Clinical nutrition research最新文献_第9页

Evaluation of Serum Omentin-1, Vaspin, Leptin, Adiponectin Levels in Obese/Overweight Children and Their Relationship With Non-Alcoholic Fatty Liver Disease. 肥胖/超重儿童血清Omentin-1、Vaspin、Leptin、脂联素水平的评价及其与非酒精性脂肪肝的关系

Clinical nutrition research Pub Date : 2022-07-25 eCollection Date: 2022-07-01 DOI: 10.7762/cnr.2022.11.3.194

Esra Akyüz Özkan, Allahverdi Sadigov, Osman Öztürk

{"title":"Evaluation of Serum Omentin-1, Vaspin, Leptin, Adiponectin Levels in Obese/Overweight Children and Their Relationship With Non-Alcoholic Fatty Liver Disease.","authors":"Esra Akyüz Özkan, Allahverdi Sadigov, Osman Öztürk","doi":"10.7762/cnr.2022.11.3.194","DOIUrl":"https://doi.org/10.7762/cnr.2022.11.3.194","url":null,"abstract":"To investigate adipokines (vaspin, omentin-1, adiponectin and leptin) and their correlation with hepatosteatosis degree in obese/overweight (O/O) children. We analyzed adipokine levels of 81 children (49 O/O, [body mass index (BMI) > 95th] and 32 non-obese (BMI = 5-85th) admitted to the pediatric outpatient clinic. Serum triglyceride, glucose, low density lipoprotein-cholesterol, total cholesterol, high density lipoprotein-cholesterol, alanine aminotransferase, aspartate aminotransferase (AST), insulin, HbA1c levels and leptin, omentin-1, vaspin, adiponectin levels were studied. O/O children with hepatosteatosis were divided into grades 1, 2 and 3 according to the degree of hepatosteatosis determined by ultrasonography. While AST (p = 0.001), triglyceride (p = 0.006), BMI percentile (p = 0.000), HOMA index (p = 0.002), systolic blood pressure (p = 0.02), leptin (p = 0.001), omentin-1 (p = 0.001), adiponectin (p = 0.001) levels were higher, vaspin level was lower (p = 0.008) in the (O/O) group compared to the controls. There was a positive correlation between HDL and vaspin, and a negative correlation between HDL and omentin-1 in the O/O group. Also it was observed that as the degree of hepatosteotosis increased, leptin (p = 0.004), omentin-1 (p = 0.001) levels were increased. There was no significant change in vaspin level (p = 0.128). The high levels of omentin-1, leptin and adiponectin have an association with the development of hepatosteatosis in O/O children.","PeriodicalId":72617,"journal":{"name":"Clinical nutrition research","volume":"11 3","pages":"194-203"},"PeriodicalIF":0.0,"publicationDate":"2022-07-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/ce/c3/cnr-11-194.PMC9348910.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40616577","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 4

Positive Association Between Nutrient Adequacy and Waist Circumference: Results of a Cross-Sectional Study. 营养充足与腰围正相关:一项横断面研究的结果。

Clinical nutrition research Pub Date : 2022-07-25 eCollection Date: 2022-07-01 DOI: 10.7762/cnr.2022.11.3.204

Aliyu T Jibril, Parivash Ghorbaninejad, Fatemeh Sheikhhossein, Sakineh Shab-Bidar

{"title":"Positive Association Between Nutrient Adequacy and Waist Circumference: Results of a Cross-Sectional Study.","authors":"Aliyu T Jibril, Parivash Ghorbaninejad, Fatemeh Sheikhhossein, Sakineh Shab-Bidar","doi":"10.7762/cnr.2022.11.3.204","DOIUrl":"https://doi.org/10.7762/cnr.2022.11.3.204","url":null,"abstract":"Metabolic syndrome (MetS) is a multifactorial disease with its exact causes not completely clear. Micronutrients such as vitamin A, vitamin D, zinc, and magnesium have been associated with MetS components. Our objective was to investigate the association of nutrient adequacy (NA) with MetS components. The present cross-sectional study consisted of 850 adults between 18-59 years from Tehran, Iran. Dietary intake, socio-demographic data, medical history, and anthropometric indices were collected by trained personnel. NA was calculated as the mean intake ratio to the recommended amount of 16 micronutrients. MetS were defined by the consensus of National Cholesterol Education Program-Adult Treatment Panel III criteria. The association between NA and MetS was examined using linear regression analyses after controlling potential confounders. More participants in the highest quartile were obese in terms of general obesity (p = 0004) and abdominal obesity (p = 0.003) compared with subjects in the least quartile. A significant positive correlation was found between waist circumference (WC) and NA even after controlling for all potential confounders (p < 0.001). NA was positively associated with WC among adults living in Tehran.","PeriodicalId":72617,"journal":{"name":"Clinical nutrition research","volume":"11 3","pages":"204-213"},"PeriodicalIF":0.0,"publicationDate":"2022-07-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/76/29/cnr-11-204.PMC9348912.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40617022","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The Effect of Nutrition Education Using MyPlate on Lipid Profiles, Glycemic Indices, and Inflammatory Markers in Diabetic Patients. 利用我的餐盘进行营养教育对糖尿病患者血脂、血糖指数和炎症标志物的影响

Clinical nutrition research Pub Date : 2022-07-25 eCollection Date: 2022-07-01 DOI: 10.7762/cnr.2022.11.3.171

Mehrnoosh Zakerkish, Shima Shahmoradi, Fatemeh Haidari, Seyed Mahmoud Latifi, Majid Mohammadshahi

{"title":"The Effect of Nutrition Education Using MyPlate on Lipid Profiles, Glycemic Indices, and Inflammatory Markers in Diabetic Patients.","authors":"Mehrnoosh Zakerkish, Shima Shahmoradi, Fatemeh Haidari, Seyed Mahmoud Latifi, Majid Mohammadshahi","doi":"10.7762/cnr.2022.11.3.171","DOIUrl":"https://doi.org/10.7762/cnr.2022.11.3.171","url":null,"abstract":"As a result of a nutrition transition, chronic diseases, including diabetes, have increased in Iran. Nutrition education is a cost-effective method for modifying diet and controlling diabetes. This study aimed to examine the effect of nutrition education using MyPlate recommendations on glycemic and lipid profiles and inflammatory markers in Iranian adults diagnosed with type 2 diabetes. A 12-week randomized clinical trial was conducted on 44 adults aged 30-50 years from Ahvaz, Iran. The participants were divided into education and control groups. The education participants were taught the MyPlate recommendations. Serum levels of fasting blood sugar (FBS), hemoglobin A1c (HbA1c), lipid profiles, and inflammatory markers, including high sensitivity C-reactive protein (hs-CRP), tumor necrosis factor-α, and adiponectin, were measured at the baseline and the end of the study. The results showed that serum levels of FBS (p = 0.014) and HbA1c (p < 0.001) decreased significantly in the education group at the end of the study. The serum level of low-density lipoprotein in the education group declined significantly at the end of the study (p = 0.043). Furthermore, the serum level of hs-CRP (p = 0.005) declined significantly while the level of adiponectin (p = 0.035) increased in the education group at the end of the study. The evidence of this study showed that nutrition education using MyPlate recommendations is an effective method for controlling diabetes complications. A longitudinal analysis with a larger sample size is recommended to confirm the evidence of this study.Trial registration: Iranian Registry of Clinical Trials Identifier: IRCT2015031921443N2.","PeriodicalId":72617,"journal":{"name":"Clinical nutrition research","volume":"11 3","pages":"171-182"},"PeriodicalIF":0.0,"publicationDate":"2022-07-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/f7/30/cnr-11-171.PMC9348908.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40616575","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Comparison of Cerebral Cortex Transcriptome Profiles in Ischemic Stroke and Alzheimer's Disease Models. 缺血性卒中和阿尔茨海默病模型中大脑皮层转录组谱的比较

Clinical nutrition research Pub Date : 2022-07-25 eCollection Date: 2022-07-01 DOI: 10.7762/cnr.2022.11.3.159

Juhyun Song

{"title":"Comparison of Cerebral Cortex Transcriptome Profiles in Ischemic Stroke and Alzheimer's Disease Models.","authors":"Juhyun Song","doi":"10.7762/cnr.2022.11.3.159","DOIUrl":"https://doi.org/10.7762/cnr.2022.11.3.159","url":null,"abstract":"Ischemic stroke and Alzheimer's disease (AD) are representative geriatric diseases with a rapidly increasing prevalence worldwide. Recent studies have reported an association between ischemic stroke neuropathology and AD neuropathology. Ischemic stroke shares some similar characteristics with AD, such as glia activation-induced neuroinflammation, amyloid beta accumulation, and neuronal cell loss, as well as some common risk factors with AD progression. Although there are considerable similarities in neuropathology between ischemic stroke and AD, no studies have ever compared specific genetic changes of brain cortex between ischemic stroke and AD. Therefore, in this study, I compared the cerebral cortex transcriptome profile of 5xFAD mice, an AD mouse model, with those of middle cerebral artery occlusion (MCAO) mice, an ischemic stroke mouse model. The data showed that the expression of many genes with important functional implications in MCAO mouse brain cortex were related to synaptic dysfunction and neuronal cell death in 5xFAD mouse model. In addition, changes in various protein-coding RNAs involved in synaptic plasticity, amyloid beta accumulation, neurogenesis, neuronal differentiation, glial activation, inflammation and neurite outgrowth were observed. The findings could serve as an important basis for further studies to elucidate the pathophysiology of AD in patients with ischemic stroke.","PeriodicalId":72617,"journal":{"name":"Clinical nutrition research","volume":"11 3","pages":"159-170"},"PeriodicalIF":0.0,"publicationDate":"2022-07-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/47/e5/cnr-11-159.PMC9348914.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40697008","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

Effects of Artichoke Supplementation on Liver Enzymes: A Systematic Review and Meta-Analysis of Randomized Controlled Trials. 补充洋蓟对肝酶的影响:随机对照试验的系统回顾和荟萃分析。

Clinical nutrition research Pub Date : 2022-07-25 eCollection Date: 2022-07-01 DOI: 10.7762/cnr.2022.11.3.228

Mohammad Reza Amini, Fatemeh Sheikhhossein, Alireza Talebyan, Elham Bazshahi, Farhang Djafari, Azita Hekmatdoost

{"title":"Effects of Artichoke Supplementation on Liver Enzymes: A Systematic Review and Meta-Analysis of Randomized Controlled Trials.","authors":"Mohammad Reza Amini, Fatemeh Sheikhhossein, Alireza Talebyan, Elham Bazshahi, Farhang Djafari, Azita Hekmatdoost","doi":"10.7762/cnr.2022.11.3.228","DOIUrl":"https://doi.org/10.7762/cnr.2022.11.3.228","url":null,"abstract":"Studies examining the effect of artichoke on liver enzymes have reported inconsistent results. This systematic review and meta-analysis aimed to assess the effects of artichoke administration on the liver enzymes. PubMed, Embase, the Cochrane Library, and Scopus databases were searched for articles published up to January 2022. Standardized mean difference (Hedges' g) were analyzed using a random-effects model. Heterogeneity, publication bias, and sensitivity analysis were assessed for the liver enzymes. Pooled analysis of seven randomized controlled trials (RCTs) suggested that the artichoke administration has an effect on both alanine aminotransferase (ALT) (Hedges' g, -1.08; 95% confidence interval [CI], -1.76 to -0.40; p = 0.002), and aspartate aminotransferase (AST) (Hedges' g, -1.02; 95% CI, -1.76 to -0.28; p = 0.007). Greater effects on ALT were detected in trials that lasted ≤8 weeks. Also, greater effects on AST were detected in trials using > 500 mg artichoke. Overall, this meta-analysis demonstrated artichoke supplementation decreased ALT and AST.","PeriodicalId":72617,"journal":{"name":"Clinical nutrition research","volume":"11 3","pages":"228-239"},"PeriodicalIF":0.0,"publicationDate":"2022-07-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/cc/9c/cnr-11-228.PMC9348909.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40616576","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The Effect of Walnut (Juglans regia) Leaf Extract on Glycemic Control and Lipid Profile in Patients With Type 2 Diabetes Mellitus: A Systematic Review and Meta-Analysis of Randomized Clinical Trials 核桃叶提取物对2型糖尿病患者血糖控制和血脂水平的影响：随机临床试验的系统评价和荟萃分析

Clinical nutrition research Pub Date : 2022-04-01 DOI: 10.7762/cnr.2022.11.2.120

A. Mirzababaei, M. Daneshvar, Faezeh Abaj, E. Daneshzad, Dorsa Hosseininasab, Cain C. T. Clark, K. Mirzaei

{"title":"The Effect of Walnut (Juglans regia) Leaf Extract on Glycemic Control and Lipid Profile in Patients With Type 2 Diabetes Mellitus: A Systematic Review and Meta-Analysis of Randomized Clinical Trials","authors":"A. Mirzababaei, M. Daneshvar, Faezeh Abaj, E. Daneshzad, Dorsa Hosseininasab, Cain C. T. Clark, K. Mirzaei","doi":"10.7762/cnr.2022.11.2.120","DOIUrl":"https://doi.org/10.7762/cnr.2022.11.2.120","url":null,"abstract":"Numerous clinical trials have examined the beneficial effects of Juglans regia leaf extract (JRLE) in patients with type 2 diabetes mellitus (T2DM); however, the results of these studies are inconsistent. Therefore, we conducted the current systematic review and meta-analysis to evaluate the effect of JRLE on glycemic control and lipid profile in T2DM patients. We searched online databases including PubMed, Scopus, EMBASE, and Web of Science for randomized controlled clinical trials that examined the effect of JRLE on glycemic and lipid indices in T2DM patients. Data were pooled using both fixed and random-effect models and weighted mean difference (WMD) was considered as the overall effect size. Of the total records, 4 eligible studies, with a total sample size of 195 subjects, were included. The meta-analysis revealed that JRLE supplementation significantly reduces fasting blood glucose (WMD, −18.04; 95% confidence interval [CI], −32.88 mg/dL, −3.21 mg/dL; p = 0.017) and significantly increases fasting insulin level (WMD, 1.93; 95% CI, 0.40 U/L, 3.45 U/L; p = 0.014). Although the overall effect of JRLE supplementation on hemoglobin A1c was not significant, a significant reduction was seen in studies with an intervention duration of > 8 weeks (WMD, −0.64; 95% CI, −1.16%, −0.11%; p = 0.018). Moreover, we also found no significant change in lipid parameters. Our findings revealed a beneficial effect of JRLE supplementation on glycemic indices in T2DM patients, but no significant improvement was found for lipid profile parameters.","PeriodicalId":72617,"journal":{"name":"Clinical nutrition research","volume":"11 1","pages":"120 - 132"},"PeriodicalIF":0.0,"publicationDate":"2022-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42248375","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

Effects of the Enhanced Recovery After Surgery (ERAS) Program for Colorectal Cancer Patients Undergoing Laparoscopic Surgery 腹腔镜手术对结直肠癌患者术后恢复的影响

Clinical nutrition research Pub Date : 2022-04-01 DOI: 10.7762/cnr.2022.11.2.75

Jeongwon Yeom, H. Lim

{"title":"Effects of the Enhanced Recovery After Surgery (ERAS) Program for Colorectal Cancer Patients Undergoing Laparoscopic Surgery","authors":"Jeongwon Yeom, H. Lim","doi":"10.7762/cnr.2022.11.2.75","DOIUrl":"https://doi.org/10.7762/cnr.2022.11.2.75","url":null,"abstract":"This study sought to investigate the effects of the enhanced recovery after surgery (ERAS) program on postoperative recovery and nutritional status in patients with colorectal cancer undergoing laparoscopic surgery. A total of 37 patients were included: 19 in the experimental group and 18 in the control group. The experimental group was supplemented with carbohydrate drinks before and after surgery, and the control group was maintained with fasting and water intake in the traditional method. Both care management and nutrition education were implemented for both groups. Patients were evaluated for physical condition, clinical indicators, blood tests, pain, length of stay, nutritional status, and nutrient intake. Use of the ERAS program for the experimental group resulted in shorter length of stay (p = 0.006), less pain (p < 0.001), and a lower rate of malnutrition (p = 0.014) compared with controls. In conclusion, carbohydrate drinks provide great advantages by reducing discomfort, such as pain or thirst, during fasting in patients after colon cancer surgery, helping patients to eat comfortably and actively, minimizing insulin resistance, maintaining nitrogen balance, and reducing infection and anastomosis leakage. For use of ERAS as a standardized program, repeated and expanded research is needed, and a Korean-style ERAS should be prepared by using this approach for various diseases.","PeriodicalId":72617,"journal":{"name":"Clinical nutrition research","volume":"11 1","pages":"75 - 83"},"PeriodicalIF":0.0,"publicationDate":"2022-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44068468","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 3

The Association Between Dietary Energy Density and Musculoskeletal Pain in Adult Men and Women 膳食能量密度与成年男性和女性肌肉骨骼疼痛的关系

Clinical nutrition research Pub Date : 2022-04-01 DOI: 10.7762/cnr.2022.11.2.110

Niki Bahrampour, Niloufar Rasaei, Fatemeh Gholami, C. Clark

{"title":"The Association Between Dietary Energy Density and Musculoskeletal Pain in Adult Men and Women","authors":"Niki Bahrampour, Niloufar Rasaei, Fatemeh Gholami, C. Clark","doi":"10.7762/cnr.2022.11.2.110","DOIUrl":"https://doi.org/10.7762/cnr.2022.11.2.110","url":null,"abstract":"Musculoskeletal pains (MPs), defined as persistent or recurrent pain, is a complex health problem. High overall calorie and fat intake have been related to obesity and MPs. Dietary energy density (DED), defined as energy content of food and beverages (in kcal) per unit total weight, has been associated with chronic muscle, cartilage, bone damage and pain. Thus, the purpose of this study is to investigate the association between DED and MPs in adult men and women. A total of 175 men and women (> 18 years) with MP participated in the study. A validated short form physical activity (PA) questionnaire, demographic, and McGill Pain Questionnaire were used. Anthropometric measurements were evaluated via standard protocols. Furthermore, a seven-day 24-hour recall of diet was used to determine the dietary intake. Total DED was calculated and divided into quartiles. Linear regression was used to discern the association between DED and MPs in adults. Participants assigned in the highest category of DED were characterized by lower intake of potassium, magnesium, vitamin C, folate, and fiber. However, results showed displayed higher intake of sodium, vitamin E, vitamin B3, fat, protein, cholesterol, saturated fatty acids, monounsaturated fatty acids, and polyunsaturated fatty acids (p < 0.001). Finally, after adjustment for confounders such as age, gender, PA, body mass index, waist circumference, education, job, marital status, history of some chronic diseases and vitamin C supplementation, a significant positive association was detected between DED and pain intensity. There was no significant association between DED and pain frequency in all models.","PeriodicalId":72617,"journal":{"name":"Clinical nutrition research","volume":"11 1","pages":"110 - 119"},"PeriodicalIF":0.0,"publicationDate":"2022-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44157760","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Nutrition Management Through Nitrogen Balance Analysis in Patient With Short Bowel Syndrome 通过氮平衡分析短肠综合征患者的营养管理

Clinical nutrition research Pub Date : 2022-04-01 DOI: 10.7762/cnr.2022.11.2.146

A-Reum Kim, Sung-heum Sim, Jeeyeon Kim, J. Hwang, Junghyun Park, Jehoon Lee, J. Cheon

引用次数: 0

Musculoskeletal Health of the Adults Over 50 Years of Age in Relation to Antioxidant Vitamin Intakes 50岁以上成人肌肉骨骼健康与抗氧化维生素摄入的关系

Clinical nutrition research Pub Date : 2022-04-01 DOI: 10.7762/cnr.2022.11.2.84

N. Kim, Yeji Kang, Y. Choi, Yunhwan Lee, Seok-Jun Park, H. Park, M. Kwon, Yoon-Sok Chung, Y. Park

{"title":"Musculoskeletal Health of the Adults Over 50 Years of Age in Relation to Antioxidant Vitamin Intakes","authors":"N. Kim, Yeji Kang, Y. Choi, Yunhwan Lee, Seok-Jun Park, H. Park, M. Kwon, Yoon-Sok Chung, Y. Park","doi":"10.7762/cnr.2022.11.2.84","DOIUrl":"https://doi.org/10.7762/cnr.2022.11.2.84","url":null,"abstract":"As the proportion of the elderly population increases rapidly, interest in musculoskeletal health is also emerging. Here, we investigated how antioxidant vitamin intake and musculoskeletal health are related. Adults aged 50 to 80 years with a body mass index (BMI) of 18.5 to 27.0 kg/m2 were included. Bone mineral density (BMD), lean mass (LM), appendicular skeletal muscle mass index (ASMI) were measured using dual-energy X-ray absorptiometry (DXA), and the grip strength and knee extension using hand dynamometer. Nutrient intakes were measured using a 24-hour recall questionnaire. A total of 153 adults (44 men and 109 women) participated in this study. A partial correlation analysis showed a significant positive relationship between vitamin E and BMD and between vitamin C and LM/Height. Participants were classified into three groups according to whether their vitamin E and C intake met the recommended intake for Dietary Reference Intakes for Koreans (KDRIs). The prevalence of having low T-score (< −1.0) and low ASMI (< 7.0 for men and < 5.4 for women) was 51.3% and 15.4% in the group with vitamins C and E intakes below KDRIs. After adjusting for sex, smoking status and energy, protein, vitamin D, and calcium intake, the group with vitamins C and E both below the KDRIs displayed a significantly lower BMD at all test sites and LM/Height compared with vitamin C and/or E intake above the KDRIs groups. We conclude that sufficient intake of vitamin E and C is important for maintaining BMD and lean mass in Korean adults over 50 years of age.","PeriodicalId":72617,"journal":{"name":"Clinical nutrition research","volume":"11 1","pages":"84 - 97"},"PeriodicalIF":0.0,"publicationDate":"2022-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48469416","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1