Acupuncture in Medicine最新文献

{"title":"Acupuncture for erectile dysfunction in multiple system atrophy: a case report.","authors":"L Zhang, Pan ZhongQiang, Y Zou","doi":"10.1177/09645284261421947","DOIUrl":"10.1177/09645284261421947","url":null,"abstract":"","PeriodicalId":7257,"journal":{"name":"Acupuncture in Medicine","volume":" ","pages":"236-238"},"PeriodicalIF":2.7,"publicationDate":"2026-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146199902","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Electroacupuncture mitigates lung injury, increases endogenous antioxidant levels and modulates Nrf2 signaling in a rat model of chronic obstructive pulmonary disease.","authors":"Yange Tian, Lanxi Zhang, Peng Zhao, Xuefang Liu, Fanli Jin, Yang Liu, Jiansheng Li","doi":"10.1177/09645284261424261","DOIUrl":"10.1177/09645284261424261","url":null,"abstract":"<p><strong>Background: </strong>Electroacupuncture (EA) has shown efficacy in the treatment of chronic obstructive pulmonary disease (COPD), but the underlying mechanism of action remains unclear. Oxidative stress is a main pathological process in COPD. This aim of this study was to explore the anti-oxidant effect of EA in a COPD rat model.</p><p><strong>Methods: </strong>Rats were divided into control, model, EA, sham acupuncture (SA) and N-acetylcysteine (NAC) groups. All rats except those in the control group were exposed to cigarette smoke combined with repeated bacterial infection to induce a COPD rat model. Rats in the EA group received EA at GV14 and bilateral BL13/BL23 for a further 8 weeks, while rats in SA group were given manual acupuncture at sites 5 mm from the traditional acupuncture point locations (without electrical stimulation) as a negative control. NAC (54 mg/kg/d) was used in the NAC group as a positive control. Lung function was assessed by whole body plethysmography, and tissue structure was assessed by histology. mRNA and protein levels of oxidative indicators and nuclear factor E2-related factor (Nrf2) signaling were measured by qPCR and immunohistochemistry or Western blotting, respectively.</p><p><strong>Results: </strong>After EA treatment, lung function and pathological features were improved. Total antioxidant capacity (T-AOC) and total superoxide dismutase (T-SOD) in serum, as well as SOD1 and heme oxygenase (HO)-1 in lung tissue, were increased, while markers of oxidative stress-lipid peroxidation (LPO) and malonaldehyde activity (MDA)-were decreased. Nrf2 protein in the nucleus of lung tissue, as well as HO-1 and γ-glutamylcysteine synthetase (γ-GCS) mRNA and protein, were improved. NAC, as an antioxidant, was better than EA at increasing the expression of HO-1 protein and γ-GCS mRNA.</p><p><strong>Conclusions: </strong>EA was beneficial for the treatment of COPD in this rat model and exerted antioxidant effects via mechanisms potentially related to Nrf2 signaling.</p>","PeriodicalId":7257,"journal":{"name":"Acupuncture in Medicine","volume":" ","pages":"210-221"},"PeriodicalIF":2.7,"publicationDate":"2026-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147466627","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effects of electroacupuncture on perioperative neurocognitive impairment and gut-associated Th17/Treg balance in aged rats.","authors":"Fen Wang, Xizi Qiu, Qian Xu, Libing Huang, Juan Zhu, Rong Zou, Shanshan Tan, Meilu Yu, Saiya Zhang, Tianhao Li, Weiqian Tian","doi":"10.1177/09645284261462568","DOIUrl":"https://doi.org/10.1177/09645284261462568","url":null,"abstract":"<p><strong>Background: </strong>Perioperative neurocognitive disorder (PND) occurs most frequently in elderly populations undergoing surgery and anesthesia. Evidence suggests that gut-initiated helper T (Th)17/regulatory T (Treg) cell immune responses are involved in the pathogenesis of neurocognitive disorders, and electroacupuncture (EA) has been shown to be effective at regulating Th17/Treg cell balance and ameliorating cognitive dysfunction. The aim of this study was to investigate whether EA ameliorates PND via the regulation of gut-initiated Th17/Treg immune balance in a rat model.</p><p><strong>Methods: </strong>Exploratory laparotomy was performed in aged rats to establish a PND model, and EA at ST36 and ST37 was administered daily for 5 days before surgery. Neurocognitive function was evaluated using the Morris water maze test. Colonic mucosa and hippocampal neurons were observed under hematoxylin and eosin (H&E) staining. Ionized calcium-binding adapter molecule (Iba)1, a hippocampal microglia marker, was observed by immunohistochemistry. Proportions of Th17 and Treg cells in mesenteric lymph nodes (MLNs) and blood were examined by flow cytometry. Western blotting was used to detect the protein expression of retinoid-related orphan receptor (ROR)γt and forkhead box (Fox)p3 in the colon and hippocampus. Levels of interleukin (IL)-17A and IL-10 in the blood and hippocampus were examined by enzyme-linked immunosorbent assay.</p><p><strong>Results: </strong>EA pretreatment improved surgery-induced neurocognitive impairment. Meanwhile, EA inhibited colonic mucosal injury, neuronal damage and microglial activation in PND rats. EA also decreased Th17 cells in the MLN and blood, RORγt in the colon and hippocampus, and IL-17A in the blood and hippocampus of PND rats. EA reversed downregulation of Treg cells in the MLN, Foxp3 in the colon and hippocampus, and IL-10 in the blood and hippocampus of PND rats.</p><p><strong>Conclusion: </strong>Collectively, the results suggest that the therapeutic benefits of EA pretreatment in this PND rat model may be attributable to the regulation of gut-associated Th17/Treg immune balance.</p>","PeriodicalId":7257,"journal":{"name":"Acupuncture in Medicine","volume":" ","pages":"9645284261462568"},"PeriodicalIF":2.7,"publicationDate":"2026-07-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148597613","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Acupuncture for triangular fibrocartilage complex injury: A case report.","authors":"Liqun Yang","doi":"10.1177/09645284261462569","DOIUrl":"https://doi.org/10.1177/09645284261462569","url":null,"abstract":"","PeriodicalId":7257,"journal":{"name":"Acupuncture in Medicine","volume":" ","pages":"9645284261462569"},"PeriodicalIF":2.7,"publicationDate":"2026-07-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148560373","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Electroacupuncture ameliorates disuse muscular atrophy and inhibits the NLRP3 inflammasome and SIRT1 through miR-133a in a mouse model.","authors":"Xing Cai, Yalian Zhang, Zhong Yang, Yuan Jiang, Bin Shu","doi":"10.1177/09645284261462570","DOIUrl":"https://doi.org/10.1177/09645284261462570","url":null,"abstract":"<p><strong>Objective: </strong>The aim of this study was to explore the potential role of microRNA (miR)-133a, the nucleotide-binding oligomerization domain, leucine-rich repeat family pyrin domain-containing 3 (NLRP3) inflammasome and Sirtuin1 (SIRT1) in the effects of electroacupuncture (EA) on disuse muscular atrophy in mice.</p><p><strong>Methods: </strong>C2C12 cells were analyzed for protein expression of NLRP3, SIRT1, myogenin (MyoG) and myosin heavy chain protein (MyHC) after being transfected with a miR-133a-1 mimetic or miR-133a-3p inhibitor. Disuse muscular atrophy was induced in mice by tail suspension, and the mice either remained untreated (DA group) or received EA (frequency 20 Hz, intensity 1 mA, 15 min per day). The morphology of skeletal muscle was measured by muscle/body weight ratios, muscle fiber cross-sectional area (CSA) and expression of Atrogin-1 and Muscle RING finger-1 (MuRF1). miR-133a, NLRP3, apoptosis-associated speck-like protein (ASC), caspase-1 and SIRT1 were detected sequentially. Differentiation of skeletal muscle was examined by measurement of MyoG and MyHC.</p><p><strong>Results: </strong>In our in vitro experiments, overexpression of miR-133a downregulated the expression of NLRP3 and SIRT1, and upregulated the expression of MyoG and MyHC. In our in vivo experiments, EA effectively ameliorated muscle wet weight and fiber CSA in the mouse model of disuse muscular atrophy, and decreased Atrogin-1 and MuRF1. EA also significantly increased the expression of miR-133a, inhibited the expression of NLRP3, ASC, caspase-1 and SIRT1, and increased the expression of MyoG and MyHC.</p><p><strong>Conclusions: </strong>These results indicate that EA-induced reductions of disuse muscular atrophy may be related to miR-133a. First, miR-133a may inhibit NLRP3 inflammasome activation to reduce muscle loss. Second, miR-133a may regulate SIRT1 expression to induce skeletal muscle differentiation and potentially promote muscle tissue recovery.</p>","PeriodicalId":7257,"journal":{"name":"Acupuncture in Medicine","volume":" ","pages":"9645284261462570"},"PeriodicalIF":2.7,"publicationDate":"2026-07-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148395520","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Precision acupuncture: Moving from art to evidence-based science.","authors":"Wen-Chao Tang, Da-Eun Yoon, Younbyoung Chae","doi":"10.1177/09645284261458401","DOIUrl":"https://doi.org/10.1177/09645284261458401","url":null,"abstract":"","PeriodicalId":7257,"journal":{"name":"Acupuncture in Medicine","volume":" ","pages":"9645284261458401"},"PeriodicalIF":2.7,"publicationDate":"2026-07-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148381338","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Attitudes and expectations towards acupuncture for primary dysmenorrhoea: Findings from a cross-sectional survey in Australia.","authors":"Weiting Liu, Amanda Towell-Barnard, Khui Hung Lee, Timothy Leen Kang","doi":"10.1177/09645284261458839","DOIUrl":"https://doi.org/10.1177/09645284261458839","url":null,"abstract":"<p><strong>Objective: </strong>To describe attitudes towards acupuncture and expectations regarding potential treatment outcomes among women with self-reported primary dysmenorrhoea (PD) residing in Australia.</p><p><strong>Methods: </strong>A cross-sectional, descriptive online survey was conducted to assess attitudes and treatment expectancy using an adapted version of previously published complementary and alternative medicine (CAM) attitude scale and a validated acupuncture expectancy scale (AES). Data were analysed descriptively, with exploratory analysis conducted to support the interpretation of response patterns. Ethical approval was obtained from the Edith Cowan University Human Research Ethics Committee (2023-04471-LIU) and participants provided electronic informed consent.</p><p><strong>Results: </strong>A total of 247 responses were received. Participants were mainly aged 25-30 years and largely from Western Australia. Many reported having experienced PD for more than 6 months and a range of related symptoms. Item-level analysis suggested generally favourable attitudes towards acupuncture, with 81% expressing interest in acupuncture. Treatment expectancy was moderate overall. Sensitivity and exploratory stratified analyses showed broadly comparable descriptive patterns across demographic and clinical subgroups.</p><p><strong>Conclusion: </strong>Women with self-reported PD showed generally favourable attitudes towards acupuncture and moderate expectancy. Of note, this was found to be a self-selected sample with higher educational attainment that was predominantly interested in acupuncture. Findings reflect perceived acceptability rather than clinical effectiveness or population-level perspectives and should not be generalised. As attitudes were assessed using an adapted, non-validated instrument, results should be interpreted cautiously as indicative of response tendencies. Future research is needed among women not interested in acupuncture and those with a lower educational level to further explore the contextual and experiential factors that potentially shape how acupuncture is perceived and utilised.</p>","PeriodicalId":7257,"journal":{"name":"Acupuncture in Medicine","volume":" ","pages":"9645284261458839"},"PeriodicalIF":2.7,"publicationDate":"2026-07-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148387187","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Periocular acupuncture leading to retinal-choroidal injury: Analysis of clinical features, imaging and treatment follow-up in a highly myopic patient.","authors":"Min Xu, Fang Chen","doi":"10.1177/09645284261454385","DOIUrl":"https://doi.org/10.1177/09645284261454385","url":null,"abstract":"","PeriodicalId":7257,"journal":{"name":"Acupuncture in Medicine","volume":" ","pages":"9645284261454385"},"PeriodicalIF":2.7,"publicationDate":"2026-06-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148306619","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Demographic and clinical profile of acupuncture patients in the Brazilian public health service.","authors":"Hiro N Ynoue, Camilo A C V Dias, João B G da Silva","doi":"10.1177/09645284261458840","DOIUrl":"https://doi.org/10.1177/09645284261458840","url":null,"abstract":"","PeriodicalId":7257,"journal":{"name":"Acupuncture in Medicine","volume":" ","pages":"9645284261458840"},"PeriodicalIF":2.7,"publicationDate":"2026-06-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148262785","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A case of neuromyelitis optica spectrum disorder presenting as intractable hiccups and nausea: A reminder for acupuncture practitioners.","authors":"Dong'e Huang, Jian Liu, Jun-Qing Dong","doi":"10.1177/09645284261457448","DOIUrl":"https://doi.org/10.1177/09645284261457448","url":null,"abstract":"","PeriodicalId":7257,"journal":{"name":"Acupuncture in Medicine","volume":" ","pages":"9645284261457448"},"PeriodicalIF":2.6,"publicationDate":"2026-06-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148248775","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}