moderate-risk\", 95% CI, 1.288-2.027, p < 0.001; HR, 2.121 for \"high-risk\", 95% CI, 1.722-2.612, p < 0.001), along with liver metastasis, peritoneal seeding, white blood cell count, platelet count, neutrophil-to-lymphocyte ratio, cholesterol, carcinoembryonic antigen, and carbohydrate antigen 19-9. In conclusion, baseline NRS-2002 is an appropriate method for discriminating those who are already malnourished and who have poor prognosis in advanced BTC patient. Significance of these results merit further validation to be integrated in the routine practice to improve quality of care in BTC patients.</p>","PeriodicalId":72617,"journal":{"name":"Clinical nutrition research","volume":"11 3","pages":"183-193"},"PeriodicalIF":0.0,"publicationDate":"2022-07-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/b9/e7/cnr-11-183.PMC9348911.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40616573","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 2
Anti-hypertensive Effects of Artichoke Supplementation in Adults: A Systematic Review and Dose-response Meta-analysis of Randomized Controlled Trials. 成人补充洋蓟的降压作用:随机对照试验的系统评价和剂量反应荟萃分析。
Clinical nutrition research Pub Date : 2022-07-26 eCollection Date: 2022-07-01 DOI: 10.7762/cnr.2022.11.3.214
Mohammad Reza Amini, Fatemeh Sheikhhossein, Mohsen Alvani, Seyyed Morteza Seyyed Shoura, Asma Sohrabnavi, Ehsan Heidarian, Azita Hekmatdoost
{"title":"Anti-hypertensive Effects of Artichoke Supplementation in Adults: A Systematic Review and Dose-response Meta-analysis of Randomized Controlled Trials.","authors":"Mohammad Reza Amini,&nbsp;Fatemeh Sheikhhossein,&nbsp;Mohsen Alvani,&nbsp;Seyyed Morteza Seyyed Shoura,&nbsp;Asma Sohrabnavi,&nbsp;Ehsan Heidarian,&nbsp;Azita Hekmatdoost","doi":"10.7762/cnr.2022.11.3.214","DOIUrl":"https://doi.org/10.7762/cnr.2022.11.3.214","url":null,"abstract":"<p><p>Despite controversies, no earlier study has systematically summarized findings from earlier studies on the effect of artichoke supplementation on blood pressure. Therefore, current systematic review and meta-analysis was done on the effect of artichoke supplementation on systolic blood pressure (SBP) and diastolic blood pressure (DBP) in adults. Five databases were searched from inception to January 2022 using relevant keywords. All randomized clinical trials investigating the impact of oral artichoke supplementation on any of the blood pressure parameters including SBP or/and DBP were included. Out of 1,507 citations, 7 trials that enrolled 472 subjects were included. Artichoke supplementation resulted in significant reduction in SBP (weighted mean difference [WMD], -2.01 mmHg; 95% confidence interval [CI], -3.78, -0.24; p = 0.026) and DBP (WMD, -1.45 mmHg; 95% CI, -2.81, -0.08; p = 0.038). Greater effects on SBP were detected in trials using ≤ 500 mg artichoke, lasted > 8 weeks, participants aged < 50 years' old and sample size ≤ 70. There was also a similar impact of artichoke on DBP. However, significant non-linear associations were found between artichoke supplementation dosage and study duration with both SBP (for dosage: p<sub>non-linearity</sub> = 0.002, for duration: p<sub>non-linearity</sub> = 0.016) and DBP (for dosage: p<sub>non-linearity</sub> = 0.005, for duration: p<sub>non-linearity</sub> = 0.003). We found a significant reduction in both SBP and DBP following artichoke supplementation in adults. It could be proposed as a hypotensive supplement in hypertension management.</p>","PeriodicalId":72617,"journal":{"name":"Clinical nutrition research","volume":"11 3","pages":"214-227"},"PeriodicalIF":0.0,"publicationDate":"2022-07-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/13/5c/cnr-11-214.PMC9348915.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40616574","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Nutritional Intervention for a Critically Ill Trauma Patient: A Case Report. 创伤重症患者的营养干预1例。
Clinical nutrition research Pub Date : 2022-07-25 eCollection Date: 2022-07-01 DOI: 10.7762/cnr.2022.11.3.153
Seong Hyeon Kim, Sun Jung Kim, Woojeong Kim
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