Brain and neuroscience advances最新文献_第9页

The genetics of neuropsychiatric disorders. 神经精神疾病的遗传学。

Brain and neuroscience advances Pub Date : 2019-05-30 Epub Date: 2018-10-12 DOI: 10.1177/2398212818799271

Nicholas J Bray, Michael C O'Donovan

引用次数: 58

Can the endocannabinoid receptor system reduce neuronal inflammation in arthritis 内源性大麻素受体系统能减轻关节炎的神经炎症吗

Brain and neuroscience advances Pub Date : 2019-05-23 DOI: 10.1177/2398212819855490

D. Gibson, E. Murray, S. Watterson

引用次数: 1

Persistent memories of long-term potentiation and the N-methyl-d-aspartate receptor. 长期增强的持久记忆和n -甲基-d-天冬氨酸受体。

Brain and neuroscience advances Pub Date : 2019-05-21 eCollection Date: 2019-01-01 DOI: 10.1177/2398212819848213

Tvp Bliss, G L Collingridge

引用次数: 24

Half a century of handedness research: Myths, truths; fictions, facts; backwards, but mostly forwards. 半个世纪的惯用手研究:神话，真相;小说,事实;向后，但主要是向前。

Brain and neuroscience advances Pub Date : 2019-05-06 eCollection Date: 2019-01-01 DOI: 10.1177/2398212818820513

Chris McManus

{"title":"Half a century of handedness research: Myths, truths; fictions, facts; backwards, but mostly forwards.","authors":"Chris McManus","doi":"10.1177/2398212818820513","DOIUrl":"10.1177/2398212818820513","url":null,"abstract":"Although most people are right-handed and have language in their left cerebral hemisphere, why that is so, and in particular why about ten per cent of people are left-handed, is far from clear. Multiple theories have been proposed, often with little in the way of empirical support, and sometimes indeed with strong evidence against them, and yet despite that have become modern urban myths, probably due to the symbolic power of right and left. One thinks in particular of ideas of being right-brained or left-brained, of suggestions that left-handedness is due to perinatal brain damage, of claims that left-handers die seven years earlier than right-handers, and of the unfalsifiable ramifications of the byzantine Geschwind-Behan-Galaburda theory. This article looks back over the past fifty years of research on brain asymmetries, exploring the different themes and approaches, sometimes in relation to the author's own work. Taking all of the work together it is probable that cerebral asymmetries are under genetic control, probably with multiple genetic loci, only a few of which are now beginning to be found thanks to very large databases that are becoming available. Other progress is also seen in proper meta-analyses, the use of fMRI for studying multiple functional lateralisations in large number of individuals, fetal ultra-sound for assessing handedness before birth, and fascinating studies of lateralisation in an ever widening range of animal species. With luck the next fifty years will make more progress and show fewer false directions than had much of the work in the previous fifty years.","PeriodicalId":72444,"journal":{"name":"Brain and neuroscience advances","volume":" ","pages":"2398212818820513"},"PeriodicalIF":0.0,"publicationDate":"2019-05-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1177/2398212818820513","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"37733056","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 48

Promoting and supporting credibility in neuroscience. 促进和支持神经科学的可信度。

Brain and neuroscience advances Pub Date : 2019-04-10 eCollection Date: 2019-01-01 DOI: 10.1177/2398212819844167

Guillaume A Rousselet, Georgina Hazell, Anne Cooke, Jeffrey W Dalley

引用次数: 0

Acetylcholine and cholinergic receptors. 乙酰胆碱和胆碱能受体。

Brain and neuroscience advances Pub Date : 2019-03-21 eCollection Date: 2019-01-01 DOI: 10.1177/2398212818820506

David A Brown

引用次数: 36

Starting and stopping movement by the primate brain. 灵长类动物大脑开始和停止运动。

Brain and neuroscience advances Pub Date : 2019-03-15 eCollection Date: 2019-01-01 DOI: 10.1177/2398212819837149

Roger Lemon, Alexander Kraskov

引用次数: 6

A future for neuronal oscillation research. 神经元振荡研究的未来。

Brain and neuroscience advances Pub Date : 2019-03-01 eCollection Date: 2018-01-01 DOI: 10.1177/2398212818794827

Miles A Whittington, Roger D Traub, Natalie E Adams

{"title":"A future for neuronal oscillation research.","authors":"Miles A Whittington, Roger D Traub, Natalie E Adams","doi":"10.1177/2398212818794827","DOIUrl":"https://doi.org/10.1177/2398212818794827","url":null,"abstract":"Neuronal oscillations represent the most obvious feature of electrical activity in the brain. They are linked in general with global brain state (awake, asleep, etc.) and specifically with organisation of neuronal outputs during sensory perception and cognitive processing. Oscillations can be generated by individual neurons on the basis of interaction between inputs and intrinsic conductances but are far more commonly seen at the local network level in populations of interconnected neurons with diverse arrays of functional properties. It is at this level that the brain's rich and diverse library of oscillatory time constants serve to temporally organise large-scale neural activity patterns. The discipline is relatively mature at the microscopic (cell, local network) level - although novel discoveries are still commonplace - but requires a far greater understanding of mesoscopic and macroscopic brain dynamics than we currently hold. Without this, extrapolation from the temporal properties of neurons and their communication strategies up to whole brain function will remain largely theoretical. However, recent advances in large-scale neuronal population recordings and more direct, higher fidelity, non-invasive measurement of whole brain function suggest much progress is just around the corner.","PeriodicalId":72444,"journal":{"name":"Brain and neuroscience advances","volume":"2 ","pages":"2398212818794827"},"PeriodicalIF":0.0,"publicationDate":"2019-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1177/2398212818794827","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"37732196","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 13

Neuroethical issues in cognitive enhancement: Modafinil as the example of a workplace drug? 认知增强中的神经伦理问题:莫达非尼作为工作场所用药的例子?

Brain and neuroscience advances Pub Date : 2019-02-15 eCollection Date: 2019-01-01 DOI: 10.1177/2398212818816018

Annette B Brühl, Camilla d'Angelo, Barbara J Sahakian

{"title":"Neuroethical issues in cognitive enhancement: Modafinil as the example of a workplace drug?","authors":"Annette B Brühl, Camilla d'Angelo, Barbara J Sahakian","doi":"10.1177/2398212818816018","DOIUrl":"https://doi.org/10.1177/2398212818816018","url":null,"abstract":"The use of cognitive-enhancing drugs by healthy individuals has been a feature for much of recorded history. Cocaine and amphetamine are modern cases of drugs initially enthusiastically acclaimed for enhancing cognition and mood. Today, an increasing number of healthy people are reported to use cognitive-enhancing drugs, as well as other interventions, such as non-invasive brain stimulation, to maintain or improve work performance. Cognitive-enhancing drugs, such as methylphenidate and modafinil, which were developed as treatments, are increasingly being used by healthy people. Modafinil not only affects 'cold' cognition, but also improves 'hot' cognition, such as emotion recognition and task-related motivation. The lifestyle use of 'smart drugs' raises both safety concerns as well as ethical issues, including coercion and increasing disparity in society. As a society, we need to consider which forms of cognitive enhancement (e.g. pharmacological, exercise, lifelong learning) are acceptable and for which groups under what conditions and by what methods we would wish to improve and flourish.","PeriodicalId":72444,"journal":{"name":"Brain and neuroscience advances","volume":" ","pages":"2398212818816018"},"PeriodicalIF":0.0,"publicationDate":"2019-02-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1177/2398212818816018","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"37733052","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 26

Corrigendum. 勘误表。

Brain and neuroscience advances Pub Date : 2019-01-23 eCollection Date: 2019-01-01 DOI: 10.1177/2398212819829629

引用次数: 0