Clinical nutrition research最新文献

Effects of oral supplementation with whey protein concentrate and its hydrolysates on blood cholesterol levels and oxidative DNA damage in South Korean male smokers. 口服补充浓缩乳清蛋白及其水解物对韩国男性吸烟者血液胆固醇水平和氧化性DNA损伤的影响。

Clinical nutrition research Pub Date : 2026-01-01 Epub Date: 2026-01-31 DOI: 10.7762/cnr.2026.0001

Ji Yeon Paik, Seung-Min Lee, Eunju Park

{"title":"Effects of oral supplementation with whey protein concentrate and its hydrolysates on blood cholesterol levels and oxidative DNA damage in South Korean male smokers.","authors":"Ji Yeon Paik, Seung-Min Lee, Eunju Park","doi":"10.7762/cnr.2026.0001","DOIUrl":"10.7762/cnr.2026.0001","url":null,"abstract":"Objective: Cigarette smoking leads to oxidative stress and high cholesterolemia, which are key drivers of cardiovascular disease (CVD). Whey is known for its antioxidant and hypolipidemic properties. This study investigated whether whey protein concentrate (WPC) and hydrolysate of WPC (HWPC) can alleviate CVD risk in South Korean smokers by lowering oxidative stress and blood lipids.Methods: A total of 25 male smokers were screened, of which 18 eligible participants (72.0%), randomly assigned to either the WPC (n=9) or the HWPC (n=9) group, completed the 8-week intervention. Before (week 0, baseline) and after the intervention, participants visited the laboratory for blood collection and anthropometric measurements (body weight, height, waist circumference, body fat mass, nutritional intake). Blood samples were analyzed for plasma lipid profiles, plasma fat-soluble antioxidants, and leukocyte oxidative DNA damage using the comet assay.Results: There were no significant differences in anthropometric measurements, dietary food intake, plasma conjugated dienes, total radical-trapping antioxidant potential, and erythrocytes' glutathione peroxidase and catalase activities in both WPC and HWPC groups. However, we observed a significant decrease in the tail moments of leukocytes, low-density lipoprotein cholesterol, atherogenic index, and high coenzyme Q10 levels in both groups. In the WPC group, total cholesterol decreased, while plasma retinol, α-tocopherol, lycopene, α-carotene, and β-carotene increased.Conclusion: WPC or HWPC significantly decreases blood cholesterol levels and oxidative DNA damage and increases plasma fat-soluble antioxidant levels. Thus, WPC or HWPC might be used as oral supplementation to lower the risk for CVD in South Korean male smokers.","PeriodicalId":72617,"journal":{"name":"Clinical nutrition research","volume":"15 1","pages":"25-35"},"PeriodicalIF":0.0,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13007808/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147470379","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Effects of propolis supplementation on blood glucose and lipid profiles in individuals with metabolic syndrome and type 2 diabetes: a systematic review and meta-analysis. 蜂胶补充对代谢综合征和2型糖尿病患者血糖和血脂的影响：一项系统综述和荟萃分析

Clinical nutrition research Pub Date : 2026-01-01 Epub Date: 2026-01-31 DOI: 10.7762/cnr.2025.0004

Ezatollah Fazeli Moghadam, Elham Afshari, Leili Khaghani, Parivash Shekarchizadeh-Esfahani

{"title":"Effects of propolis supplementation on blood glucose and lipid profiles in individuals with metabolic syndrome and type 2 diabetes: a systematic review and meta-analysis.","authors":"Ezatollah Fazeli Moghadam, Elham Afshari, Leili Khaghani, Parivash Shekarchizadeh-Esfahani","doi":"10.7762/cnr.2025.0004","DOIUrl":"10.7762/cnr.2025.0004","url":null,"abstract":"Objective: Propolis has been suggested as a complementary therapy for improving glycemic control and lipid metabolism. However, evidence from clinical trials remains inconsistent. This systematic review and meta-analysis aimed to provide a clear and updated assessment of the effects of propolis supplementation on fasting blood sugar (FBS) and lipid profiles in individuals with type 2 diabetes mellitus (T2DM) and metabolic syndrome (MetS).Methods: A comprehensive search was conducted on the PubMed, Scopus, Cochrane Library, and Web of Science databases through December 2024 to identify randomized controlled trials (RCTs) evaluating the impact of propolis supplementation on FBS and lipid parameters. Eligible data were pooled using a random-effects model, and weighted mean differences (WMDs) were calculated as pooled effect sizes.Results: A total of 12 RCTs were included, encompassing 736 participants. Propolis supplementation significantly reduced FBS (WMD, -12.08 mg/dL; 95% confidence interval [CI], -19.13 to -5.04; P=0.001) and triglyceride (TG) levels (WMD, -25.40 mg/dL; 95% CI, -44.21 to -6.59; P=0.008) without significantly affecting the levels of total cholesterol, low-density lipoprotein cholesterol, and high-density lipoprotein cholesterol.Conclusion: These findings suggest that propolis supplementation may modestly improve glycemic control and reduce TG levels in individuals with T2DM and MetS. However, the limited number of available studies and relatively small sample sizes highlight the need for large, high-quality RCTs to verify these findings and clarify the metabolic effects of propolis.","PeriodicalId":72617,"journal":{"name":"Clinical nutrition research","volume":"15 1","pages":"45-54"},"PeriodicalIF":0.0,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13007807/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147470398","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Effects of meal sequence intervention on blood glucose response in healthy adults: a systematic review. 膳食顺序干预对健康成人血糖反应的影响：一项系统综述

Clinical nutrition research Pub Date : 2026-01-01 Epub Date: 2026-01-31 DOI: 10.7762/cnr.2025.0027

Jinmin Kim, Eun-Hee Jang, Seungmin Lee

{"title":"Effects of meal sequence intervention on blood glucose response in healthy adults: a systematic review.","authors":"Jinmin Kim, Eun-Hee Jang, Seungmin Lee","doi":"10.7762/cnr.2025.0027","DOIUrl":"10.7762/cnr.2025.0027","url":null,"abstract":"Objective: Achieving glycemic control is essential in the prevention and management of metabolic disorders, with several dietary strategies having been proposed. Meal sequence, which is defined as the order of food consumption while maintaining the overall composition and intake, may attenuate postprandial glycemic responses. This systematic review aimed to assess the effects of meal sequences on postprandial glycemic responses in healthy adults and explore its potential as a preventive strategy for glycemic control.Methods: Literature published between January 2015 and March 2025 in PubMed, Cochrane Library, Web of Science, KoreaMed, and RISS was searched using the keywords \"healthy adult,\" \"food order,\" \"meal sequence,\" and \"glucose response.\"Results: Among the 2,442 records identified, one randomized controlled trial, four randomized crossover studies, and one repeated-measures design with a total of 107 participants aged 20-36.7 years met the inclusion criteria. Most of the studies reported that consuming vegetables, fruits, or protein-rich foods before carbohydrate-rich foods reduced postprandial glucose responses and incremental area under the curve compared with mixed or carbohydrate-first meals. These effects were also noted in randomized controlled trials and randomized crossover design.Conclusion: Our findings indicate that adjusting the order of food consumption can effectively mitigate acute postprandial glucose responses in healthy individuals. Further large-scale and long-term randomized controlled trials across diverse populations and standardized protocols are warranted to strengthen the evidence base.","PeriodicalId":72617,"journal":{"name":"Clinical nutrition research","volume":"15 1","pages":"55-63"},"PeriodicalIF":0.0,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13007804/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147470405","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Dietary management of pediatric patients with kidney disease: recommendations by the Korean Society of Pediatric Nephrology and the Korean Society of Clinical Nutrition. 肾病患儿的饮食管理：韩国儿科肾病学会和韩国临床营养学会的建议

Clinical nutrition research Pub Date : 2026-01-01 Epub Date: 2026-01-31 DOI: 10.7762/cnr.2025.0033

Yo Han Ahn, Hee Gyung Kang, Jiyoung Song, Sangmi Han, Eujin Park, Jin-Soon Suh, Jeong Yeon Kim, Min Ji Park, Keum Hwa Lee, Seon Hee Lim, Kyeong Hun Shin, Hyunji Ko, Hyun Joo Lee, Eunyoung Jeong, Jinsu Kim, Sohyun Park, Eonju Choi, Yuri Seo, Kyooyung Oh, Jin Kyoung Kim, Hyun Kyung Lee

{"title":"Dietary management of pediatric patients with kidney disease: recommendations by the Korean Society of Pediatric Nephrology and the Korean Society of Clinical Nutrition.","authors":"Yo Han Ahn, Hee Gyung Kang, Jiyoung Song, Sangmi Han, Eujin Park, Jin-Soon Suh, Jeong Yeon Kim, Min Ji Park, Keum Hwa Lee, Seon Hee Lim, Kyeong Hun Shin, Hyunji Ko, Hyun Joo Lee, Eunyoung Jeong, Jinsu Kim, Sohyun Park, Eonju Choi, Yuri Seo, Kyooyung Oh, Jin Kyoung Kim, Hyun Kyung Lee","doi":"10.7762/cnr.2025.0033","DOIUrl":"10.7762/cnr.2025.0033","url":null,"abstract":"Pediatric kidney disease has a lower prevalence than other pediatric conditions and has a notably different etiology from kidney diseases occurring in adults. Furthermore, the pediatric population is unique in that they experience ongoing growth and development, distinguishing them from adult patients. Consequently, pediatric patients with kidney disease require a more specialized and meticulous nutritional management plan compared with adult patients. To address this need and promote optimal dietary practices for pediatric patients with kidney disease, pediatric nephrologists from the Korean Society of Pediatric Nephrology and nutritionists from the Korean Society of Clinical Nutrition have collaborated to formulate nutritional guidelines specifically tailored to Korean dietary patterns. These guidelines offer detailed, nutrient-specific recommendations regarding the consumption of energy, protein, calcium, phosphorus, and potassium while providing practical, culturally relevant guidance intended to support both pediatric patients and their caregivers.","PeriodicalId":72617,"journal":{"name":"Clinical nutrition research","volume":"15 1","pages":"1-11"},"PeriodicalIF":0.0,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13007806/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147470422","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Comparative nutritional assessment of vegetarian and nonvegetarian ready-to-eat foods. 素食和非素食即食食品的营养比较评估。

Clinical nutrition research Pub Date : 2026-01-01 Epub Date: 2026-01-31 DOI: 10.7762/cnr.2025.0032

Jungeun Park, Su-Ryeon Han, Mi-Kyeong Choi

{"title":"Comparative nutritional assessment of vegetarian and nonvegetarian ready-to-eat foods.","authors":"Jungeun Park, Su-Ryeon Han, Mi-Kyeong Choi","doi":"10.7762/cnr.2025.0032","DOIUrl":"10.7762/cnr.2025.0032","url":null,"abstract":"Objective: This study aimed to assess the nutritional adequacy of vegetarian ready-to-eat convenience foods, focusing on gimbap, rice ball, and sandwich products.Methods: We examined 114 vegetarian and 414 nonvegetarian ready-to-eat products and compared their energy and nutrient contents to gain useful insights for consumers when making informed choices and for producers when developing nutritionally balanced vegetarian convenience foods.Results: Compared with nonvegetarian products, vegetarian convenience foods had a significantly greater carbohydrate content per serving and significantly lower protein, sodium, and cholesterol contents. Although vegetarian gimbap was significantly more costly than the nonvegetarian gimbap, its cholesterol and saturated fat contents were significantly lower. Vegetarian rice balls had a significantly lower trans fat content than their nonvegetarian counterparts. Sandwiches in the vegetarian options had a significantly higher sugars content but had significantly lower protein and sodium contents than those in the nonvegetarian options. Vegetarian convenience foods did not meet one-third of the daily nutrient reference values for a single meal, similar to their nonvegetarian counterparts, but their sodium content exceeded the daily reference value. However, unlike the nonvegetarian options, the sodium content of vegetarian sandwiches did not exceed the daily value.Conclusion: Vegetarian convenience foods contain higher levels of carbohydrates and sugars and lower levels of protein, sodium, and cholesterol than nonvegetarian convenience foods. Foods such as vegetarian gimbap, rice balls, and sandwiches do not provide sufficient energy or nutrients to meet the nutritional requirements for a single meal. Creating nutritionally balanced vegetarian convenience foods should be the focus when developing new vegetarian food products.","PeriodicalId":72617,"journal":{"name":"Clinical nutrition research","volume":"15 1","pages":"36-44"},"PeriodicalIF":0.0,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13007805/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147470472","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Clinical field survey and multidisciplinary expert in-depth interview study on food for special medical purpose products for patients. 临床现场调查与多学科专家深度访谈研究患者专用医疗食品产品。

Clinical nutrition research Pub Date : 2026-01-01 Epub Date: 2026-01-31 DOI: 10.7762/cnr.2026.0002

Ju Hee Kang, Hee-Jung Park, Hyo Jeong Lim, Jung Joo Lee, Bo-Eun Kim, Eun Joo Bae, Yeon Hee Lee, Dal Lae Ju, Young Ran Kim, Jin-Hee Yeom, Hee-Sook Lim, Ha-Neul Kim, Seul Bi Lee, Seo-Yeon Park, Hee Joon Baek, Yoo Kyoung Park

{"title":"Clinical field survey and multidisciplinary expert in-depth interview study on food for special medical purpose products for patients.","authors":"Ju Hee Kang, Hee-Jung Park, Hyo Jeong Lim, Jung Joo Lee, Bo-Eun Kim, Eun Joo Bae, Yeon Hee Lee, Dal Lae Ju, Young Ran Kim, Jin-Hee Yeom, Hee-Sook Lim, Ha-Neul Kim, Seul Bi Lee, Seo-Yeon Park, Hee Joon Baek, Yoo Kyoung Park","doi":"10.7762/cnr.2026.0002","DOIUrl":"10.7762/cnr.2026.0002","url":null,"abstract":"Objective: Food for special medical purpose (FSMP) has become essential in clinical nutrition care. However, comprehensive data on FSMP utilization practices among healthcare professionals in South Korea are limited. This study aimed to investigate perceptions, current practices, and needs regarding FSMP among healthcare professionals.Methods: A mixed-methods approach was employed, combining a cross-sectional survey of 417 healthcare professionals (47 physicians, 219 nurses, and 151 dietitians) from 90 institutions with focus group interviews of 24 Nutrition Support Team members from six institutions. Data were collected from May to October 2025.Results: Substantial interphysician variability was observed in documentation for enteral formula prescriptions. Infusion rates were documented in 9.2% of the physician orders; feeding method was recorded in 14.1%. Across all professional groups, diarrhea was the most common reason for changing enteral formulas (36%-39%). In education related enteral formulas, 59.6% of the physicians expected dietitians to educate patients; however, this role was most commonly performed by nurses (59.8%). Dietitians prioritized hygiene (66.9%) and safety (64.2%) when selecting products, and 84.1% of the institutions were providing oral nutritional supplements.Conclusion: These findings highlight the need for standardized prescription documentation, evidence-based feeding protocols, and clearly defined professional roles in multidisciplinary frameworks, to optimize FSMP utilization.","PeriodicalId":72617,"journal":{"name":"Clinical nutrition research","volume":"15 1","pages":"12-24"},"PeriodicalIF":0.0,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13007802/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147470395","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Nutritional management of an adolescent undergoing bariatric surgery: a case report. 青少年接受减肥手术的营养管理：1例报告。

Clinical nutrition research Pub Date : 2026-01-01 Epub Date: 2026-01-31 DOI: 10.7762/cnr.2025.0035

Yooeun Yoon, Hosun Lee, Soo Min Ahn

{"title":"Nutritional management of an adolescent undergoing bariatric surgery: a case report.","authors":"Yooeun Yoon, Hosun Lee, Soo Min Ahn","doi":"10.7762/cnr.2025.0035","DOIUrl":"10.7762/cnr.2025.0035","url":null,"abstract":"This case report describes the nutritional management and long-term outcomes of an adolescent undergoing bariatric surgery. A 13-year-old female patient with morbid obesity complicated by nonalcoholic steatohepatitis (NASH), impaired glucose tolerance (IGT), and polycystic ovary syndrome (PCOS) underwent sleeve gastrectomy in July 2021. The patient achieved significant weight loss, with a total weight loss of 43.3% and a body mass index reduction of 16.6 kg/m2 at 3 years post-surgery, which further increased to 18.6 kg/m2 by the fourth year. Remission of NASH, IGT, and PCOS was observed after 1 year. Postoperatively, vitamin D deficiency developed, whereas other biochemical parameters remained within normal reference ranges. Adherence to recommended nutritional supplementation was suboptimal; however, with continuous nutritional education and regular follow-up, the patient ultimately established and maintained a balanced dietary pattern. The case highlights the effectiveness of bariatric surgery in achieving sustained weight loss and improving obesity-related comorbidities in adolescents, while underscoring the critical role of continuous nutritional management, patient education, and individualized multidisciplinary care in supporting long-term postoperative success.","PeriodicalId":72617,"journal":{"name":"Clinical nutrition research","volume":"15 1","pages":"64-71"},"PeriodicalIF":0.0,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13007803/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147470417","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Reversing 20 years of diabetes using the carnivore diet in India: a case report. 在印度用食肉动物饮食逆转了20年的糖尿病：一个病例报告。

Clinical nutrition research Pub Date : 2026-01-01 Epub Date: 2026-01-31 DOI: 10.7762/cnr.2025.0026

Ankur Verma

引用次数: 0

Nutrigenomics for Autism Spectrum Disorder: A Multidisciplinary Framework for Personalized Nutrition in Special Education. 自闭症谱系障碍的营养基因组学：特殊教育中个性化营养的多学科框架。

Clinical nutrition research Pub Date : 2025-10-31 eCollection Date: 2025-10-01 DOI: 10.7762/cnr.2025.14.4.329

Jung Min Cho, Joo Won Shin

{"title":"Nutrigenomics for Autism Spectrum Disorder: A Multidisciplinary Framework for Personalized Nutrition in Special Education.","authors":"Jung Min Cho, Joo Won Shin","doi":"10.7762/cnr.2025.14.4.329","DOIUrl":"10.7762/cnr.2025.14.4.329","url":null,"abstract":"Autism spectrum disorder (ASD) is a multifactorial neurodevelopmental condition often accompanied by metabolic and nutritional imbalances. Conventional dietary interventions, such as the gluten-free, casein-free diet, typically fail to consider individual genetic variations. Nutrigenomics, the study of gene-nutrient interactions, offers a promising framework for exploring personalized dietary interventions that may help address the metabolic and neurological complexities associated with ASD, although current evidence remains preliminary. This research note offers recommendations for integrating nutrigenomics into special education through a multidisciplinary approach that combines clinical nutrition, genetics, and educational practice via a 3-phase agenda. Stage 1 focuses on identifying behavioral subgroups within special education settings and using validated tools such as the Child Behavior Checklist Scale to analyze nutritional intake. Stage 2 involves the development and pilot-testing of behavior-specific nutrition protocols that are tailored to these subgroups, incorporating input from practice experts in nutrigenomics. Lastly, in Stage 3, a personalized nutrition model that incorporates genetic screening and metabolic profiling is constructed in collaboration with dietitians, educators, and caregivers. By bridging clinical and educational domains, this study seeks to establish nutrigenomics-based nutrition therapy as a viable and equitable intervention for improving health and developmental outcomes among students with ASD.","PeriodicalId":72617,"journal":{"name":"Clinical nutrition research","volume":"14 4","pages":"329-337"},"PeriodicalIF":0.0,"publicationDate":"2025-10-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12629405/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145566321","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Clinical Impact of Nutritional Intervention on Pressure Injury Healing in a Paraplegic Patient: A Case Report. 营养干预对截瘫患者压伤愈合的临床影响：1例报告。

Clinical nutrition research Pub Date : 2025-10-31 eCollection Date: 2025-10-01 DOI: 10.7762/cnr.2025.14.4.241

Young Ran Kim, Mi Young Jang, Jun Ho Park

{"title":"Clinical Impact of Nutritional Intervention on Pressure Injury Healing in a Paraplegic Patient: A Case Report.","authors":"Young Ran Kim, Mi Young Jang, Jun Ho Park","doi":"10.7762/cnr.2025.14.4.241","DOIUrl":"10.7762/cnr.2025.14.4.241","url":null,"abstract":"Pressure injuries are common complications in patients with limited mobility, particularly those who are bedridden. These wounds not only cause pain and reduce quality of life but also lead to prolonged hospitalization, increased risk of infection, and higher healthcare costs. Among the various contributing factors, malnutrition plays a crucial role by impairing collagen synthesis, weakening immune function, and delaying tissue repair. Adequate nutritional support-particularly sufficient protein and energy intake-is therefore an essential component of comprehensive pressure injury management. We present the case of a paraplegic patient who developed a vulvar pressure injury. A structured, stepwise nutritional intervention was implemented, including adjustment of meal composition based on appetite, supplementation with high-protein oral nutritional supplements, vitamins and minerals, and the use of probiotics to manage diarrhea. As a result, the patient's daily protein intake increased from less than 10 g to 80-90 g, accompanied by progressive wound improvement. Serial clinical assessments showed reduced slough, increased granulation tissue formation, and epithelialization. This case highlights the vital role of individualized nutritional management within a multidisciplinary approach to pressure injury care. Stepwise nutritional intervention, tailored to the patient's tolerance and clinical status, contributed significantly to wound healing. Nutritional optimization should be considered an integral component of effective pressure injury treatment strategies.","PeriodicalId":72617,"journal":{"name":"Clinical nutrition research","volume":"14 4","pages":"241-246"},"PeriodicalIF":0.0,"publicationDate":"2025-10-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12629406/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145566351","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0