Clinical nutrition research最新文献_第7页

Bitter Taste Receptor TAS2R38 Genetic Variation (rs10246939), Dietary Nutrient Intake, and Bio-Clinical Parameters in Koreans. 韩国人苦味受体TAS2R38遗传变异(rs10246939)、膳食营养摄入和生物临床参数

Clinical nutrition research Pub Date : 2023-01-01 DOI: 10.7762/cnr.2023.12.1.40

Benish, Jeong-Hwa Choi

{"title":"Bitter Taste Receptor TAS2R38 Genetic Variation (rs10246939), Dietary Nutrient Intake, and Bio-Clinical Parameters in Koreans.","authors":"Benish, Jeong-Hwa Choi","doi":"10.7762/cnr.2023.12.1.40","DOIUrl":"https://doi.org/10.7762/cnr.2023.12.1.40","url":null,"abstract":"Differential bitterness perception associated with genetic polymorphism in the bitter taste receptor gene taste 2 receptor member 38 (TAS2R38) may influence an individual's food preferences, nutrition consumption, and eventually chronic nutrition-related disorders including cardiovascular disease. Therefore, the effect of genetic variations on nutritional intake and clinical markers needs to be elaborated for health and disease prevention. In this study, we conducted sex-stratified analysis to examine the association between genetic variant TAS2R38 rs10246939 A > G with daily nutritional intake, blood pressure, and lipid parameters in Korean adults (males = 1,311 and females = 2,191). We used the data from the Multi Rural Communities Cohort, Korean Genome and Epidemiology Study. Findings suggested that the genetic variant TAS2R38 rs10246939 was associated with dietary intake of micronutrients including calcium (adjusted p = 0.007), phosphorous (adjusted p = 0.016), potassium (adjusted p = 0.022), vitamin C (adjusted p = 0.009), and vitamin E (adjusted p = 0.005) in females. However, this genetic variant did not influence blood glucose, lipid profile parameters, and other blood pressure markers. These may suggest that this genetic variation is associated with nutritional intake, but its clinical effect was not found. More studies are needed to explore whether TAS2R38 genotype may be a potential predictive marker for the risk of metabolic diseases via modulation of dietary intake.","PeriodicalId":72617,"journal":{"name":"Clinical nutrition research","volume":"12 1","pages":"40-53"},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/0a/21/cnr-12-40.PMC9900072.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10735569","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The Impact of Obesity Surgery on Serum Uric Acid in People With Severe Obesity: A Retrospective Study. 肥胖手术对严重肥胖患者血清尿酸的影响:一项回顾性研究

Clinical nutrition research Pub Date : 2023-01-01 DOI: 10.7762/cnr.2023.12.1.21

Leila Vafa, Masoud Amini, Hooman Kamran, Ladan Aghakhani, Seyed Vahid Hosseini, Zahra Mohammadi, Neda Haghighat

{"title":"The Impact of Obesity Surgery on Serum Uric Acid in People With Severe Obesity: A Retrospective Study.","authors":"Leila Vafa, Masoud Amini, Hooman Kamran, Ladan Aghakhani, Seyed Vahid Hosseini, Zahra Mohammadi, Neda Haghighat","doi":"10.7762/cnr.2023.12.1.21","DOIUrl":"https://doi.org/10.7762/cnr.2023.12.1.21","url":null,"abstract":"Studies indicate an association between hyperuricemia (HUA) and metabolic syndrome risk factors. On the other hand, obesity is a major modifiable and independent risk factor for HUA and gout. However, evidence concerning the effects of bariatric surgery on serum uric acid levels is limited and not completely clarified. This retrospective study was carried out with 41 patients who underwent sleeve gastrectomy (n = 26) and Roux-en-Y gastric bypass (n = 15) from September 2019 to October 2021. Anthropometric, clinical, and biochemical data, including uric acid blood urea nitrogen and creatinine fasting blood sugar (FBS), serum triglyceride (TG), and serum cholesterol, high-density lipoprotein (HDL), low-density lipoprotein (LDL), were measured preoperatively and postoperative 3, 6 and 12 months. From baseline to 6 and 12 months, bariatric surgery resulted in a significant decrease in serum uric acid of patients with severe obesity (p < 0.001). The decreases in serum FBS, TG, and cholesterol of patients were significant during 6 and 12 months of follow-up (p < 0.05). However, the HDL increase of patients was not statistically significant in 6 and 12 months (p > 0.05). Besides, although patients' serum level of LDL decreased significantly during the 6 months of follow-up (p = 0.007), it was not significant after 12 months (p = 0.092). Bariatric surgery significantly reduces serum uric acid levels. Therefore, it may be an effective supplementary therapy for lowering serum uric acid concentrations in morbidly obese patients.","PeriodicalId":72617,"journal":{"name":"Clinical nutrition research","volume":"12 1","pages":"21-28"},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/55/04/cnr-12-21.PMC9900075.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10744628","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Effect of Tart Cherry Juice Consumption on Body Composition and Anthropometric Measures: A Systematic Review and Meta-Analysis of Randomized Controlled Trials. 饮用酸樱桃汁对身体成分和人体测量的影响:随机对照试验的系统回顾和荟萃分析。

Clinical nutrition research Pub Date : 2023-01-01 DOI: 10.7762/cnr.2023.12.1.65

Mohammad Reza Amini, Nastaran Payandeh, Fatemeh Sheikhhossein, Hossein Shahinfar, Sanaz Pourreza, Azita Hekmatdoost

{"title":"Effect of Tart Cherry Juice Consumption on Body Composition and Anthropometric Measures: A Systematic Review and Meta-Analysis of Randomized Controlled Trials.","authors":"Mohammad Reza Amini, Nastaran Payandeh, Fatemeh Sheikhhossein, Hossein Shahinfar, Sanaz Pourreza, Azita Hekmatdoost","doi":"10.7762/cnr.2023.12.1.65","DOIUrl":"https://doi.org/10.7762/cnr.2023.12.1.65","url":null,"abstract":"The present systematic review and meta-analysis were accomplished to understand the effects of tart cherry juice consumption on body composition and anthropometric measures. Five databases were searched using relevant keywords from inception to January 2022. All clinical trials investigating the effect of tart cherry juice consumption on body weight (BW), body mass index (BMI), waist circumference (WC), fat mass (FM), fat-free mass (FFM), and percentage body fat (PBF) were included. Out of 441 citations, 6 trials that enrolled 126 subjects were included. Tart cherry juice consumption significantly did not reduce BW (weighted mean difference [WMD], -0.4 kg; 95% confidence interval [CI], -3.25 to 2.46; p = 0.789; GRADE = low), BMI (WMD, -0.07 kg/m2; 95% CI, -0.89 to 0.74; p = 0.857; GRADE = low), FM (WMD, 0.21 kg; 95% CI, -1.83 to 2.25; p = 0.837; GRADE = low), FFM (WMD, -0.12 kg; 95% CI, -2.47 to 2.27; p = 0.919; GRADE = low), WC (WMD, 1.69 cm; 95% CI, -1.88 to 5.27; p = 0.353; GRADE = low), and PBF (WMD, 0.18%; 95% CI, -1.81 to -2.17; p = 0.858; GRADE = low). Overall, these data suggest that tart cherry juice consumption has no significant effect on BW, BMI, FM, FFM, WC, and PBF.","PeriodicalId":72617,"journal":{"name":"Clinical nutrition research","volume":"12 1","pages":"65-76"},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/7e/4c/cnr-12-65.PMC9900077.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10735571","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The Effect of Green Coffee Supplementation on Lipid Profile, Glycemic Indices, Inflammatory Biomarkers and Anthropometric Indices in Iranian Women With Polycystic Ovary Syndrome: A Randomized Clinical Trial. 补充绿咖啡对伊朗多囊卵巢综合征妇女血脂、血糖指数、炎症生物标志物和人体测量指标的影响:一项随机临床试验

Clinical nutrition research Pub Date : 2022-10-28 eCollection Date: 2022-10-01 DOI: 10.7762/cnr.2022.11.4.241

Mehrnoush Meshkani, Ahmad Saedisomeolia, Mirsaeed Yekaninejad, Seyed Ahmad Mousavi, Azam Ildarabadi, Marzieh Vahid-Dastjerdi

{"title":"The Effect of Green Coffee Supplementation on Lipid Profile, Glycemic Indices, Inflammatory Biomarkers and Anthropometric Indices in Iranian Women With Polycystic Ovary Syndrome: A Randomized Clinical Trial.","authors":"Mehrnoush Meshkani, Ahmad Saedisomeolia, Mirsaeed Yekaninejad, Seyed Ahmad Mousavi, Azam Ildarabadi, Marzieh Vahid-Dastjerdi","doi":"10.7762/cnr.2022.11.4.241","DOIUrl":"https://doi.org/10.7762/cnr.2022.11.4.241","url":null,"abstract":"Polycystic ovary syndrome (PCOS) is a heterogeneous clinical syndrome. Recent studies examine different strategies to modulate its related complications. Chlorogenic acid, as a bioactive component of green coffee (GC), is known to have great health benefits. The present study aimed to determine the effect of GC on lipid profile, glycemic indices, and inflammatory biomarkers. Forty-four PCOS patients were enrolled in this randomized clinical trial of whom 34 have completed the study protocol. The intervention group (n = 17) received 400 mg of GC supplements, while the placebo group (n = 17) received the same amount of starch for six weeks. Then, glycemic indices, lipid profiles, and inflammatory parameters were measured. After the intervention period, no significant difference was shown in fasting blood sugar, insulin level, Homeostasis model assessment of insulin resistance index, low-density lipoprotein, high-density lipoprotein, Interleukin 6 or 10 between supplementation and placebo groups. However, cholesterol and triglyceride serum levels decreased significantly in the intervention group (p < 0.05). This research confirmed that GC supplements might improve some lipid profiles in women with PCOS. However, more detailed studies with larger sample sizes are required to prove the effectiveness of this supplement.","PeriodicalId":72617,"journal":{"name":"Clinical nutrition research","volume":"11 4","pages":"241-254"},"PeriodicalIF":0.0,"publicationDate":"2022-10-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/c4/5a/cnr-11-241.PMC9633971.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40687684","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 2

The Association Between Dietary Acidity and Clinical Symptoms in Patients With Rheumatoid Arthritis. 类风湿性关节炎患者饮食酸度与临床症状的关系

Clinical nutrition research Pub Date : 2022-10-28 eCollection Date: 2022-10-01 DOI: 10.7762/cnr.2022.11.4.277

Arezoo Amjadi, Yahya Pasdar, Shahab Rezaeian, Mostafa Nachvak, Saeid Ghavamzadeh, Mohammad Alizadeh, Hadi Abdollahzad, Jafar Navabi

{"title":"The Association Between Dietary Acidity and Clinical Symptoms in Patients With Rheumatoid Arthritis.","authors":"Arezoo Amjadi, Yahya Pasdar, Shahab Rezaeian, Mostafa Nachvak, Saeid Ghavamzadeh, Mohammad Alizadeh, Hadi Abdollahzad, Jafar Navabi","doi":"10.7762/cnr.2022.11.4.277","DOIUrl":"https://doi.org/10.7762/cnr.2022.11.4.277","url":null,"abstract":"This study aimed to investigate the relationship between dietary acidity load and clinical symptoms in the patients with rheumatoid arthritis (RA). This case-control study examined 55 patients with RA and 215 healthy individuals in a Ravansar non-communicable diseases (RaNCDs) cohort study, Iran. Participants' food intakes were assessed using a validated food frequency questionnaire. The dietary acidity was calculated using potential renal acid load (PRAL), net endogenous acid production (NEAP), and dietary acid load (DAL) scores. The patients with RA were identified based on the self-reporting, medications history, and the approval of the cohort center physician following patients' examination. The odds ratio (OR) of joint stiffness in fully adjusted model was greater in the upper median of dietary acidity than in the lower median (PRAL: odds ratio [OR], 1.18; 95% confidence interval [CI], 0.59-2.36), but there was no statistically significant difference. The OR of joint pain in the upper median of dietary acidity was less than in the lower median in fully adjusted model (PRAL: OR, 0.70; 95% CI, 0.46-1.29), but the difference was not statistically significant. After adjusting potential confounders, people in the upper median of dietary acidity had a higher OR of developing RA than those in the lower median (PRAL: OR, 1.39; 95% CI, 0.70-2.76); however, it was not statistically significant. There was not any statistically significant relationship among dietary acidity and the odds of joint pain, joint stiffness, and developing RA.","PeriodicalId":72617,"journal":{"name":"Clinical nutrition research","volume":"11 4","pages":"277-288"},"PeriodicalIF":0.0,"publicationDate":"2022-10-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/70/f3/cnr-11-277.PMC9633968.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40704737","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Use of Complementary and Alternative Medicine (CAM) in Patients With Colorectal Cancer. 大肠癌患者使用补充和替代医学 (CAM)。

Clinical nutrition research Pub Date : 2022-10-27 eCollection Date: 2022-10-01 DOI: 10.7762/cnr.2022.11.4.255

Jeongwon Yeom, Jung Mi Lee

{"title":"Use of Complementary and Alternative Medicine (CAM) in Patients With Colorectal Cancer.","authors":"Jeongwon Yeom, Jung Mi Lee","doi":"10.7762/cnr.2022.11.4.255","DOIUrl":"10.7762/cnr.2022.11.4.255","url":null,"abstract":"This study was conducted to analyze the relationship between cancer-related stress and the types of complementary and alternative medicine (CAM) used by subjects diagnosed with colorectal cancer. The number of study subjects was 142, and for data analysis, descriptive statistics, t-test, χ2 test, logistic regression procedures were performed. Of the subjects, 114 were CAM users, who accounted for 79.6%. When it came to using CAM, 82 (72.6%) said they did \"to prevent cancer recurrence.\" The most popular reason for not using CAM was \"to focus on treatment as instructed by the doctor,\" with 22 (75.8%) respondents selecting the answer. Of those who used CAM, 79 (55.6%) said they took \"dietary supplements,\" followed by 65 (45.8%) who picked \"vitamins and minerals.\" Regarding CAM usage, ginger, aloe, swimming, and walking had the highest satisfaction (4.25 ± 0.71). The cancer-related stress of subjects who use CAM (18.21 ± 15.37) was higher than that of subjects who did not use CAM (10.11 ± 12.08). Logistic regression analysis determined that cancer-related stress were factors significantly associated with CAM use. Patients using CAM had higher cancer-related stress, suggesting that stress on cancer increased CAM interest. Safe and reliable CAM information and standardized recommendations should be provided to cancer survivors. We propose the development of training programs for CAM to improve communication between medical staff and patients and to protect patients.","PeriodicalId":72617,"journal":{"name":"Clinical nutrition research","volume":"11 4","pages":"255-263"},"PeriodicalIF":0.0,"publicationDate":"2022-10-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/fa/db/cnr-11-255.PMC9633969.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40687680","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Iron Homeostasis and Energy Metabolism in Obesity. 肥胖中的铁稳态和能量代谢。

Clinical nutrition research Pub Date : 2022-10-27 eCollection Date: 2022-10-01 DOI: 10.7762/cnr.2022.11.4.316

Se Lin Kim, Sunhye Shin, Soo Jin Yang

{"title":"Iron Homeostasis and Energy Metabolism in Obesity.","authors":"Se Lin Kim, Sunhye Shin, Soo Jin Yang","doi":"10.7762/cnr.2022.11.4.316","DOIUrl":"https://doi.org/10.7762/cnr.2022.11.4.316","url":null,"abstract":"Iron plays a role in energy metabolism as a component of vital enzymes and electron transport chains (ETCs) for adenosine triphosphate (ATP) synthesis. The tricarboxylic acid (TCA) cycle and oxidative phosphorylation are crucial in generating ATP in mitochondria. At the mitochondria matrix, heme and iron-sulfur clusters are synthesized. Iron-sulfur cluster is a part of the aconitase in the TCA cycle and a functional or structural component of electron transfer proteins. Heme is the prosthetic group for cytochrome c, a principal component of the respiratory ETC. Regarding fat metabolism, iron regulates mitochondrial fat oxidation and affects the thermogenesis of brown adipose tissue (BAT). Thermogenesis is a process that increases energy expenditure, and BAT is a tissue that generates heat via mitochondrial fuel oxidation. Iron deficiency may impair mitochondrial fuel oxidation by inhibiting iron-containing molecules, leading to decreased energy expenditure. Although it is expected that impaired mitochondrial fuel oxidation may be restored by iron supplementation, its underlying mechanisms have not been clearly identified. Therefore, this review summarizes the current evidence on how iron regulates energy metabolism considering the TCA cycle, oxidative phosphorylation, and thermogenesis. Additionally, we relate iron-mediated metabolic regulation to obesity and obesity-related complications.","PeriodicalId":72617,"journal":{"name":"Clinical nutrition research","volume":"11 4","pages":"316-330"},"PeriodicalIF":0.0,"publicationDate":"2022-10-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/a8/36/cnr-11-316.PMC9633967.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40687682","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 3

Self-care Through Dynamic Appetite Alteration: A Grounded Theory Study of Patient Experience on Maintenance Hemodialysis. 通过动态食欲改变的自我护理:维持性血液透析患者体验的扎根理论研究。

Clinical nutrition research Pub Date : 2022-10-26 eCollection Date: 2022-10-01 DOI: 10.7762/cnr.2022.11.4.264

Wonsun Hwang, Ji-Hyun Lee, Juha Nam, Jieun Oh, Inwhee Park, Mi Sook Cho

{"title":"Self-care Through Dynamic Appetite Alteration: A Grounded Theory Study of Patient Experience on Maintenance Hemodialysis.","authors":"Wonsun Hwang, Ji-Hyun Lee, Juha Nam, Jieun Oh, Inwhee Park, Mi Sook Cho","doi":"10.7762/cnr.2022.11.4.264","DOIUrl":"https://doi.org/10.7762/cnr.2022.11.4.264","url":null,"abstract":"Hemodialysis (HD) patients can experience appetite alterations that affect meals and nutritional status. Few qualitative studies have assessed the chronic impact of HD on the everyday diet. This study aimed to characterise comprehensively the experiences of HD patients adapting to appetite alteration. Semi-structured, face-to-face interviews were conducted in a unit of a tertiary hospital to understand patient experiences with appetite alteration. An interview guide was used to consider adaptive processes developed after reviewing the literature and based on the researchers' clinical experiences. A single researcher conducted all interviews to maintain consistency in data collection. The interview content was analysed using Nvivo 11 based on grounded theory and constant comparison analysis. As a results, the mean age and HD vintage of 14 participants were 60 and 5.8 years, respectively. We developed a self-care model based on HD patient experiences with appetite alteration based on axial and selective coding. Differences in urea sensitivity, taste alteration, and social support could be explained by timing of transitions, life events, and responses to stress. Self-care processes are adapted through the processes of \"self-registration\" and \"self-reconstruction,\" starting with \"disruption.\" At the stage of adjustment, 4 self-management types were derived based on pattern of self-care: self-initiator, follower, realist, and pessimist. The results of this study provide unique qualitative insight into the lived experiences of HD patients experiencing appetite alteration and their self-care processes. By recognising dietary challenges, health teams can better support HD patients in the transition from dietary education to self-care.","PeriodicalId":72617,"journal":{"name":"Clinical nutrition research","volume":"11 4","pages":"264-276"},"PeriodicalIF":0.0,"publicationDate":"2022-10-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/65/ba/cnr-11-264.PMC9633972.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40687683","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

Obesity, Diabetes Mellitus, and Metabolic Syndrome: Review in the Era of COVID-19. 肥胖、糖尿病和代谢综合征:在COVID-19时代的回顾

Clinical nutrition research Pub Date : 2022-10-24 eCollection Date: 2022-10-01 DOI: 10.7762/cnr.2022.11.4.331

Behnaz Abiri, Amirhossein Ramezani Ahmadi, Mahdi Hejazi, Shirin Amini

引用次数: 4

The Effects of Capsinoids and Fermented Red Pepper Paste Supplementation on Lipid Profile: A Systematic Review and Meta-Analysis of Randomized Controlled Trials. 补充辣椒素和发酵红辣椒酱对血脂的影响:随机对照试验的系统评价和荟萃分析。

Clinical nutrition research Pub Date : 2022-10-24 eCollection Date: 2022-10-01 DOI: 10.7762/cnr.2022.11.4.302

Mohammad Reza Amini, Nastaran Payandeh, Fatemeh Sheikhhossein, Mohsen Alvani, Alireza Talebyan, Fatemeh Mohtashaminia, Azita Hekmatdoost

{"title":"The Effects of Capsinoids and Fermented Red Pepper Paste Supplementation on Lipid Profile: A Systematic Review and Meta-Analysis of Randomized Controlled Trials.","authors":"Mohammad Reza Amini, Nastaran Payandeh, Fatemeh Sheikhhossein, Mohsen Alvani, Alireza Talebyan, Fatemeh Mohtashaminia, Azita Hekmatdoost","doi":"10.7762/cnr.2022.11.4.302","DOIUrl":"https://doi.org/10.7762/cnr.2022.11.4.302","url":null,"abstract":"The present systematic review and meta-analysis were conducted in order to investigate the effects of capsinoids and fermented red pepper paste (FRPP) supplementation on lipid profile. Relevant studies were identified by searches of five databases from inception to November 2021 using relevant keywords. All clinical trials investigating the effect of capsinoids and FRPP on total cholesterol (TC), triglycerides (TG), high-density lipoprotein cholesterol (HDL-C), and low-density lipoprotein cholesterol (LDL-C) were included. Out of 1,203 citations, eight trials that enrolled 393 participants were included. Capsinoids and FRPP resulted in a significant reduction in TC (weighted mean differences [WMD], -9.92 mg/dL; 95% confidence interval [CI], -17.92 to -1.92; p = 0.015) but no significant changes in TG (WMD, -19.38 mg/dL; 95% CI, -39.94 to 1.18; p = 0.065), HDL-C (WMD, 0.83 mg/dL; 95% CI, -0.76 to 2.42; p = 0.305) and LDL-C (WMD, -0.59 mg/dL; 95% CI, -4.96 to 3.79; p = 0.793). Greater effects on TC were detected in trials performed on duration lasting less than twelve weeks, mean age of > 40, both sexes, and sample size of > 50. TG was reduced by using FRPP in studies conducted on mean age of > 40. HDL-C increased by using FRPP in studies conducted on duration of < 12 weeks, mean age of > 40, and sample size of ≤ 50. Overall, these data provided evidence that capsinoids and FRPP supplementation has beneficial effects on TC but not TG, HDL-C, and LDL-C.","PeriodicalId":72617,"journal":{"name":"Clinical nutrition research","volume":"11 4","pages":"302-315"},"PeriodicalIF":0.0,"publicationDate":"2022-10-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/69/f1/cnr-11-302.PMC9633970.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40704735","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 8