Cerebral cortex communications最新文献_第9页

Greater Number of Microglia in Telencephalic Proliferative Zones of Human and Nonhuman Primate Compared with Other Vertebrate Species. 与其他脊椎动物相比，人类和非人灵长类的端脑增殖区有更多的小胶质细胞。

Cerebral cortex communications Pub Date : 2021-09-06 eCollection Date: 2021-01-01 DOI: 10.1093/texcom/tgab053

Elisa Penna, Christopher L Cunningham, Stephanie Saylor, Anna Kreutz, Alice F Tarantal, Verónica Martínez-Cerdeño, Stephen C Noctor

{"title":"Greater Number of Microglia in Telencephalic Proliferative Zones of Human and Nonhuman Primate Compared with Other Vertebrate Species.","authors":"Elisa Penna, Christopher L Cunningham, Stephanie Saylor, Anna Kreutz, Alice F Tarantal, Verónica Martínez-Cerdeño, Stephen C Noctor","doi":"10.1093/texcom/tgab053","DOIUrl":"10.1093/texcom/tgab053","url":null,"abstract":"Microglial cells, the innate immune cells of the brain, are derived from yolk sac precursor cells, begin to colonize the telencephalon at the onset of cortical neurogenesis, and occupy specific layers including the telencephalic proliferative zones. Microglia are an intrinsic component of cortical germinal zones, establish extensive contacts with neural precursor cells (NPCs) and developing cortical vessels, and regulate the size of the NPC pool through mechanisms that include phagocytosis. Microglia exhibit notable differences in number and distribution in the prenatal neocortex between rat and old world nonhuman primate telencephalon, suggesting that microglia possess distinct properties across vertebrate species. To begin addressing this subject, we quantified the number of microglia and NPCs in proliferative zones of the fetal human, rhesus monkey, ferret, and rat, and the prehatch chick and turtle telencephalon. We show that the ratio of NPCs to microglia varies significantly across species. Few microglia populate the prehatch chick telencephalon, but the number of microglia approaches that of NPCs in fetal human and nonhuman primate telencephalon. These data demonstrate that microglia are in a position to perform important functions in a number of vertebrate species but more heavily colonize proliferative zones of fetal human and rhesus monkey telencephalon.","PeriodicalId":72551,"journal":{"name":"Cerebral cortex communications","volume":" ","pages":"tgab053"},"PeriodicalIF":0.0,"publicationDate":"2021-09-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8501267/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39541340","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Fluctuations in Arousal Correlate with Neural Activity in the Human Thalamus. 觉醒的波动与人类丘脑的神经活动有关。

Cerebral cortex communications Pub Date : 2021-09-01 eCollection Date: 2021-01-01 DOI: 10.1093/texcom/tgab055

Tetsuya Iidaka

{"title":"Fluctuations in Arousal Correlate with Neural Activity in the Human Thalamus.","authors":"Tetsuya Iidaka","doi":"10.1093/texcom/tgab055","DOIUrl":"https://doi.org/10.1093/texcom/tgab055","url":null,"abstract":"The neural basis of consciousness has been explored in humans and animals; however, the exact nature of consciousness remains elusive. In this study, we aimed to elucidate which brain regions are relevant to arousal in humans. Simultaneous recordings of brain activity and eye-tracking were conducted in 20 healthy human participants. Brain activity was measured by resting-state functional magnetic resonance imaging with a multiband acquisition protocol. The subjective levels of arousal were investigated based on the degree of eyelid closure that was recorded using a near-infrared eye camera within the scanner. The results showed that the participants were in an aroused state for 79% of the scan time, and the bilateral thalami were significantly associated with the arousal condition. Among the major thalamic subnuclei, the mediodorsal nucleus (MD) showed greater involvement in arousal when compared with other subnuclei. A receiver operating characteristic analysis with leave-one-out crossvalidation conducted using template-based brain activity and arousal-level data from eye-tracking showed that, in most participants, thalamic activity significantly predicted the subjective levels of arousal. These results indicate a significant role of the thalamus, and in particular, the MD, which has rich connectivity with the prefrontal cortices and the limbic system in human consciousness.","PeriodicalId":72551,"journal":{"name":"Cerebral cortex communications","volume":"2 3","pages":"tgab055"},"PeriodicalIF":0.0,"publicationDate":"2021-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8455340/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39466367","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

A Structural Connectivity Disruption One Decade before the Typical Age for Dementia: A Study in Healthy Subjects with Family History of Alzheimer's Disease. 痴呆症典型年龄十年前的结构连接性中断：对有阿尔茨海默病家族史的健康受试者的研究。

Cerebral cortex communications Pub Date : 2021-08-27 eCollection Date: 2021-01-01 DOI: 10.1093/texcom/tgab051

F Ramírez-Toraño, Kausar Abbas, Ricardo Bruña, Silvia Marcos de Pedro, Natividad Gómez-Ruiz, Ana Barabash, Ernesto Pereda, Alberto Marcos, Ramón López-Higes, Fernando Maestu, Joaquín Goñi

{"title":"A Structural Connectivity Disruption One Decade before the Typical Age for Dementia: A Study in Healthy Subjects with Family History of Alzheimer's Disease.","authors":"F Ramírez-Toraño, Kausar Abbas, Ricardo Bruña, Silvia Marcos de Pedro, Natividad Gómez-Ruiz, Ana Barabash, Ernesto Pereda, Alberto Marcos, Ramón López-Higes, Fernando Maestu, Joaquín Goñi","doi":"10.1093/texcom/tgab051","DOIUrl":"10.1093/texcom/tgab051","url":null,"abstract":"The concept of the brain has shifted to a complex system where different subnetworks support the human cognitive functions. Neurodegenerative diseases would affect the interactions among these subnetworks and, the evolution of impairment and the subnetworks involved would be unique for each neurodegenerative disease. In this study, we seek for structural connectivity traits associated with the family history of Alzheimer's disease, that is, early signs of subnetworks impairment due to Alzheimer's disease. The sample in this study consisted of 123 first-degree Alzheimer's disease relatives and 61 nonrelatives. For each subject, structural connectomes were obtained using classical diffusion tensor imaging measures and different resolutions of cortical parcellation. For the whole sample, independent structural-connectome-traits were obtained under the framework of connICA. Finally, we tested the association of the structural-connectome-traits with different factors of relevance for Alzheimer's disease by means of a multiple linear regression. The analysis revealed a structural-connectome-trait obtained from fractional anisotropy associated with the family history of Alzheimer's disease. The structural-connectome-trait presents a reduced fractional anisotropy pattern in first-degree relatives in the tracts connecting posterior areas and temporal areas. The family history of Alzheimer's disease structural-connectome-trait presents a posterior-posterior and posterior-temporal pattern, supplying new evidences to the cascading network failure model.","PeriodicalId":72551,"journal":{"name":"Cerebral cortex communications","volume":" ","pages":"tgab051"},"PeriodicalIF":0.0,"publicationDate":"2021-08-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8501268/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39541338","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The Role of Idiothetic Signals, Landmarks, and Conjunctive Representations in the Development of Place and Head-Direction Cells: A Self-Organizing Neural Network Model. 独特信号、标志和连接表征在位置和头部方向细胞发育中的作用:一个自组织神经网络模型。

Cerebral cortex communications Pub Date : 2021-08-27 eCollection Date: 2022-01-01 DOI: 10.1093/texcom/tgab052

Toby St Clere Smithe, Simon M Stringer

{"title":"The Role of Idiothetic Signals, Landmarks, and Conjunctive Representations in the Development of Place and Head-Direction Cells: A Self-Organizing Neural Network Model.","authors":"Toby St Clere Smithe, Simon M Stringer","doi":"10.1093/texcom/tgab052","DOIUrl":"https://doi.org/10.1093/texcom/tgab052","url":null,"abstract":"Place and head-direction (HD) cells are fundamental to maintaining accurate representations of location and heading in the mammalian brain across sensory conditions, and are thought to underlie path integration-the ability to maintain an accurate representation of location and heading during motion in the dark. Substantial evidence suggests that both populations of spatial cells function as attractor networks, but their developmental mechanisms are poorly understood. We present simulations of a fully self-organizing attractor network model of this process using well-established neural mechanisms. We show that the differential development of the two cell types can be explained by their different idiothetic inputs, even given identical visual signals: HD cells develop when the population receives angular head velocity input, whereas place cells develop when the idiothetic input encodes planar velocity. Our model explains the functional importance of conjunctive \"state-action\" cells, implying that signal propagation delays and a competitive learning mechanism are crucial for successful development. Consequently, we explain how insufficiently rich environments result in pathology: place cell development requires proximal landmarks; conversely, HD cells require distal landmarks. Finally, our results suggest that both networks are instantiations of general mechanisms, and we describe their implications for the neurobiology of spatial processing.","PeriodicalId":72551,"journal":{"name":"Cerebral cortex communications","volume":" ","pages":"tgab052"},"PeriodicalIF":0.0,"publicationDate":"2021-08-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8763244/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39834340","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Task-Irrelevant Semantic Properties of Objects Impinge on Sensory Representations within the Early Visual Cortex. 早期视觉皮层中与任务无关的物体语义特性对感觉表征的影响。

Cerebral cortex communications Pub Date : 2021-08-10 eCollection Date: 2021-01-01 DOI: 10.1093/texcom/tgab049

Joseph C Nah, George L Malcolm, Sarah Shomstein

引用次数: 2

Cerebellar Dentate Connectivity across Adulthood: A Large-Scale Resting State Functional Connectivity Investigation. 成年期小脑齿状体连通性:一项大型静息状态功能连通性调查。

Cerebral cortex communications Pub Date : 2021-08-10 eCollection Date: 2021-01-01 DOI: 10.1093/texcom/tgab050

Jessica A Bernard, Hannah K Ballard, Trevor Bryan Jackson

{"title":"Cerebellar Dentate Connectivity across Adulthood: A Large-Scale Resting State Functional Connectivity Investigation.","authors":"Jessica A Bernard, Hannah K Ballard, Trevor Bryan Jackson","doi":"10.1093/texcom/tgab050","DOIUrl":"https://doi.org/10.1093/texcom/tgab050","url":null,"abstract":"Cerebellar contributions to behavior in advanced age are of interest and importance, given its role in motor and cognitive performance. There are differences and declines in cerebellar structure in advanced age and cerebellar resting state connectivity is lower. However, the work on this area to date has focused on the cerebellar cortex. The deep cerebellar nuclei provide the primary cerebellar inputs and outputs to the cortex, as well as the spinal and vestibular systems. Dentate networks can be dissociated such that the dorsal region is associated with the motor cortex, whereas the ventral aspect is associated with the prefrontal cortex. However, whether dentato-thalamo-cortical networks differ across adulthood remains unknown. Here, using a large adult sample (n = 590) from the Cambridge Center for Ageing and Neuroscience, we investigated dentate connectivity across adulthood. We replicated past work showing dissociable resting state networks in the dorsal and ventral aspects of the dentate. In both seeds, we demonstrated that connectivity is lower with advanced age, indicating that connectivity differences extend beyond the cerebellar cortex. Finally, we demonstrated sex differences in dentate connectivity. This expands our understanding of cerebellar circuitry in advanced age and underscores the potential importance of this structure in age-related performance differences.","PeriodicalId":72551,"journal":{"name":"Cerebral cortex communications","volume":"2 3","pages":"tgab050"},"PeriodicalIF":0.0,"publicationDate":"2021-08-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8436571/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39420839","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 7

Symbols Are Special: An fMRI Adaptation Study of Symbolic, Nonsymbolic, and Non-Numerical Magnitude Processing in the Human Brain. 符号是特殊的:人类大脑中符号、非符号和非数值量级处理的fMRI适应性研究。

Cerebral cortex communications Pub Date : 2021-07-23 eCollection Date: 2021-01-01 DOI: 10.1093/texcom/tgab048

H Moriah Sokolowski, Zachary Hawes, Lien Peters, Daniel Ansari

{"title":"Symbols Are Special: An fMRI Adaptation Study of Symbolic, Nonsymbolic, and Non-Numerical Magnitude Processing in the Human Brain.","authors":"H Moriah Sokolowski, Zachary Hawes, Lien Peters, Daniel Ansari","doi":"10.1093/texcom/tgab048","DOIUrl":"https://doi.org/10.1093/texcom/tgab048","url":null,"abstract":"How are different formats of magnitudes represented in the human brain? We used functional magnetic resonance imaging adaptation to isolate representations of symbols, quantities, and physical size in 45 adults. Results indicate that the neural correlates supporting the passive processing of number symbols are largely dissociable from those supporting quantities and physical size, anatomically and representationally. Anatomically, passive processing of quantities and size correlate with activation in the right intraparietal sulcus, whereas symbolic number processing, compared with quantity processing, correlates with activation in the left inferior parietal lobule. Representationally, neural patterns of activation supporting symbols are dissimilar from neural activation patterns supporting quantity and size in the bilateral parietal lobes. These findings challenge the longstanding notion that the culturally acquired ability to conceptualize symbolic numbers is represented using entirely the same brain systems that support the evolutionarily ancient system used to process quantities. Moreover, these data reveal that regions that support numerical magnitude processing are also important for the processing of non-numerical magnitudes. This discovery compels future investigations of the neural consequences of acquiring knowledge of symbolic numbers.","PeriodicalId":72551,"journal":{"name":"Cerebral cortex communications","volume":"2 3","pages":"tgab048"},"PeriodicalIF":0.0,"publicationDate":"2021-07-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8382912/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39356485","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 11

Binary Semantic Classification Using Cortical Activation with Pavlovian-Conditioned Vestibular Responses in Healthy and Locked-In Individuals. 健康和闭锁个体巴甫洛夫条件前庭反应皮质激活的二元语义分类。

Cerebral cortex communications Pub Date : 2021-07-23 eCollection Date: 2021-01-01 DOI: 10.1093/texcom/tgab046

Natsue Yoshimura, Kaito Umetsu, Alessandro Tonin, Yasuhisa Maruyama, Kyosuke Harada, Aygul Rana, Gowrishankar Ganesh, Ujwal Chaudhary, Yasuharu Koike, Niels Birbaumer

{"title":"Binary Semantic Classification Using Cortical Activation with Pavlovian-Conditioned Vestibular Responses in Healthy and Locked-In Individuals.","authors":"Natsue Yoshimura, Kaito Umetsu, Alessandro Tonin, Yasuhisa Maruyama, Kyosuke Harada, Aygul Rana, Gowrishankar Ganesh, Ujwal Chaudhary, Yasuharu Koike, Niels Birbaumer","doi":"10.1093/texcom/tgab046","DOIUrl":"https://doi.org/10.1093/texcom/tgab046","url":null,"abstract":"To develop a more reliable brain-computer interface (BCI) for patients in the completely locked-in state (CLIS), here we propose a Pavlovian conditioning paradigm using galvanic vestibular stimulation (GVS), which can induce a strong sensation of equilibrium distortion in individuals. We hypothesized that associating two different sensations caused by two-directional GVS with the thoughts of \"yes\" and \"no\" by individuals would enable us to emphasize the differences in brain activity associated with the thoughts of yes and no and hence help us better distinguish the two from electroencephalography (EEG). We tested this hypothesis with 11 healthy and 1 CLIS participant. Our results showed that, first, conditioning of GVS with the thoughts of yes and no is possible. And second, the classification of whether an individual is thinking \"yes\" or \"no\" is significantly improved after the conditioning, even in the absence of subsequent GVS stimulations. We observed average classification accuracy of 73.0% over 11 healthy individuals and 85.3% with the CLIS patient. These results suggest the establishment of GVS-based Pavlovian conditioning and its usability as a noninvasive BCI.","PeriodicalId":72551,"journal":{"name":"Cerebral cortex communications","volume":"2 3","pages":"tgab046"},"PeriodicalIF":0.0,"publicationDate":"2021-07-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8382900/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39356483","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Neural Responses of Pet Dogs Witnessing Their Caregiver's Positive Interactions with a Conspecific: An fMRI Study. 宠物狗目睹其看护人与特定个体的积极互动时的神经反应：一项功能磁共振成像研究。

Cerebral cortex communications Pub Date : 2021-07-19 eCollection Date: 2021-01-01 DOI: 10.1093/texcom/tgab047

Sabrina Karl, Ronald Sladky, Claus Lamm, Ludwig Huber

{"title":"Neural Responses of Pet Dogs Witnessing Their Caregiver's Positive Interactions with a Conspecific: An fMRI Study.","authors":"Sabrina Karl, Ronald Sladky, Claus Lamm, Ludwig Huber","doi":"10.1093/texcom/tgab047","DOIUrl":"10.1093/texcom/tgab047","url":null,"abstract":"We have limited knowledge on how dogs perceive humans and their actions. Various researchers investigated how they process human facial expressions, but their brain responses to complex social scenarios remain unclear. While undergoing fMRI, we exposed pet dogs to videos showing positive social and neutral nonsocial interactions between their caregivers and another conspecific. Our main interest was how the dogs responded to their caregivers (compared to a stranger) engaging in a pleasant interaction with another dog that could be seen as social rival. We hypothesized that the dogs would show activation increases in limbic areas such as the amygdala, hypothalamus, and insula and likely show higher attention and arousal during the positive caregiver-dog interaction. When contrasting the social with the nonsocial interaction, we found increased activations in the left amygdala and the insular cortex. Crucially, the dogs' hypothalamus showed strongest activation when the caregiver engaged in a positive social interaction. These findings indicate that dogs are sensitive to social affective human-dog interactions and likely show higher valence attribution and arousal in a situation possibly perceived as a potential threat to their caregiver bonds. Our study provides a first window into the neural correlates of social and emotional processing in dogs.","PeriodicalId":72551,"journal":{"name":"Cerebral cortex communications","volume":"2 3","pages":"tgab047"},"PeriodicalIF":0.0,"publicationDate":"2021-07-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8382916/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39356484","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Detailed Episodic Memory Depends on Concurrent Reactivation of Basic Visual Features within the Posterior Hippocampus and Early Visual Cortex. 详细情景记忆依赖于海马后部和早期视觉皮层内基本视觉特征的同步再激活。

Cerebral cortex communications Pub Date : 2021-07-16 eCollection Date: 2021-01-01 DOI: 10.1093/texcom/tgab045

Michael B Bone, Bradley R Buchsbaum

{"title":"Detailed Episodic Memory Depends on Concurrent Reactivation of Basic Visual Features within the Posterior Hippocampus and Early Visual Cortex.","authors":"Michael B Bone, Bradley R Buchsbaum","doi":"10.1093/texcom/tgab045","DOIUrl":"https://doi.org/10.1093/texcom/tgab045","url":null,"abstract":"The hippocampus is a key brain region for the storage and retrieval of episodic memories, but how it performs this function is unresolved. Leading theories posit that the hippocampus stores a sparse representation, or \"index,\" of the pattern of neocortical activity that occurred during perception. During retrieval, reactivation of the index by a partial cue facilitates the reactivation of the associated neocortical pattern. Therefore, episodic retrieval requires joint reactivation of the hippocampal index and the associated neocortical networks. To test this theory, we examine the relation between performance on a recognition memory task requiring retrieval of image-specific visual details and feature-specific reactivation within the hippocampus and neocortex. We show that trial-by-trial recognition accuracy correlates with neural reactivation of low-level features (e.g., luminosity and edges) within the posterior hippocampus and early visual cortex for participants with high recognition lure accuracy. As predicted, the two regions interact, such that recognition accuracy correlates with hippocampal reactivation only when reactivation co-occurs within the early visual cortex (and vice versa). In addition to supporting leading theories of hippocampal function, our findings show large individual differences in the features underlying visual memory and suggest that the anterior and posterior hippocampus represents gist-like and detailed features, respectively.","PeriodicalId":72551,"journal":{"name":"Cerebral cortex communications","volume":"2 3","pages":"tgab045"},"PeriodicalIF":0.0,"publicationDate":"2021-07-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8370760/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39329595","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 10