{"title":"用口服营养补充剂代替不进食对老年人营养状况和身体机能的影响。","authors":"Jiyeon Lee, Seong Ah Cho, Seoyoon Choi, Eunbi Han, Hyeri Shin, Yoo Kyoung Park","doi":"10.7762/cnr.2025.14.3.191","DOIUrl":null,"url":null,"abstract":"<p><p>This study evaluated the effects of replacing skipped meals with oral nutritional supplements (ONS) on the nutritional status and functional health of older adults. A total of 29 participants aged ≥ 65 years who regularly skipped at least one meal per day were included in this single-arm study. For 8 weeks, participants consumed two packs of ONS daily (150 mL each, providing 400 kcal and 18 g of protein) as a substitute for skipped meals. Nutritional status, nutrient intake, body composition, and physical function were assessed before and after the intervention. The Nutrition Quotient for the Elderly score significantly increased from 58.97 to 63.62 (p = 0.014). Total nutrient intake, including ONS, significantly improved compared with baseline (p < 0.01). Body weight and body mass index increased significantly from 58.87 to 59.47 kg (p = 0.028) and from 23.9 to 24.18 kg/m<sup>2</sup> (p = 0.016), respectively. Calf circumference decreased significantly from 34.1 to 33.39 cm (p = 0.010). Physical function, assessed using the Short Physical Performance Battery, showed significant improvement (p = 0.003). In conclusion, replacing skipped meals with ONS may enhance nutritional status and support functional health in older adults.</p><p><strong>Trial registration: </strong>Clinical Research Information Service Identifier: KCT0010184.</p>","PeriodicalId":72617,"journal":{"name":"Clinical nutrition research","volume":"14 3","pages":"191-203"},"PeriodicalIF":0.0000,"publicationDate":"2025-07-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12321495/pdf/","citationCount":"0","resultStr":"{\"title\":\"Effects of Replacing Skipped Meals With Oral Nutritional Supplement on Nutritional Status and Physical Function in Older Adults.\",\"authors\":\"Jiyeon Lee, Seong Ah Cho, Seoyoon Choi, Eunbi Han, Hyeri Shin, Yoo Kyoung Park\",\"doi\":\"10.7762/cnr.2025.14.3.191\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><p>This study evaluated the effects of replacing skipped meals with oral nutritional supplements (ONS) on the nutritional status and functional health of older adults. A total of 29 participants aged ≥ 65 years who regularly skipped at least one meal per day were included in this single-arm study. For 8 weeks, participants consumed two packs of ONS daily (150 mL each, providing 400 kcal and 18 g of protein) as a substitute for skipped meals. Nutritional status, nutrient intake, body composition, and physical function were assessed before and after the intervention. The Nutrition Quotient for the Elderly score significantly increased from 58.97 to 63.62 (p = 0.014). Total nutrient intake, including ONS, significantly improved compared with baseline (p < 0.01). Body weight and body mass index increased significantly from 58.87 to 59.47 kg (p = 0.028) and from 23.9 to 24.18 kg/m<sup>2</sup> (p = 0.016), respectively. Calf circumference decreased significantly from 34.1 to 33.39 cm (p = 0.010). Physical function, assessed using the Short Physical Performance Battery, showed significant improvement (p = 0.003). In conclusion, replacing skipped meals with ONS may enhance nutritional status and support functional health in older adults.</p><p><strong>Trial registration: </strong>Clinical Research Information Service Identifier: KCT0010184.</p>\",\"PeriodicalId\":72617,\"journal\":{\"name\":\"Clinical nutrition research\",\"volume\":\"14 3\",\"pages\":\"191-203\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2025-07-29\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12321495/pdf/\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Clinical nutrition research\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.7762/cnr.2025.14.3.191\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"2025/7/1 0:00:00\",\"PubModel\":\"eCollection\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Clinical nutrition research","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.7762/cnr.2025.14.3.191","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2025/7/1 0:00:00","PubModel":"eCollection","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 0
摘要
本研究评估了用口服营养补充剂(ONS)代替不吃正餐对老年人营养状况和功能健康的影响。这项单臂研究共纳入29名年龄≥65岁、每天至少不吃一顿饭的参与者。在8周的时间里,参与者每天摄入两包ONS(每份150毫升,提供400千卡热量和18克蛋白质)作为不吃饭的替代品。评估干预前后的营养状况、营养摄入、身体成分和身体功能。老年人营养商数得分由58.97提高到63.62,差异有统计学意义(p = 0.014)。与基线相比,包括ONS在内的总营养摄入量显著提高(p < 0.01)。体重和体质量指数分别从58.87增加到59.47 kg (p = 0.028)和23.9增加到24.18 kg/m2 (p = 0.016)。小腿围由34.1 cm显著降低至33.39 cm (p = 0.010)。使用短物理性能电池评估的身体功能显示出显着改善(p = 0.003)。总之,用ONS代替不吃的饭可以改善老年人的营养状况并支持功能健康。试验注册:临床研究信息服务标识:KCT0010184。
Effects of Replacing Skipped Meals With Oral Nutritional Supplement on Nutritional Status and Physical Function in Older Adults.
This study evaluated the effects of replacing skipped meals with oral nutritional supplements (ONS) on the nutritional status and functional health of older adults. A total of 29 participants aged ≥ 65 years who regularly skipped at least one meal per day were included in this single-arm study. For 8 weeks, participants consumed two packs of ONS daily (150 mL each, providing 400 kcal and 18 g of protein) as a substitute for skipped meals. Nutritional status, nutrient intake, body composition, and physical function were assessed before and after the intervention. The Nutrition Quotient for the Elderly score significantly increased from 58.97 to 63.62 (p = 0.014). Total nutrient intake, including ONS, significantly improved compared with baseline (p < 0.01). Body weight and body mass index increased significantly from 58.87 to 59.47 kg (p = 0.028) and from 23.9 to 24.18 kg/m2 (p = 0.016), respectively. Calf circumference decreased significantly from 34.1 to 33.39 cm (p = 0.010). Physical function, assessed using the Short Physical Performance Battery, showed significant improvement (p = 0.003). In conclusion, replacing skipped meals with ONS may enhance nutritional status and support functional health in older adults.
Trial registration: Clinical Research Information Service Identifier: KCT0010184.