Clinical nutrition research最新文献_第10页

Direct-to-Consumer Genetic Testing in Korea: Current Status and Significance in Clinical Nutrition. 韩国直接面向消费者的基因检测:临床营养的现状和意义。

Clinical nutrition research Pub Date : 2021-10-22 eCollection Date: 2021-10-01 DOI: 10.7762/cnr.2021.10.4.279

Ga Young Lee, Sung Nim Han

{"title":"Direct-to-Consumer Genetic Testing in Korea: Current Status and Significance in Clinical Nutrition.","authors":"Ga Young Lee, Sung Nim Han","doi":"10.7762/cnr.2021.10.4.279","DOIUrl":"https://doi.org/10.7762/cnr.2021.10.4.279","url":null,"abstract":"Direct-to-consumer genetic testing (DTC-GT) provides a means for consumers to gain insights into their genetic background and how it relates to their health without the involvement of medical institutions. In Korea, DTC-GT was introduced in 2016 in accordance with the legislation on Paragraph (3) 2 of Article 50 of the Bioethics and Safety Act. Only 12 genetic test items involving 46 genes were approved at first, but the approved items were expanded to 70 in November 2020. However, the genetic test items of DTC-GT services in Korea are still restricted to the wellness area, and access to disease risk related information is only permitted to medical institutions. Further, studies revealing the relationship between genotype differences and responses to nutrients, food components, or nutritional status are increasing, and this association appears to be robust for some genes. This strong association between genetic variations and nutrition suggests that DTC-GT can be used as an important tool by clinical nutritionists to gain insights into an individual's genetic susceptibilities and provide guidance on nutritional counseling and meal planning based on the patient's genetic information. This review summarized the history and current status of DTC-GT and investigated the relationship between genetic variations with associated phenotypic traits to clarify further the importance of DTC-GT in the field of clinical nutrition.","PeriodicalId":72617,"journal":{"name":"Clinical nutrition research","volume":" ","pages":"279-291"},"PeriodicalIF":0.0,"publicationDate":"2021-10-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/f3/4f/cnr-10-279.PMC8575646.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39638386","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 2

Irisin Acts via the PGC-1α and BDNF Pathway to Improve Depression-like Behavior. 鸢尾素通过PGC-1α和BDNF通路改善抑郁样行为

Clinical nutrition research Pub Date : 2021-10-20 eCollection Date: 2021-10-01 DOI: 10.7762/cnr.2021.10.4.292

Danbi Jo, Juhyun Song

{"title":"Irisin Acts via the PGC-1α and BDNF Pathway to Improve Depression-like Behavior.","authors":"Danbi Jo, Juhyun Song","doi":"10.7762/cnr.2021.10.4.292","DOIUrl":"https://doi.org/10.7762/cnr.2021.10.4.292","url":null,"abstract":"Depression is the most prevalent psychiatric disorder experienced by the world's population. Mechanisms associated with depression-like behavior have not been fully investigated. Among the therapeutic solution for depression, exercise is considered an important regulator attenuating depressive neuropathology. Exercise has been reported to boost the secretion of myokines such as irisin and myostatin in skeletal muscles. Myokines secreted during exercise are involved in various cellular responses including the endocrine and autocrine systems. Especially, irisin as a cleaved version of fibronectin domain-containing protein 5 has multiple functions such as white fat-browning, energy expenditure increase, anti-inflammatory effects, and mitochondrial function improvement in both systemic circulation and central nervous system. Furthermore, irisin activates energy metabolism-related signaling peroxisome proliferator-activated receptor-gamma coactivator-1 alpha and memory formation-related signaling brain-derived neurotrophic factor involved in depression. However, the role and mechanism of irisin in depression disorder is not obvious until now. Here, we review recent evidences regarding the therapeutic effect of irisin in depression disorder. We suggest that irisin is a key molecule that suppresses several neuropathological mechanisms involved in depression.","PeriodicalId":72617,"journal":{"name":"Clinical nutrition research","volume":" ","pages":"292-302"},"PeriodicalIF":0.0,"publicationDate":"2021-10-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/20/04/cnr-10-292.PMC8575642.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39638387","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 10

Macro- and Micro-nutrient Intake Adequacy in Gastric Bypass Patients after 24 Months: a Cross-sectional Study. 胃分流术患者24个月后宏量和微量营养素摄入充足性:一项横断面研究。

Clinical nutrition research Pub Date : 2021-10-01 DOI: 10.7762/cnr.2021.10.4.341

Andisheh Norouzian Ostad, Hanieh Barghchi, Ali Jangjoo, Golnaz Ranjbar, Reza Rezvani, Leila Sadat Bahrami, Ladan Goshayeshi, Majid Khadem-Rezaiyan, Mohsen Nematy

{"title":"Macro- and Micro-nutrient Intake Adequacy in Gastric Bypass Patients after 24 Months: a Cross-sectional Study.","authors":"Andisheh Norouzian Ostad, Hanieh Barghchi, Ali Jangjoo, Golnaz Ranjbar, Reza Rezvani, Leila Sadat Bahrami, Ladan Goshayeshi, Majid Khadem-Rezaiyan, Mohsen Nematy","doi":"10.7762/cnr.2021.10.4.341","DOIUrl":"https://doi.org/10.7762/cnr.2021.10.4.341","url":null,"abstract":"Decreased food intake is an effective mechanism for gastric bypass surgery (GBS) for successful weight loss. This cross-sectional study aimed to assess dietary intake, micro-and macro-nutrients in the patients undergoing GBS and determine the possible associations with weight changes. We assessed anthropometric indices and food intake at 24 month-post gastric bypass surgery. Dietary data was evaluated using three-day food records. After the 24 months of surgery, among 35 patients (mean age: 43.5 ± 11.2 years; 82.85% females), with the mean body mass index (BMI) of 30.5 ± 4.5 kg/m2, 17 cases were < 50% of their excess weight. The average daily calorie intake was 1,733 ± 630 kcal, with 14.88% of calories from protein. Consumption amounts of protein (0.82 ± 0.27 g/kg of the current weight), as well as fiber, and some micro-nutrients (vitamin B9, E, K, B5, and D3) were lower than recommended amounts. Patients were classified into three groups based on their success in weight loss after surgery. Calorie intake was not significantly different between groups, but successful groups consumed considerably more protein and less carbohydrate than the unsuccessful group (p < 0.05). Based on our findings, the patients undergoing GBS had inadequate macro- and micro-nutrient intake after 24 months. However, protein intake can affect patients' success in achieving better weight loss. Long-term cohort and clinical studies need to be conducted to comprehend this process further.","PeriodicalId":72617,"journal":{"name":"Clinical nutrition research","volume":"10 4","pages":"341-352"},"PeriodicalIF":0.0,"publicationDate":"2021-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/8f/d0/cnr-10-341.PMC8575647.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10541572","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

Relationship between Adipose Tissue Derived Hormones and Cardiometabolic Risk according to Obesity Status. 肥胖状态下脂肪源性激素与心脏代谢风险的关系

Clinical nutrition research Pub Date : 2021-07-30 eCollection Date: 2021-07-01 DOI: 10.7762/cnr.2021.10.3.206

So Yoon Hwang, Min Joo Seon, Jong Hwa Lee, Oh Yoen Kim

{"title":"Relationship between Adipose Tissue Derived Hormones and Cardiometabolic Risk according to Obesity Status.","authors":"So Yoon Hwang, Min Joo Seon, Jong Hwa Lee, Oh Yoen Kim","doi":"10.7762/cnr.2021.10.3.206","DOIUrl":"https://doi.org/10.7762/cnr.2021.10.3.206","url":null,"abstract":"Adiponectin, and leptin are adipose tissue derived hormones affecting metabolic status. This study aimed to investigate the relationship between circulating adiponectin and leptin levels, and cardiometabolic parameters by obesity status among healthy women without metabolic disease. Finally 141 participants were included in the analyses and categorized into three groups by their body mass index (kg/m2) (normal weight: 18.5 ≤ body mass index [BMI] < 23.0, n=65; overweight: 23.0 ≤ BMI < 25.0, n=26; obesity: 25.0 ≤ BMI, n=50). Overweight and obesity groups were older, and had significantly higher levels of adiposity, blood pressure, fasting glucose, triglyceride, and high sensitivity C-reactive protein (hs-CRP), and lower levels of high density lipoprotein (HDL)-cholesterol than normal weight group. Circulating leptin levels, and leptin to adiponectin ratio were highest in obesity group, but circulating adiponectin levels were not statistically different among the three groups. Circulating leptin levels were negatively correlated with adiponectin levels, and leptin to adiponectin ratio. In addition, leptin levels were positively correlated with waist circumference, systolic blood pressure, insulin resistance, and hs-CRP, and negatively with HDL-cholesterol. However, circulating adiponectin levels were negatively correlated only with waist circumference, and hs-CRP. These patterns were retained after adjusted for confounding factors such as age, smoking and drinking habits, menopausal status and total calorie intake. In conclusion, circulating adiponectin and leptin levels according to obesity status were differently observed among healthy women, and circulating leptin levels may be a more sensitive parameter for cardiometabolic risk in healthy women.","PeriodicalId":72617,"journal":{"name":"Clinical nutrition research","volume":"10 3","pages":"206-218"},"PeriodicalIF":0.0,"publicationDate":"2021-07-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/48/58/cnr-10-206.PMC8331290.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39306303","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The Effect of Garlic (Allium sativum L) Supplementation on Circulating Adiponectin: a Systematic Review and Meta-Analysis of Randomized Controlled Trials. 大蒜(Allium sativum L)补充对循环脂联素的影响:随机对照试验的系统评价和荟萃分析。

Clinical nutrition research Pub Date : 2021-07-30 eCollection Date: 2021-07-01 DOI: 10.7762/cnr.2021.10.3.257

Shima Sharifi, Sepide Talebi, Elyas Nattagh-Eshtivani, Yasaman Amiri, Gholamreza Askari

{"title":"The Effect of Garlic (Allium sativum L) Supplementation on Circulating Adiponectin: a Systematic Review and Meta-Analysis of Randomized Controlled Trials.","authors":"Shima Sharifi, Sepide Talebi, Elyas Nattagh-Eshtivani, Yasaman Amiri, Gholamreza Askari","doi":"10.7762/cnr.2021.10.3.257","DOIUrl":"https://doi.org/10.7762/cnr.2021.10.3.257","url":null,"abstract":"Our aim was to conduct a systematic review and meta-analysis on randomized controlled trials (RCTs) evaluating the effect of garlic on serum adiponectin levels. We searched Scopus, Web of Science, PubMed, and Cochrane Library to databases up to January 2021. RCTs investigating the effects of garlic on serum adiponectin levels in adult participants were included. The change in serum adiponectin levels was estimated using weighted mean differences (WMD) and standard deviations (SD). The random effects model was used to provide a summary of mean estimates and their SDs. Out of 386 records, 6 trials with 8 arms treatment which enrolled 266 subjects were included. Garlic supplementation resulted in a non-significant increase in adiponectin concentrations when compared to placebo, according to the pooled data (WMD, 0.27 Hedges' g; 95% confidence interval [CI], -0.07, 0.62; p = 0.124). Greater effects on adiponectin were observed in trials with supplementation dose less than 1.5 gram per day (WMD, 0.71 Hedges' g; 95% CI, -0.01, 1.43; p = 0.600) and in trials with female subset (WMD, 0.62 Hedges' g; 95% CI, -0.96, 2.21; p = 0.441). Garlic boosts adiponectin levels in general. However, due to different target population, various units for reporting adiponectin level and few eligible studies in final analysis, more research is needed to get a firm conclusion about the influence of garlic on adiponectin levels.","PeriodicalId":72617,"journal":{"name":"Clinical nutrition research","volume":"10 3","pages":"257-267"},"PeriodicalIF":0.0,"publicationDate":"2021-07-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/30/dc/cnr-10-257.PMC8331287.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39306307","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

Dietitians View of Foodservice Sanitary Practices and Demands in Long-Term Care Hospitals. 长期护理医院食品服务卫生实践和需求的营养师观点。

Clinical nutrition research Pub Date : 2021-07-30 eCollection Date: 2021-07-01 DOI: 10.7762/cnr.2021.10.3.192

Jeonghyeon Woo, Hee-Sook Lim, Hee-Joon Baek, Dal Lae Ju, Youri Jin, Jieun Lee, Hwayoung Yoon, Wan-Soo Hong, Yoo Kyoung Park

{"title":"Dietitians View of Foodservice Sanitary Practices and Demands in Long-Term Care Hospitals.","authors":"Jeonghyeon Woo, Hee-Sook Lim, Hee-Joon Baek, Dal Lae Ju, Youri Jin, Jieun Lee, Hwayoung Yoon, Wan-Soo Hong, Yoo Kyoung Park","doi":"10.7762/cnr.2021.10.3.192","DOIUrl":"https://doi.org/10.7762/cnr.2021.10.3.192","url":null,"abstract":"This study aimed to investigate the current state of foodservice management and demands for improvement in long-term care hospitals. The survey was performed in experienced dietitians working at 25 hospitals. General characteristics, status of sanitary management (document management, self-assessment of importance and performance), necessity and ranking of sanitary management items were investigated. Approximately 2.5 dietitians worked in each hospital, but only 7 (28.0%) hospitals employed clinical dietitians. From the questionnaire, the scores of the importance in sanitary management and performance were 4.5 ± 0.7 and 4.3 ± 0.9, respectively, and were significantly different (p = 0.000). Participants also reported “special therapeutic diets management” and “compliance with standards of refrigerating time, food, method management” had the lowest importance and performance, respectively. The result of Importance-Performance Analysis revealed a significant positive correlation between importance and performance (R2 = 0.427). However, items such as “performing hand hygiene” and “compliance with standards of refrigerating time, food, method” and etc. had low importance recognition with low performance. All participants reported “preparing sanitary management standards was necessary” is necessary and “development of sanitary management manual” is the most important. These findings suggest that sanitary management is important in food service management of long-term care hospitals, and improving awareness is required. Developing a hospital foodservice hygiene manual would ensure better safety and quality for patient care and public health.","PeriodicalId":72617,"journal":{"name":"Clinical nutrition research","volume":"10 3","pages":"192-205"},"PeriodicalIF":0.0,"publicationDate":"2021-07-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/09/36/cnr-10-192.PMC8331285.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39305865","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Predictors of Childhood High Blood Pressure among Overweight and Obese Children and Adolescents according to the Lifestyle-Scoring Algorithm Using Data from Iranian Health Care Reform Plan. 根据伊朗医疗改革计划数据的生活方式评分算法，超重和肥胖儿童和青少年儿童高血压的预测因素

Clinical nutrition research Pub Date : 2021-07-26 eCollection Date: 2021-07-01 DOI: 10.7762/cnr.2021.10.3.243

Shahnaz Taghizadeh, Mahdieh Abbasalizad-Farhangi, Fathollah Pourali, Mohammad Asghari-Jafarabadi

{"title":"Predictors of Childhood High Blood Pressure among Overweight and Obese Children and Adolescents according to the Lifestyle-Scoring Algorithm Using Data from Iranian Health Care Reform Plan.","authors":"Shahnaz Taghizadeh, Mahdieh Abbasalizad-Farhangi, Fathollah Pourali, Mohammad Asghari-Jafarabadi","doi":"10.7762/cnr.2021.10.3.243","DOIUrl":"https://doi.org/10.7762/cnr.2021.10.3.243","url":null,"abstract":"In this study, the association between dietary pattern and lifestyle in predicting hypertension (HTN) among 425 overweight and obese children and adolescents aged 6 to 18 years was evaluated. In the current cross-sectional study, the lifestyle-scoring algorithm was developed considering the Iranian Health Reform Plan (HRP) criterion. HTN was defined according to standard protocols. Hierarchical linear regression models were used for the analysis. The prevalence of overweight/obesity was 5.82%. The results showed that systolic and diastolic blood pressure (SBP, DBP) had significant positive correlation with age (p < 0.001 and p < 0.001) and body mass index (BMI) (p < 0.005 and p < 0.007), respectively. Moreover, DBP had a significant correlation with fruit consumption of less than 2 servings per day versus no consumption (p = 0.014, B = 0.444), fruit consumption of more than 2 servings per day versus no consumption (p = 0.014, B = 0.480), and vegetable consumption less than 3 servings per day versus no consumption (p = 0.045, B = -0.374). Moreover, DBP had a significant correlation with fast foods/junk foods consumption of 1-2 items per week versus almost daily consumption (p = 0.047, B = -0.177). The final model could predict 32.1% of HTN by SBP and DBP (R2 = 0.32). According to our findings, lower intake of vegetables and fruits, higher amounts of fast foods, higher age and BMI could be potent predictors of high blood pressure among Iranian children and adolescents.","PeriodicalId":72617,"journal":{"name":"Clinical nutrition research","volume":"10 3","pages":"243-256"},"PeriodicalIF":0.0,"publicationDate":"2021-07-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/f4/02/cnr-10-243.PMC8331284.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39306306","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 2

The Effect of Pyridoxine Hydrochloride Supplementation on Leptin, Adiponectin, Glycemic Indices, and Anthropometric Indices in Obese and Overweight Women. 补充盐酸吡哆醇对肥胖和超重妇女瘦素、脂联素、血糖指数和人体测量指标的影响。

Clinical nutrition research Pub Date : 2021-07-22 eCollection Date: 2021-07-01 DOI: 10.7762/cnr.2021.10.3.230

Fatemeh Haidari, Majid Mohammadshahi, Mehdi Zarei, Mohammad Hosein Haghighizadeh, Fatemeh Mirzaee

{"title":"The Effect of Pyridoxine Hydrochloride Supplementation on Leptin, Adiponectin, Glycemic Indices, and Anthropometric Indices in Obese and Overweight Women.","authors":"Fatemeh Haidari, Majid Mohammadshahi, Mehdi Zarei, Mohammad Hosein Haghighizadeh, Fatemeh Mirzaee","doi":"10.7762/cnr.2021.10.3.230","DOIUrl":"https://doi.org/10.7762/cnr.2021.10.3.230","url":null,"abstract":"Obesity has reached epidemic proportions globally. Among several methods for treating obesity, the use of dietary supplements is common recently. One supplement that can help in this regard might be vitamin B6 in high doses. The objective of this study was to evaluate the effect of pyridoxine hydrochloride supplementation on anthropometric indices, body composition, visceral adiposity index (VAI), and metabolic status in obese and overweight women. In this randomized controlled clinical trial, 44 obese and overweight women aged 18-50 years were selected and divided randomly into 2 groups: an intervention group (receiving 80 mg pyridoxine hydrochloride supplement for 8 weeks) and a control group (receiving placebo for 8 weeks). In the pyridoxine hydrochloride group, weight (p = 0.03), body mass index (p = 0.023), fat mass (p = 0.003), waist circumference (p = 0.005), VAI (p = 0.001), fasting insulin, insulin resistance (homeostasis model assessment of insulin resistance; HOMA-IR), total cholesterol, low-density lipoprotein, triglycerides (TG) and leptin (p < 0.001) decreased whereas adiponectin (p < 0.001) increased in comparison to the baseline values. There was a significant difference in fat mass, VAI, fasting insulin, HOMA-IR, and TG between pyridoxine hydrochloride and control groups following intervention in adjusted models (p < 0.05). The findings suggest that vitamin B6 supplementation may be effective in reducing BMI and improving body composition and biochemical factors associated with obesity.Trial registration: Iranian Registry of Clinical Trials Identifier: IRCT20181002041206N1.","PeriodicalId":72617,"journal":{"name":"Clinical nutrition research","volume":"10 3","pages":"230-242"},"PeriodicalIF":0.0,"publicationDate":"2021-07-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/0d/40/cnr-10-230.PMC8331291.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39306305","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 2

Nutritional Management in a Patient with Citrullinemia Type 1. 1型瓜氨酸血症患者的营养管理。

Clinical nutrition research Pub Date : 2021-07-20 eCollection Date: 2021-07-01 DOI: 10.7762/cnr.2021.10.3.268

Hyejin Kang, Mihyang Kim, Ji Hyun Lee

引用次数: 2

Vitamin D and The Gut Microbiota: a Narrative Literature Review. 维生素D与肠道微生物群:叙述性文献综述。

Clinical nutrition research Pub Date : 2021-07-20 eCollection Date: 2021-07-01 DOI: 10.7762/cnr.2021.10.3.181

Hadith Tangestani, Hossein Khosravi Boroujeni, Kurosh Djafarian, Hadi Emamat, Sakineh Shab-Bidar

{"title":"Vitamin D and The Gut Microbiota: a Narrative Literature Review.","authors":"Hadith Tangestani, Hossein Khosravi Boroujeni, Kurosh Djafarian, Hadi Emamat, Sakineh Shab-Bidar","doi":"10.7762/cnr.2021.10.3.181","DOIUrl":"https://doi.org/10.7762/cnr.2021.10.3.181","url":null,"abstract":"Recently several studies have attempted to investigate the association between vitamin D and microbiota. However, studies have reported inconsistent results. This narrative review aimed to investigate the potential association between vitamin D and microbiota population in the gut by pooling together the results from observational studies and clinical trials. We considered animal and human studies in this field. Several studies have shown the correlation of vitamin D deficiency with microbiota. Furthermore, interventional studies were emerging that vitamin D change the microbiota composition in which leads to an increase in beneficial bacteria, such as Ruminococcaceae, Akkermansia, Faecalibacterium, and Coprococcus while decreases in Firmicutes. Vitamin D could change the microbiota toward decreasing in Firmicutes and increasing in Bacteroidetes. At genera level, vitamin D may connect to some genera of Lachnospiaceae family (e.g., Blautia, Rosburia, Dorea, and Coprococcus). It seems that adequate level of vitamin D is an important factor in improving the composition of the gut microbiota. More studies are needed to confirm possible underling mechanisms.","PeriodicalId":72617,"journal":{"name":"Clinical nutrition research","volume":"10 3","pages":"181-191"},"PeriodicalIF":0.0,"publicationDate":"2021-07-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/80/32/cnr-10-181.PMC8331286.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39306302","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 19